2WFNA

Filamin a actin binding domain
Total Genus 67
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
67
sequence length
238
structure length
227
Chain Sequence
WKKIQQNTFTRWCNEHLKCVSKRIANLQTDLSDGLRLIALLEVLSQKKMHRKHNQRPTFRQMQLENVSVALEFLDRESIKLVSIDSKAIVDGNLKLILGLIWTLILHYSISMPMQTPKQRLLGWIQNKLPQLPITNFSRDWQSGRALGALVDSCAPGLCPDWDSWDASKPVTNAREAMQQADDWLGIPQVITPEEIVDPNVDEHSVMTYLSQFPKAKLKPGAPLRPK
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
{{ tooltip.sname }} connected with {{ tooltip.tname }} : {{qFormat(tooltip.svalue) }}
molecule tags Contractile protein
source organism Homo sapiens
publication title Structure of the Human Filamin a Actin-Binding Domain
pubmed doi rcsb
molecule keywords FILAMIN-A
total genus 67
structure length 227
sequence length 238
chains with identical sequence B
ec nomenclature
pdb deposition date 2009-04-09

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00307 CH Calponin homology (CH) domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.418.10 Mainly Alpha Orthogonal Bundle Actin-binding Protein, T-fimbrin; domain 1 Calponin-like domain 2wfnA01
1.10.418.10 Mainly Alpha Orthogonal Bundle Actin-binding Protein, T-fimbrin; domain 1 Calponin-like domain 2wfnA02
2D89A 2VZGB 2QJXA 5A37A 1QAGA 1WYOA 3F7PA 2VZCA 2EYNA 2D87A 5L0OA 1PA7A 1VKAA 3KMUB 1P5SA 1WYRA 1AOAA 1WIXA 4EDMA 3HORA 1SH6A 1WYLA 4Q59A 1WJOA 5BVRA 3JALM 3CO1A 2R8UA 1UEGA 2D85A 3JAKM 1WYQA 1WYNA 2D86A 4TXKA 1BKRA 2RR8A 2JV9A 1RT8A 4TXIA 3I6XA 5J8EA 1H67A 3KMWB 1DXXA 2WFNA 2WA5A 1P2XA 5A38A 3KY9A 2VZDA 2DK9A 2WA7A 3HOPA 1PXYA 1UJOA 2EE7A 2L3GA 1AA2A 2VZIB 1SH5A 2R0OA 1WYMA 2QJZA 3REPB 4B7LA 1BHDA 1WKUA 2K2RA 2YRNA 2WA6A 2E9KA 1MB8A 1V5KA 4EDLA 2K3SA 4Q58A 5A36A 1TJTA 2D88A 3FERA 4Q57B 3JARM 2EYIA 3HOCA 4EDNA 1WYPA 5A4BA
chains in the Genus database with same CATH superfamily
2D89A 3VP7A 2VZGB 2QJXA 5A37A 1QAGA 1WYOA 3F7PA 2VZCA 4DDPA 2EYNA 2D87A 5L0OA 1PA7A 1VKAA 2WE6A 3KMUB 3EAYA 1P5SA 1WYRA 1AOAA 2HL9A 1WIXA 4EDMA 3HORA 2IGPA 1SH6A 1WYLA 4Q59A 2VE7C 1WJOA 5BVRA 3JALM 3CO1A 2R8UA 1UEGA 2D85A 3JAKM 1WYQA 1WYNA 2D86A 1EUVA 4TXKA 1BKRA 2RR8A 2JV9A 1RT8A 4TXIA 3I6XA 5J8EA 1H67A 2EQOA 3KMWB 1DXXA 2WFNA 2WA5A 1P2XA 5A38A 3KY9A 2VZDA 2DK9A 2HKPA 2WA7A 3HOPA 1PXYA 1UJOA 2EE7A 2L3GA 1AA2A 2VZIB 1SH5A 2R0OA 1WYMA 2HL8A 4LVRA 2WDTA 2QJZA 3REPB 2VE7A 4B7LA 1BHDA 4LVPA 1WKUA 5FMUA 2K2RA 2YRNA 2WA6A 2E9KA 1MB8A 1V5KA 5FMTA 4EDLA 2K3SA 4Q58A 5A36A 1TJTA 2D88A 3FERA 4Q57B 3JARM 2EYIA 3HOCA 4EDNA 1WYPA 5A4BA
chains in the Genus database with same CATH topology
2D89A 2VZGB 2QJXA 5A37A 1QAGA 1WYOA 3F7PA 2VZCA 2EYNA 2D87A 5L0OA 1PA7A 1VKAA 3KMUB 1P5SA 1WYRA 1AOAA 1WIXA 4EDMA 3HORA 1SH6A 1WYLA 4Q59A 1WJOA 5BVRA 3JALM 3CO1A 2R8UA 1UEGA 2D85A 3JAKM 1WYQA 1WYNA 2D86A 4TXKA 1BKRA 2RR8A 2JV9A 1RT8A 4TXIA 3I6XA 5J8EA 1H67A 3KMWB 1DXXA 2WFNA 2WA5A 1P2XA 5A38A 3KY9A 2VZDA 2DK9A 2WA7A 3HOPA 1PXYA 1UJOA 2EE7A 2L3GA 1AA2A 2VZIB 1SH5A 2R0OA 1WYMA 2QJZA 3REPB 4B7LA 1BHDA 1WKUA 2K2RA 2YRNA 2WA6A 2E9KA 1MB8A 1V5KA 4EDLA 2K3SA 4Q58A 5A36A 1TJTA 2D88A 3FERA 4Q57B 3JARM 2EYIA 