3JAKM

Cryo-em structure of gtpgammas-microtubule co-polymerized with eb3 (merged dataset with and without kinesin bound)
Total Genus 34
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
34
sequence length
131
structure length
131
Chain Sequence
MAVNVYSTSVTSENLSRHDMLAWVNDSLHLNYTKIEQLCSGAAYCQFMDMLFPGCVHLRKVKFQAKLEHEYIHNFKVLQAAFKKMGVDKIIPVEKLVKGKFQDNFEFIQWFKKFFDANYDGKDYNPLLARQ
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Mechanistic Origin of Microtubule Dynamic Instability and Its Modulation by EB Proteins.
pubmed doi rcsb
molecule tags Structural protein
source organism Homo sapiens
molecule keywords Tubulin alpha-1B chain
total genus 34
structure length 131
sequence length 131
chains with identical sequence N
ec nomenclature
pdb deposition date 2015-06-16

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
M PF00307 CH Calponin homology (CH) domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.418.10 Mainly Alpha Orthogonal Bundle Actin-binding Protein, T-fimbrin; domain 1 Calponin-like domain 3jakM00
5A36A 2K3SA 1UEGA 2VZDA 3FERA 1WYNA 2E9KA 1WYOA 3I6XA 1AA2A 2D89A 1WYQA 4TXIA 2R8UA 2VZIB 1VKAA 3KMWB 2EYIA 1WYPA 4EDMA 1AOAA 1QAGA 2WA5A 3JARM 1WYLA 5A38A 2QJZA 4TXKA 3JAKM 2D86A 1P2XA 2RR8A 2L3GA 4Q58A 1TJTA 4EDNA 1PA7A 3KY9A 3KMUB 5L0OA 4EDLA 3HOPA 2VZCA 5BVRA 1V5KA 2WA7A 1RT8A 3HORA 2R0OA 2EYNA 1P5SA 3CO1A 1WKUA 4Q59A 2JV9A 3F7PA 2DK9A 5A4BA 2WFNA 5A37A 4B7LA 1BHDA 2WA6A 1WYMA 2K2RA 1H67A 1WJOA 1MB8A 2YRNA 5J8EA 1DXXA 3HOCA 1WYRA 2D88A 1UJOA 4Q57B 2D87A 2VZGB 2EE7A 1PXYA 1BKRA 1SH5A 1WIXA 2D85A 3JALM 2QJXA 3REPB 1SH6A
chains in the Genus database with same CATH superfamily
5A36A 4DDPA 2K3SA 5FMUA 1UEGA 4LVRA 2VZDA 3FERA 2VE7C 1WYNA 2E9KA 1WYOA 3I6XA 1AA2A 2D89A 1WYQA 4TXIA 2R8UA 2VZIB 1VKAA 3KMWB 2EYIA 1WYPA 4EDMA 1AOAA 1QAGA 2WA5A 3JARM 5FMTA 1WYLA 5A38A 2QJZA 2HL8A 4TXKA 3JAKM 2D86A 1P2XA 2HL9A 2RR8A 2L3GA 4Q58A 1TJTA 3EAYA 4EDNA 3VP7A 1PA7A 2WDTA 3KY9A 3KMUB 5L0OA 4EDLA 2WE6A 3HOPA 2VZCA 5BVRA 2EQOA 1V5KA 2WA7A 2HKPA 1RT8A 1EUVA 3HORA 2R0OA 2EYNA 1P5SA 3CO1A 2VE7A 1WKUA 4Q59A 2JV9A 3F7PA 2DK9A 5A4BA 2WFNA 5A37A 4B7LA 4LVPA 1BHDA 2WA6A 2IGPA 1WYMA 2K2RA 1H67A 1WJOA 1MB8A 2YRNA 5J8EA 1DXXA 3HOCA 1WYRA 2D88A 1UJOA 4Q57B 2D87A 2VZGB 2EE7A 1PXYA 1BKRA 1SH5A 1WIXA 2D85A 3JALM 2QJXA 3REPB 1SH6A
chains in the Genus database with same CATH topology
5A36A 2K3SA 1UEGA 2VZDA 3FERA 1WYNA 2E9KA 1WYOA 3I6XA 1AA2A 2D89A 1WYQA 4TXIA 2R8UA 2VZIB 1VKAA 3KMWB 2EYIA 1WYPA 4EDMA 1AOAA 1QAGA 2WA5A 3JARM 1WYLA 5A38A 2QJZA 4TXKA 3JAKM 2D86A 1P2XA 2RR8A 2L3GA 4Q58A 1TJTA 4EDNA 1PA7A 3KY9A 3KMUB 5L0OA 4EDLA 3HOPA 2VZCA 5BVRA 1V5KA 2WA7A 1RT8A 3HORA 2R0OA 2EYNA 1P5SA 3CO1A 1WKUA 4Q59A 2JV9A 3F7PA 2DK9A 5A4BA 2WFNA 5A37A 4B7LA 1BHDA 2WA6A 1WYMA 2K2RA 1H67A 1WJOA 1MB8A 2YRNA 5J8EA 1DXXA 3HOCA 1WYRA 2D88A 1UJOA 4Q57B 2D87A 2VZGB 2EE7A 1PXYA 1BKRA 1SH5A 1WIXA 2D85A 3JALM 