2K3SA

Haddock-derived structure of the ch-domain of the smoothelin-like 1 complexed with the c-domain of apocalmodulin
Total Genus 39
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
39
sequence length
119
structure length
119
Chain Sequence
GPLGSKNMLLEWCRAMTRNYEHVDIQNFSSSWSSGMAFCALIHKFFPEAFDYAELDPAKRRHNFTLAFSTAEKLADCAQLLEVDDMVRLAVPDSKCVYTYIQELYRSLVQKGLVKTKKK
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Solution structure of the calponin homology (CH) domain from the smoothelin-like 1 protein: a unique apocalmodulin-binding mode and the possible role of the C-terminal type-2 CH-domain in smooth muscle relaxation.
pubmed doi rcsb
molecule tags Protein binding
source organism Mus musculus
molecule keywords Smoothelin-like protein 1
total genus 39
structure length 119
sequence length 119
ec nomenclature
pdb deposition date 2008-05-15
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.418.10 Mainly Alpha Orthogonal Bundle Actin-binding Protein, T-fimbrin; domain 1 Calponin-like domain 2k3sA01
2EYIA 4EDLA 1V5KA 2R0OA 2VZGB 4EDMA 2DK9A 4TXIA 3KMWB 3JARM 2WA5A 3HOCA 1WYMA 2R8UA 2K2RA 5BVRA 2WA6A 3KMUB 4Q57B 1PXYA 1RT8A 2QJZA 1PA7A 3FERA 2EE7A 3REPB 1BKRA 2K3SA 3F7PA 3JAKM 2QJXA 5J8EA 3HORA 1SH6A 1WYNA 1UJOA 2JV9A 2VZDA 2VZCA 5A38A 1SH5A 1UEGA 1VKAA 3HOPA 5A37A 2D89A 1BHDA 1QAGA 2EYNA 3KY9A 5A36A 1MB8A 1WIXA 1AOAA 2VZIB 2WA7A 3JALM 4EDNA 3I6XA 2D86A 2D85A 4Q58A 1WYPA 3CO1A 1H67A 2L3GA 2YRNA 1WYOA 1WJOA 1WYRA 2WFNA 1WYLA 5A4BA 4B7LA 1P2XA 4TXKA 2RR8A 2E9KA 1TJTA 2D87A 5L0OA 1AA2A 4Q59A 1DXXA 1WYQA 2D88A 1P5SA 1WKUA
chains in the Genus database with same CATH superfamily
2EYIA 4LVPA 4EDLA 1V5KA 2R0OA 2VZGB 4EDMA 1EUVA 3VP7A 2DK9A 4TXIA 5FMUA 3KMWB 3JARM 5FMTA 2WA5A 3EAYA 3HOCA 2HKPA 1WYMA 2R8UA 2IGPA 2K2RA 5BVRA 2WE6A 2WA6A 3KMUB 4Q57B 1PXYA 1RT8A 2QJZA 1PA7A 3FERA 2EE7A 3REPB 1BKRA 2K3SA 2VE7A 3F7PA 4LVRA 3JAKM 2QJXA 5J8EA 3HORA 1SH6A 1WYNA 2HL8A 1UJOA 2JV9A 2VZDA 2VZCA 5A38A 1SH5A 1UEGA 1VKAA 3HOPA 5A37A 2D89A 1BHDA 1QAGA 2EYNA 3KY9A 5A36A 1MB8A 1WIXA 1AOAA 2VZIB 2WA7A 3JALM 4EDNA 3I6XA 2D86A 2D85A 4Q58A 2VE7C 2WDTA 1WYPA 3CO1A 1H67A 2L3GA 2YRNA 4DDPA 1WYOA 1WJOA 1WYRA 2WFNA 1WYLA 2EQOA 5A4BA 4B7LA 1P2XA 4TXKA 2RR8A 2E9KA 1TJTA 2HL9A 2D87A 5L0OA 1AA2A 4Q59A 1DXXA 1WYQA 2D88A 1P5SA 1WKUA
chains in the Genus database with same CATH topology
2EYIA 4EDLA 1V5KA 2R0OA 2VZGB 4EDMA 2DK9A 4TXIA 3KMWB 3JARM 2WA5A 3HOCA 1WYMA 2R8UA 2K2RA 5BVRA 2WA6A 3KMUB 4Q57B 1PXYA 1RT8A 2QJZA 1PA7A 3FERA 2EE7A 3REPB 1BKRA 2K3SA 3F7PA 3JAKM 2QJXA 5J8EA 3HORA 1SH6A 1WYNA 1UJOA 2JV9A 2VZDA 2VZCA 5A38A 1SH5A 1UEGA 1VKAA 3HOPA 5A37A 2D89A 1BHDA 1QAGA 2EYNA 3KY9A 5A36A 1MB8A 1WIXA 1AOAA 2VZIB 2WA7A 3JALM 4EDNA 3I6XA 2D86A 2D85A 4Q58A 1WYPA 3CO1A 1H67A 2L3GA 2YRNA 1WYOA 1WJOA 1WYRA 2WFNA 1WYLA 5A4BA 4B7LA 1P2XA 4TXKA 2RR8A 2E9KA 1TJTA 2D87A 5L0OA 1AA2A 4Q59A 1DXXA 1WYQA 2D88A 