3FERA

Crystal structure of n-terminal actin-binding domain from human filamin b (tandem ch-domains). northeast structural genomics consortium target hr5571a.
Total Genus 72
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
72
sequence length
239
structure length
234
Chain Sequence
PWKKIQQNTFTRWCNEHLKCVNKRIGNLQTDLSDGLRLIALLEVLSQKRMYRKYHQRPTFRQMQLENVSVALEFLDRESIKLVSIDSKAIVDGNLKLILGLVWTLILHYSISMPVWEDEGKQTPKQRLLGWIQNKIPYLPITNFNQNWQDGKALGALVDSCAPGLCPDWESWDPQKPVDNAREAMQQADDWLGVPQVITPEEIIHPDVDEHSVMTYLSQFPKAKLKPGAPLKPK
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Crystal structure of n-terminal actin-binding domain from human filamin b (tandem ch-domains). northeast structural genomics consortium target hr5571a.
rcsb
molecule tags Actin binding protein
source organism Homo sapiens
molecule keywords Filamin-B
total genus 72
structure length 234
sequence length 239
chains with identical sequence B, C, D
ec nomenclature
pdb deposition date 2008-11-30

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00307 CH Calponin homology (CH) domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.418.10 Mainly Alpha Orthogonal Bundle Actin-binding Protein, T-fimbrin; domain 1 Calponin-like domain 3ferA01
1.10.418.10 Mainly Alpha Orthogonal Bundle Actin-binding Protein, T-fimbrin; domain 1 Calponin-like domain 3ferA02
2D87A 3I6XA 1WYLA 1P5SA 1BHDA 2YRNA 2D88A 5A36A 1UEGA 1RT8A 1TJTA 2DK9A 2R0OA 3JARM 2WA5A 2WA6A 1P2XA 3JAKM 2R8UA 2E9KA 3HORA 2VZGB 1SH5A 3F7PA 1UJOA 4Q57B 2VZCA 2VZDA 5BVRA 2D85A 2VZIB 4EDNA 2EYIA 5L0OA 1WYNA 4B7LA 5A38A 5A4BA 1VKAA 1H67A 1WYMA 4TXKA 3REPB 1AOAA 2EE7A 3KMUB 3FERA 1WJOA 5A37A 1PA7A 4EDLA 1WYPA 1MB8A 2K3SA 1WIXA 3CO1A 2QJXA 1V5KA 3JALM 2WA7A 2D89A 3HOCA 1WKUA 2EYNA 4EDMA 2JV9A 2QJZA 5J8EA 1WYRA 1QAGA 1BKRA 3HOPA 4Q59A 4Q58A 4TXIA 1WYOA 1PXYA 2L3GA 1DXXA 1AA2A 3KMWB 2RR8A 3KY9A 2K2RA 1WYQA 2WFNA 1SH6A 2D86A
chains in the Genus database with same CATH superfamily
5FMTA 2D87A 3I6XA 1WYLA 1P5SA 1BHDA 2YRNA 2D88A 5A36A 1UEGA 1RT8A 1TJTA 2DK9A 2R0OA 3JARM 2WA5A 2WA6A 1P2XA 3JAKM 2R8UA 3EAYA 2E9KA 3HORA 2VZGB 1SH5A 3F7PA 1UJOA 4Q57B 2VZCA 2VZDA 5BVRA 4LVRA 2D85A 4DDPA 2VZIB 2IGPA 4EDNA 2EYIA 2VE7A 5L0OA 2EQOA 1WYNA 4B7LA 5A38A 5A4BA 1VKAA 1H67A 1WYMA 4TXKA 2WDTA 3REPB 1AOAA 2EE7A 3KMUB 2HL9A 3FERA 3VP7A 5FMUA 1WJOA 5A37A 1PA7A 2HL8A 4EDLA 1WYPA 1MB8A 2K3SA 1WIXA 3CO1A 2QJXA 1V5KA 3JALM 2WA7A 2D89A 3HOCA 1WKUA 2EYNA 4EDMA 2VE7C 2JV9A 2QJZA 1EUVA 5J8EA 1WYRA 1QAGA 1BKRA 2WE6A 4LVPA 3HOPA 2HKPA 4Q59A 4Q58A 4TXIA 1WYOA 1PXYA 2L3GA 1DXXA 1AA2A 3KMWB 2RR8A 3KY9A 2K2RA 1WYQA 2WFNA 1SH6A 2D86A
chains in the Genus database with same CATH topology
