2WN4A

Structural basis for substrate recognition in the enzymatic component of adp-ribosyltransferase toxin cdta from clostridium difficile
Total Genus 134
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
134
sequence length
393
structure length
391
Chain Sequence
RKEAERIEQKLERSEKEALESYKKDSVEISKYSQTRNYFYDYQIEANSREKEYKELRNAISKNKIDKPMYVYYFESPEKFAFNKVIRTENQNEISLEKFNEFKETIQNKLFKQDGFKDISLYEPGKGDEKPTPLLMHLKLPRNTGMLPYTNTVSTLIEQGYSIKIDKIVRIVIDGKHYIKAEASVVSSLDFKDDVSKGDSWGKANYNDWSNKLTPNELADVNDYMRGGYTAINNYLISNGPVNNPNPELDSKITNIENALKREPIPTNLTVYRRSGPQEFGLTLTSPEYDFNKLENIDAFKSKWEGQALSYPNFISTSIGSVNMSAFAKRKIVLRITIPKGSPGAYLSAIPGYAGEYEVLLNHGSKFKINKIDSYKDGTITKLIVDATLIP
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural Basis for Substrate Recognition in the Enzymatic Component of Adp-Ribosyltransferase Toxin Cdta from Clostridium Difficile.
pubmed doi rcsb
molecule tags Transferase
source organism Clostridium difficile
molecule keywords ADP-RIBOSYLTRANSFERASE ENZYMATIC COMPONENT
total genus 134
structure length 391
sequence length 393
ec nomenclature
pdb deposition date 2009-07-07

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF03496 ADPrib_exo_Tox ADP-ribosyltransferase exoenzyme
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.176.10 Alpha Beta Alpha-Beta Complex Toxin ADP-ribosyltransferase; Chain A, domain 1 Toxin ADP-ribosyltransferase; Chain A, domain 1 2wn4A02
3.90.176.10 Alpha Beta Alpha-Beta Complex Toxin ADP-ribosyltransferase; Chain A, domain 1 Toxin ADP-ribosyltransferase; Chain A, domain 1 2wn4A01
4TR5A 2BOVB 4H0YA 2C8FE 4H0VA 1JKYA 4XM6A 1OJQA 4XSHB 1PWPA 2C8GA 3BW8A 4GF1A 5BWMB 2C8AA 1QS1A 1ZXVA 1G24A 2WN4A 2C8DA 2J3ZA 4H0TA 1J7NA 1GY0A 5D1TA 2C8HA 1QS2A 4XM8A 4PKVA 1PWQA 4H0XA 4PKQA 2A78B 4GY2A 2C8BX 1GXYA 4PKRA 1GXZA 1R4BA 2WN5A 4PKSA 2C89A 1PWVA 4FK7A 4PKTA 1OG1A 2C8CA 2C8EE 2J3XA 2GWLA 2WN7A 5DZQA 1PWUA 1GZEA 5H04A 2WN6A 2J3VA 4FMLA 5D1SA 1GIQA 4XM7A 1UZIA 3BUZA 1OJZA 2WN8A 5GTTA 5H03A 4H03A 1YQYA 5D1UA 3U0JA 2GWMA 4ELNA 3NTSA 4DV8A 4FXQA 4WF6A 1R45A 1PWWA 1GZFA 4PKUA 2A9KB 1GIRA 4PKWA 4XSGB 1OG4A 1OG3A
chains in the Genus database with same CATH superfamily
4TR5A 2BOVB 4H0YA 2C8FE 4H0VA 1JKYA 4XM6A 1OJQA 4XSHB 1PWPA 2C8GA 3BW8A 4GF1A 5BWMB 2C8AA 1QS1A 1ZXVA 1G24A 2WN4A 2C8DA 2J3ZA 4H0TA 1J7NA 1GY0A 5D1TA 2C8HA 1QS2A 4XM8A 4PKVA 1PWQA 4H0XA 4PKQA 2A78B 4GY2A 2C8BX 1GXYA 4PKRA 1GXZA 1R4BA 2WN5A 4PKSA 2C89A 1PWVA 4FK7A 4PKTA 1OG1A 2C8CA 2C8EE 2J3XA 2GWLA 2WN7A 5DZQA 1PWUA 1GZEA 5H04A 2WN6A 2J3VA 4FMLA 5D1SA 1GIQA 4XM7A 1UZIA 3BUZA 1OJZA 2WN8A 5GTTA 5H03A 4H03A 1YQYA 5D1UA 3U0JA 2GWMA 4ELNA 3NTSA 4DV8A 4FXQA 4WF6A 1R45A 1PWWA 1GZFA 4PKUA 2A9KB 1GIRA 4PKWA 4XSGB 1OG4A 1OG3A
chains in the Genus database with same CATH topology
