2VZC | Genus

Total Genus 49

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus	49
sequence length	127
structure length	127
Chain Sequence	ERDAFDTLFDHAPDKLNVVKKTLITFVNKHLNKLNLEVTELETQFADGVYLVLLMGLLEGYFVPLHSFFLTPDSFEQKVLNVSFAFELMQDGGLEKPKPRPEDIVNCDLKSTLRVLYNLFTKYRNVE

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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

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After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Genus data interpretation

molecule tags	Cell adhesion
source organism	Homo sapiens
publication title	Structural Analysis of the Interactions between Paxillin Ld Motifs and Alpha-Parvin pubmed doi rcsb
molecule keywords	ALPHA-PARVIN
total genus	49
structure length	127
sequence length	127
chains with identical sequence	B
ec nomenclature
pdb deposition date	2008-07-31

pfam database annotations

chain	Pfam Accession Code	Pfam Family Identifier	Pfam Description
A	PF00307	CH	Calponin homology (CH) domain

Image from the rcsb pdb (www.rcsb.org)

cath code	Class	Architecture	Topology	Homology	Domain
1.10.418.10	Mainly Alpha	Orthogonal Bundle	Actin-binding Protein, T-fimbrin; domain 1	Calponin-like domain	2vzcA00

1WKUA 5A37A 2D89A 1BHDA 2WA6A 3HOCA 2K3SA 2VZDA 3JARM 2D86A 1SH6A 2K2RA 5A36A 5L0OA 3KY9A 4TXKA 2JV9A 3HORA 2R0OA 1WYPA 2WA5A 3KMWB 2EYNA 2RR8A 5J8EA 1P5SA 3KMUB 3FERA 1WIXA 4EDLA 3F7PA 1DXXA 1AA2A 5A4BA 1WYRA 2E9KA 2VZGB 2QJXA 4TXIA 1VKAA 3HOPA 2WFNA 1V5KA 2QJZA 5BVRA 1BKRA 2R8UA 2EE7A 2VZCA 2YRNA 1WYQA 3CO1A 1H67A 4Q57B 1WYNA 3JALM 1WYLA 4B7LA 1WYOA 2VZIB 1P2XA 5A38A 3REPB 2D87A 1TJTA 1MB8A 4EDMA 1UEGA 1PA7A 1QAGA 2D85A 1RT8A 3I6XA 3JAKM 4EDNA 4Q58A 2DK9A 2EYIA 1WJOA 1WYMA 1UJOA 1PXYA 2L3GA 4Q59A 1AOAA 1SH5A 2D88A 2WA7A
chains in the Genus database with same CATH superfamily

1WKUA 2WE6A 5A37A 2D89A 1BHDA 1EUVA 2HL8A 2WA6A 3HOCA 2K3SA 2VZDA 3JARM 2D86A 1SH6A 2K2RA 3EAYA 5A36A 5L0OA 3KY9A 4TXKA 2JV9A 3HORA 2R0OA 1WYPA 4DDPA 2WA5A 3KMWB 2EYNA 2RR8A 5J8EA 1P5SA 3KMUB 3FERA 1WIXA 4EDLA 3F7PA 1DXXA 2WDTA 1AA2A 5A4BA 1WYRA 2E9KA 2VZGB 2QJXA 4TXIA 5FMTA 1VKAA 3HOPA 2WFNA 2HL9A 2VE7C 2HKPA 2EQOA 1V5KA 2QJZA 5BVRA 1BKRA 2R8UA 2EE7A 2VZCA 2YRNA 5FMUA 1WYQA 3CO1A 1H67A 4Q57B 1WYNA 3JALM 1WYLA 4B7LA 1WYOA 4LVPA 2VZIB 1P2XA 5A38A 3REPB 2D87A 2VE7A 1TJTA 1MB8A 4EDMA 1UEGA 1PA7A 1QAGA 2D85A 1RT8A 3VP7A 3I6XA 3JAKM 4EDNA 4Q58A 2DK9A 2EYIA 1WJOA 1WYMA 2IGPA 1UJOA 1PXYA 4LVRA 2L3GA 4Q59A 1AOAA 1SH5A 2D88A 2WA7A
chains in the Genus database with same CATH topology