3HOCA 4EDNA 1WYPA 5A4BA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2D89 A;  2VZG B;  2QJX A;  5A37 A;  1QAG A;  1WYO A;  3F7P A;  2VZC A;  2EYN A;  2D87 A;  5L0O A;  1PA7 A;  1VKA A;  3KMU B;  1P5S A;  1WYR A;  1AOA A;  1WIX A;  4EDM A;  3HOR A;  1SH6 A;  1WYL A;  4Q59 A;  1WJO A;  5BVR A;  3JAL M;  3CO1 A;  2R8U A;  1UEG A;  2D85 A;  3JAK M;  1WYQ A;  1WYN A;  2D86 A;  4TXK A;  1BKR A;  2RR8 A;  2JV9 A;  1RT8 A;  4TXI A;  3I6X A;  5J8E A;  1H67 A;  3KMW B;  1DXX A;  2WFN A;  2WA5 A;  1P2X A;  5A38 A;  3KY9 A;  2VZD A;  2DK9 A;  2WA7 A;  3HOP A;  1PXY A;  1UJO A;  2EE7 A;  2L3G A;  1AA2 A;  2VZI B;  1SH5 A;  2R0O A;  1WYM A;  2QJZ A;  3REP B;  4B7L A;  1BHD A;  1WKU A;  2K2R A;  2YRN A;  2WA6 A;  2E9K A;  1MB8 A;  1V5K A;  4EDL A;  2K3S A;  4Q58 A;  5A36 A;  1TJT A;  2D88 A;  3FER A;  4Q57 B;  3JAR M;  2EYI A;  3HOC A;  4EDN A;  1WYP A;  5A4B A; 
#chains in the Genus database with same CATH topology
 2D89 A;  3VP7 A;  2VZG B;  2QJX A;  5A37 A;  1QAG A;  1WYO A;  3F7P A;  2VZC A;  4DDP A;  2EYN A;  2D87 A;  5L0O A;  1PA7 A;  1VKA A;  2WE6 A;  3KMU B;  3EAY A;  1P5S A;  1WYR A;  1AOA A;  2HL9 A;  1WIX A;  4EDM A;  3HOR A;  2IGP A;  1SH6 A;  1WYL A;  4Q59 A;  2VE7 C;  1WJO A;  5BVR A;  3JAL M;  3CO1 A;  2R8U A;  1UEG A;  2D85 A;  3JAK M;  1WYQ A;  1WYN A;  2D86 A;  1EUV A;  4TXK A;  1BKR A;  2RR8 A;  2JV9 A;  1RT8 A;  4TXI A;  3I6X A;  5J8E A;  1H67 A;  2EQO A;  3KMW B;  1DXX A;  2WFN A;  2WA5 A;  1P2X A;  5A38 A;  3KY9 A;  2VZD A;  2DK9 A;  2HKP A;  2WA7 A;  3HOP A;  1PXY A;  1UJO A;  2EE7 A;  2L3G A;  1AA2 A;  2VZI B;  1SH5 A;  2R0O A;  1WYM A;  2HL8 A;  4LVR A;  2WDT A;  2QJZ A;  3REP B;  2VE7 A;  4B7L A;  1BHD A;  4LVP A;  1WKU A;  5FMU A;  2K2R A;  2YRN A;  2WA6 A;  2E9K A;  1MB8 A;  1V5K A;  5FMT A;  4EDL A;  2K3S A;  4Q58 A;  5A36 A;  1TJT A;  2D88 A;  3FER A;  4Q57 B;  3JAR M;  2EYI A;  3HOC A;  4EDN A;  1WYP A;  5A4B A; 
#chains in the Genus database with same CATH homology
 2D89 A;  2VZG B;  2QJX A;  5A37 A;  1QAG A;  1WYO A;  3F7P A;  2VZC A;  2EYN A;  2D87 A;  5L0O A;  1PA7 A;  1VKA A;  3KMU B;  1P5S A;  1WYR A;  1AOA A;  1WIX A;  4EDM A;  3HOR A;  1SH6 A;  1WYL A;  4Q59 A;  1WJO A;  5BVR A;  3JAL M;  3CO1 A;  2R8U A;  1UEG A;  2D85 A;  3JAK M;  1WYQ A;  1WYN A;  2D86 A;  4TXK A;  1BKR A;  2RR8 A;  2JV9 A;  1RT8 A;  4TXI A;  3I6X A;  5J8E A;  1H67 A;  3KMW B;  1DXX A;  2WFN A;  2WA5 A;  1P2X A;  5A38 A;  3KY9 A;  2VZD A;  2DK9 A;  2WA7 A;  3HOP A;  1PXY A;  1UJO A;  2EE7 A;  2L3G A;  1AA2 A;  2VZI B;  1SH5 A;  2R0O A;  1WYM A;  2QJZ A;  3REP B;  4B7L A;  1BHD A;  1WKU A;  2K2R A;  2YRN A;  2WA6 A;  2E9K A;  1MB8 A;  1V5K A;  4EDL A;  2K3S A;  4Q58 A;  5A36 A;  1TJT A;  2D88 A;  3FER A;  4Q57 B;  3JAR M;  2EYI A;  3HOC A;  4EDN A;  1WYP A;  5A4B A; 
...loading similar chains, please wait...
similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
#similar chains, but unknotted
...loading similar chains, please wait...
#similar chains in the pdb database (?% sequence similarity)
...loading similar chains, please wait...