2L3GA

Solution nmr structure of ch domain of rho guanine nucleotide exchange factor 7 from homo sapiens, northeast structural genomics consortium target hr4495e
Total Genus 35
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
35
sequence length
126
structure length
126
Chain Sequence
MGHHHHHHSHMNSAEQTVTWLITLGVLESPKKTISDPEGFLQASLKDGVVLCRLLERLLPGTIEKVYPEPRSESECLSNIREFLRGCGASLRLETFDANDLYQGQNFNKVLSSLVTLNKVTADIGL
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Northeast Structural Genomics Consortium Target HR4495E
rcsb
molecule tags Signaling protein
source organism Homo sapiens
molecule keywords Rho guanine nucleotide exchange factor 7
total genus 35
structure length 126
sequence length 126
ec nomenclature
pdb deposition date 2010-09-13
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.418.10 Mainly Alpha Orthogonal Bundle Actin-binding Protein, T-fimbrin; domain 1 Calponin-like domain 2l3gA00
1BKRA 1WYMA 3FERA 5J8EA 1WKUA 1WIXA 2DK9A 2RR8A 3KMWB 1RT8A 3HOCA 5A36A 4EDLA 2EYIA 2EYNA 3JALM 5A4BA 2QJZA 1WYPA 1P5SA 3HORA 1VKAA 4B7LA 1DXXA 2L3GA 1H67A 2EE7A 4Q57B 1AOAA 1UJOA 2D89A 4EDNA 1AA2A 1WYRA 2VZDA 3KMUB 2K2RA 2D87A 3HOPA 2R8UA 5A38A 2JV9A 1PXYA 2K3SA 3JAKM 4Q58A 1P2XA 1TJTA 5BVRA 2R0OA 1QAGA 1WYLA 2VZIB 2WFNA 2VZGB 3I6XA 2E9KA 4TXKA 2WA7A 2D88A 5A37A 1V5KA 4EDMA 1SH6A 3JARM 2D86A 1WJOA 1UEGA 2YRNA 3CO1A 5L0OA 4TXIA 3KY9A 2VZCA 2WA6A 3REPB 1WYQA 1BHDA 1PA7A 1WYOA 2D85A 2WA5A 4Q59A 1SH5A 1MB8A 3F7PA 2QJXA 1WYNA
chains in the Genus database with same CATH superfamily
5FMTA 1BKRA 1WYMA 3FERA 5J8EA 1WKUA 1WIXA 2DK9A 4LVRA 2RR8A 3KMWB 1RT8A 3HOCA 5A36A 1EUVA 4EDLA 2EYIA 2EYNA 3JALM 5A4BA 2QJZA 1WYPA 1P5SA 3HORA 1VKAA 4B7LA 1DXXA 2HL9A 2L3GA 1H67A 2EE7A 4Q57B 1AOAA 1UJOA 2D89A 4EDNA 1AA2A 1WYRA 2VZDA 3KMUB 2K2RA 2D87A 3HOPA 2HL8A 2R8UA 5A38A 2JV9A 1PXYA 2K3SA 3JAKM 2VE7A 3EAYA 4Q58A 2EQOA 1P2XA 1TJTA 2IGPA 5BVRA 5FMUA 2R0OA 1QAGA 1WYLA 2VZIB 2WFNA 2VZGB 3I6XA 2E9KA 4TXKA 2WE6A 2WA7A 2D88A 5A37A 1V5KA 4LVPA 4EDMA 1SH6A 3JARM 2D86A 1WJOA 1UEGA 2WDTA 2YRNA 3CO1A 5L0OA 4TXIA 3KY9A 2VZCA 2WA6A 3REPB 1WYQA 3VP7A 1BHDA 4DDPA 1PA7A 1WYOA 2D85A 2WA5A 4Q59A 1SH5A 2VE7C 1MB8A 2HKPA 3F7PA 2QJXA 1WYNA
chains in the Genus database with same CATH topology
1BKRA 1WYMA 3FERA 5J8EA 1WKUA 1WIXA 2DK9A 2RR8A 3KMWB 1RT8A 3HOCA 5A36A 4EDLA 2EYIA 2EYNA 3JALM 5A4BA 2QJZA 1WYPA 1P5SA 3HORA 1VKAA 4B7LA 1DXXA 2L3GA 1H67A 2EE7A 4Q57B 1AOAA 1UJOA 2D89A 4EDNA 1AA2A 1WYRA 2VZDA 3KMUB 2K2RA 2D87A 3HOPA 2R8UA 5A38A 2JV9A 1PXYA 2K3SA 3JAKM 4Q58A 1P2XA 1TJTA 5BVRA 2R0OA 1QAGA 1WYLA 2VZIB 2WFNA 2VZGB 3I6XA 2E9KA 4TXKA 2WA7A 2D88A 5A37A 1V5KA 4EDMA 1SH6A 3JARM 2D86A 1WJOA 1UEGA 2YRNA 3CO1A 5L0OA 4TXIA 3KY9A 2VZCA 2WA6A 3REPB 1WYQA 1BHDA 1PA7A 1WYOA 2D85A 2WA5A 4Q59A 1SH5A 1MB8A 3F7PA 2QJXA 1WYNA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1BKR