2QJXA 3REPB 1SH6A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 5A36 A;  2K3S A;  1UEG A;  2VZD A;  3FER A;  1WYN A;  2E9K A;  1WYO A;  3I6X A;  1AA2 A;  2D89 A;  1WYQ A;  4TXI A;  2R8U A;  2VZI B;  1VKA A;  3KMW B;  2EYI A;  1WYP A;  4EDM A;  1AOA A;  1QAG A;  2WA5 A;  3JAR M;  1WYL A;  5A38 A;  2QJZ A;  4TXK A;  3JAK M;  2D86 A;  1P2X A;  2RR8 A;  2L3G A;  4Q58 A;  1TJT A;  4EDN A;  1PA7 A;  3KY9 A;  3KMU B;  5L0O A;  4EDL A;  3HOP A;  2VZC A;  5BVR A;  1V5K A;  2WA7 A;  1RT8 A;  3HOR A;  2R0O A;  2EYN A;  1P5S A;  3CO1 A;  1WKU A;  4Q59 A;  2JV9 A;  3F7P A;  2DK9 A;  5A4B A;  2WFN A;  5A37 A;  4B7L A;  1BHD A;  2WA6 A;  1WYM A;  2K2R A;  1H67 A;  1WJO A;  1MB8 A;  2YRN A;  5J8E A;  1DXX A;  3HOC A;  1WYR A;  2D88 A;  1UJO A;  4Q57 B;  2D87 A;  2VZG B;  2EE7 A;  1PXY A;  1BKR A;  1SH5 A;  1WIX A;  2D85 A;  3JAL M;  2QJX A;  3REP B;  1SH6 A; 
#chains in the Genus database with same CATH topology
 5A36 A;  4DDP A;  2K3S A;  5FMU A;  1UEG A;  4LVR A;  2VZD A;  3FER A;  2VE7 C;  1WYN A;  2E9K A;  1WYO A;  3I6X A;  1AA2 A;  2D89 A;  1WYQ A;  4TXI A;  2R8U A;  2VZI B;  1VKA A;  3KMW B;  2EYI A;  1WYP A;  4EDM A;  1AOA A;  1QAG A;  2WA5 A;  3JAR M;  5FMT A;  1WYL A;  5A38 A;  2QJZ A;  2HL8 A;  4TXK A;  3JAK M;  2D86 A;  1P2X A;  2HL9 A;  2RR8 A;  2L3G A;  4Q58 A;  1TJT A;  3EAY A;  4EDN A;  3VP7 A;  1PA7 A;  2WDT A;  3KY9 A;  3KMU B;  5L0O A;  4EDL A;  2WE6 A;  3HOP A;  2VZC A;  5BVR A;  2EQO A;  1V5K A;  2WA7 A;  2HKP A;  1RT8 A;  1EUV A;  3HOR A;  2R0O A;  2EYN A;  1P5S A;  3CO1 A;  2VE7 A;  1WKU A;  4Q59 A;  2JV9 A;  3F7P A;  2DK9 A;  5A4B A;  2WFN A;  5A37 A;  4B7L A;  4LVP A;  1BHD A;  2WA6 A;  2IGP A;  1WYM A;  2K2R A;  1H67 A;  1WJO A;  1MB8 A;  2YRN A;  5J8E A;  1DXX A;  3HOC A;  1WYR A;  2D88 A;  1UJO A;  4Q57 B;  2D87 A;  2VZG B;  2EE7 A;  1PXY A;  1BKR A;  1SH5 A;  1WIX A;  2D85 A;  3JAL M;  2QJX A;  3REP B;  1SH6 A; 
#chains in the Genus database with same CATH homology
 5A36 A;  2K3S A;  1UEG A;  2VZD A;  3FER A;  1WYN A;  2E9K A;  1WYO A;  3I6X A;  1AA2 A;  2D89 A;  1WYQ A;  4TXI A;  2R8U A;  2VZI B;  1VKA A;  3KMW B;  2EYI A;  1WYP A;  4EDM A;  1AOA A;  1QAG A;  2WA5 A;  3JAR M;  1WYL A;  5A38 A;  2QJZ A;  4TXK A;  3JAK M;  2D86 A;  1P2X A;  2RR8 A;  2L3G A;  4Q58 A;  1TJT A;  4EDN A;  1PA7 A;  3KY9 A;  3KMU B;  5L0O A;  4EDL A;  3HOP A;  2VZC A;  5BVR A;  1V5K A;  2WA7 A;  1RT8 A;  3HOR A;  2R0O A;  2EYN A;  1P5S A;  3CO1 A;  1WKU A;  4Q59 A;  2JV9 A;  3F7P A;  2DK9 A;  5A4B A;  2WFN A;  5A37 A;  4B7L A;  1BHD A;  2WA6 A;  1WYM A;  2K2R A;  1H67 A;  1WJO A;  1MB8 A;  2YRN A;  5J8E A;  1DXX A;  3HOC A;  1WYR A;  2D88 A;  1UJO A;  4Q57 B;  2D87 A;  2VZG B;  2EE7 A;  1PXY A;  1BKR A;  1SH5 A;  1WIX A;  2D85 A;  3JAL M;  2QJX A;  3REP B;  1SH6 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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