2WN5A

Structural basis for substrate recognition in the enzymatic component of adp-ribosyltransferase toxin cdta from clostridium difficile
Total Genus 132
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
132
sequence length
397
structure length
394
Chain Sequence
KEWERKEAERIEQKLERSEKEALESYKKDSVEISKYSQTRNYFYDYQIEANSREKEYKELRNAISKNKIDKPMYVYYFESPEKFAFNKVIRTENQNEISLEKFNEFKETIQNKLFKQDGFKDISLYEPGKGDEKPTPLLMHLKLPRNTGMLPYTNNNVSTLIEQGYSIKIDKIVRIVIDGKHYIKAEASVVSSLDFKDDVSKGDSWGKANYNDWSNKLTPNELADVNDYMRGGYTAINNYLISNGPVNNPNPELDSKITNIENALKREPIPTNLTVYRRSGPQEFGLTLTSPEYDFNKLENIDAFKSKWEGQALSYPNFISTSIGSVNMSAFAKRKIVLRITIPKGSPGAYLSAIPGYEYEVLLNHGSKFKINKIDSYKDGTITKLIVDATLIP
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural Basis for Substrate Recognition in the Enzymatic Component of Adp-Ribosyltransferase Toxin Cdta from Clostridium Difficile.
pubmed doi rcsb
molecule tags Transferase
source organism Clostridium difficile
molecule keywords ADP-RIBOSYLTRANSFERASE ENZYMATIC COMPONENT
total genus 132
structure length 394
sequence length 397
ec nomenclature
pdb deposition date 2009-07-07

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF03496 ADPrib_exo_Tox ADP-ribosyltransferase exoenzyme
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.176.10 Alpha Beta Alpha-Beta Complex Toxin ADP-ribosyltransferase; Chain A, domain 1 Toxin ADP-ribosyltransferase; Chain A, domain 1 2wn5A02
3.90.176.10 Alpha Beta Alpha-Beta Complex Toxin ADP-ribosyltransferase; Chain A, domain 1 Toxin ADP-ribosyltransferase; Chain A, domain 1 2wn5A01
2C8HA 5BWMB 2WN6A 4FXQA 1OJZA 2C8AA 4GY2A 4H03A 1GZFA 4DV8A 1OG3A 2C8FE 1PWWA 2BOVB 4PKQA 1ZXVA 2WN7A 4H0VA 5H03A 5D1SA 4XM7A 1G24A 1QS1A 2C8DA 3BUZA 3NTSA 2A78B 1YQYA 1OG4A 4H0XA 4PKTA 4PKUA 4GF1A 1OG1A 1PWPA 2GWMA 2WN8A 5GTTA 2J3VA 5D1UA 1R45A 1PWUA 4PKSA 5H04A 1OJQA 5DZQA 2A9KB 2C8BX 4XSGB 2GWLA 1PWQA 1QS2A 4XM8A 1J7NA 2C89A 1GIRA 4XSHB 2WN5A 2J3ZA 4WF6A 3U0JA 2C8GA 1PWVA 2J3XA 1GZEA 4H0TA 1GY0A 4H0YA 1GXYA 4XM6A 4ELNA 4PKRA 1GIQA 1R4BA 3BW8A 4TR5A 5D1TA 4PKVA 4PKWA 1JKYA 2C8CA 4FMLA 4FK7A 1UZIA 2WN4A 2C8EE 1GXZA
chains in the Genus database with same CATH superfamily
2C8HA 5BWMB 2WN6A 4FXQA 1OJZA 2C8AA 4GY2A 4H03A 1GZFA 4DV8A 1OG3A 2C8FE 1PWWA 2BOVB 4PKQA 1ZXVA 2WN7A 4H0VA 5H03A 5D1SA 4XM7A 1G24A 1QS1A 2C8DA 3BUZA 3NTSA 2A78B 1YQYA 1OG4A 4H0XA 4PKTA 4PKUA 4GF1A 1OG1A 1PWPA 2GWMA 2WN8A 5GTTA 2J3VA 5D1UA 1R45A 1PWUA 4PKSA 5H04A 1OJQA 5DZQA 2A9KB 2C8BX 4XSGB 2GWLA 1PWQA 1QS2A 4XM8A 1J7NA 2C89A 1GIRA 4XSHB 2WN5A 2J3ZA 4WF6A 3U0JA 2C8GA 1PWVA 2J3XA 1GZEA 4H0TA 1GY0A 4H0YA 1GXYA 4XM6A 4ELNA 4PKRA 1GIQA 1R4BA 3BW8A 4TR5A 5D1TA 4PKVA 4PKWA 1JKYA 2C8CA 4FMLA 4FK7A 1UZIA 2WN4A 2C8EE 1GXZA
chains in the Genus database with same CATH topology
