2J3XA

Crystal structure of the enzymatic component c2-i of the c2-toxin from clostridium botulinum at ph 3.0 (mut-s361r)
Total Genus 151
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
151
sequence length
430
structure length
430
Chain Sequence
PIIKEPIDFINKPESEAKEWGKEEEKRWFTKLNNLEEVAVNQLKNKEYKTKIDNFSTDILFSSLTAIEIMKEDENQNLFDVERIREALLKNTLDRDAIGYVNFTPKELGINFSIRDVELDRDISDETLDKVRQQIINQEYTKFSFISLGLNDNSINESVPVIVKTRVPTTFDYGVLNDKETVSLLLNQGFSIIPESAIITTIKGKDYILIEGSLSQELDFYNKGSEAWGAENYGDYISKLSHEQLGALEGYLHSDYKAINSYLRNNRVPNNDELNKKIELISSALSVKPIPQTLIAYRRVDGIPFDLPSDFSFDKKENGEIIADKQKLNEFIDKWTGKEIENLSFSSTSLKSTPSSFSKRRFIFRLRLSEGAIGAFIYGFSGFQDEQEILLNKNSTFKIFRITPITSIINRVTKMTQVVIDAEGIQNKEI
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structure and Action of the Binary C2 Toxin from Clostridium Botulinum.
pubmed doi rcsb
molecule tags Toxin
source organism Clostridium botulinum
molecule keywords C2 TOXIN COMPONENT I
total genus 151
structure length 430
sequence length 430
ec nomenclature
pdb deposition date 2006-08-23

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF03496 ADPrib_exo_Tox ADP-ribosyltransferase exoenzyme
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.176.10 Alpha Beta Alpha-Beta Complex Toxin ADP-ribosyltransferase; Chain A, domain 1 Toxin ADP-ribosyltransferase; Chain A, domain 1 2j3xA02
3.90.176.10 Alpha Beta Alpha-Beta Complex Toxin ADP-ribosyltransferase; Chain A, domain 1 Toxin ADP-ribosyltransferase; Chain A, domain 1 2j3xA01
1QS2A 1R4BA 4H0VA 1PWQA 1GZFA 3U0JA 4PKQA 1R45A 4PKRA 2WN8A 1OJZA 4DV8A 2WN5A 2J3ZA 1GY0A 1YQYA 3BUZA 2C8CA 5D1UA 4H03A 3BW8A 4TR5A 1ZXVA 2WN6A 2WN7A 4FK7A 1JKYA 4GF1A 4ELNA 2C8FE 4GY2A 4XSGB 4XM8A 4WF6A 2C8DA 2A9KB 4PKVA 5H03A 2C8AA 1GZEA 5H04A 5D1TA 4XSHB 2C8GA 2J3VA 1QS1A 1UZIA 2C8BX 1OG3A 1PWVA 2C8HA 1PWPA 1GIRA 2WN4A 2GWMA 4XM7A 1GIQA 4H0XA 4PKTA 1PWWA 4FMLA 2J3XA 2GWLA 2A78B 1PWUA 5DZQA 4PKUA 4PKSA 1OJQA 1OG4A 4H0YA 1G24A 4H0TA 2C89A 4XM6A 4PKWA 1GXYA 5BWMB 5GTTA 4FXQA 1GXZA 2C8EE 3NTSA 5D1SA 2BOVB 1J7NA 1OG1A
chains in the Genus database with same CATH superfamily
1QS2A 1R4BA 4H0VA 1PWQA 1GZFA 3U0JA 4PKQA 1R45A 4PKRA 2WN8A 1OJZA 4DV8A 2WN5A 2J3ZA 1GY0A 1YQYA 3BUZA 2C8CA 5D1UA 4H03A 3BW8A 4TR5A 1ZXVA 2WN6A 2WN7A 4FK7A 1JKYA 4GF1A 4ELNA 2C8FE 4GY2A 4XSGB 4XM8A 4WF6A 2C8DA 2A9KB 4PKVA 5H03A 2C8AA 1GZEA 5H04A 5D1TA 4XSHB 2C8GA 2J3VA 1QS1A 1UZIA 2C8BX 1OG3A 1PWVA 2C8HA 1PWPA 1GIRA 2WN4A 2GWMA 4XM7A 1GIQA 4H0XA 4PKTA 1PWWA 4FMLA 2J3XA 2GWLA 2A78B 1PWUA 5DZQA 4PKUA 4PKSA 1OJQA 1OG4A 4H0YA 1G24A 4H0TA 2C89A 4XM6A 4PKWA 1GXYA 5BWMB 5GTTA 4FXQA 1GXZA 2C8EE 3NTSA 5D1SA 2BOVB 1J7NA 1OG1A
chains in the Genus database with same CATH topology
