2WN8A

Structural basis for substrate recognition in the enzymatic component of adp-ribosyltransferase toxin cdta from clostridium difficile
Total Genus 125
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
125
sequence length
396
structure length
389
Chain Sequence
EWERKEAERIEQKLERSEKEALESYKKDSVEISKYSQTRNYFYDYQIEANSREKEYKELRNAISKNKIDKPMYVYYFESPEKFAFNKVIRTENQNEISLEKFNEFKETIQNKLFKQDGFKDISLYEPGKGDEKPTPLLMHLKLPRNTGMLPYTVSTLIEQGYSIKIDKIVRIVIDGKHYIKAEASVVSSLDFKDDVSKGDSWGKANYNDWSNKLTPNELADVNDYMRGGYTAINNYLISNGPVNNPNPELDSKITNIENALKREPIPTNLTVYRRSGPQEFGLTLTSPEYDFNKLENIDAFKSKWEGQALSYPNFISTSIGSVNMSAFAKRKIVLRITIPKGSPGAYLSAIPGEYEVLLNHGSKFKINKIDSYKDGTITKLIVDATLIP
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural Basis for Substrate Recognition in the Enzymatic Component of Adp-Ribosyltransferase Toxin Cdta from Clostridium Difficile.
pubmed doi rcsb
molecule tags Transferase
source organism Clostridium difficile
molecule keywords ADP-RIBOSYLTRANSFERASE ENZYMATIC COMPONENT
total genus 125
structure length 389
sequence length 396
ec nomenclature
pdb deposition date 2009-07-07

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF03496 ADPrib_exo_Tox ADP-ribosyltransferase exoenzyme
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.176.10 Alpha Beta Alpha-Beta Complex Toxin ADP-ribosyltransferase; Chain A, domain 1 Toxin ADP-ribosyltransferase; Chain A, domain 1 2wn8A02
3.90.176.10 Alpha Beta Alpha-Beta Complex Toxin ADP-ribosyltransferase; Chain A, domain 1 Toxin ADP-ribosyltransferase; Chain A, domain 1 2wn8A01
1GY0A 2C8GA 2GWLA 4H0VA 1QS1A 2WN6A 3BUZA 1YQYA 2C8FE 2C8AA 1GIQA 4PKWA 1PWPA 2WN7A 5H04A 1G24A 3U0JA 4H0YA 1QS2A 4H03A 5D1SA 4PKQA 4PKTA 2A78B 5H03A 2C8HA 1GZFA 2WN4A 4XSGB 2A9KB 2C8DA 1GXYA 1R4BA 1PWUA 2WN8A 2J3ZA 5D1UA 4PKUA 1J7NA 2BOVB 4H0XA 1OG4A 1JKYA 2WN5A 5DZQA 4WF6A 4GF1A 3NTSA 1OJZA 4XM6A 4GY2A 4XM7A 1R45A 4FMLA 2C8EE 4PKSA 2C8CA 1GZEA 2C8BX 3BW8A 1OG1A 5D1TA 1PWQA 5GTTA 1UZIA 1GXZA 4H0TA 5BWMB 1ZXVA 4FK7A 2C89A 4DV8A 1PWVA 1OJQA 4PKRA 4TR5A 2J3VA 2GWMA 4XM8A 1OG3A 4PKVA 1GIRA 4ELNA 1PWWA 4FXQA 4XSHB 2J3XA
chains in the Genus database with same CATH superfamily
1GY0A 2C8GA 2GWLA 4H0VA 1QS1A 2WN6A 3BUZA 1YQYA 2C8FE 2C8AA 1GIQA 4PKWA 1PWPA 2WN7A 5H04A 1G24A 3U0JA 4H0YA 1QS2A 4H03A 5D1SA 4PKQA 4PKTA 2A78B 5H03A 2C8HA 1GZFA 2WN4A 4XSGB 2A9KB 2C8DA 1GXYA 1R4BA 1PWUA 2WN8A 2J3ZA 5D1UA 4PKUA 1J7NA 2BOVB 4H0XA 1OG4A 1JKYA 2WN5A 5DZQA 4WF6A 4GF1A 3NTSA 1OJZA 4XM6A 4GY2A 4XM7A 1R45A 4FMLA 2C8EE 4PKSA 2C8CA 1GZEA 2C8BX 3BW8A 1OG1A 5D1TA 1PWQA 5GTTA 1UZIA 1GXZA 4H0TA 5BWMB 1ZXVA 4FK7A 2C89A 4DV8A 1PWVA 1OJQA 4PKRA 4TR5A 2J3VA 2GWMA 4XM8A 1OG3A 4PKVA 1GIRA 4ELNA 1PWWA 4FXQA 4XSHB 2J3XA
chains in the Genus database with same CATH topology
