3JARM

Cryo-em structure of gdp-microtubule co-polymerized with eb3
Total Genus 33
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
33
sequence length
131
structure length
131
Chain Sequence
MAVNVYSTSVTSENLSRHDMLAWVNDSLHLNYTKIEQLCSGAAYCQFMDMLFPGCVHLRKVKFQAKLEHEYIHNFKVLQAAFKKMGVDKIIPVEKLVKGKFQDNFEFIQWFKKFFDANYDGKDYNPLLARQ
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Mechanistic Origin of Microtubule Dynamic Instability and Its Modulation by EB Proteins.
pubmed doi rcsb
molecule tags Structural protein
source organism Homo sapiens
molecule keywords Tubulin alpha-1B chain
total genus 33
structure length 131
sequence length 131
chains with identical sequence N
ec nomenclature
pdb deposition date 2015-06-19

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
M PF00307 CH Calponin homology (CH) domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.418.10 Mainly Alpha Orthogonal Bundle Actin-binding Protein, T-fimbrin; domain 1 Calponin-like domain 3jarM00
1QAGA 2L3GA 5BVRA 5A4BA 1WYLA 1TJTA 2QJZA 2WFNA 4Q59A 2EYNA 5A37A 2VZGB 4Q58A 2VZDA 2E9KA 2K2RA 2WA7A 3FERA 2R0OA 4TXIA 3CO1A 1RT8A 3HOPA 2WA5A 4TXKA 3JAKM 2K3SA 3F7PA 4EDNA 1P2XA 1VKAA 5J8EA 1PA7A 1UJOA 2VZCA 3JARM 1AOAA 1PXYA 4B7LA 2D86A 1WYPA 2JV9A 1BKRA 5A38A 2RR8A 1WYOA 2VZIB 1MB8A 1WIXA 1WYQA 1WYRA 3HORA 1WJOA 3JALM 3KMWB 5A36A 1SH5A 2EYIA 5L0OA 4EDMA 1SH6A 1WYMA 4EDLA 1BHDA 2YRNA 3KMUB 2R8UA 2WA6A 3HOCA 2D85A 2D89A 3KY9A 1H67A 1WKUA 1AA2A 2D88A 3REPB 3I6XA 2EE7A 1UEGA 2D87A 1DXXA 1V5KA 1P5SA 1WYNA 2DK9A 2QJXA 4Q57B
chains in the Genus database with same CATH superfamily
1QAGA 2HKPA 2L3GA 3VP7A 5BVRA 2VE7A 5A4BA 1WYLA 1TJTA 2QJZA 2WFNA 4Q59A 2HL8A 4LVPA 2EYNA 5A37A 2VZGB 4Q58A 2VZDA 2E9KA 2K2RA 2WA7A 3FERA 2R0OA 4TXIA 3CO1A 1RT8A 3HOPA 2WA5A 4TXKA 3JAKM 2WDTA 2K3SA 3F7PA 4EDNA 1P2XA 1EUVA 1VKAA 5J8EA 1PA7A 1UJOA 2VZCA 3JARM 1AOAA 5FMUA 1PXYA 4B7LA 2D86A 1WYPA 2JV9A 1BKRA 5A38A 2RR8A 1WYOA 2VZIB 1MB8A 1WIXA 3EAYA 1WYQA 1WYRA 3HORA 2HL9A 1WJOA 3JALM 3KMWB 5A36A 1SH5A 2EYIA 5L0OA 4EDMA 1SH6A 1WYMA 4EDLA 1BHDA 2YRNA 3KMUB 2R8UA 2WA6A 3HOCA 2D85A 2D89A 3KY9A 5FMTA 2WE6A 1H67A 2IGPA 1WKUA 1AA2A 2EQOA 2D88A 3REPB 3I6XA 2EE7A 4LVRA 1UEGA 2D87A 1DXXA 1V5KA 1P5SA 4DDPA 1WYNA 2DK9A 2QJXA 4Q57B 2VE7C
chains in the Genus database with same CATH topology
1QAGA 2L3GA 5BVRA 5A4BA 1WYLA 1TJTA 2QJZA 2WFNA 4Q59A 2EYNA 5A37A 2VZGB 4Q58A 2VZDA 2E9KA 2K2RA 2WA7A 3FERA 2R0OA 4TXIA 3CO1A 1RT8A 3HOPA 2WA5A 4TXKA 3JAKM 2K3SA 3F7PA 4EDNA 1P2XA 1VKAA 5J8EA 1PA7A 1UJOA 2VZCA 3JARM 1AOAA 1PXYA 4B7LA 2D86A 1WYPA 2JV9A 1BKRA 5A38A 2RR8A 1WYOA 2VZIB 1MB8A 1WIXA 1WYQA 1WYRA 3HORA 1WJOA 3JALM 3KMWB 5A36A 1SH5A 2EYIA 5L0OA 4EDMA 1SH6A 1WYMA 4EDLA 1BHDA 2YRNA 3KMUB 2R8UA 2WA6A 3HOCA 2D85A 2D89A 3KY9A 1H67A 1WKUA 1AA2A 2D88A 3REPB 3I6XA 2EE7A 1UEGA 2D87A 1DXXA 1V5KA 1P5SA 1WYNA 2DK9A 2QJXA 4Q57B
