2WN6A

Structural basis for substrate recognition in the enzymatic component of adp-ribosyltransferase toxin cdta from clostridium difficile
Total Genus 136
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
136
sequence length
404
structure length
404
Chain Sequence
LKDKEKAKEWERKEAERIEQKLERSEKEALESYKKDSVEISKYSQTRNYFYDYQIEANSREKEYKELRNAISKNKIDKPMYVYYFESPEKFAFNKVIRTENQNEISLEKFNEFKETIQNKLFKQDGFKDISLWEPGKGDEKPTPLLMHLKLPRNTGMLPYTNTNNVSTLIEQGYSIKIDKIVRIVIDGKHYIKAEASVVSSLDFKDDVSKGDSWGKANYNDWSNKLTPNELADVNDYMRGGYTAINNYLISNGPVNNPNPELDSKITNIENALKREPIPTNLTVYRRSGPQEFGLTLTSPEYDFNKLENIDAFKSKWEGQALSYPNFISTSIGSVNMSAFAKRKIVLRITIPKGSPGAYLSAIPGYAGEYEVLLNHGSKFKINKIDSYKDGTITKLIVDATLIP
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural Basis for Substrate Recognition in the Enzymatic Component of Adp-Ribosyltransferase Toxin Cdta from Clostridium Difficile.
pubmed doi rcsb
molecule tags Transferase
source organism Clostridium difficile
molecule keywords ADP-RIBOSYLTRANSFERASE ENZYMATIC COMPONENT
total genus 136
structure length 404
sequence length 404
ec nomenclature
pdb deposition date 2009-07-07

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF03496 ADPrib_exo_Tox ADP-ribosyltransferase exoenzyme
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.176.10 Alpha Beta Alpha-Beta Complex Toxin ADP-ribosyltransferase; Chain A, domain 1 Toxin ADP-ribosyltransferase; Chain A, domain 1 2wn6A02
3.90.176.10 Alpha Beta Alpha-Beta Complex Toxin ADP-ribosyltransferase; Chain A, domain 1 Toxin ADP-ribosyltransferase; Chain A, domain 1 2wn6A01
1OG1A 4H0VA 1GXZA 4FK7A 5H04A 5GTTA 5BWMB 1QS2A 1OJZA 4GY2A 4XM6A 1PWVA 4XSHB 1OG3A 2C8HA 2C8GA 4WF6A 1GY0A 1GIRA 4PKSA 2A78B 2WN8A 2C8AA 2J3VA 1GXYA 2C8BX 4PKTA 2WN4A 1R4BA 1PWWA 1PWPA 4PKUA 4TR5A 5DZQA 4FMLA 4FXQA 4H03A 3NTSA 1GIQA 4XSGB 1GZEA 2C8FE 2A9KB 2J3XA 2WN6A 1UZIA 3U0JA 2GWMA 4PKQA 1ZXVA 1J7NA 5D1SA 1OG4A 2J3ZA 1PWQA 2C89A 5D1UA 4PKRA 4H0YA 1QS1A 1G24A 3BW8A 3BUZA 4ELNA 2BOVB 1YQYA 2C8EE 4XM8A 5H03A 5D1TA 1JKYA 4DV8A 2C8DA 2WN5A 2WN7A 1OJQA 4XM7A 1PWUA 1R45A 2C8CA 2GWLA 4PKWA 4H0XA 4PKVA 4GF1A 4H0TA 1GZFA
chains in the Genus database with same CATH superfamily
1OG1A 4H0VA 1GXZA 4FK7A 5H04A 5GTTA 5BWMB 1QS2A 1OJZA 4GY2A 4XM6A 1PWVA 4XSHB 1OG3A 2C8HA 2C8GA 4WF6A 1GY0A 1GIRA 4PKSA 2A78B 2WN8A 2C8AA 2J3VA 1GXYA 2C8BX 4PKTA 2WN4A 1R4BA 1PWWA 1PWPA 4PKUA 4TR5A 5DZQA 4FMLA 4FXQA 4H03A 3NTSA 1GIQA 4XSGB 1GZEA 2C8FE 2A9KB 2J3XA 2WN6A 1UZIA 3U0JA 2GWMA 4PKQA 1ZXVA 1J7NA 5D1SA 1OG4A 2J3ZA 1PWQA 2C89A 5D1UA 4PKRA 4H0YA 1QS1A 1G24A 3BW8A 3BUZA 4ELNA 2BOVB 1YQYA 2C8EE 4XM8A 5H03A 5D1TA 1JKYA 4DV8A 2C8DA 2WN5A 2WN7A 1OJQA 4XM7A 1PWUA 1R45A 2C8CA 2GWLA 4PKWA 4H0XA 4PKVA 4GF1A 4H0TA 1GZFA
chains in the Genus database with same CATH topology
