2VZDA

Crystal structure of the c-terminal calponin homology domain of alpha parvin in complex with paxillin ld1 motif
Total Genus 47
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
47
sequence length
127
structure length
127
Chain Sequence
ERDAFDTLFDHAPDKLNVVKKTLITFVNKHLNKLNLEVTELETQFADGVYLVLLMGLLEGYFVPLHSFFLTPDSFEQKVLNVSFAFELMQDGGLEKPKPRPEDIVNCDLKSTLRVLYNLFTKYRNVE
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Structural Analysis of the Interactions between Paxillin Ld Motifs and Alpha-Parvin
pubmed doi rcsb
molecule tags Cell adhesion
source organism Homo sapiens
molecule keywords ALPHA-PARVIN
total genus 47
structure length 127
sequence length 127
chains with identical sequence B
ec nomenclature
pdb deposition date 2008-07-31

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00307 CH Calponin homology (CH) domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.418.10 Mainly Alpha Orthogonal Bundle Actin-binding Protein, T-fimbrin; domain 1 Calponin-like domain 2vzdA00
4TXKA 2WA5A 2JV9A 1WYRA 1UEGA 1SH6A 3KMUB 1BHDA 4Q57B 2QJZA 5L0OA 1TJTA 2EYIA 3HOPA 5A4BA 1AOAA 1WYMA 2EYNA 1WKUA 2EE7A 1UJOA 1V5KA 3I6XA 2E9KA 2R8UA 2WA7A 3REPB 3KMWB 4EDMA 4TXIA 4EDLA 1WYLA 1MB8A 2QJXA 3HORA 1BKRA 3JAKM 5A38A 2WFNA 2VZIB 1RT8A 1WYPA 2WA6A 2DK9A 1WIXA 1VKAA 1DXXA 3F7PA 3JARM 4EDNA 3JALM 1WJOA 5BVRA 2D87A 2VZDA 2D85A 2L3GA 2VZCA 2K3SA 2D86A 2D88A 4Q59A 2YRNA 1WYOA 2K2RA 3CO1A 2R0OA 1PXYA 1WYNA 1AA2A 1P2XA 5A37A 1P5SA 1SH5A 4B7LA 1PA7A 5A36A 2D89A 1WYQA 2VZGB 2RR8A 3KY9A 1H67A 3FERA 5J8EA 4Q58A 1QAGA 3HOCA
chains in the Genus database with same CATH superfamily
2WE6A 4TXKA 2VE7A 2WA5A 2JV9A 1WYRA 1UEGA 4LVPA 1SH6A 3KMUB 1BHDA 4Q57B 2QJZA 5L0OA 1TJTA 2EYIA 3HOPA 5A4BA 2WDTA 1AOAA 1WYMA 2EYNA 1WKUA 2EE7A 2HL9A 1UJOA 1V5KA 2VE7C 3I6XA 2E9KA 2R8UA 2WA7A 3REPB 3KMWB 4EDMA 4TXIA 4EDLA 2IGPA 1WYLA 1MB8A 2QJXA 3HORA 1BKRA 3JAKM 5A38A 2WFNA 2VZIB 1RT8A 1WYPA 5FMTA 2WA6A 1EUVA 2DK9A 1WIXA 1VKAA 1DXXA 3F7PA 3JARM 4EDNA 3JALM 1WJOA 5BVRA 3VP7A 2D87A 2VZDA 2D85A 2L3GA 2VZCA 2K3SA 2D86A 2D88A 4Q59A 2YRNA 1WYOA 2K2RA 3CO1A 2HL8A 2R0OA 1PXYA 1WYNA 1AA2A 1P2XA 5FMUA 3EAYA 5A37A 1P5SA 2EQOA 1SH5A 4B7LA 4LVRA 1PA7A 5A36A 2HKPA 2D89A 1WYQA 2VZGB 2RR8A 3KY9A 1H67A 4DDPA 3FERA 5J8EA 4Q58A 1QAGA 3HOCA
chains in the Genus database with same CATH topology
4TXKA 2WA5A 2JV9A 1WYRA 1UEGA 1SH6A 3KMUB 1BHDA 4Q57B 2QJZA 5L0OA 1TJTA 2EYIA 3HOPA 5A4BA 1AOAA 1WYMA 2EYNA 1WKUA 2EE7A 1UJOA 1V5KA 3I6XA 2E9KA 2R8UA 2WA7A 3REPB 3KMWB 4EDMA 4TXIA 4EDLA 1WYLA 1MB8A 2QJXA 3HORA 1BKRA 3JAKM 5A38A 2WFNA 2VZIB 1RT8A 1WYPA 2WA6A 2DK9A 1WIXA 1VKAA 1DXXA 3F7PA 3JARM 4EDNA 3JALM 1WJOA 5BVRA 2D87A 2VZDA 2D85A 2L3GA 2VZCA 2K3SA 2D86A 2D88A 4Q59A 2YRNA 1WYOA 2K2RA 3CO1A 2R0OA 1PXYA 1WYNA 1AA2A 1P2XA 5A37A 1P5SA 1SH5A 4B7LA 1PA7A 5A36A 2D89A 1WYQA 2VZGB 2RR8A 3KY9A 1H67A 3FERA 5J8EA 4Q58A 1QAGA 3HOCA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4TXK