1P5SA 1WKUA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2EYI A;  4EDL A;  1V5K A;  2R0O A;  2VZG B;  4EDM A;  2DK9 A;  4TXI A;  3KMW B;  3JAR M;  2WA5 A;  3HOC A;  1WYM A;  2R8U A;  2K2R A;  5BVR A;  2WA6 A;  3KMU B;  4Q57 B;  1PXY A;  1RT8 A;  2QJZ A;  1PA7 A;  3FER A;  2EE7 A;  3REP B;  1BKR A;  2K3S A;  3F7P A;  3JAK M;  2QJX A;  5J8E A;  3HOR A;  1SH6 A;  1WYN A;  1UJO A;  2JV9 A;  2VZD A;  2VZC A;  5A38 A;  1SH5 A;  1UEG A;  1VKA A;  3HOP A;  5A37 A;  2D89 A;  1BHD A;  1QAG A;  2EYN A;  3KY9 A;  5A36 A;  1MB8 A;  1WIX A;  1AOA A;  2VZI B;  2WA7 A;  3JAL M;  4EDN A;  3I6X A;  2D86 A;  2D85 A;  4Q58 A;  1WYP A;  3CO1 A;  1H67 A;  2L3G A;  2YRN A;  1WYO A;  1WJO A;  1WYR A;  2WFN A;  1WYL A;  5A4B A;  4B7L A;  1P2X A;  4TXK A;  2RR8 A;  2E9K A;  1TJT A;  2D87 A;  5L0O A;  1AA2 A;  4Q59 A;  1DXX A;  1WYQ A;  2D88 A;  1P5S A;  1WKU A; 
#chains in the Genus database with same CATH topology
 2EYI A;  4LVP A;  4EDL A;  1V5K A;  2R0O A;  2VZG B;  4EDM A;  1EUV A;  3VP7 A;  2DK9 A;  4TXI A;  5FMU A;  3KMW B;  3JAR M;  5FMT A;  2WA5 A;  3EAY A;  3HOC A;  2HKP A;  1WYM A;  2R8U A;  2IGP A;  2K2R A;  5BVR A;  2WE6 A;  2WA6 A;  3KMU B;  4Q57 B;  1PXY A;  1RT8 A;  2QJZ A;  1PA7 A;  3FER A;  2EE7 A;  3REP B;  1BKR A;  2K3S A;  2VE7 A;  3F7P A;  4LVR A;  3JAK M;  2QJX A;  5J8E A;  3HOR A;  1SH6 A;  1WYN A;  2HL8 A;  1UJO A;  2JV9 A;  2VZD A;  2VZC A;  5A38 A;  1SH5 A;  1UEG A;  1VKA A;  3HOP A;  5A37 A;  2D89 A;  1BHD A;  1QAG A;  2EYN A;  3KY9 A;  5A36 A;  1MB8 A;  1WIX A;  1AOA A;  2VZI B;  2WA7 A;  3JAL M;  4EDN A;  3I6X A;  2D86 A;  2D85 A;  4Q58 A;  2VE7 C;  2WDT A;  1WYP A;  3CO1 A;  1H67 A;  2L3G A;  2YRN A;  4DDP A;  1WYO A;  1WJO A;  1WYR A;  2WFN A;  1WYL A;  2EQO A;  5A4B A;  4B7L A;  1P2X A;  4TXK A;  2RR8 A;  2E9K A;  1TJT A;  2HL9 A;  2D87 A;  5L0O A;  1AA2 A;  4Q59 A;  1DXX A;  1WYQ A;  2D88 A;  1P5S A;  1WKU A; 
#chains in the Genus database with same CATH homology
 2EYI A;  4EDL A;  1V5K A;  2R0O A;  2VZG B;  4EDM A;  2DK9 A;  4TXI A;  3KMW B;  3JAR M;  2WA5 A;  3HOC A;  1WYM A;  2R8U A;  2K2R A;  5BVR A;  2WA6 A;  3KMU B;  4Q57 B;  1PXY A;  1RT8 A;  2QJZ A;  1PA7 A;  3FER A;  2EE7 A;  3REP B;  1BKR A;  2K3S A;  3F7P A;  3JAK M;  2QJX A;  5J8E A;  3HOR A;  1SH6 A;  1WYN A;  1UJO A;  2JV9 A;  2VZD A;  2VZC A;  5A38 A;  1SH5 A;  1UEG A;  1VKA A;  3HOP A;  5A37 A;  2D89 A;  1BHD A;  1QAG A;  2EYN A;  3KY9 A;  5A36 A;  1MB8 A;  1WIX A;  1AOA A;  2VZI B;  2WA7 A;  3JAL M;  4EDN A;  3I6X A;  2D86 A;  2D85 A;  4Q58 A;  1WYP A;  3CO1 A;  1H67 A;  2L3G A;  2YRN A;  1WYO A;  1WJO A;  1WYR A;  2WFN A;  1WYL A;  5A4B A;  4B7L A;  1P2X A;  4TXK A;  2RR8 A;  2E9K A;  1TJT A;  2D87 A;  5L0O A;  1AA2 A;  4Q59 A;  1DXX A;  1WYQ A;  2D88 A;  1P5S A;  1WKU A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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