2K3SA

Haddock-derived structure of the ch-domain of the smoothelin-like 1 complexed with the c-domain of apocalmodulin
Total Genus 39
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
39
sequence length
119
structure length
119
Chain Sequence
GPLGSKNMLLEWCRAMTRNYEHVDIQNFSSSWSSGMAFCALIHKFFPEAFDYAELDPAKRRHNFTLAFSTAEKLADCAQLLEVDDMVRLAVPDSKCVYTYIQELYRSLVQKGLVKTKKK
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Protein binding
source organism Mus musculus
publication title Solution structure of the calponin homology (CH) domain from the smoothelin-like 1 protein: a unique apocalmodulin-binding mode and the possible role of the C-terminal type-2 CH-domain in smooth muscle relaxation.
pubmed doi rcsb
molecule keywords Smoothelin-like protein 1
total genus 39
structure length 119
sequence length 119
ec nomenclature
pdb deposition date 2008-05-15
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.418.10 Mainly Alpha Orthogonal Bundle Actin-binding Protein, T-fimbrin; domain 1 Calponin-like domain 2k3sA01
3KMWB 4Q58A 1MB8A 3KY9A 2QJZA 3JARM 1BKRA 5J8EA 5A36A 1VKAA 2EYNA 1RT8A 4TXKA 2K3SA 2D89A 1WYQA 2WA7A 1PA7A 1DXXA 1P5SA 2DK9A 2VZIB 1WYRA 1WYLA 3KMUB 5BVRA 3I6XA 1WYMA 5A4BA 2R8UA 2R0OA 1TJTA 3HOPA 1WJOA 3CO1A 5L0OA 4B7LA 1P2XA 1SH5A 2YRNA 3REPB 1WIXA 5A38A 2D87A 1PXYA 1WKUA 1WYOA 3JALM 4Q59A 2D88A 2EE7A 2E9KA 5A37A 4EDLA 2RR8A 4Q57B 1V5KA 4TXIA 2JV9A 2WA5A 1WYPA 2VZGB 3F7PA 3HOCA 1UEGA 2D85A 1AA2A 3FERA 1AOAA 3JAKM 1WYNA 1BHDA 2K2RA 2WA6A 1H67A 2WFNA 3HORA 1UJOA 2VZDA 2EYIA 4EDMA 2D86A 2QJXA 2L3GA 1QAGA 4EDNA 2VZCA 1SH6A
chains in the Genus database with same CATH superfamily
3KMWB 4Q58A 1MB8A 3KY9A 2QJZA 3JARM 1BKRA 5J8EA 5FMTA 5A36A 1VKAA 2EYNA 1RT8A 4TXKA 2K3SA 2D89A 1WYQA 2WA7A 1PA7A 1DXXA 1P5SA 2DK9A 2VZIB 1WYRA 1WYLA 3KMUB 5BVRA 2HKPA 3I6XA 1WYMA 5A4BA 2R8UA 2R0OA 1TJTA 3HOPA 1WJOA 3CO1A 3VP7A 5L0OA 2HL9A 4B7LA 1P2XA 4LVPA 1SH5A 2YRNA 3REPB 1WIXA 5A38A 2D87A 1PXYA 1WKUA 1WYOA 3JALM 4Q59A 2D88A 2EE7A 2E9KA 5A37A 2VE7A 5FMUA 4EDLA 2RR8A 4Q57B 1V5KA 4TXIA 2JV9A 2WA5A 3EAYA 1WYPA 2VZGB 3F7PA 2HL8A 3HOCA 1UEGA 2D85A 2WE6A 2VE7C 1AA2A 3FERA 1AOAA 2EQOA 3JAKM 4DDPA 1WYNA 1EUVA 1BHDA 2K2RA 2WA6A 1H67A 2WFNA 3HORA 1UJOA 2VZDA 2EYIA 4EDMA 2D86A 2QJXA 2WDTA 2L3GA 1QAGA 4EDNA 4LVRA 2VZCA 1SH6A 2IGPA
chains in the Genus database with same CATH topology
3KMWB 4Q58A 1MB8A 3KY9A 2QJZA 3JARM 1BKRA 5J8EA 5A36A 1VKAA 2EYNA 1RT8A 4TXKA 2K3SA 2D89A 1WYQA 2WA7A 1PA7A 1DXXA 1P5SA 2DK9A 2VZIB 1WYRA 1WYLA 3KMUB 5BVRA 3I6XA 1WYMA 5A4BA 2R8UA 2R0OA 1TJTA 3HOPA 1WJOA 3CO1A 5L0OA 4B7LA 1P2XA 1SH5A 2YRNA 3REPB 1WIXA 5A38A 2D87A 1PXYA 1WKUA 1WYOA 3JALM 4Q59A 2D88A 2EE7A 2E9KA 5A37A 4EDLA 2RR8A 4Q57B 1V5KA 4TXIA 2JV9A 2WA5A 1WYPA 2VZGB 3F7PA 3HOCA 1UEGA 2D85A 1AA2A 3FERA 1AOAA 3JAKM 1WYNA 1BHDA 2K2RA 2WA6A 1H67A 2WFNA 3HORA 1UJOA 2VZDA 2EYIA 4EDMA 2D86A 2QJXA 2L3GA 1QAGA 4EDNA 