2C8GA

Structure of the pn loop q182a mutant c3bot1 exoenzyme (free state, crystal form i)
Total Genus 69
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
69
sequence length
207
structure length
207
Chain Sequence
NTYQEFTNIDQAKAWGNAQYKKYGLSKSEKEAIVSYTKSASEINGKLRQNKGVINGFPSNLIKQVELLDKSFNKMKTPENIMLFRGDDPAYLGTEFQNTLLNSNGTINKTAFEKAKAKFLNKDRLEYGYISTSLMNVSAFAGRPIITKFKVAKGSKAGYIDPISAFAGQLEMLLPRHSTYHIDDMRLSSDGKQIIITATMMGTAINP
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural Properties of Wild-Type and Two Artt Motif Mutants Clostridium Botulinum C3 Exoenzyme Isoform 1 in Different Substrate Complexed States and Crystal Forms.
rcsb
molecule tags Transferase
source organism Clostridium botulinum
molecule keywords MONO-ADP-RIBOSYLTRANSFERASE C3
total genus 69
structure length 207
sequence length 207
chains with identical sequence B, C, D
ec nomenclature ec 2.4.2.-:
pdb deposition date 2005-12-03

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF03496 ADPrib_exo_Tox ADP-ribosyltransferase exoenzyme
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.176.10 Alpha Beta Alpha-Beta Complex Toxin ADP-ribosyltransferase; Chain A, domain 1 Toxin ADP-ribosyltransferase; Chain A, domain 1 2c8gA00
1R45A 2GWMA 1G24A 1GXZA 2C8FE 1QS1A 1PWPA 1R4BA 1JKYA 2C8DA 1GY0A 4GY2A 4PKVA 2WN6A 4PKUA 4PKSA 4PKQA 1PWQA 1ZXVA 1OG3A 4XSHB 4PKTA 4XM7A 1OG4A 4H0YA 5BWMB 1PWVA 1YQYA 1UZIA 2C8EE 4FMLA 3NTSA 2C8AA 4DV8A 4XM6A 4FXQA 4H0TA 2C89A 2C8GA 5H04A 2WN7A 2WN8A 5H03A 5D1UA 5GTTA 5D1SA 1GZEA 2GWLA 2J3XA 2C8CA 1PWWA 1GIRA 4XSGB 4FK7A 1GIQA 4H0XA 4TR5A 4GF1A 2A78B 1OJQA 1PWUA 1J7NA 1OJZA 1GZFA 4H0VA 2J3VA 3U0JA 1QS2A 2C8BX 5DZQA 2BOVB 1GXYA 2WN5A 4PKWA 2J3ZA 2WN4A 4H03A 4XM8A 4PKRA 3BUZA 1OG1A 2C8HA 3BW8A 2A9KB 4ELNA 4WF6A 5D1TA
chains in the Genus database with same CATH superfamily
1R45A 2GWMA 1G24A 1GXZA 2C8FE 1QS1A 1PWPA 1R4BA 1JKYA 2C8DA 1GY0A 4GY2A 4PKVA 2WN6A 4PKUA 4PKSA 4PKQA 1PWQA 1ZXVA 1OG3A 4XSHB 4PKTA 4XM7A 1OG4A 4H0YA 5BWMB 1PWVA 1YQYA 1UZIA 2C8EE 4FMLA 3NTSA 2C8AA 4DV8A 4XM6A 4FXQA 4H0TA 2C89A 2C8GA 5H04A 2WN7A 2WN8A 5H03A 5D1UA 5GTTA 5D1SA 1GZEA 2GWLA 2J3XA 2C8CA 1PWWA 1GIRA 4XSGB 4FK7A 1GIQA 4H0XA 4TR5A 4GF1A 2A78B 1OJQA 1PWUA 1J7NA 1OJZA 1GZFA 4H0VA 2J3VA 3U0JA 1QS2A 2C8BX 5DZQA 2BOVB 1GXYA 2WN5A 4PKWA 2J3ZA 2WN4A 4H03A 4XM8A 4PKRA 3BUZA 1OG1A 2C8HA 3BW8A 2A9KB 4ELNA 4WF6A 5D1TA
chains in the Genus database with same CATH topology
