2VE7A

Crystal structure of a bonsai version of the human ndc80 complex
Total Genus 62
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
62
sequence length
312
structure length
246
Chain Sequence
MIKDPRPLNDKAFIQQCIRQLCEFLTENGYAHNVSMKSLQAPSVKDFLKIFTFLYGFLCPSYELPDTKFEEEVPRIFKDLGYPFALSKSSMYTVGAPHTWPHIVAALVWLIDCIKIHTAMKESSGEETEDGIMHNKLFLDYTIKCYESFMSGADSFDEMNAELQSKLKDLFNVDAFKLESLEAKNRALNEQIARLEQERSTANKANAERLKRLQKSADLYKDRLGLEIRFTNINPESPFRKAFTAT
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Implications for Kinetochore-Microtubule Attachment from the Structure of an Engineered Ndc80 Complex
pubmed doi rcsb
molecule keywords KINETOCHORE PROTEIN HEC1, KINETOCHORE PROTEIN SPC25
molecule tags Cell cycle
source organism Homo sapiens
total genus 62
structure length 246
sequence length 312
chains with identical sequence B
ec nomenclature
pdb deposition date 2007-10-17

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF18077 DUF5595 Domain of unknown function (DUF5595)
A PF08234 Spindle_Spc25 Chromosome segregation protein Spc25
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.418.30 Mainly Alpha Orthogonal Bundle Actin-binding Protein, T-fimbrin; domain 1 Actin-binding Protein, T-fimbrin; domain 1 2ve7A01
2VE7A 2IGPA
chains in the Genus database with same CATH superfamily
3JARM 1BKRA 3EAYA 1WYNA 4EDMA 2QJZA 2VZGB 3REPB 3I6XA 5FMUA 5A38A 5J8EA 1DXXA 2WFNA 1RT8A 4EDNA 2WA7A 4EDLA 5BVRA 2D89A 3HORA 1H67A 4LVRA 2VE7C 1AOAA 1EUVA 1TJTA 3VP7A 5FMTA 1UEGA 2DK9A 1VKAA 2IGPA 2D86A 4TXIA 4Q58A 2HL8A 2VZIB 1WYOA 2HKPA 2VE7A 4DDPA 1AA2A 2VZCA 3F7PA 3HOCA 3CO1A 1BHDA 1WYPA 1SH6A 1QAGA 2E9KA 2QJXA 3KMWB 3HOPA 1WYRA 2WE6A 2WA5A 2D85A 2JV9A 1P5SA 1MB8A 1WYMA 1UJOA 1P2XA 2HL9A 2L3GA 2WA6A 3JAKM 2EYIA 2R8UA 2YRNA 3JALM 3KMUB 4Q57B 1WJOA 4B7LA 5A36A 2D87A 2D88A 5A37A 1SH5A 1PXYA 1WYLA 5L0OA 5A4BA 2K2RA 4LVPA 1WYQA 2EE7A 1V5KA 2R0OA 1WKUA 2RR8A 1PA7A 2VZDA 3FERA 2EQOA 3KY9A 4TXKA 2WDTA 2EYNA 2K3SA 1WIXA 4Q59A
chains in the Genus database with same CATH topology
2HL8A 2IGPA 2HKPA 2WE6A 3VP7A 3EAYA 4DDPA 4LVRA 2WDTA 5FMTA 2VE7C 2EQOA 5FMUA 2VE7A 4LVPA 2HL9A 1EUVA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2VE7 A;  2IGP A; 
#chains in the Genus database with same CATH topology
 3JAR M;  1BKR A;  3EAY A;  1WYN A;  4EDM A;  2QJZ A;  2VZG B;  3REP B;  3I6X A;  5FMU A;  5A38 A;  5J8E A;  1DXX A;  2WFN A;  1RT8 A;  4EDN A;  2WA7 A;  4EDL A;  5BVR A;  2D89 A;  3HOR A;  1H67 A;  4LVR A;  2VE7 C;  1AOA A;  1EUV A;  1TJT A;  3VP7 A;  5FMT A;  1UEG A;  2DK9 A;  1VKA A;  2IGP A;  2D86 A;  4TXI A;  4Q58 A;  2HL8 A;  2VZI B;  1WYO A;  2HKP A;  2VE7 A;  4DDP A;  1AA2 A;  2VZC A;  3F7P A;  3HOC A;  3CO1 A;  1BHD A;  1WYP A;  1SH6 A;  1QAG A;  2E9K A;  2QJX A;  3KMW B;  3HOP A;  1WYR A;  2WE6 A;  2WA5 A;  2D85 A;  2JV9 A;  1P5S A;  1MB8 A;  1WYM A;  1UJO A;  1P2X A;  2HL9 A;  2L3G A;  2WA6 A;  3JAK M;  2EYI A;  2R8U A;  2YRN A;  3JAL M;  3KMU B;  4Q57 B;  1WJO A;  4B7L A;  5A36 A;  2D87 A;  2D88 A;  5A37 A;  1SH5 A;  1PXY A;  1WYL A;  5L0O A;  5A4B A;  2K2R A;  4LVP A;  1WYQ A;  2EE7 A;  1V5K A;  2R0O A;  1WKU A;  2RR8 A;  1PA7 A;  2VZD A;  3FER A;  2EQO A;  3KY9 A;  4TXK A;  2WDT A;  2EYN A;  2K3S A;  1WIX A;  4Q59 A; 
#chains in the Genus database with same CATH homology
 2HL8 A;  2IGP A;  2HKP A;  2WE6 A;  3VP7 A;  3EAY A;  4DDP A;  4LVR A;  2WDT A;  5FMT A;  2VE7 C;  2EQO A;  5FMU A;  2VE7 A;  4LVP A;  2HL9 A;  1EUV A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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