2VZCA 1SH6A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3KMW B;  4Q58 A;  1MB8 A;  3KY9 A;  2QJZ A;  3JAR M;  1BKR A;  5J8E A;  5A36 A;  1VKA A;  2EYN A;  1RT8 A;  4TXK A;  2K3S A;  2D89 A;  1WYQ A;  2WA7 A;  1PA7 A;  1DXX A;  1P5S A;  2DK9 A;  2VZI B;  1WYR A;  1WYL A;  3KMU B;  5BVR A;  3I6X A;  1WYM A;  5A4B A;  2R8U A;  2R0O A;  1TJT A;  3HOP A;  1WJO A;  3CO1 A;  5L0O A;  4B7L A;  1P2X A;  1SH5 A;  2YRN A;  3REP B;  1WIX A;  5A38 A;  2D87 A;  1PXY A;  1WKU A;  1WYO A;  3JAL M;  4Q59 A;  2D88 A;  2EE7 A;  2E9K A;  5A37 A;  4EDL A;  2RR8 A;  4Q57 B;  1V5K A;  4TXI A;  2JV9 A;  2WA5 A;  1WYP A;  2VZG B;  3F7P A;  3HOC A;  1UEG A;  2D85 A;  1AA2 A;  3FER A;  1AOA A;  3JAK M;  1WYN A;  1BHD A;  2K2R A;  2WA6 A;  1H67 A;  2WFN A;  3HOR A;  1UJO A;  2VZD A;  2EYI A;  4EDM A;  2D86 A;  2QJX A;  2L3G A;  1QAG A;  4EDN A;  2VZC A;  1SH6 A; 
#chains in the Genus database with same CATH topology
 3KMW B;  4Q58 A;  1MB8 A;  3KY9 A;  2QJZ A;  3JAR M;  1BKR A;  5J8E A;  5FMT A;  5A36 A;  1VKA A;  2EYN A;  1RT8 A;  4TXK A;  2K3S A;  2D89 A;  1WYQ A;  2WA7 A;  1PA7 A;  1DXX A;  1P5S A;  2DK9 A;  2VZI B;  1WYR A;  1WYL A;  3KMU B;  5BVR A;  2HKP A;  3I6X A;  1WYM A;  5A4B A;  2R8U A;  2R0O A;  1TJT A;  3HOP A;  1WJO A;  3CO1 A;  3VP7 A;  5L0O A;  2HL9 A;  4B7L A;  1P2X A;  4LVP A;  1SH5 A;  2YRN A;  3REP B;  1WIX A;  5A38 A;  2D87 A;  1PXY A;  1WKU A;  1WYO A;  3JAL M;  4Q59 A;  2D88 A;  2EE7 A;  2E9K A;  5A37 A;  2VE7 A;  5FMU A;  4EDL A;  2RR8 A;  4Q57 B;  1V5K A;  4TXI A;  2JV9 A;  2WA5 A;  3EAY A;  1WYP A;  2VZG B;  3F7P A;  2HL8 A;  3HOC A;  1UEG A;  2D85 A;  2WE6 A;  2VE7 C;  1AA2 A;  3FER A;  1AOA A;  2EQO A;  3JAK M;  4DDP A;  1WYN A;  1EUV A;  1BHD A;  2K2R A;  2WA6 A;  1H67 A;  2WFN A;  3HOR A;  1UJO A;  2VZD A;  2EYI A;  4EDM A;  2D86 A;  2QJX A;  2WDT A;  2L3G A;  1QAG A;  4EDN A;  4LVR A;  2VZC A;  1SH6 A;  2IGP A; 
#chains in the Genus database with same CATH homology
 3KMW B;  4Q58 A;  1MB8 A;  3KY9 A;  2QJZ A;  3JAR M;  1BKR A;  5J8E A;  5A36 A;  1VKA A;  2EYN A;  1RT8 A;  4TXK A;  2K3S A;  2D89 A;  1WYQ A;  2WA7 A;  1PA7 A;  1DXX A;  1P5S A;  2DK9 A;  2VZI B;  1WYR A;  1WYL A;  3KMU B;  5BVR A;  3I6X A;  1WYM A;  5A4B A;  2R8U A;  2R0O A;  1TJT A;  3HOP A;  1WJO A;  3CO1 A;  5L0O A;  4B7L A;  1P2X A;  1SH5 A;  2YRN A;  3REP B;  1WIX A;  5A38 A;  2D87 A;  1PXY A;  1WKU A;  1WYO A;  3JAL M;  4Q59 A;  2D88 A;  2EE7 A;  2E9K A;  5A37 A;  4EDL A;  2RR8 A;  4Q57 B;  1V5K A;  4TXI A;  2JV9 A;  2WA5 A;  1WYP A;  2VZG B;  3F7P A;  3HOC A;  1UEG A;  2D85 A;  1AA2 A;  3FER A;  1AOA A;  3JAK M;  1WYN A;  1BHD A;  2K2R A;  2WA6 A;  1H67 A;  2WFN A;  3HOR A;  1UJO A;  2VZD A;  2EYI A;  4EDM A;  2D86 A;  2QJX A;  2L3G A;  1QAG A;  4EDN A;  2VZC A;  1SH6 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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