A;  1WYM A;  3FER A;  5J8E A;  1WKU A;  1WIX A;  2DK9 A;  2RR8 A;  3KMW B;  1RT8 A;  3HOC A;  5A36 A;  4EDL A;  2EYI A;  2EYN A;  3JAL M;  5A4B A;  2QJZ A;  1WYP A;  1P5S A;  3HOR A;  1VKA A;  4B7L A;  1DXX A;  2L3G A;  1H67 A;  2EE7 A;  4Q57 B;  1AOA A;  1UJO A;  2D89 A;  4EDN A;  1AA2 A;  1WYR A;  2VZD A;  3KMU B;  2K2R A;  2D87 A;  3HOP A;  2R8U A;  5A38 A;  2JV9 A;  1PXY A;  2K3S A;  3JAK M;  4Q58 A;  1P2X A;  1TJT A;  5BVR A;  2R0O A;  1QAG A;  1WYL A;  2VZI B;  2WFN A;  2VZG B;  3I6X A;  2E9K A;  4TXK A;  2WA7 A;  2D88 A;  5A37 A;  1V5K A;  4EDM A;  1SH6 A;  3JAR M;  2D86 A;  1WJO A;  1UEG A;  2YRN A;  3CO1 A;  5L0O A;  4TXI A;  3KY9 A;  2VZC A;  2WA6 A;  3REP B;  1WYQ A;  1BHD A;  1PA7 A;  1WYO A;  2D85 A;  2WA5 A;  4Q59 A;  1SH5 A;  1MB8 A;  3F7P A;  2QJX A;  1WYN A; 
#chains in the Genus database with same CATH topology
 5FMT A;  1BKR A;  1WYM A;  3FER A;  5J8E A;  1WKU A;  1WIX A;  2DK9 A;  4LVR A;  2RR8 A;  3KMW B;  1RT8 A;  3HOC A;  5A36 A;  1EUV A;  4EDL A;  2EYI A;  2EYN A;  3JAL M;  5A4B A;  2QJZ A;  1WYP A;  1P5S A;  3HOR A;  1VKA A;  4B7L A;  1DXX A;  2HL9 A;  2L3G A;  1H67 A;  2EE7 A;  4Q57 B;  1AOA A;  1UJO A;  2D89 A;  4EDN A;  1AA2 A;  1WYR A;  2VZD A;  3KMU B;  2K2R A;  2D87 A;  3HOP A;  2HL8 A;  2R8U A;  5A38 A;  2JV9 A;  1PXY A;  2K3S A;  3JAK M;  2VE7 A;  3EAY A;  4Q58 A;  2EQO A;  1P2X A;  1TJT A;  2IGP A;  5BVR A;  5FMU A;  2R0O A;  1QAG A;  1WYL A;  2VZI B;  2WFN A;  2VZG B;  3I6X A;  2E9K A;  4TXK A;  2WE6 A;  2WA7 A;  2D88 A;  5A37 A;  1V5K A;  4LVP A;  4EDM A;  1SH6 A;  3JAR M;  2D86 A;  1WJO A;  1UEG A;  2WDT A;  2YRN A;  3CO1 A;  5L0O A;  4TXI A;  3KY9 A;  2VZC A;  2WA6 A;  3REP B;  1WYQ A;  3VP7 A;  1BHD A;  4DDP A;  1PA7 A;  1WYO A;  2D85 A;  2WA5 A;  4Q59 A;  1SH5 A;  2VE7 C;  1MB8 A;  2HKP A;  3F7P A;  2QJX A;  1WYN A; 
#chains in the Genus database with same CATH homology
 1BKR A;  1WYM A;  3FER A;  5J8E A;  1WKU A;  1WIX A;  2DK9 A;  2RR8 A;  3KMW B;  1RT8 A;  3HOC A;  5A36 A;  4EDL A;  2EYI A;  2EYN A;  3JAL M;  5A4B A;  2QJZ A;  1WYP A;  1P5S A;  3HOR A;  1VKA A;  4B7L A;  1DXX A;  2L3G A;  1H67 A;  2EE7 A;  4Q57 B;  1AOA A;  1UJO A;  2D89 A;  4EDN A;  1AA2 A;  1WYR A;  2VZD A;  3KMU B;  2K2R A;  2D87 A;  3HOP A;  2R8U A;  5A38 A;  2JV9 A;  1PXY A;  2K3S A;  3JAK M;  4Q58 A;  1P2X A;  1TJT A;  5BVR A;  2R0O A;  1QAG A;  1WYL A;  2VZI B;  2WFN A;  2VZG B;  3I6X A;  2E9K A;  4TXK A;  2WA7 A;  2D88 A;  5A37 A;  1V5K A;  4EDM A;  1SH6 A;  3JAR M;  2D86 A;  1WJO A;  1UEG A;  2YRN A;  3CO1 A;  5L0O A;  4TXI A;  3KY9 A;  2VZC A;  2WA6 A;  3REP B;  1WYQ A;  1BHD A;  1PA7 A;  1WYO A;  2D85 A;  2WA5 A;  4Q59 A;  1SH5 A;  1MB8 A;  3F7P A;  2QJX A;  1WYN A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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