1GY0A 2C8GA 2GWLA 4H0VA 1QS1A 2WN6A 3BUZA 1YQYA 2C8FE 2C8AA 1GIQA 4PKWA 1PWPA 2WN7A 5H04A 1G24A 3U0JA 4H0YA 1QS2A 4H03A 5D1SA 4PKQA 4PKTA 2A78B 5H03A 2C8HA 1GZFA 2WN4A 4XSGB 2A9KB 2C8DA 1GXYA 1R4BA 1PWUA 2WN8A 2J3ZA 5D1UA 4PKUA 1J7NA 2BOVB 4H0XA 1OG4A 1JKYA 2WN5A 5DZQA 4WF6A 4GF1A 3NTSA 1OJZA 4XM6A 4GY2A 4XM7A 1R45A 4FMLA 2C8EE 4PKSA 2C8CA 1GZEA 2C8BX 3BW8A 1OG1A 5D1TA 1PWQA 5GTTA 1UZIA 1GXZA 4H0TA 5BWMB 1ZXVA 4FK7A 2C89A 4DV8A 1PWVA 1OJQA 4PKRA 4TR5A 2J3VA 2GWMA 4XM8A 1OG3A 4PKVA 1GIRA 4ELNA 1PWWA 4FXQA 4XSHB 2J3XA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1GY0 A;  2C8G A;  2GWL A;  4H0V A;  1QS1 A;  2WN6 A;  3BUZ A;  1YQY A;  2C8F E;  2C8A A;  1GIQ A;  4PKW A;  1PWP A;  2WN7 A;  5H04 A;  1G24 A;  3U0J A;  4H0Y A;  1QS2 A;  4H03 A;  5D1S A;  4PKQ A;  4PKT A;  2A78 B;  5H03 A;  2C8H A;  1GZF A;  2WN4 A;  4XSG B;  2A9K B;  2C8D A;  1GXY A;  1R4B A;  1PWU A;  2WN8 A;  2J3Z A;  5D1U A;  4PKU A;  1J7N A;  2BOV B;  4H0X A;  1OG4 A;  1JKY A;  2WN5 A;  5DZQ A;  4WF6 A;  4GF1 A;  3NTS A;  1OJZ A;  4XM6 A;  4GY2 A;  4XM7 A;  1R45 A;  4FML A;  2C8E E;  4PKS A;  2C8C A;  1GZE A;  2C8B X;  3BW8 A;  1OG1 A;  5D1T A;  1PWQ A;  5GTT A;  1UZI A;  1GXZ A;  4H0T A;  5BWM B;  1ZXV A;  4FK7 A;  2C89 A;  4DV8 A;  1PWV A;  1OJQ A;  4PKR A;  4TR5 A;  2J3V A;  2GWM A;  4XM8 A;  1OG3 A;  4PKV A;  1GIR A;  4ELN A;  1PWW A;  4FXQ A;  4XSH B;  2J3X A; 
#chains in the Genus database with same CATH topology
 1GY0 A;  2C8G A;  2GWL A;  4H0V A;  1QS1 A;  2WN6 A;  3BUZ A;  1YQY A;  2C8F E;  2C8A A;  1GIQ A;  4PKW A;  1PWP A;  2WN7 A;  5H04 A;  1G24 A;  3U0J A;  4H0Y A;  1QS2 A;  4H03 A;  5D1S A;  4PKQ A;  4PKT A;  2A78 B;  5H03 A;  2C8H A;  1GZF A;  2WN4 A;  4XSG B;  2A9K B;  2C8D A;  1GXY A;  1R4B A;  1PWU A;  2WN8 A;  2J3Z A;  5D1U A;  4PKU A;  1J7N A;  2BOV B;  4H0X A;  1OG4 A;  1JKY A;  2WN5 A;  5DZQ A;  4WF6 A;  4GF1 A;  3NTS A;  1OJZ A;  4XM6 A;  4GY2 A;  4XM7 A;  1R45 A;  4FML A;  2C8E E;  4PKS A;  2C8C A;  1GZE A;  2C8B X;  3BW8 A;  1OG1 A;  5D1T A;  1PWQ A;  5GTT A;  1UZI A;  1GXZ A;  4H0T A;  5BWM B;  1ZXV A;  4FK7 A;  2C89 A;  4DV8 A;  1PWV A;  1OJQ A;  4PKR A;  4TR5 A;  2J3V A;  2GWM A;  4XM8 A;  1OG3 A;  4PKV A;  1GIR A;  4ELN A;  1PWW A;  4FXQ A;  4XSH B;  2J3X A; 
#chains in the Genus database with same CATH homology
 1GY0 A;  2C8G A;  2GWL A;  4H0V A;  1QS1 A;  2WN6 A;  3BUZ A;  1YQY A;  2C8F E;  2C8A A;  1GIQ A;  4PKW A;  1PWP A;  2WN7 A;  5H04 A;  1G24 A;  3U0J A;  4H0Y A;  1QS2 A;  4H03 A;  5D1S A;  4PKQ A;  4PKT A;  2A78 B;  5H03 A;  2C8H A;  1GZF A;  2WN4 A;  4XSG B;  2A9K B;  2C8D A;  1GXY A;  1R4B A;  1PWU A;  2WN8 A;  2J3Z A;  5D1U A;  4PKU A;  1J7N A;  2BOV B;  4H0X A;  1OG4 A;  1JKY A;  2WN5 A;  5DZQ A;  4WF6 A;  4GF1 A;  3NTS A;  1OJZ A;  4XM6 A;  4GY2 A;  4XM7 A;  1R45 A;  4FML A;  2C8E E;  4PKS A;  2C8C A;  1GZE A;  2C8B X;  3BW8 A;  1OG1 A;  5D1T A;  1PWQ A;  5GTT A;  1UZI A;  1GXZ A;  4H0T A;  5BWM B;  1ZXV A;  4FK7 A;  2C89 A;  4DV8 A;  1PWV A;  1OJQ A;  4PKR A;  4TR5 A;  2J3V A;  2GWM A;  4XM8 A;  1OG3 A;  4PKV A;  1GIR A;  4ELN A;  1PWW A;  4FXQ A;  4XSH B;  2J3X A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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