2C8HA 5BWMB 2WN6A 4FXQA 1OJZA 2C8AA 4GY2A 4H03A 1GZFA 4DV8A 1OG3A 2C8FE 1PWWA 2BOVB 4PKQA 1ZXVA 2WN7A 4H0VA 5H03A 5D1SA 4XM7A 1G24A 1QS1A 2C8DA 3BUZA 3NTSA 2A78B 1YQYA 1OG4A 4H0XA 4PKTA 4PKUA 4GF1A 1OG1A 1PWPA 2GWMA 2WN8A 5GTTA 2J3VA 5D1UA 1R45A 1PWUA 4PKSA 5H04A 1OJQA 5DZQA 2A9KB 2C8BX 4XSGB 2GWLA 1PWQA 1QS2A 4XM8A 1J7NA 2C89A 1GIRA 4XSHB 2WN5A 2J3ZA 4WF6A 3U0JA 2C8GA 1PWVA 2J3XA 1GZEA 4H0TA 1GY0A 4H0YA 1GXYA 4XM6A 4ELNA 4PKRA 1GIQA 1R4BA 3BW8A 4TR5A 5D1TA 4PKVA 4PKWA 1JKYA 2C8CA 4FMLA 4FK7A 1UZIA 2WN4A 2C8EE 1GXZA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2C8H A;  5BWM B;  2WN6 A;  4FXQ A;  1OJZ A;  2C8A A;  4GY2 A;  4H03 A;  1GZF A;  4DV8 A;  1OG3 A;  2C8F E;  1PWW A;  2BOV B;  4PKQ A;  1ZXV A;  2WN7 A;  4H0V A;  5H03 A;  5D1S A;  4XM7 A;  1G24 A;  1QS1 A;  2C8D A;  3BUZ A;  3NTS A;  2A78 B;  1YQY A;  1OG4 A;  4H0X A;  4PKT A;  4PKU A;  4GF1 A;  1OG1 A;  1PWP A;  2GWM A;  2WN8 A;  5GTT A;  2J3V A;  5D1U A;  1R45 A;  1PWU A;  4PKS A;  5H04 A;  1OJQ A;  5DZQ A;  2A9K B;  2C8B X;  4XSG B;  2GWL A;  1PWQ A;  1QS2 A;  4XM8 A;  1J7N A;  2C89 A;  1GIR A;  4XSH B;  2WN5 A;  2J3Z A;  4WF6 A;  3U0J A;  2C8G A;  1PWV A;  2J3X A;  1GZE A;  4H0T A;  1GY0 A;  4H0Y A;  1GXY A;  4XM6 A;  4ELN A;  4PKR A;  1GIQ A;  1R4B A;  3BW8 A;  4TR5 A;  5D1T A;  4PKV A;  4PKW A;  1JKY A;  2C8C A;  4FML A;  4FK7 A;  1UZI A;  2WN4 A;  2C8E E;  1GXZ A; 
#chains in the Genus database with same CATH topology
 2C8H A;  5BWM B;  2WN6 A;  4FXQ A;  1OJZ A;  2C8A A;  4GY2 A;  4H03 A;  1GZF A;  4DV8 A;  1OG3 A;  2C8F E;  1PWW A;  2BOV B;  4PKQ A;  1ZXV A;  2WN7 A;  4H0V A;  5H03 A;  5D1S A;  4XM7 A;  1G24 A;  1QS1 A;  2C8D A;  3BUZ A;  3NTS A;  2A78 B;  1YQY A;  1OG4 A;  4H0X A;  4PKT A;  4PKU A;  4GF1 A;  1OG1 A;  1PWP A;  2GWM A;  2WN8 A;  5GTT A;  2J3V A;  5D1U A;  1R45 A;  1PWU A;  4PKS A;  5H04 A;  1OJQ A;  5DZQ A;  2A9K B;  2C8B X;  4XSG B;  2GWL A;  1PWQ A;  1QS2 A;  4XM8 A;  1J7N A;  2C89 A;  1GIR A;  4XSH B;  2WN5 A;  2J3Z A;  4WF6 A;  3U0J A;  2C8G A;  1PWV A;  2J3X A;  1GZE A;  4H0T A;  1GY0 A;  4H0Y A;  1GXY A;  4XM6 A;  4ELN A;  4PKR A;  1GIQ A;  1R4B A;  3BW8 A;  4TR5 A;  5D1T A;  4PKV A;  4PKW A;  1JKY A;  2C8C A;  4FML A;  4FK7 A;  1UZI A;  2WN4 A;  2C8E E;  1GXZ A; 
#chains in the Genus database with same CATH homology
 2C8H A;  5BWM B;  2WN6 A;  4FXQ A;  1OJZ A;  2C8A A;  4GY2 A;  4H03 A;  1GZF A;  4DV8 A;  1OG3 A;  2C8F E;  1PWW A;  2BOV B;  4PKQ A;  1ZXV A;  2WN7 A;  4H0V A;  5H03 A;  5D1S A;  4XM7 A;  1G24 A;  1QS1 A;  2C8D A;  3BUZ A;  3NTS A;  2A78 B;  1YQY A;  1OG4 A;  4H0X A;  4PKT A;  4PKU A;  4GF1 A;  1OG1 A;  1PWP A;  2GWM A;  2WN8 A;  5GTT A;  2J3V A;  5D1U A;  1R45 A;  1PWU A;  4PKS A;  5H04 A;  1OJQ A;  5DZQ A;  2A9K B;  2C8B X;  4XSG B;  2GWL A;  1PWQ A;  1QS2 A;  4XM8 A;  1J7N A;  2C89 A;  1GIR A;  4XSH B;  2WN5 A;  2J3Z A;  4WF6 A;  3U0J A;  2C8G A;  1PWV A;  2J3X A;  1GZE A;  4H0T A;  1GY0 A;  4H0Y A;  1GXY A;  4XM6 A;  4ELN A;  4PKR A;  1GIQ A;  1R4B A;  3BW8 A;  4TR5 A;  5D1T A;  4PKV A;  4PKW A;  1JKY A;  2C8C A;  4FML A;  4FK7 A;  1UZI A;  2WN4 A;  2C8E E;  1GXZ A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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