2D87A 3I6XA 1WYLA 1P5SA 1BHDA 2YRNA 2D88A 5A36A 1UEGA 1RT8A 1TJTA 2DK9A 2R0OA 3JARM 2WA5A 2WA6A 1P2XA 3JAKM 2R8UA 2E9KA 3HORA 2VZGB 1SH5A 3F7PA 1UJOA 4Q57B 2VZCA 2VZDA 5BVRA 2D85A 2VZIB 4EDNA 2EYIA 5L0OA 1WYNA 4B7LA 5A38A 5A4BA 1VKAA 1H67A 1WYMA 4TXKA 3REPB 1AOAA 2EE7A 3KMUB 3FERA 1WJOA 5A37A 1PA7A 4EDLA 1WYPA 1MB8A 2K3SA 1WIXA 3CO1A 2QJXA 1V5KA 3JALM 2WA7A 2D89A 3HOCA 1WKUA 2EYNA 4EDMA 2JV9A 2QJZA 5J8EA 1WYRA 1QAGA 1BKRA 3HOPA 4Q59A 4Q58A 4TXIA 1WYOA 1PXYA 2L3GA 1DXXA 1AA2A 3KMWB 2RR8A 3KY9A 2K2RA 1WYQA 2WFNA 1SH6A 2D86A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2D87 A;  3I6X A;  1WYL A;  1P5S A;  1BHD A;  2YRN A;  2D88 A;  5A36 A;  1UEG A;  1RT8 A;  1TJT A;  2DK9 A;  2R0O A;  3JAR M;  2WA5 A;  2WA6 A;  1P2X A;  3JAK M;  2R8U A;  2E9K A;  3HOR A;  2VZG B;  1SH5 A;  3F7P A;  1UJO A;  4Q57 B;  2VZC A;  2VZD A;  5BVR A;  2D85 A;  2VZI B;  4EDN A;  2EYI A;  5L0O A;  1WYN A;  4B7L A;  5A38 A;  5A4B A;  1VKA A;  1H67 A;  1WYM A;  4TXK A;  3REP B;  1AOA A;  2EE7 A;  3KMU B;  3FER A;  1WJO A;  5A37 A;  1PA7 A;  4EDL A;  1WYP A;  1MB8 A;  2K3S A;  1WIX A;  3CO1 A;  2QJX A;  1V5K A;  3JAL M;  2WA7 A;  2D89 A;  3HOC A;  1WKU A;  2EYN A;  4EDM A;  2JV9 A;  2QJZ A;  5J8E A;  1WYR A;  1QAG A;  1BKR A;  3HOP A;  4Q59 A;  4Q58 A;  4TXI A;  1WYO A;  1PXY A;  2L3G A;  1DXX A;  1AA2 A;  3KMW B;  2RR8 A;  3KY9 A;  2K2R A;  1WYQ A;  2WFN A;  1SH6 A;  2D86 A; 
#chains in the Genus database with same CATH topology
 5FMT A;  2D87 A;  3I6X A;  1WYL A;  1P5S A;  1BHD A;  2YRN A;  2D88 A;  5A36 A;  1UEG A;  1RT8 A;  1TJT A;  2DK9 A;  2R0O A;  3JAR M;  2WA5 A;  2WA6 A;  1P2X A;  3JAK M;  2R8U A;  3EAY A;  2E9K A;  3HOR A;  2VZG B;  1SH5 A;  3F7P A;  1UJO A;  4Q57 B;  2VZC A;  2VZD A;  5BVR A;  4LVR A;  2D85 A;  4DDP A;  2VZI B;  2IGP A;  4EDN A;  2EYI A;  2VE7 A;  5L0O A;  2EQO A;  1WYN A;  4B7L A;  5A38 A;  5A4B A;  1VKA A;  1H67 A;  1WYM A;  4TXK A;  2WDT A;  3REP B;  1AOA A;  2EE7 A;  3KMU B;  2HL9 A;  3FER A;  3VP7 A;  5FMU A;  1WJO A;  5A37 A;  1PA7 A;  2HL8 A;  4EDL A;  1WYP A;  1MB8 A;  2K3S A;  1WIX A;  3CO1 A;  2QJX A;  1V5K A;  3JAL M;  2WA7 A;  2D89 A;  3HOC A;  1WKU A;  2EYN A;  4EDM A;  2VE7 C;  2JV9 A;  2QJZ A;  1EUV A;  5J8E A;  1WYR A;  1QAG A;  1BKR A;  2WE6 A;  4LVP A;  3HOP A;  2HKP A;  4Q59 A;  4Q58 A;  4TXI A;  1WYO A;  1PXY A;  2L3G A;  1DXX A;  1AA2 A;  3KMW B;  2RR8 A;  3KY9 A;  2K2R A;  1WYQ A;  2WFN A;  1SH6 A;  2D86 A; 
#chains in the Genus database with same CATH homology
 2D87 A;  3I6X A;  1WYL A;  1P5S A;  1BHD A;  2YRN A;  2D88 A;  5A36 A;  1UEG A;  1RT8 A;  1TJT A;  2DK9 A;  2R0O A;  3JAR M;  2WA5 A;  2WA6 A;  1P2X A;  3JAK M;  2R8U A;  2E9K A;  3HOR A;  2VZG B;  1SH5 A;  3F7P A;  1UJO A;  4Q57 B;  2VZC A;  2VZD A;  5BVR A;  2D85 A;  2VZI B;  4EDN A;  2EYI A;  5L0O A;  1WYN A;  4B7L A;  5A38 A;  5A4B A;  1VKA A;  1H67 A;  1WYM A;  4TXK A;  3REP B;  1AOA A;  2EE7 A;  3KMU B;  3FER A;  1WJO A;  5A37 A;  1PA7 A;  4EDL A;  1WYP A;  1MB8 A;  2K3S A;  1WIX A;  3CO1 A;  2QJX A;  1V5K A;  3JAL M;  2WA7 A;  2D89 A;  3HOC A;  1WKU A;  2EYN A;  4EDM A;  2JV9 A;  2QJZ A;  5J8E A;  1WYR A;  1QAG A;  1BKR A;  3HOP A;  4Q59 A;  4Q58 A;  4TXI A;  1WYO A;  1PXY A;  2L3G A;  1DXX A;  1AA2 A;  3KMW B;  2RR8 A;  3KY9 A;  2K2R A;  1WYQ A;  2WFN A;  1SH6 A;  2D86 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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