2C8AA

Structure of the wild-type c3bot1 exoenzyme (nicotinamide-bound state, crystal form i)
Total Genus 71
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
71
sequence length
208
structure length
208
Chain Sequence
NTYQEFTNIDQAKAWGNAQYKKYGLSKSEKEAIVSYTKSASEINGKLRQNKGVINGFPSNLIKQVELLDKSFNKMKTPENIMLFRGDDPAYLGTEFQNTLLNSNGTINKTAFEKAKAKFLNKDRLEYGYISTSLMNVSQFAGRPIITKFKVAKGSKAGYIDPISAFAGQLEMLLPRHSTYHIDDMRLSSDGKQIIITATMMGTAINPK
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural Basis for the Nad-Hydrolysis Mechanism and the Artt-Loop Plasticity of C3 Exoenzymes.
pubmed doi rcsb
molecule tags Transferase
source organism Clostridium botulinum
molecule keywords MONO-ADP-RIBOSYLTRANSFERASE C3
total genus 71
structure length 208
sequence length 208
chains with identical sequence B, C, D
ec nomenclature ec 2.4.2.-:
pdb deposition date 2005-12-03
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.176.10 Alpha Beta Alpha-Beta Complex Toxin ADP-ribosyltransferase; Chain A, domain 1 Toxin ADP-ribosyltransferase; Chain A, domain 1 2c8aA00
4XSGB 4PKVA 1R45A 1UZIA 4H0YA 1PWPA 1PWVA 4H0VA 4GY2A 4H0TA 5D1TA 1OJZA 2C8CA 2C8FE 3U0JA 4PKSA 2C8HA 1R4BA 1OG3A 2C89A 2BOVB 1OG1A 1GIQA 1GZEA 1J7NA 4GF1A 4PKTA 1QS1A 1PWUA 2WN4A 2J3ZA 4PKRA 4WF6A 3NTSA 2WN8A 4FMLA 1JKYA 2J3VA 4ELNA 2WN7A 3BW8A 1G24A 5DZQA 4PKUA 2GWMA 1GIRA 1GY0A 5H04A 1YQYA 4PKQA 5BWMB 2GWLA 4PKWA 2J3XA 4DV8A 1OJQA 4FK7A 4TR5A 4XM7A 1QS2A 4H03A 1PWQA 2C8GA 1PWWA 5GTTA 2C8DA 1GXYA 2WN5A 1GXZA 2C8BX 2C8EE 5H03A 4H0XA 1OG4A 1ZXVA 4FXQA 3BUZA 1GZFA 4XM8A 2A78B 4XM6A 2C8AA 5D1UA 2A9KB 2WN6A 5D1SA 4XSHB
chains in the Genus database with same CATH superfamily
4XSGB 4PKVA 1R45A 1UZIA 4H0YA 1PWPA 1PWVA 4H0VA 4GY2A 4H0TA 5D1TA 1OJZA 2C8CA 2C8FE 3U0JA 4PKSA 2C8HA 1R4BA 1OG3A 2C89A 2BOVB 1OG1A 1GIQA 1GZEA 1J7NA 4GF1A 4PKTA 1QS1A 1PWUA 2WN4A 2J3ZA 4PKRA 4WF6A 3NTSA 2WN8A 4FMLA 1JKYA 2J3VA 4ELNA 2WN7A 3BW8A 1G24A 5DZQA 4PKUA 2GWMA 1GIRA 1GY0A 5H04A 1YQYA 4PKQA 5BWMB 2GWLA 4PKWA 2J3XA 4DV8A 1OJQA 4FK7A 4TR5A 4XM7A 1QS2A 4H03A 1PWQA 2C8GA 1PWWA 5GTTA 2C8DA 1GXYA 2WN5A 1GXZA 2C8BX 2C8EE 5H03A 4H0XA 1OG4A 1ZXVA 4FXQA 3BUZA 1GZFA 4XM8A 2A78B 4XM6A 2C8AA 5D1UA 2A9KB 2WN6A 5D1SA 4XSHB
chains in the Genus database with same CATH topology
4XSGB 4PKVA 1R45A 1UZIA 4H0YA 1PWPA 1PWVA 4H0VA 4GY2A 4H0TA 5D1TA 1OJZA 2C8CA 2C8FE 3U0JA 4PKSA 2C8HA 1R4BA 1OG3A 2C89A 2BOVB 1OG1A 1GIQA 1GZEA 1J7NA 4GF1A 4PKTA 1QS1A 1PWUA 2WN4A 2J3ZA 4PKRA 4WF6A 3NTSA 2WN8A 4FMLA 1JKYA 2J3VA 4ELNA 2WN7A 3BW8A 1G24A 5DZQA 4PKUA 2GWMA 1GIRA 1GY0A 5H04A 1YQYA 4PKQA 5BWMB 2GWLA 4PKWA 2J3XA 4DV8A 1OJQA 4FK7A 4TR5A 4XM7A 1QS2A 4H03A 1PWQA 2C8GA 1PWWA 5GTTA 2C8DA 1GXYA 2WN5A 1GXZA 2C8BX 2C8EE 5H03A 4H0XA 1OG4A 1ZXVA 4FXQA 3BUZA 1GZFA 4XM8A 2A78B 4XM6A 2C8AA 5D1UA 2A9KB 2WN6A 5D1SA 4XSHB