1OG1A 4H0VA 1GXZA 4FK7A 5H04A 5GTTA 5BWMB 1QS2A 1OJZA 4GY2A 4XM6A 1PWVA 4XSHB 1OG3A 2C8HA 2C8GA 4WF6A 1GY0A 1GIRA 4PKSA 2A78B 2WN8A 2C8AA 2J3VA 1GXYA 2C8BX 4PKTA 2WN4A 1R4BA 1PWWA 1PWPA 4PKUA 4TR5A 5DZQA 4FMLA 4FXQA 4H03A 3NTSA 1GIQA 4XSGB 1GZEA 2C8FE 2A9KB 2J3XA 2WN6A 1UZIA 3U0JA 2GWMA 4PKQA 1ZXVA 1J7NA 5D1SA 1OG4A 2J3ZA 1PWQA 2C89A 5D1UA 4PKRA 4H0YA 1QS1A 1G24A 3BW8A 3BUZA 4ELNA 2BOVB 1YQYA 2C8EE 4XM8A 5H03A 5D1TA 1JKYA 4DV8A 2C8DA 2WN5A 2WN7A 1OJQA 4XM7A 1PWUA 1R45A 2C8CA 2GWLA 4PKWA 4H0XA 4PKVA 4GF1A 4H0TA 1GZFA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1OG1 A;  4H0V A;  1GXZ A;  4FK7 A;  5H04 A;  5GTT A;  5BWM B;  1QS2 A;  1OJZ A;  4GY2 A;  4XM6 A;  1PWV A;  4XSH B;  1OG3 A;  2C8H A;  2C8G A;  4WF6 A;  1GY0 A;  1GIR A;  4PKS A;  2A78 B;  2WN8 A;  2C8A A;  2J3V A;  1GXY A;  2C8B X;  4PKT A;  2WN4 A;  1R4B A;  1PWW A;  1PWP A;  4PKU A;  4TR5 A;  5DZQ A;  4FML A;  4FXQ A;  4H03 A;  3NTS A;  1GIQ A;  4XSG B;  1GZE A;  2C8F E;  2A9K B;  2J3X A;  2WN6 A;  1UZI A;  3U0J A;  2GWM A;  4PKQ A;  1ZXV A;  1J7N A;  5D1S A;  1OG4 A;  2J3Z A;  1PWQ A;  2C89 A;  5D1U A;  4PKR A;  4H0Y A;  1QS1 A;  1G24 A;  3BW8 A;  3BUZ A;  4ELN A;  2BOV B;  1YQY A;  2C8E E;  4XM8 A;  5H03 A;  5D1T A;  1JKY A;  4DV8 A;  2C8D A;  2WN5 A;  2WN7 A;  1OJQ A;  4XM7 A;  1PWU A;  1R45 A;  2C8C A;  2GWL A;  4PKW A;  4H0X A;  4PKV A;  4GF1 A;  4H0T A;  1GZF A; 
#chains in the Genus database with same CATH topology
 1OG1 A;  4H0V A;  1GXZ A;  4FK7 A;  5H04 A;  5GTT A;  5BWM B;  1QS2 A;  1OJZ A;  4GY2 A;  4XM6 A;  1PWV A;  4XSH B;  1OG3 A;  2C8H A;  2C8G A;  4WF6 A;  1GY0 A;  1GIR A;  4PKS A;  2A78 B;  2WN8 A;  2C8A A;  2J3V A;  1GXY A;  2C8B X;  4PKT A;  2WN4 A;  1R4B A;  1PWW A;  1PWP A;  4PKU A;  4TR5 A;  5DZQ A;  4FML A;  4FXQ A;  4H03 A;  3NTS A;  1GIQ A;  4XSG B;  1GZE A;  2C8F E;  2A9K B;  2J3X A;  2WN6 A;  1UZI A;  3U0J A;  2GWM A;  4PKQ A;  1ZXV A;  1J7N A;  5D1S A;  1OG4 A;  2J3Z A;  1PWQ A;  2C89 A;  5D1U A;  4PKR A;  4H0Y A;  1QS1 A;  1G24 A;  3BW8 A;  3BUZ A;  4ELN A;  2BOV B;  1YQY A;  2C8E E;  4XM8 A;  5H03 A;  5D1T A;  1JKY A;  4DV8 A;  2C8D A;  2WN5 A;  2WN7 A;  1OJQ A;  4XM7 A;  1PWU A;  1R45 A;  2C8C A;  2GWL A;  4PKW A;  4H0X A;  4PKV A;  4GF1 A;  4H0T A;  1GZF A; 
#chains in the Genus database with same CATH homology
 1OG1 A;  4H0V A;  1GXZ A;  4FK7 A;  5H04 A;  5GTT A;  5BWM B;  1QS2 A;  1OJZ A;  4GY2 A;  4XM6 A;  1PWV A;  4XSH B;  1OG3 A;  2C8H A;  2C8G A;  4WF6 A;  1GY0 A;  1GIR A;  4PKS A;  2A78 B;  2WN8 A;  2C8A A;  2J3V A;  1GXY A;  2C8B X;  4PKT A;  2WN4 A;  1R4B A;  1PWW A;  1PWP A;  4PKU A;  4TR5 A;  5DZQ A;  4FML A;  4FXQ A;  4H03 A;  3NTS A;  1GIQ A;  4XSG B;  1GZE A;  2C8F E;  2A9K B;  2J3X A;  2WN6 A;  1UZI A;  3U0J A;  2GWM A;  4PKQ A;  1ZXV A;  1J7N A;  5D1S A;  1OG4 A;  2J3Z A;  1PWQ A;  2C89 A;  5D1U A;  4PKR A;  4H0Y A;  1QS1 A;  1G24 A;  3BW8 A;  3BUZ A;  4ELN A;  2BOV B;  1YQY A;  2C8E E;  4XM8 A;  5H03 A;  5D1T A;  1JKY A;  4DV8 A;  2C8D A;  2WN5 A;  2WN7 A;  1OJQ A;  4XM7 A;  1PWU A;  1R45 A;  2C8C A;  2GWL A;  4PKW A;  4H0X A;  4PKV A;  4GF1 A;  4H0T A;  1GZF A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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