2WN5A

Structural basis for substrate recognition in the enzymatic component of adp-ribosyltransferase toxin cdta from clostridium difficile
Total Genus 132
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
132
sequence length
397
structure length
394
Chain Sequence
KEWERKEAERIEQKLERSEKEALESYKKDSVEISKYSQTRNYFYDYQIEANSREKEYKELRNAISKNKIDKPMYVYYFESPEKFAFNKVIRTENQNEISLEKFNEFKETIQNKLFKQDGFKDISLYEPGKGDEKPTPLLMHLKLPRNTGMLPYTNNNVSTLIEQGYSIKIDKIVRIVIDGKHYIKAEASVVSSLDFKDDVSKGDSWGKANYNDWSNKLTPNELADVNDYMRGGYTAINNYLISNGPVNNPNPELDSKITNIENALKREPIPTNLTVYRRSGPQEFGLTLTSPEYDFNKLENIDAFKSKWEGQALSYPNFISTSIGSVNMSAFAKRKIVLRITIPKGSPGAYLSAIPGYEYEVLLNHGSKFKINKIDSYKDGTITKLIVDATLIP
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Transferase
source organism Clostridium difficile
publication title Structural Basis for Substrate Recognition in the Enzymatic Component of Adp-Ribosyltransferase Toxin Cdta from Clostridium Difficile.
pubmed doi rcsb
molecule keywords ADP-RIBOSYLTRANSFERASE ENZYMATIC COMPONENT
total genus 132
structure length 394
sequence length 397
ec nomenclature
pdb deposition date 2009-07-07

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF03496 ADPrib_exo_Tox ADP-ribosyltransferase exoenzyme
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.176.10 Alpha Beta Alpha-Beta Complex Toxin ADP-ribosyltransferase; Chain A, domain 1 Toxin ADP-ribosyltransferase; Chain A, domain 1 2wn5A02
3.90.176.10 Alpha Beta Alpha-Beta Complex Toxin ADP-ribosyltransferase; Chain A, domain 1 Toxin ADP-ribosyltransferase; Chain A, domain 1 2wn5A01
1JKYA 1UZIA 2A9KB 1GZEA 5H03A 3BW8A 4XSGB 4PKVA 1PWWA 5DZQA 4XM7A 4PKUA 2J3XA 4H0YA 4GF1A 1R45A 2J3VA 4PKTA 4H0VA 2GWMA 1GIQA 4GY2A 3BUZA 4PKRA 2BOVB 5D1UA 4FMLA 1OG4A 5H04A 1OJZA 1OG3A 4ELNA 5D1TA 4WF6A 3NTSA 4PKSA 2C89A 2WN5A 4H0TA 1OG1A 2C8CA 1GXYA 1GXZA 2A78B 2GWLA 4PKQA 5D1SA 1QS2A 4FXQA 2C8BX 3U0JA 2WN7A 2C8EE 2C8HA 1GIRA 4XM6A 4H03A 1PWUA 1PWPA 1ZXVA 1J7NA 2C8FE 4H0XA 1G24A 2J3ZA 1GZFA 4XSHB 5BWMB 4PKWA 4DV8A 1R4BA 1YQYA 2WN6A 5GTTA 1QS1A 4FK7A 2WN4A 4XM8A 2C8DA 1PWQA 2WN8A 1PWVA 4TR5A 1OJQA 2C8GA 2C8AA 1GY0A
chains in the Genus database with same CATH superfamily
1JKYA 1UZIA 2A9KB 1GZEA 5H03A 3BW8A 4XSGB 4PKVA 1PWWA 5DZQA 4XM7A 4PKUA 2J3XA 4H0YA 4GF1A 1R45A 2J3VA 4PKTA 4H0VA 2GWMA 1GIQA 4GY2A 3BUZA 4PKRA 2BOVB 5D1UA 4FMLA 1OG4A 5H04A 1OJZA 1OG3A 4ELNA 5D1TA 4WF6A 3NTSA 4PKSA 2C89A 2WN5A 4H0TA 1OG1A 2C8CA 1GXYA 1GXZA 2A78B 2GWLA 4PKQA 5D1SA 1QS2A 4FXQA 2C8BX 3U0JA 2WN7A 2C8EE 2C8HA 1GIRA 4XM6A 4H03A 1PWUA 1PWPA 1ZXVA 1J7NA 2C8FE 4H0XA 1G24A 2J3ZA 1GZFA 4XSHB 5BWMB 4PKWA 4DV8A 1R4BA 1YQYA 2WN6A 5GTTA 1QS1A 4FK7A 2WN4A 4XM8A 2C8DA 1PWQA 2WN8A 1PWVA 4TR5A 1OJQA 2C8GA 2C8AA 1GY0A
chains in the Genus database with same CATH topology
