2VE7A

Crystal structure of a bonsai version of the human ndc80 complex
Total Genus 62
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
62
sequence length
312
structure length
246
Chain Sequence
MIKDPRPLNDKAFIQQCIRQLCEFLTENGYAHNVSMKSLQAPSVKDFLKIFTFLYGFLCPSYELPDTKFEEEVPRIFKDLGYPFALSKSSMYTVGAPHTWPHIVAALVWLIDCIKIHTAMKESSGEETEDGIMHNKLFLDYTIKCYESFMSGADSFDEMNAELQSKLKDLFNVDAFKLESLEAKNRALNEQIARLEQERSTANKANAERLKRLQKSADLYKDRLGLEIRFTNINPESPFRKAFTAT
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Implications for Kinetochore-Microtubule Attachment from the Structure of an Engineered Ndc80 Complex
pubmed doi rcsb
molecule keywords KINETOCHORE PROTEIN HEC1, KINETOCHORE PROTEIN SPC25
molecule tags Cell cycle
source organism Homo sapiens
total genus 62
structure length 246
sequence length 312
chains with identical sequence B
ec nomenclature
pdb deposition date 2007-10-17

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF18077 DUF5595 Domain of unknown function (DUF5595)
A PF08234 Spindle_Spc25 Chromosome segregation protein Spc25
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.418.30 Mainly Alpha Orthogonal Bundle Actin-binding Protein, T-fimbrin; domain 1 Actin-binding Protein, T-fimbrin; domain 1 2ve7A01
2VE7A 2IGPA
chains in the Genus database with same CATH superfamily
1MB8A 2D85A 2RR8A 5A4BA 1P2XA 2HKPA 2YRNA 3JALM 4B7LA 3JAKM 2VZCA 1WYRA 2JV9A 1SH5A 1P5SA 2WA7A 1DXXA 4EDMA 5A37A 4LVPA 1H67A 1WYQA 5A38A 1WIXA 2DK9A 3HOPA 1BHDA 3I6XA 2WA6A 2HL9A 2R0OA 1WYPA 1PA7A 1WKUA 2D88A 3CO1A 5J8EA 1UJOA 1TJTA 1RT8A 1WJOA 3HOCA 1QAGA 4Q57B 2R8UA 2VZDA 1SH6A 1WYLA 4EDLA 1AOAA 2L3GA 2QJZA 2VE7A 2HL8A 1VKAA 2EQOA 2EYIA 5L0OA 2D89A 4LVRA 1EUVA 2D86A 2K3SA 5FMUA 3VP7A 1WYNA 4DDPA 1BKRA 2K2RA 3KY9A 2VZGB 2EYNA 4Q59A 1UEGA 5A36A 4EDNA 3KMUB 2WE6A 1WYMA 1AA2A 2VZIB 2WFNA 4Q58A 5FMTA 3REPB 3HORA 2EE7A 2QJXA 2E9KA 2VE7C 5BVRA 3EAYA 2IGPA 3F7PA 2WDTA 1WYOA 3JARM 4TXIA 1PXYA 1V5KA 3FERA 4TXKA 2WA5A 2D87A 3KMWB
chains in the Genus database with same CATH topology
2WDTA 2VE7A 4DDPA 2VE7C 4LVPA 4LVRA 5FMTA 1EUVA 2HL8A 2IGPA 2WE6A 3EAYA 2EQOA 2HKPA 5FMUA 3VP7A 2HL9A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2VE7 A;  2IGP A; 
#chains in the Genus database with same CATH topology
 1MB8 A;  2D85 A;  2RR8 A;  5A4B A;  1P2X A;  2HKP A;  2YRN A;  3JAL M;  4B7L A;  3JAK M;  2VZC A;  1WYR A;  2JV9 A;  1SH5 A;  1P5S A;  2WA7 A;  1DXX A;  4EDM A;  5A37 A;  4LVP A;  1H67 A;  1WYQ A;  5A38 A;  1WIX A;  2DK9 A;  3HOP A;  1BHD A;  3I6X A;  2WA6 A;  2HL9 A;  2R0O A;  1WYP A;  1PA7 A;  1WKU A;  2D88 A;  3CO1 A;  5J8E A;  1UJO A;  1TJT A;  1RT8 A;  1WJO A;  3HOC A;  1QAG A;  4Q57 B;  2R8U A;  2VZD A;  1SH6 A;  1WYL A;  4EDL A;  1AOA A;  2L3G A;  2QJZ A;  2VE7 A;  2HL8 A;  1VKA A;  2EQO A;  2EYI A;  5L0O A;  2D89 A;  4LVR A;  1EUV A;  2D86 A;  2K3S A;  5FMU A;  3VP7 A;  1WYN A;  4DDP A;  1BKR A;  2K2R A;  3KY9 A;  2VZG B;  2EYN A;  4Q59 A;  1UEG A;  5A36 A;  4EDN A;  3KMU B;  2WE6 A;  1WYM A;  1AA2 A;  2VZI B;  2WFN A;  4Q58 A;  5FMT A;  3REP B;  3HOR A;  2EE7 A;  2QJX A;  2E9K A;  2VE7 C;  5BVR A;  3EAY A;  2IGP A;  3F7P A;  2WDT A;  1WYO A;  3JAR M;  4TXI A;  1PXY A;  1V5K A;  3FER A;  4TXK A;  2WA5 A;  2D87 A;  3KMW B; 
#chains in the Genus database with same CATH homology
 2WDT A;  2VE7 A;  4DDP A;  2VE7 C;  4LVP A;  4LVR A;  5FMT A;  1EUV A;  2HL8 A;  2IGP A;  2WE6 A;  3EAY A;  2EQO A;  2HKP A;  5FMU A;  3VP7 A;  2HL9 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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