1QS2A 1R4BA 4H0VA 1PWQA 1GZFA 3U0JA 4PKQA 1R45A 4PKRA 2WN8A 1OJZA 4DV8A 2WN5A 2J3ZA 1GY0A 1YQYA 3BUZA 2C8CA 5D1UA 4H03A 3BW8A 4TR5A 1ZXVA 2WN6A 2WN7A 4FK7A 1JKYA 4GF1A 4ELNA 2C8FE 4GY2A 4XSGB 4XM8A 4WF6A 2C8DA 2A9KB 4PKVA 5H03A 2C8AA 1GZEA 5H04A 5D1TA 4XSHB 2C8GA 2J3VA 1QS1A 1UZIA 2C8BX 1OG3A 1PWVA 2C8HA 1PWPA 1GIRA 2WN4A 2GWMA 4XM7A 1GIQA 4H0XA 4PKTA 1PWWA 4FMLA 2J3XA 2GWLA 2A78B 1PWUA 5DZQA 4PKUA 4PKSA 1OJQA 1OG4A 4H0YA 1G24A 4H0TA 2C89A 4XM6A 4PKWA 1GXYA 5BWMB 5GTTA 4FXQA 1GXZA 2C8EE 3NTSA 5D1SA 2BOVB 1J7NA 1OG1A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1QS2 A;  1R4B A;  4H0V A;  1PWQ A;  1GZF A;  3U0J A;  4PKQ A;  1R45 A;  4PKR A;  2WN8 A;  1OJZ A;  4DV8 A;  2WN5 A;  2J3Z A;  1GY0 A;  1YQY A;  3BUZ A;  2C8C A;  5D1U A;  4H03 A;  3BW8 A;  4TR5 A;  1ZXV A;  2WN6 A;  2WN7 A;  4FK7 A;  1JKY A;  4GF1 A;  4ELN A;  2C8F E;  4GY2 A;  4XSG B;  4XM8 A;  4WF6 A;  2C8D A;  2A9K B;  4PKV A;  5H03 A;  2C8A A;  1GZE A;  5H04 A;  5D1T A;  4XSH B;  2C8G A;  2J3V A;  1QS1 A;  1UZI A;  2C8B X;  1OG3 A;  1PWV A;  2C8H A;  1PWP A;  1GIR A;  2WN4 A;  2GWM A;  4XM7 A;  1GIQ A;  4H0X A;  4PKT A;  1PWW A;  4FML A;  2J3X A;  2GWL A;  2A78 B;  1PWU A;  5DZQ A;  4PKU A;  4PKS A;  1OJQ A;  1OG4 A;  4H0Y A;  1G24 A;  4H0T A;  2C89 A;  4XM6 A;  4PKW A;  1GXY A;  5BWM B;  5GTT A;  4FXQ A;  1GXZ A;  2C8E E;  3NTS A;  5D1S A;  2BOV B;  1J7N A;  1OG1 A; 
#chains in the Genus database with same CATH topology
 1QS2 A;  1R4B A;  4H0V A;  1PWQ A;  1GZF A;  3U0J A;  4PKQ A;  1R45 A;  4PKR A;  2WN8 A;  1OJZ A;  4DV8 A;  2WN5 A;  2J3Z A;  1GY0 A;  1YQY A;  3BUZ A;  2C8C A;  5D1U A;  4H03 A;  3BW8 A;  4TR5 A;  1ZXV A;  2WN6 A;  2WN7 A;  4FK7 A;  1JKY A;  4GF1 A;  4ELN A;  2C8F E;  4GY2 A;  4XSG B;  4XM8 A;  4WF6 A;  2C8D A;  2A9K B;  4PKV A;  5H03 A;  2C8A A;  1GZE A;  5H04 A;  5D1T A;  4XSH B;  2C8G A;  2J3V A;  1QS1 A;  1UZI A;  2C8B X;  1OG3 A;  1PWV A;  2C8H A;  1PWP A;  1GIR A;  2WN4 A;  2GWM A;  4XM7 A;  1GIQ A;  4H0X A;  4PKT A;  1PWW A;  4FML A;  2J3X A;  2GWL A;  2A78 B;  1PWU A;  5DZQ A;  4PKU A;  4PKS A;  1OJQ A;  1OG4 A;  4H0Y A;  1G24 A;  4H0T A;  2C89 A;  4XM6 A;  4PKW A;  1GXY A;  5BWM B;  5GTT A;  4FXQ A;  1GXZ A;  2C8E E;  3NTS A;  5D1S A;  2BOV B;  1J7N A;  1OG1 A; 
#chains in the Genus database with same CATH homology
 1QS2 A;  1R4B A;  4H0V A;  1PWQ A;  1GZF A;  3U0J A;  4PKQ A;  1R45 A;  4PKR A;  2WN8 A;  1OJZ A;  4DV8 A;  2WN5 A;  2J3Z A;  1GY0 A;  1YQY A;  3BUZ A;  2C8C A;  5D1U A;  4H03 A;  3BW8 A;  4TR5 A;  1ZXV A;  2WN6 A;  2WN7 A;  4FK7 A;  1JKY A;  4GF1 A;  4ELN A;  2C8F E;  4GY2 A;  4XSG B;  4XM8 A;  4WF6 A;  2C8D A;  2A9K B;  4PKV A;  5H03 A;  2C8A A;  1GZE A;  5H04 A;  5D1T A;  4XSH B;  2C8G A;  2J3V A;  1QS1 A;  1UZI A;  2C8B X;  1OG3 A;  1PWV A;  2C8H A;  1PWP A;  1GIR A;  2WN4 A;  2GWM A;  4XM7 A;  1GIQ A;  4H0X A;  4PKT A;  1PWW A;  4FML A;  2J3X A;  2GWL A;  2A78 B;  1PWU A;  5DZQ A;  4PKU A;  4PKS A;  1OJQ A;  1OG4 A;  4H0Y A;  1G24 A;  4H0T A;  2C89 A;  4XM6 A;  4PKW A;  1GXY A;  5BWM B;  5GTT A;  4FXQ A;  1GXZ A;  2C8E E;  3NTS A;  5D1S A;  2BOV B;  1J7N A;  1OG1 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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