2C8GA

Structure of the pn loop q182a mutant c3bot1 exoenzyme (free state, crystal form i)
Total Genus 69
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
69
sequence length
207
structure length
207
Chain Sequence
NTYQEFTNIDQAKAWGNAQYKKYGLSKSEKEAIVSYTKSASEINGKLRQNKGVINGFPSNLIKQVELLDKSFNKMKTPENIMLFRGDDPAYLGTEFQNTLLNSNGTINKTAFEKAKAKFLNKDRLEYGYISTSLMNVSAFAGRPIITKFKVAKGSKAGYIDPISAFAGQLEMLLPRHSTYHIDDMRLSSDGKQIIITATMMGTAINP
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural Properties of Wild-Type and Two Artt Motif Mutants Clostridium Botulinum C3 Exoenzyme Isoform 1 in Different Substrate Complexed States and Crystal Forms.
rcsb
molecule tags Transferase
source organism Clostridium botulinum
molecule keywords MONO-ADP-RIBOSYLTRANSFERASE C3
total genus 69
structure length 207
sequence length 207
chains with identical sequence B, C, D
ec nomenclature ec 2.4.2.-:
pdb deposition date 2005-12-03

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF03496 ADPrib_exo_Tox ADP-ribosyltransferase exoenzyme
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.176.10 Alpha Beta Alpha-Beta Complex Toxin ADP-ribosyltransferase; Chain A, domain 1 Toxin ADP-ribosyltransferase; Chain A, domain 1 2c8gA00
2GWLA 1UZIA 2C8FE 4DV8A 2WN4A 4FXQA 2C8DA 4PKUA 2WN5A 4H03A 4PKWA 2C8GA 1R4BA 1GZEA 4H0YA 1GXYA 1GZFA 1ZXVA 2J3XA 5D1TA 1PWVA 2C8HA 1OJZA 2BOVB 1OG4A 5D1UA 1PWWA 1QS2A 2A78B 1G24A 5H04A 1JKYA 4XM7A 5BWMB 3NTSA 2WN7A 1OG3A 5H03A 2WN6A 4PKTA 1OG1A 1R45A 2J3ZA 2J3VA 2C89A 4PKVA 1PWQA 5GTTA 4ELNA 4FMLA 2WN8A 5D1SA 3BW8A 5DZQA 4H0TA 4GF1A 4PKSA 1OJQA 4PKQA 4H0XA 2C8BX 1J7NA 2GWMA 2A9KB 4FK7A 4XSHB 2C8EE 1PWUA 3U0JA 1PWPA 3BUZA 4TR5A 1GY0A 1GIQA 4WF6A 4XM8A 1GIRA 2C8AA 4XSGB 1GXZA 2C8CA 1QS1A 4GY2A 4XM6A 4PKRA 1YQYA 4H0VA
chains in the Genus database with same CATH superfamily
2GWLA 1UZIA 2C8FE 4DV8A 2WN4A 4FXQA 2C8DA 4PKUA 2WN5A 4H03A 4PKWA 2C8GA 1R4BA 1GZEA 4H0YA 1GXYA 1GZFA 1ZXVA 2J3XA 5D1TA 1PWVA 2C8HA 1OJZA 2BOVB 1OG4A 5D1UA 1PWWA 1QS2A 2A78B 1G24A 5H04A 1JKYA 4XM7A 5BWMB 3NTSA 2WN7A 1OG3A 5H03A 2WN6A 4PKTA 1OG1A 1R45A 2J3ZA 2J3VA 2C89A 4PKVA 1PWQA 5GTTA 4ELNA 4FMLA 2WN8A 5D1SA 3BW8A 5DZQA 4H0TA 4GF1A 4PKSA 1OJQA 4PKQA 4H0XA 2C8BX 1J7NA 2GWMA 2A9KB 4FK7A 4XSHB 2C8EE 1PWUA 3U0JA 1PWPA 3BUZA 4TR5A 1GY0A 1GIQA 4WF6A 4XM8A 1GIRA 2C8AA 4XSGB 1GXZA 2C8CA 1QS1A 4GY2A 4XM6A 4PKRA 1YQYA 4H0VA
chains in the Genus database with same CATH topology
