2VE7A

Crystal structure of a bonsai version of the human ndc80 complex
Total Genus 62
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
62
sequence length
312
structure length
246
Chain Sequence
MIKDPRPLNDKAFIQQCIRQLCEFLTENGYAHNVSMKSLQAPSVKDFLKIFTFLYGFLCPSYELPDTKFEEEVPRIFKDLGYPFALSKSSMYTVGAPHTWPHIVAALVWLIDCIKIHTAMKESSGEETEDGIMHNKLFLDYTIKCYESFMSGADSFDEMNAELQSKLKDLFNVDAFKLESLEAKNRALNEQIARLEQERSTANKANAERLKRLQKSADLYKDRLGLEIRFTNINPESPFRKAFTAT
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Cell cycle
source organism Homo sapiens
publication title Implications for Kinetochore-Microtubule Attachment from the Structure of an Engineered Ndc80 Complex
pubmed doi rcsb
molecule keywords KINETOCHORE PROTEIN HEC1, KINETOCHORE PROTEIN SPC25
total genus 62
structure length 246
sequence length 312
chains with identical sequence B
ec nomenclature
pdb deposition date 2007-10-17

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF18077 DUF5595 Domain of unknown function (DUF5595)
A PF08234 Spindle_Spc25 Chromosome segregation protein Spc25
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.418.30 Mainly Alpha Orthogonal Bundle Actin-binding Protein, T-fimbrin; domain 1 Actin-binding Protein, T-fimbrin; domain 1 2ve7A01
2VE7A 2IGPA
chains in the Genus database with same CATH superfamily
2JV9A 3CO1A 1WYNA 2D86A 1UEGA 2IGPA 1H67A 3FERA 1WJOA 1WYMA 2HKPA 1SH5A 4LVRA 1P2XA 1MB8A 4EDMA 2K3SA 5FMTA 2HL8A 2WA6A 3KMUB 4B7LA 1DXXA 5A36A 3HORA 3JALM 2E9KA 4EDLA 2WA7A 1WYQA 3JARM 4DDPA 2VZIB 3JAKM 4LVPA 2EQOA 2VZGB 1PA7A 3VP7A 5A4BA 2WDTA 1BKRA 1AA2A 2D89A 1WYPA 2WA5A 2VE7C 2K2RA 2QJZA 2L3GA 4TXIA 5A37A 4Q58A 1TJTA 5L0OA 1PXYA 2YRNA 4EDNA 2HL9A 2D85A 1QAGA 2R8UA 5A38A 2VZDA 1WYOA 2QJXA 2WE6A 2D88A 3KY9A 1UJOA 2EYIA 1WIXA 3KMWB 3EAYA 2EYNA 2DK9A 5BVRA 2VE7A 3HOPA 1EUVA 2RR8A 5FMUA 2WFNA 1WYRA 1VKAA 3I6XA 4Q59A 2D87A 1BHDA 1V5KA 1SH6A 1AOAA 2EE7A 1WKUA 1P5SA 3F7PA 1RT8A 1WYLA 3HOCA 4Q57B 3REPB 2R0OA 2VZCA 5J8EA 4TXKA
chains in the Genus database with same CATH topology
1EUVA 2HKPA 2WDTA 2WE6A 2IGPA 5FMTA 4LVRA 4LVPA 2HL8A 5FMUA 2EQOA 2HL9A 3EAYA 4DDPA 2VE7A 3VP7A 2VE7C
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2VE7 A;  2IGP A; 
#chains in the Genus database with same CATH topology
 2JV9 A;  3CO1 A;  1WYN A;  2D86 A;  1UEG A;  2IGP A;  1H67 A;  3FER A;  1WJO A;  1WYM A;  2HKP A;  1SH5 A;  4LVR A;  1P2X A;  1MB8 A;  4EDM A;  2K3S A;  5FMT A;  2HL8 A;  2WA6 A;  3KMU B;  4B7L A;  1DXX A;  5A36 A;  3HOR A;  3JAL M;  2E9K A;  4EDL A;  2WA7 A;  1WYQ A;  3JAR M;  4DDP A;  2VZI B;  3JAK M;  4LVP A;  2EQO A;  2VZG B;  1PA7 A;  3VP7 A;  5A4B A;  2WDT A;  1BKR A;  1AA2 A;  2D89 A;  1WYP A;  2WA5 A;  2VE7 C;  2K2R A;  2QJZ A;  2L3G A;  4TXI A;  5A37 A;  4Q58 A;  1TJT A;  5L0O A;  1PXY A;  2YRN A;  4EDN A;  2HL9 A;  2D85 A;  1QAG A;  2R8U A;  5A38 A;  2VZD A;  1WYO A;  2QJX A;  2WE6 A;  2D88 A;  3KY9 A;  1UJO A;  2EYI A;  1WIX A;  3KMW B;  3EAY A;  2EYN A;  2DK9 A;  5BVR A;  2VE7 A;  3HOP A;  1EUV A;  2RR8 A;  5FMU A;  2WFN A;  1WYR A;  1VKA A;  3I6X A;  4Q59 A;  2D87 A;  1BHD A;  1V5K A;  1SH6 A;  1AOA A;  2EE7 A;  1WKU A;  1P5S A;  3F7P A;  1RT8 A;  1WYL A;  3HOC A;  4Q57 B;  3REP B;  2R0O A;  2VZC A;  5J8E A;  4TXK A; 
#chains in the Genus database with same CATH homology
 1EUV A;  2HKP A;  2WDT A;  2WE6 A;  2IGP A;  5FMT A;  4LVR A;  4LVP A;  2HL8 A;  5FMU A;  2EQO A;  2HL9 A;  3EAY A;  4DDP A;  2VE7 A;  3VP7 A;  2VE7 C; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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