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1QAG A;  2L3G A;  5BVR A;  5A4B A;  1WYL A;  1TJT A;  2QJZ A;  2WFN A;  4Q59 A;  2EYN A;  5A37 A;  2VZG B;  4Q58 A;  2VZD A;  2E9K A;  2K2R A;  2WA7 A;  3FER A;  2R0O A;  4TXI A;  3CO1 A;  1RT8 A;  3HOP A;  2WA5 A;  4TXK A;  3JAK M;  2K3S A;  3F7P A;  4EDN A;  1P2X A;  1VKA A;  5J8E A;  1PA7 A;  1UJO A;  2VZC A;  3JAR M;  1AOA A;  1PXY A;  4B7L A;  2D86 A;  1WYP A;  2JV9 A;  1BKR A;  5A38 A;  2RR8 A;  1WYO A;  2VZI B;  1MB8 A;  1WIX A;  1WYQ A;  1WYR A;  3HOR A;  1WJO A;  3JAL M;  3KMW B;  5A36 A;  1SH5 A;  2EYI A;  5L0O A;  4EDM A;  1SH6 A;  1WYM A;  4EDL A;  1BHD A;  2YRN A;  3KMU B;  2R8U A;  2WA6 A;  3HOC A;  2D85 A;  2D89 A;  3KY9 A;  1H67 A;  1WKU A;  1AA2 A;  2D88 A;  3REP B;  3I6X A;  2EE7 A;  1UEG A;  2D87 A;  1DXX A;  1V5K A;  1P5S A;  1WYN A;  2DK9 A;  2QJX A;  4Q57 B; 
#chains in the Genus database with same CATH topology
 1QAG A;  2HKP A;  2L3G A;  3VP7 A;  5BVR A;  2VE7 A;  5A4B A;  1WYL A;  1TJT A;  2QJZ A;  2WFN A;  4Q59 A;  2HL8 A;  4LVP A;  2EYN A;  5A37 A;  2VZG B;  4Q58 A;  2VZD A;  2E9K A;  2K2R A;  2WA7 A;  3FER A;  2R0O A;  4TXI A;  3CO1 A;  1RT8 A;  3HOP A;  2WA5 A;  4TXK A;  3JAK M;  2WDT A;  2K3S A;  3F7P A;  4EDN A;  1P2X A;  1EUV A;  1VKA A;  5J8E A;  1PA7 A;  1UJO A;  2VZC A;  3JAR M;  1AOA A;  5FMU A;  1PXY A;  4B7L A;  2D86 A;  1WYP A;  2JV9 A;  1BKR A;  5A38 A;  2RR8 A;  1WYO A;  2VZI B;  1MB8 A;  1WIX A;  3EAY A;  1WYQ A;  1WYR A;  3HOR A;  2HL9 A;  1WJO A;  3JAL M;  3KMW B;  5A36 A;  1SH5 A;  2EYI A;  5L0O A;  4EDM A;  1SH6 A;  1WYM A;  4EDL A;  1BHD A;  2YRN A;  3KMU B;  2R8U A;  2WA6 A;  3HOC A;  2D85 A;  2D89 A;  3KY9 A;  5FMT A;  2WE6 A;  1H67 A;  2IGP A;  1WKU A;  1AA2 A;  2EQO A;  2D88 A;  3REP B;  3I6X A;  2EE7 A;  4LVR A;  1UEG A;  2D87 A;  1DXX A;  1V5K A;  1P5S A;  4DDP A;  1WYN A;  2DK9 A;  2QJX A;  4Q57 B;  2VE7 C; 
#chains in the Genus database with same CATH homology
 1QAG A;  2L3G A;  5BVR A;  5A4B A;  1WYL A;  1TJT A;  2QJZ A;  2WFN A;  4Q59 A;  2EYN A;  5A37 A;  2VZG B;  4Q58 A;  2VZD A;  2E9K A;  2K2R A;  2WA7 A;  3FER A;  2R0O A;  4TXI A;  3CO1 A;  1RT8 A;  3HOP A;  2WA5 A;  4TXK A;  3JAK M;  2K3S A;  3F7P A;  4EDN A;  1P2X A;  1VKA A;  5J8E A;  1PA7 A;  1UJO A;  2VZC A;  3JAR M;  1AOA A;  1PXY A;  4B7L A;  2D86 A;  1WYP A;  2JV9 A;  1BKR A;  5A38 A;  2RR8 A;  1WYO A;  2VZI B;  1MB8 A;  1WIX A;  1WYQ A;  1WYR A;  3HOR A;  1WJO A;  3JAL M;  3KMW B;  5A36 A;  1SH5 A;  2EYI A;  5L0O A;  4EDM A;  1SH6 A;  1WYM A;  4EDL A;  1BHD A;  2YRN A;  3KMU B;  2R8U A;  2WA6 A;  3HOC A;  2D85 A;  2D89 A;  3KY9 A;  1H67 A;  1WKU A;  1AA2 A;  2D88 A;  3REP B;  3I6X A;  2EE7 A;  1UEG A;  2D87 A;  1DXX A;  1V5K A;  1P5S A;  1WYN A;  2DK9 A;  2QJX A;  4Q57 B; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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