2GWLA 1UZIA 2C8FE 4DV8A 2WN4A 4FXQA 2C8DA 4PKUA 2WN5A 4H03A 4PKWA 2C8GA 1R4BA 1GZEA 4H0YA 1GXYA 1GZFA 1ZXVA 2J3XA 5D1TA 1PWVA 2C8HA 1OJZA 2BOVB 1OG4A 5D1UA 1PWWA 1QS2A 2A78B 1G24A 5H04A 1JKYA 4XM7A 5BWMB 3NTSA 2WN7A 1OG3A 5H03A 2WN6A 4PKTA 1OG1A 1R45A 2J3ZA 2J3VA 2C89A 4PKVA 1PWQA 5GTTA 4ELNA 4FMLA 2WN8A 5D1SA 3BW8A 5DZQA 4H0TA 4GF1A 4PKSA 1OJQA 4PKQA 4H0XA 2C8BX 1J7NA 2GWMA 2A9KB 4FK7A 4XSHB 2C8EE 1PWUA 3U0JA 1PWPA 3BUZA 4TR5A 1GY0A 1GIQA 4WF6A 4XM8A 1GIRA 2C8AA 4XSGB 1GXZA 2C8CA 1QS1A 4GY2A 4XM6A 4PKRA 1YQYA 4H0VA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2GWL A;  1UZI A;  2C8F E;  4DV8 A;  2WN4 A;  4FXQ A;  2C8D A;  4PKU A;  2WN5 A;  4H03 A;  4PKW A;  2C8G A;  1R4B A;  1GZE A;  4H0Y A;  1GXY A;  1GZF A;  1ZXV A;  2J3X A;  5D1T A;  1PWV A;  2C8H A;  1OJZ A;  2BOV B;  1OG4 A;  5D1U A;  1PWW A;  1QS2 A;  2A78 B;  1G24 A;  5H04 A;  1JKY A;  4XM7 A;  5BWM B;  3NTS A;  2WN7 A;  1OG3 A;  5H03 A;  2WN6 A;  4PKT A;  1OG1 A;  1R45 A;  2J3Z A;  2J3V A;  2C89 A;  4PKV A;  1PWQ A;  5GTT A;  4ELN A;  4FML A;  2WN8 A;  5D1S A;  3BW8 A;  5DZQ A;  4H0T A;  4GF1 A;  4PKS A;  1OJQ A;  4PKQ A;  4H0X A;  2C8B X;  1J7N A;  2GWM A;  2A9K B;  4FK7 A;  4XSH B;  2C8E E;  1PWU A;  3U0J A;  1PWP A;  3BUZ A;  4TR5 A;  1GY0 A;  1GIQ A;  4WF6 A;  4XM8 A;  1GIR A;  2C8A A;  4XSG B;  1GXZ A;  2C8C A;  1QS1 A;  4GY2 A;  4XM6 A;  4PKR A;  1YQY A;  4H0V A; 
#chains in the Genus database with same CATH topology
 2GWL A;  1UZI A;  2C8F E;  4DV8 A;  2WN4 A;  4FXQ A;  2C8D A;  4PKU A;  2WN5 A;  4H03 A;  4PKW A;  2C8G A;  1R4B A;  1GZE A;  4H0Y A;  1GXY A;  1GZF A;  1ZXV A;  2J3X A;  5D1T A;  1PWV A;  2C8H A;  1OJZ A;  2BOV B;  1OG4 A;  5D1U A;  1PWW A;  1QS2 A;  2A78 B;  1G24 A;  5H04 A;  1JKY A;  4XM7 A;  5BWM B;  3NTS A;  2WN7 A;  1OG3 A;  5H03 A;  2WN6 A;  4PKT A;  1OG1 A;  1R45 A;  2J3Z A;  2J3V A;  2C89 A;  4PKV A;  1PWQ A;  5GTT A;  4ELN A;  4FML A;  2WN8 A;  5D1S A;  3BW8 A;  5DZQ A;  4H0T A;  4GF1 A;  4PKS A;  1OJQ A;  4PKQ A;  4H0X A;  2C8B X;  1J7N A;  2GWM A;  2A9K B;  4FK7 A;  4XSH B;  2C8E E;  1PWU A;  3U0J A;  1PWP A;  3BUZ A;  4TR5 A;  1GY0 A;  1GIQ A;  4WF6 A;  4XM8 A;  1GIR A;  2C8A A;  4XSG B;  1GXZ A;  2C8C A;  1QS1 A;  4GY2 A;  4XM6 A;  4PKR A;  1YQY A;  4H0V A; 
#chains in the Genus database with same CATH homology
 2GWL A;  1UZI A;  2C8F E;  4DV8 A;  2WN4 A;  4FXQ A;  2C8D A;  4PKU A;  2WN5 A;  4H03 A;  4PKW A;  2C8G A;  1R4B A;  1GZE A;  4H0Y A;  1GXY A;  1GZF A;  1ZXV A;  2J3X A;  5D1T A;  1PWV A;  2C8H A;  1OJZ A;  2BOV B;  1OG4 A;  5D1U A;  1PWW A;  1QS2 A;  2A78 B;  1G24 A;  5H04 A;  1JKY A;  4XM7 A;  5BWM B;  3NTS A;  2WN7 A;  1OG3 A;  5H03 A;  2WN6 A;  4PKT A;  1OG1 A;  1R45 A;  2J3Z A;  2J3V A;  2C89 A;  4PKV A;  1PWQ A;  5GTT A;  4ELN A;  4FML A;  2WN8 A;  5D1S A;  3BW8 A;  5DZQ A;  4H0T A;  4GF1 A;  4PKS A;  1OJQ A;  4PKQ A;  4H0X A;  2C8B X;  1J7N A;  2GWM A;  2A9K B;  4FK7 A;  4XSH B;  2C8E E;  1PWU A;  3U0J A;  1PWP A;  3BUZ A;  4TR5 A;  1GY0 A;  1GIQ A;  4WF6 A;  4XM8 A;  1GIR A;  2C8A A;  4XSG B;  1GXZ A;  2C8C A;  1QS1 A;  4GY2 A;  4XM6 A;  4PKR A;  1YQY A;  4H0V A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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