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4XSG B;  4PKV A;  1R45 A;  1UZI A;  4H0Y A;  1PWP A;  1PWV A;  4H0V A;  4GY2 A;  4H0T A;  5D1T A;  1OJZ A;  2C8C A;  2C8F E;  3U0J A;  4PKS A;  2C8H A;  1R4B A;  1OG3 A;  2C89 A;  2BOV B;  1OG1 A;  1GIQ A;  1GZE A;  1J7N A;  4GF1 A;  4PKT A;  1QS1 A;  1PWU A;  2WN4 A;  2J3Z A;  4PKR A;  4WF6 A;  3NTS A;  2WN8 A;  4FML A;  1JKY A;  2J3V A;  4ELN A;  2WN7 A;  3BW8 A;  1G24 A;  5DZQ A;  4PKU A;  2GWM A;  1GIR A;  1GY0 A;  5H04 A;  1YQY A;  4PKQ A;  5BWM B;  2GWL A;  4PKW A;  2J3X A;  4DV8 A;  1OJQ A;  4FK7 A;  4TR5 A;  4XM7 A;  1QS2 A;  4H03 A;  1PWQ A;  2C8G A;  1PWW A;  5GTT A;  2C8D A;  1GXY A;  2WN5 A;  1GXZ A;  2C8B X;  2C8E E;  5H03 A;  4H0X A;  1OG4 A;  1ZXV A;  4FXQ A;  3BUZ A;  1GZF A;  4XM8 A;  2A78 B;  4XM6 A;  2C8A A;  5D1U A;  2A9K B;  2WN6 A;  5D1S A;  4XSH B; 
#chains in the Genus database with same CATH topology
 4XSG B;  4PKV A;  1R45 A;  1UZI A;  4H0Y A;  1PWP A;  1PWV A;  4H0V A;  4GY2 A;  4H0T A;  5D1T A;  1OJZ A;  2C8C A;  2C8F E;  3U0J A;  4PKS A;  2C8H A;  1R4B A;  1OG3 A;  2C89 A;  2BOV B;  1OG1 A;  1GIQ A;  1GZE A;  1J7N A;  4GF1 A;  4PKT A;  1QS1 A;  1PWU A;  2WN4 A;  2J3Z A;  4PKR A;  4WF6 A;  3NTS A;  2WN8 A;  4FML A;  1JKY A;  2J3V A;  4ELN A;  2WN7 A;  3BW8 A;  1G24 A;  5DZQ A;  4PKU A;  2GWM A;  1GIR A;  1GY0 A;  5H04 A;  1YQY A;  4PKQ A;  5BWM B;  2GWL A;  4PKW A;  2J3X A;  4DV8 A;  1OJQ A;  4FK7 A;  4TR5 A;  4XM7 A;  1QS2 A;  4H03 A;  1PWQ A;  2C8G A;  1PWW A;  5GTT A;  2C8D A;  1GXY A;  2WN5 A;  1GXZ A;  2C8B X;  2C8E E;  5H03 A;  4H0X A;  1OG4 A;  1ZXV A;  4FXQ A;  3BUZ A;  1GZF A;  4XM8 A;  2A78 B;  4XM6 A;  2C8A A;  5D1U A;  2A9K B;  2WN6 A;  5D1S A;  4XSH B; 
#chains in the Genus database with same CATH homology
 4XSG B;  4PKV A;  1R45 A;  1UZI A;  4H0Y A;  1PWP A;  1PWV A;  4H0V A;  4GY2 A;  4H0T A;  5D1T A;  1OJZ A;  2C8C A;  2C8F E;  3U0J A;  4PKS A;  2C8H A;  1R4B A;  1OG3 A;  2C89 A;  2BOV B;  1OG1 A;  1GIQ A;  1GZE A;  1J7N A;  4GF1 A;  4PKT A;  1QS1 A;  1PWU A;  2WN4 A;  2J3Z A;  4PKR A;  4WF6 A;  3NTS A;  2WN8 A;  4FML A;  1JKY A;  2J3V A;  4ELN A;  2WN7 A;  3BW8 A;  1G24 A;  5DZQ A;  4PKU A;  2GWM A;  1GIR A;  1GY0 A;  5H04 A;  1YQY A;  4PKQ A;  5BWM B;  2GWL A;  4PKW A;  2J3X A;  4DV8 A;  1OJQ A;  4FK7 A;  4TR5 A;  4XM7 A;  1QS2 A;  4H03 A;  1PWQ A;  2C8G A;  1PWW A;  5GTT A;  2C8D A;  1GXY A;  2WN5 A;  1GXZ A;  2C8B X;  2C8E E;  5H03 A;  4H0X A;  1OG4 A;  1ZXV A;  4FXQ A;  3BUZ A;  1GZF A;  4XM8 A;  2A78 B;  4XM6 A;  2C8A A;  5D1U A;  2A9K B;  2WN6 A;  5D1S A;  4XSH B; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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