A;  2WA5 A;  2JV9 A;  1WYR A;  1UEG A;  1SH6 A;  3KMU B;  1BHD A;  4Q57 B;  2QJZ A;  5L0O A;  1TJT A;  2EYI A;  3HOP A;  5A4B A;  1AOA A;  1WYM A;  2EYN A;  1WKU A;  2EE7 A;  1UJO A;  1V5K A;  3I6X A;  2E9K A;  2R8U A;  2WA7 A;  3REP B;  3KMW B;  4EDM A;  4TXI A;  4EDL A;  1WYL A;  1MB8 A;  2QJX A;  3HOR A;  1BKR A;  3JAK M;  5A38 A;  2WFN A;  2VZI B;  1RT8 A;  1WYP A;  2WA6 A;  2DK9 A;  1WIX A;  1VKA A;  1DXX A;  3F7P A;  3JAR M;  4EDN A;  3JAL M;  1WJO A;  5BVR A;  2D87 A;  2VZD A;  2D85 A;  2L3G A;  2VZC A;  2K3S A;  2D86 A;  2D88 A;  4Q59 A;  2YRN A;  1WYO A;  2K2R A;  3CO1 A;  2R0O A;  1PXY A;  1WYN A;  1AA2 A;  1P2X A;  5A37 A;  1P5S A;  1SH5 A;  4B7L A;  1PA7 A;  5A36 A;  2D89 A;  1WYQ A;  2VZG B;  2RR8 A;  3KY9 A;  1H67 A;  3FER A;  5J8E A;  4Q58 A;  1QAG A;  3HOC A; 
#chains in the Genus database with same CATH topology
 2WE6 A;  4TXK A;  2VE7 A;  2WA5 A;  2JV9 A;  1WYR A;  1UEG A;  4LVP A;  1SH6 A;  3KMU B;  1BHD A;  4Q57 B;  2QJZ A;  5L0O A;  1TJT A;  2EYI A;  3HOP A;  5A4B A;  2WDT A;  1AOA A;  1WYM A;  2EYN A;  1WKU A;  2EE7 A;  2HL9 A;  1UJO A;  1V5K A;  2VE7 C;  3I6X A;  2E9K A;  2R8U A;  2WA7 A;  3REP B;  3KMW B;  4EDM A;  4TXI A;  4EDL A;  2IGP A;  1WYL A;  1MB8 A;  2QJX A;  3HOR A;  1BKR A;  3JAK M;  5A38 A;  2WFN A;  2VZI B;  1RT8 A;  1WYP A;  5FMT A;  2WA6 A;  1EUV A;  2DK9 A;  1WIX A;  1VKA A;  1DXX A;  3F7P A;  3JAR M;  4EDN A;  3JAL M;  1WJO A;  5BVR A;  3VP7 A;  2D87 A;  2VZD A;  2D85 A;  2L3G A;  2VZC A;  2K3S A;  2D86 A;  2D88 A;  4Q59 A;  2YRN A;  1WYO A;  2K2R A;  3CO1 A;  2HL8 A;  2R0O A;  1PXY A;  1WYN A;  1AA2 A;  1P2X A;  5FMU A;  3EAY A;  5A37 A;  1P5S A;  2EQO A;  1SH5 A;  4B7L A;  4LVR A;  1PA7 A;  5A36 A;  2HKP A;  2D89 A;  1WYQ A;  2VZG B;  2RR8 A;  3KY9 A;  1H67 A;  4DDP A;  3FER A;  5J8E A;  4Q58 A;  1QAG A;  3HOC A; 
#chains in the Genus database with same CATH homology
 4TXK A;  2WA5 A;  2JV9 A;  1WYR A;  1UEG A;  1SH6 A;  3KMU B;  1BHD A;  4Q57 B;  2QJZ A;  5L0O A;  1TJT A;  2EYI A;  3HOP A;  5A4B A;  1AOA A;  1WYM A;  2EYN A;  1WKU A;  2EE7 A;  1UJO A;  1V5K A;  3I6X A;  2E9K A;  2R8U A;  2WA7 A;  3REP B;  3KMW B;  4EDM A;  4TXI A;  4EDL A;  1WYL A;  1MB8 A;  2QJX A;  3HOR A;  1BKR A;  3JAK M;  5A38 A;  2WFN A;  2VZI B;  1RT8 A;  1WYP A;  2WA6 A;  2DK9 A;  1WIX A;  1VKA A;  1DXX A;  3F7P A;  3JAR M;  4EDN A;  3JAL M;  1WJO A;  5BVR A;  2D87 A;  2VZD A;  2D85 A;  2L3G A;  2VZC A;  2K3S A;  2D86 A;  2D88 A;  4Q59 A;  2YRN A;  1WYO A;  2K2R A;  3CO1 A;  2R0O A;  1PXY A;  1WYN A;  1AA2 A;  1P2X A;  5A37 A;  1P5S A;  1SH5 A;  4B7L A;  1PA7 A;  5A36 A;  2D89 A;  1WYQ A;  2VZG B;  2RR8 A;  3KY9 A;  1H67 A;  3FER A;  5J8E A;  4Q58 A;  1QAG A;  3HOC A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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#similar chains, but unknotted
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