2IGPA

Crystal structure of hec1 ch domain
Total Genus 33
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
33
sequence length
114
structure length
114
Chain Sequence
DPRPLNDKAFIQQCIRQLCEFLTENGYAHNVSMKSLQAPSVKDFLKIFTFLYGFLCPSYELPDTKFEEEVPRIFKDLGYPFALSKSSMYTVGAPHTWPHIVAALVWLIDCIKIH
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title The Ndc80/HEC1 complex is a contact point for kinetochore-microtubule attachment.
pubmed doi rcsb
molecule tags Cell cycle
source organism Homo sapiens
molecule keywords Retinoblastoma-associated protein HEC
total genus 33
structure length 114
sequence length 114
ec nomenclature
pdb deposition date 2006-09-22
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.418.30 Mainly Alpha Orthogonal Bundle Actin-binding Protein, T-fimbrin; domain 1 Actin-binding Protein, T-fimbrin; domain 1 2igpA00
2IGPA 2VE7A
chains in the Genus database with same CATH superfamily
1VKAA 1BHDA 2DK9A 3KMWB 1WKUA 3JALM 3JAKM 2EE7A 1RT8A 3CO1A 2D87A 4TXIA 1DXXA 3HOCA 5A4BA 2VZCA 2WFNA 1H67A 3KY9A 3REPB 5L0OA 3JARM 4DDPA 2EYNA 1AA2A 4EDNA 2IGPA 1WYOA 5J8EA 1MB8A 2YRNA 1QAGA 2HL8A 1UJOA 1AOAA 1TJTA 1P2XA 4Q57B 4LVPA 5BVRA 5A36A 5FMTA 1PXYA 4Q58A 1P5SA 2R8UA 2VE7C 2WE6A 5A38A 1SH6A 1PA7A 5A37A 2WA7A 4EDMA 3F7PA 1WYMA 2QJXA 4EDLA 2HL9A 2WA5A 4Q59A 4LVRA 4B7LA 3HOPA 2D86A 2JV9A 2EQOA 1SH5A 2K3SA 1EUVA 3FERA 1UEGA 2D89A 3HORA 2VZDA 1WYQA 1BKRA 5FMUA 1V5KA 3VP7A 2K2RA 2RR8A 2QJZA 3I6XA 2D85A 2E9KA 1WYNA 2L3GA 1WJOA 2VE7A 2D88A 2WDTA 1WYLA 1WIXA 2HKPA 4TXKA 3EAYA 1WYPA 3KMUB 1WYRA 2R0OA 2VZIB 2VZGB 2WA6A 2EYIA
chains in the Genus database with same CATH topology
2IGPA 5FMTA 4DDPA 3VP7A 2VE7C 2HL9A 2WDTA 2WE6A 4LVRA 2HL8A 2HKPA 2VE7A 2EQOA 3EAYA 1EUVA 5FMUA 4LVPA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2IGP A;  2VE7 A; 
#chains in the Genus database with same CATH topology
 1VKA A;  1BHD A;  2DK9 A;  3KMW B;  1WKU A;  3JAL M;  3JAK M;  2EE7 A;  1RT8 A;  3CO1 A;  2D87 A;  4TXI A;  1DXX A;  3HOC A;  5A4B A;  2VZC A;  2WFN A;  1H67 A;  3KY9 A;  3REP B;  5L0O A;  3JAR M;  4DDP A;  2EYN A;  1AA2 A;  4EDN A;  2IGP A;  1WYO A;  5J8E A;  1MB8 A;  2YRN A;  1QAG A;  2HL8 A;  1UJO A;  1AOA A;  1TJT A;  1P2X A;  4Q57 B;  4LVP A;  5BVR A;  5A36 A;  5FMT A;  1PXY A;  4Q58 A;  1P5S A;  2R8U A;  2VE7 C;  2WE6 A;  5A38 A;  1SH6 A;  1PA7 A;  5A37 A;  2WA7 A;  4EDM A;  3F7P A;  1WYM A;  2QJX A;  4EDL A;  2HL9 A;  2WA5 A;  4Q59 A;  4LVR A;  4B7L A;  3HOP A;  2D86 A;  2JV9 A;  2EQO A;  1SH5 A;  2K3S A;  1EUV A;  3FER A;  1UEG A;  2D89 A;  3HOR A;  2VZD A;  1WYQ A;  1BKR A;  5FMU A;  1V5K A;  3VP7 A;  2K2R A;  2RR8 A;  2QJZ A;  3I6X A;  2D85 A;  2E9K A;  1WYN A;  2L3G A;  1WJO A;  2VE7 A;  2D88 A;  2WDT A;  1WYL A;  1WIX A;  2HKP A;  4TXK A;  3EAY A;  1WYP A;  3KMU B;  1WYR A;  2R0O A;  2VZI B;  2VZG B;  2WA6 A;  2EYI A; 
#chains in the Genus database with same CATH homology
 2IGP A;  5FMT A;  4DDP A;  3VP7 A;  2VE7 C;  2HL9 A;  2WDT A;  2WE6 A;  4LVR A;  2HL8 A;  2HKP A;  2VE7 A;  2EQO A;  3EAY A;  1EUV A;  5FMU A;  4LVP A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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