2VE7A

Crystal structure of a bonsai version of the human ndc80 complex
Total Genus 62
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
62
sequence length
312
structure length
246
Chain Sequence
MIKDPRPLNDKAFIQQCIRQLCEFLTENGYAHNVSMKSLQAPSVKDFLKIFTFLYGFLCPSYELPDTKFEEEVPRIFKDLGYPFALSKSSMYTVGAPHTWPHIVAALVWLIDCIKIHTAMKESSGEETEDGIMHNKLFLDYTIKCYESFMSGADSFDEMNAELQSKLKDLFNVDAFKLESLEAKNRALNEQIARLEQERSTANKANAERLKRLQKSADLYKDRLGLEIRFTNINPESPFRKAFTAT
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Implications for Kinetochore-Microtubule Attachment from the Structure of an Engineered Ndc80 Complex
pubmed doi rcsb
molecule keywords KINETOCHORE PROTEIN HEC1, KINETOCHORE PROTEIN SPC25
molecule tags Cell cycle
source organism Homo sapiens
total genus 62
structure length 246
sequence length 312
chains with identical sequence B
ec nomenclature
pdb deposition date 2007-10-17

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF18077 DUF5595 Domain of unknown function (DUF5595)
A PF08234 Spindle_Spc25 Chromosome segregation protein Spc25
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.418.30 Mainly Alpha Orthogonal Bundle Actin-binding Protein, T-fimbrin; domain 1 Actin-binding Protein, T-fimbrin; domain 1 2ve7A01
2IGPA 2VE7A
chains in the Genus database with same CATH superfamily
3KY9A 2VZIB 1UJOA 2WA6A 2WA5A 4Q58A 1MB8A 2D85A 2RR8A 2D88A 5J8EA 2QJXA 2WE6A 3HOCA 2EYNA 1WIXA 1WJOA 1WYOA 2R8UA 5L0OA 1SH6A 2EE7A 5A38A 1WYPA 5A37A 2IGPA 3VP7A 3FERA 4EDLA 2VZGB 1UEGA 2L3GA 2JV9A 2K2RA 2VZCA 1SH5A 2D86A 2HL8A 4Q59A 5A36A 2EQOA 3JARM 1WKUA 5BVRA 4TXKA 4LVRA 3I6XA 5A4BA 1EUVA 2WDTA 3KMUB 3HOPA 1WYNA 2WA7A 1P5SA 4EDNA 1AA2A 1WYRA 4Q57B 3REPB 3CO1A 3JALM 2WFNA 1BHDA 2VE7C 3HORA 2VE7A 3JAKM 2EYIA 2VZDA 1P2XA 1PA7A 2E9KA 1V5KA 1WYQA 1RT8A 3EAYA 2K3SA 2YRNA 2DK9A 1PXYA 1QAGA 4LVPA 1BKRA 1AOAA 3KMWB 2HL9A 2QJZA 2HKPA 4EDMA 1TJTA 3F7PA 1H67A 1WYLA 1WYMA 5FMUA 1DXXA 2R0OA 4DDPA 4TXIA 2D87A 2D89A 4B7LA 5FMTA 1VKAA
chains in the Genus database with same CATH topology
2HL8A 2VE7C 3VP7A 1EUVA 3EAYA 2VE7A 2WDTA 2EQOA 4LVPA 2WE6A 4DDPA 2IGPA 5FMTA 2HL9A 2HKPA 4LVRA 5FMUA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2IGP A;  2VE7 A; 
#chains in the Genus database with same CATH topology
 3KY9 A;  2VZI B;  1UJO A;  2WA6 A;  2WA5 A;  4Q58 A;  1MB8 A;  2D85 A;  2RR8 A;  2D88 A;  5J8E A;  2QJX A;  2WE6 A;  3HOC A;  2EYN A;  1WIX A;  1WJO A;  1WYO A;  2R8U A;  5L0O A;  1SH6 A;  2EE7 A;  5A38 A;  1WYP A;  5A37 A;  2IGP A;  3VP7 A;  3FER A;  4EDL A;  2VZG B;  1UEG A;  2L3G A;  2JV9 A;  2K2R A;  2VZC A;  1SH5 A;  2D86 A;  2HL8 A;  4Q59 A;  5A36 A;  2EQO A;  3JAR M;  1WKU A;  5BVR A;  4TXK A;  4LVR A;  3I6X A;  5A4B A;  1EUV A;  2WDT A;  3KMU B;  3HOP A;  1WYN A;  2WA7 A;  1P5S A;  4EDN A;  1AA2 A;  1WYR A;  4Q57 B;  3REP B;  3CO1 A;  3JAL M;  2WFN A;  1BHD A;  2VE7 C;  3HOR A;  2VE7 A;  3JAK M;  2EYI A;  2VZD A;  1P2X A;  1PA7 A;  2E9K A;  1V5K A;  1WYQ A;  1RT8 A;  3EAY A;  2K3S A;  2YRN A;  2DK9 A;  1PXY A;  1QAG A;  4LVP A;  1BKR A;  1AOA A;  3KMW B;  2HL9 A;  2QJZ A;  2HKP A;  4EDM A;  1TJT A;  3F7P A;  1H67 A;  1WYL A;  1WYM A;  5FMU A;  1DXX A;  2R0O A;  4DDP A;  4TXI A;  2D87 A;  2D89 A;  4B7L A;  5FMT A;  1VKA A; 
#chains in the Genus database with same CATH homology
 2HL8 A;  2VE7 C;  3VP7 A;  1EUV A;  3EAY A;  2VE7 A;  2WDT A;  2EQO A;  4LVP A;  2WE6 A;  4DDP A;  2IGP A;  5FMT A;  2HL9 A;  2HKP A;  4LVR A;  5FMU A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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