1JKYA 1UZIA 2A9KB 1GZEA 5H03A 3BW8A 4XSGB 4PKVA 1PWWA 5DZQA 4XM7A 4PKUA 2J3XA 4H0YA 4GF1A 1R45A 2J3VA 4PKTA 4H0VA 2GWMA 1GIQA 4GY2A 3BUZA 4PKRA 2BOVB 5D1UA 4FMLA 1OG4A 5H04A 1OJZA 1OG3A 4ELNA 5D1TA 4WF6A 3NTSA 4PKSA 2C89A 2WN5A 4H0TA 1OG1A 2C8CA 1GXYA 1GXZA 2A78B 2GWLA 4PKQA 5D1SA 1QS2A 4FXQA 2C8BX 3U0JA 2WN7A 2C8EE 2C8HA 1GIRA 4XM6A 4H03A 1PWUA 1PWPA 1ZXVA 1J7NA 2C8FE 4H0XA 1G24A 2J3ZA 1GZFA 4XSHB 5BWMB 4PKWA 4DV8A 1R4BA 1YQYA 2WN6A 5GTTA 1QS1A 4FK7A 2WN4A 4XM8A 2C8DA 1PWQA 2WN8A 1PWVA 4TR5A 1OJQA 2C8GA 2C8AA 1GY0A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1JKY A;  1UZI A;  2A9K B;  1GZE A;  5H03 A;  3BW8 A;  4XSG B;  4PKV A;  1PWW A;  5DZQ A;  4XM7 A;  4PKU A;  2J3X A;  4H0Y A;  4GF1 A;  1R45 A;  2J3V A;  4PKT A;  4H0V A;  2GWM A;  1GIQ A;  4GY2 A;  3BUZ A;  4PKR A;  2BOV B;  5D1U A;  4FML A;  1OG4 A;  5H04 A;  1OJZ A;  1OG3 A;  4ELN A;  5D1T A;  4WF6 A;  3NTS A;  4PKS A;  2C89 A;  2WN5 A;  4H0T A;  1OG1 A;  2C8C A;  1GXY A;  1GXZ A;  2A78 B;  2GWL A;  4PKQ A;  5D1S A;  1QS2 A;  4FXQ A;  2C8B X;  3U0J A;  2WN7 A;  2C8E E;  2C8H A;  1GIR A;  4XM6 A;  4H03 A;  1PWU A;  1PWP A;  1ZXV A;  1J7N A;  2C8F E;  4H0X A;  1G24 A;  2J3Z A;  1GZF A;  4XSH B;  5BWM B;  4PKW A;  4DV8 A;  1R4B A;  1YQY A;  2WN6 A;  5GTT A;  1QS1 A;  4FK7 A;  2WN4 A;  4XM8 A;  2C8D A;  1PWQ A;  2WN8 A;  1PWV A;  4TR5 A;  1OJQ A;  2C8G A;  2C8A A;  1GY0 A; 
#chains in the Genus database with same CATH topology
 1JKY A;  1UZI A;  2A9K B;  1GZE A;  5H03 A;  3BW8 A;  4XSG B;  4PKV A;  1PWW A;  5DZQ A;  4XM7 A;  4PKU A;  2J3X A;  4H0Y A;  4GF1 A;  1R45 A;  2J3V A;  4PKT A;  4H0V A;  2GWM A;  1GIQ A;  4GY2 A;  3BUZ A;  4PKR A;  2BOV B;  5D1U A;  4FML A;  1OG4 A;  5H04 A;  1OJZ A;  1OG3 A;  4ELN A;  5D1T A;  4WF6 A;  3NTS A;  4PKS A;  2C89 A;  2WN5 A;  4H0T A;  1OG1 A;  2C8C A;  1GXY A;  1GXZ A;  2A78 B;  2GWL A;  4PKQ A;  5D1S A;  1QS2 A;  4FXQ A;  2C8B X;  3U0J A;  2WN7 A;  2C8E E;  2C8H A;  1GIR A;  4XM6 A;  4H03 A;  1PWU A;  1PWP A;  1ZXV A;  1J7N A;  2C8F E;  4H0X A;  1G24 A;  2J3Z A;  1GZF A;  4XSH B;  5BWM B;  4PKW A;  4DV8 A;  1R4B A;  1YQY A;  2WN6 A;  5GTT A;  1QS1 A;  4FK7 A;  2WN4 A;  4XM8 A;  2C8D A;  1PWQ A;  2WN8 A;  1PWV A;  4TR5 A;  1OJQ A;  2C8G A;  2C8A A;  1GY0 A; 
#chains in the Genus database with same CATH homology
 1JKY A;  1UZI A;  2A9K B;  1GZE A;  5H03 A;  3BW8 A;  4XSG B;  4PKV A;  1PWW A;  5DZQ A;  4XM7 A;  4PKU A;  2J3X A;  4H0Y A;  4GF1 A;  1R45 A;  2J3V A;  4PKT A;  4H0V A;  2GWM A;  1GIQ A;  4GY2 A;  3BUZ A;  4PKR A;  2BOV B;  5D1U A;  4FML A;  1OG4 A;  5H04 A;  1OJZ A;  1OG3 A;  4ELN A;  5D1T A;  4WF6 A;  3NTS A;  4PKS A;  2C89 A;  2WN5 A;  4H0T A;  1OG1 A;  2C8C A;  1GXY A;  1GXZ A;  2A78 B;  2GWL A;  4PKQ A;  5D1S A;  1QS2 A;  4FXQ A;  2C8B X;  3U0J A;  2WN7 A;  2C8E E;  2C8H A;  1GIR A;  4XM6 A;  4H03 A;  1PWU A;  1PWP A;  1ZXV A;  1J7N A;  2C8F E;  4H0X A;  1G24 A;  2J3Z A;  1GZF A;  4XSH B;  5BWM B;  4PKW A;  4DV8 A;  1R4B A;  1YQY A;  2WN6 A;  5GTT A;  1QS1 A;  4FK7 A;  2WN4 A;  4XM8 A;  2C8D A;  1PWQ A;  2WN8 A;  1PWV A;  4TR5 A;  1OJQ A;  2C8G A;  2C8A A;  1GY0 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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