1R45A 2GWMA 1G24A 1GXZA 2C8FE 1QS1A 1PWPA 1R4BA 1JKYA 2C8DA 1GY0A 4GY2A 4PKVA 2WN6A 4PKUA 4PKSA 4PKQA 1PWQA 1ZXVA 1OG3A 4XSHB 4PKTA 4XM7A 1OG4A 4H0YA 5BWMB 1PWVA 1YQYA 1UZIA 2C8EE 4FMLA 3NTSA 2C8AA 4DV8A 4XM6A 4FXQA 4H0TA 2C89A 2C8GA 5H04A 2WN7A 2WN8A 5H03A 5D1UA 5GTTA 5D1SA 1GZEA 2GWLA 2J3XA 2C8CA 1PWWA 1GIRA 4XSGB 4FK7A 1GIQA 4H0XA 4TR5A 4GF1A 2A78B 1OJQA 1PWUA 1J7NA 1OJZA 1GZFA 4H0VA 2J3VA 3U0JA 1QS2A 2C8BX 5DZQA 2BOVB 1GXYA 2WN5A 4PKWA 2J3ZA 2WN4A 4H03A 4XM8A 4PKRA 3BUZA 1OG1A 2C8HA 3BW8A 2A9KB 4ELNA 4WF6A 5D1TA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1R45 A;  2GWM A;  1G24 A;  1GXZ A;  2C8F E;  1QS1 A;  1PWP A;  1R4B A;  1JKY A;  2C8D A;  1GY0 A;  4GY2 A;  4PKV A;  2WN6 A;  4PKU A;  4PKS A;  4PKQ A;  1PWQ A;  1ZXV A;  1OG3 A;  4XSH B;  4PKT A;  4XM7 A;  1OG4 A;  4H0Y A;  5BWM B;  1PWV A;  1YQY A;  1UZI A;  2C8E E;  4FML A;  3NTS A;  2C8A A;  4DV8 A;  4XM6 A;  4FXQ A;  4H0T A;  2C89 A;  2C8G A;  5H04 A;  2WN7 A;  2WN8 A;  5H03 A;  5D1U A;  5GTT A;  5D1S A;  1GZE A;  2GWL A;  2J3X A;  2C8C A;  1PWW A;  1GIR A;  4XSG B;  4FK7 A;  1GIQ A;  4H0X A;  4TR5 A;  4GF1 A;  2A78 B;  1OJQ A;  1PWU A;  1J7N A;  1OJZ A;  1GZF A;  4H0V A;  2J3V A;  3U0J A;  1QS2 A;  2C8B X;  5DZQ A;  2BOV B;  1GXY A;  2WN5 A;  4PKW A;  2J3Z A;  2WN4 A;  4H03 A;  4XM8 A;  4PKR A;  3BUZ A;  1OG1 A;  2C8H A;  3BW8 A;  2A9K B;  4ELN A;  4WF6 A;  5D1T A; 
#chains in the Genus database with same CATH topology
 1R45 A;  2GWM A;  1G24 A;  1GXZ A;  2C8F E;  1QS1 A;  1PWP A;  1R4B A;  1JKY A;  2C8D A;  1GY0 A;  4GY2 A;  4PKV A;  2WN6 A;  4PKU A;  4PKS A;  4PKQ A;  1PWQ A;  1ZXV A;  1OG3 A;  4XSH B;  4PKT A;  4XM7 A;  1OG4 A;  4H0Y A;  5BWM B;  1PWV A;  1YQY A;  1UZI A;  2C8E E;  4FML A;  3NTS A;  2C8A A;  4DV8 A;  4XM6 A;  4FXQ A;  4H0T A;  2C89 A;  2C8G A;  5H04 A;  2WN7 A;  2WN8 A;  5H03 A;  5D1U A;  5GTT A;  5D1S A;  1GZE A;  2GWL A;  2J3X A;  2C8C A;  1PWW A;  1GIR A;  4XSG B;  4FK7 A;  1GIQ A;  4H0X A;  4TR5 A;  4GF1 A;  2A78 B;  1OJQ A;  1PWU A;  1J7N A;  1OJZ A;  1GZF A;  4H0V A;  2J3V A;  3U0J A;  1QS2 A;  2C8B X;  5DZQ A;  2BOV B;  1GXY A;  2WN5 A;  4PKW A;  2J3Z A;  2WN4 A;  4H03 A;  4XM8 A;  4PKR A;  3BUZ A;  1OG1 A;  2C8H A;  3BW8 A;  2A9K B;  4ELN A;  4WF6 A;  5D1T A; 
#chains in the Genus database with same CATH homology
 1R45 A;  2GWM A;  1G24 A;  1GXZ A;  2C8F E;  1QS1 A;  1PWP A;  1R4B A;  1JKY A;  2C8D A;  1GY0 A;  4GY2 A;  4PKV A;  2WN6 A;  4PKU A;  4PKS A;  4PKQ A;  1PWQ A;  1ZXV A;  1OG3 A;  4XSH B;  4PKT A;  4XM7 A;  1OG4 A;  4H0Y A;  5BWM B;  1PWV A;  1YQY A;  1UZI A;  2C8E E;  4FML A;  3NTS A;  2C8A A;  4DV8 A;  4XM6 A;  4FXQ A;  4H0T A;  2C89 A;  2C8G A;  5H04 A;  2WN7 A;  2WN8 A;  5H03 A;  5D1U A;  5GTT A;  5D1S A;  1GZE A;  2GWL A;  2J3X A;  2C8C A;  1PWW A;  1GIR A;  4XSG B;  4FK7 A;  1GIQ A;  4H0X A;  4TR5 A;  4GF1 A;  2A78 B;  1OJQ A;  1PWU A;  1J7N A;  1OJZ A;  1GZF A;  4H0V A;  2J3V A;  3U0J A;  1QS2 A;  2C8B X;  5DZQ A;  2BOV B;  1GXY A;  2WN5 A;  4PKW A;  2J3Z A;  2WN4 A;  4H03 A;  4XM8 A;  4PKR A;  3BUZ A;  1OG1 A;  2C8H A;  3BW8 A;  2A9K B;  4ELN A;  4WF6 A;  5D1T A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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