4TR5A 2BOVB 4H0YA 2C8FE 4H0VA 1JKYA 4XM6A 1OJQA 4XSHB 1PWPA 2C8GA 3BW8A 4GF1A 5BWMB 2C8AA 1QS1A 1ZXVA 1G24A 2WN4A 2C8DA 2J3ZA 4H0TA 1J7NA 1GY0A 5D1TA 2C8HA 1QS2A 4XM8A 4PKVA 1PWQA 4H0XA 4PKQA 2A78B 4GY2A 2C8BX 1GXYA 4PKRA 1GXZA 1R4BA 2WN5A 4PKSA 2C89A 1PWVA 4FK7A 4PKTA 1OG1A 2C8CA 2C8EE 2J3XA 2GWLA 2WN7A 5DZQA 1PWUA 1GZEA 5H04A 2WN6A 2J3VA 4FMLA 5D1SA 1GIQA 4XM7A 1UZIA 3BUZA 1OJZA 2WN8A 5GTTA 5H03A 4H03A 1YQYA 5D1UA 3U0JA 2GWMA 4ELNA 3NTSA 4DV8A 4FXQA 4WF6A 1R45A 1PWWA 1GZFA 4PKUA 2A9KB 1GIRA 4PKWA 4XSGB 1OG4A 1OG3A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4TR5 A;  2BOV B;  4H0Y A;  2C8F E;  4H0V A;  1JKY A;  4XM6 A;  1OJQ A;  4XSH B;  1PWP A;  2C8G A;  3BW8 A;  4GF1 A;  5BWM B;  2C8A A;  1QS1 A;  1ZXV A;  1G24 A;  2WN4 A;  2C8D A;  2J3Z A;  4H0T A;  1J7N A;  1GY0 A;  5D1T A;  2C8H A;  1QS2 A;  4XM8 A;  4PKV A;  1PWQ A;  4H0X A;  4PKQ A;  2A78 B;  4GY2 A;  2C8B X;  1GXY A;  4PKR A;  1GXZ A;  1R4B A;  2WN5 A;  4PKS A;  2C89 A;  1PWV A;  4FK7 A;  4PKT A;  1OG1 A;  2C8C A;  2C8E E;  2J3X A;  2GWL A;  2WN7 A;  5DZQ A;  1PWU A;  1GZE A;  5H04 A;  2WN6 A;  2J3V A;  4FML A;  5D1S A;  1GIQ A;  4XM7 A;  1UZI A;  3BUZ A;  1OJZ A;  2WN8 A;  5GTT A;  5H03 A;  4H03 A;  1YQY A;  5D1U A;  3U0J A;  2GWM A;  4ELN A;  3NTS A;  4DV8 A;  4FXQ A;  4WF6 A;  1R45 A;  1PWW A;  1GZF A;  4PKU A;  2A9K B;  1GIR A;  4PKW A;  4XSG B;  1OG4 A;  1OG3 A; 
#chains in the Genus database with same CATH topology
 4TR5 A;  2BOV B;  4H0Y A;  2C8F E;  4H0V A;  1JKY A;  4XM6 A;  1OJQ A;  4XSH B;  1PWP A;  2C8G A;  3BW8 A;  4GF1 A;  5BWM B;  2C8A A;  1QS1 A;  1ZXV A;  1G24 A;  2WN4 A;  2C8D A;  2J3Z A;  4H0T A;  1J7N A;  1GY0 A;  5D1T A;  2C8H A;  1QS2 A;  4XM8 A;  4PKV A;  1PWQ A;  4H0X A;  4PKQ A;  2A78 B;  4GY2 A;  2C8B X;  1GXY A;  4PKR A;  1GXZ A;  1R4B A;  2WN5 A;  4PKS A;  2C89 A;  1PWV A;  4FK7 A;  4PKT A;  1OG1 A;  2C8C A;  2C8E E;  2J3X A;  2GWL A;  2WN7 A;  5DZQ A;  1PWU A;  1GZE A;  5H04 A;  2WN6 A;  2J3V A;  4FML A;  5D1S A;  1GIQ A;  4XM7 A;  1UZI A;  3BUZ A;  1OJZ A;  2WN8 A;  5GTT A;  5H03 A;  4H03 A;  1YQY A;  5D1U A;  3U0J A;  2GWM A;  4ELN A;  3NTS A;  4DV8 A;  4FXQ A;  4WF6 A;  1R45 A;  1PWW A;  1GZF A;  4PKU A;  2A9K B;  1GIR A;  4PKW A;  4XSG B;  1OG4 A;  1OG3 A; 
#chains in the Genus database with same CATH homology
 4TR5 A;  2BOV B;  4H0Y A;  2C8F E;  4H0V A;  1JKY A;  4XM6 A;  1OJQ A;  4XSH B;  1PWP A;  2C8G A;  3BW8 A;  4GF1 A;  5BWM B;  2C8A A;  1QS1 A;  1ZXV A;  1G24 A;  2WN4 A;  2C8D A;  2J3Z A;  4H0T A;  1J7N A;  1GY0 A;  5D1T A;  2C8H A;  1QS2 A;  4XM8 A;  4PKV A;  1PWQ A;  4H0X A;  4PKQ A;  2A78 B;  4GY2 A;  2C8B X;  1GXY A;  4PKR A;  1GXZ A;  1R4B A;  2WN5 A;  4PKS A;  2C89 A;  1PWV A;  4FK7 A;  4PKT A;  1OG1 A;  2C8C A;  2C8E E;  2J3X A;  2GWL A;  2WN7 A;  5DZQ A;  1PWU A;  1GZE A;  5H04 A;  2WN6 A;  2J3V A;  4FML A;  5D1S A;  1GIQ A;  4XM7 A;  1UZI A;  3BUZ A;  1OJZ A;  2WN8 A;  5GTT A;  5H03 A;  4H03 A;  1YQY A;  5D1U A;  3U0J A;  2GWM A;  4ELN A;  3NTS A;  4DV8 A;  4FXQ A;  4WF6 A;  1R45 A;  1PWW A;  1GZF A;  4PKU A;  2A9K B;  1GIR A;  4PKW A;  4XSG B;  1OG4 A;  1OG3 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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