#chains in the Genus database with same CATH superfamily
 1WKU A;  5A37 A;  2D89 A;  1BHD A;  2WA6 A;  3HOC A;  2K3S A;  2VZD A;  3JAR M;  2D86 A;  1SH6 A;  2K2R A;  5A36 A;  5L0O A;  3KY9 A;  4TXK A;  2JV9 A;  3HOR A;  2R0O A;  1WYP A;  2WA5 A;  3KMW B;  2EYN A;  2RR8 A;  5J8E A;  1P5S A;  3KMU B;  3FER A;  1WIX A;  4EDL A;  3F7P A;  1DXX A;  1AA2 A;  5A4B A;  1WYR A;  2E9K A;  2VZG B;  2QJX A;  4TXI A;  1VKA A;  3HOP A;  2WFN A;  1V5K A;  2QJZ A;  5BVR A;  1BKR A;  2R8U A;  2EE7 A;  2VZC A;  2YRN A;  1WYQ A;  3CO1 A;  1H67 A;  4Q57 B;  1WYN A;  3JAL M;  1WYL A;  4B7L A;  1WYO A;  2VZI B;  1P2X A;  5A38 A;  3REP B;  2D87 A;  1TJT A;  1MB8 A;  4EDM A;  1UEG A;  1PA7 A;  1QAG A;  2D85 A;  1RT8 A;  3I6X A;  3JAK M;  4EDN A;  4Q58 A;  2DK9 A;  2EYI A;  1WJO A;  1WYM A;  1UJO A;  1PXY A;  2L3G A;  4Q59 A;  1AOA A;  1SH5 A;  2D88 A;  2WA7 A; 
#chains in the Genus database with same CATH topology
 1WKU A;  2WE6 A;  5A37 A;  2D89 A;  1BHD A;  1EUV A;  2HL8 A;  2WA6 A;  3HOC A;  2K3S A;  2VZD A;  3JAR M;  2D86 A;  1SH6 A;  2K2R A;  3EAY A;  5A36 A;  5L0O A;  3KY9 A;  4TXK A;  2JV9 A;  3HOR A;  2R0O A;  1WYP A;  4DDP A;  2WA5 A;  3KMW B;  2EYN A;  2RR8 A;  5J8E A;  1P5S A;  3KMU B;  3FER A;  1WIX A;  4EDL A;  3F7P A;  1DXX A;  2WDT A;  1AA2 A;  5A4B A;  1WYR A;  2E9K A;  2VZG B;  2QJX A;  4TXI A;  5FMT A;  1VKA A;  3HOP A;  2WFN A;  2HL9 A;  2VE7 C;  2HKP A;  2EQO A;  1V5K A;  2QJZ A;  5BVR A;  1BKR A;  2R8U A;  2EE7 A;  2VZC A;  2YRN A;  5FMU A;  1WYQ A;  3CO1 A;  1H67 A;  4Q57 B;  1WYN A;  3JAL M;  1WYL A;  4B7L A;  1WYO A;  4LVP A;  2VZI B;  1P2X A;  5A38 A;  3REP B;  2D87 A;  2VE7 A;  1TJT A;  1MB8 A;  4EDM A;  1UEG A;  1PA7 A;  1QAG A;  2D85 A;  1RT8 A;  3VP7 A;  3I6X A;  3JAK M;  4EDN A;  4Q58 A;  2DK9 A;  2EYI A;  1WJO A;  1WYM A;  2IGP A;  1UJO A;  1PXY A;  4LVR A;  2L3G A;  4Q59 A;  1AOA A;  1SH5 A;  2D88 A;  2WA7 A; 
#chains in the Genus database with same CATH homology
 1WKU A;  5A37 A;  2D89 A;  1BHD A;  2WA6 A;  3HOC A;  2K3S A;  2VZD A;  3JAR M;  2D86 A;  1SH6 A;  2K2R A;  5A36 A;  5L0O A;  3KY9 A;  4TXK A;  2JV9 A;  3HOR A;  2R0O A;  1WYP A;  2WA5 A;  3KMW B;  2EYN A;  2RR8 A;  5J8E A;  1P5S A;  3KMU B;  3FER A;  1WIX A;  4EDL A;  3F7P A;  1DXX A;  1AA2 A;  5A4B A;  1WYR A;  2E9K A;  2VZG B;  2QJX A;  4TXI A;  1VKA A;  3HOP A;  2WFN A;  1V5K A;  2QJZ A;  5BVR A;  1BKR A;  2R8U A;  2EE7 A;  2VZC A;  2YRN A;  1WYQ A;  3CO1 A;  1H67 A;  4Q57 B;  1WYN A;  3JAL M;  1WYL A;  4B7L A;  1WYO A;  2VZI B;  1P2X A;  5A38 A;  3REP B;  2D87 A;  1TJT A;  1MB8 A;  4EDM A;  1UEG A;  1PA7 A;  1QAG A;  2D85 A;  1RT8 A;  3I6X A;  3JAK M;  4EDN A;  4Q58 A;  2DK9 A;  2EYI A;  1WJO A;  1WYM A;  1UJO A;  1PXY A;  2L3G A;  4Q59 A;  1AOA A;  1SH5 A;  2D88 A;  2WA7 A;

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similar chains in the Genus database (?% sequence similarity)

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similar chains in the pdb database (?% sequence similarity)

#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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2VZCA

Total Genus

sequence length

structure length

Chain Sequence

Structure visualization

pfam database annotations