3KMUB

Crystal structure of the ilk/alpha-parvin core complex (apo)
Total Genus 35
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
35
sequence length
124
structure length
124
Chain Sequence
AFDTLFDHAPDKLNVVKKTLITFVNKHLNKLNLEVTELETQFADGVYLVLLMGLLEGYFVPLHSFFLTPDSFEQKVLNVSFAFELMQDGGLEKPKPRPEDIVNCDLKSTLRVLYNLFTKYRNVE
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title The pseudoactive site of ILK is essential for its binding to alpha-Parvin and localization to focal adhesions.
pubmed doi rcsb
molecule tags Cell adhesion
source organism Homo sapiens
molecule keywords Integrin-linked kinase
total genus 35
structure length 124
sequence length 124
ec nomenclature
pdb deposition date 2009-11-11

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
B PF00307 CH Calponin homology (CH) domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.418.10 Mainly Alpha Orthogonal Bundle Actin-binding Protein, T-fimbrin; domain 1 Calponin-like domain 3kmuB00
1P5SA 5L0OA 1WKUA 5A38A 2VZIB 5A4BA 2K3SA 1AOAA 4TXKA 2JV9A 2WA5A 1AA2A 2D86A 5BVRA 1WYRA 3HORA 4EDMA 2RR8A 1MB8A 1WYMA 4Q58A 2EE7A 1BHDA 1WYLA 1WIXA 2D88A 2QJXA 2R0OA 2D89A 1V5KA 2VZGB 1QAGA 1WYPA 4Q57B 2WFNA 5A37A 2WA7A 3CO1A 1BKRA 3REPB 1PA7A 2WA6A 1SH6A 2E9KA 3F7PA 2EYIA 4B7LA 3I6XA 3KMUB 3JAKM 1WJOA 1H67A 2K2RA 2YRNA 2DK9A 4TXIA 2D87A 4Q59A 2D85A 1TJTA 3KY9A 3HOPA 5A36A 3FERA 1UJOA 2VZDA 1WYOA 4EDLA 2R8UA 1PXYA 1SH5A 3JARM 2L3GA 4EDNA 3KMWB 1DXXA 2QJZA 3HOCA 2EYNA 1WYNA 1RT8A 1VKAA 2VZCA 1WYQA 1UEGA 1P2XA 3JALM 5J8EA
chains in the Genus database with same CATH superfamily
1P5SA 5L0OA 1WKUA 5A38A 2VZIB 5A4BA 2K3SA 4LVPA 1AOAA 4TXKA 2JV9A 2WA5A 1AA2A 2D86A 5BVRA 2WDTA 1WYRA 3HORA 4EDMA 2RR8A 3VP7A 1MB8A 1WYMA 4DDPA 4Q58A 2EE7A 1BHDA 1WYLA 1WIXA 2D88A 2QJXA 2R0OA 1EUVA 3EAYA 2D89A 1V5KA 2VZGB 1QAGA 5FMUA 1WYPA 4Q57B 2WFNA 5A37A 2WA7A 3CO1A 1BKRA 2HKPA 3REPB 1PA7A 2WA6A 1SH6A 2E9KA 3F7PA 2EYIA 4B7LA 3I6XA 3KMUB 3JAKM 1WJOA 1H67A 2K2RA 2IGPA 2YRNA 2DK9A 4TXIA 2D87A 2EQOA 4Q59A 2D85A 1TJTA 3KY9A 2HL8A 3HOPA 2VE7A 5A36A 3FERA 1UJOA 4LVRA 2VZDA 1WYOA 4EDLA 2R8UA 1PXYA 1SH5A 3JARM 2HL9A 2L3GA 4EDNA 5FMTA 3KMWB 1DXXA 2QJZA 3HOCA 2EYNA 1WYNA 1RT8A 1VKAA 2VZCA 1WYQA 1UEGA 1P2XA 3JALM 2WE6A 2VE7C 5J8EA
chains in the Genus database with same CATH topology
1P5SA 5L0OA 1WKUA 5A38A 2VZIB 5A4BA 2K3SA 1AOAA 4TXKA 2JV9A 2WA5A 1AA2A 2D86A 5BVRA 1WYRA 3HORA 4EDMA 2RR8A 1MB8A 1WYMA 4Q58A 2EE7A 1BHDA 1WYLA 1WIXA 2D88A 2QJXA 2R0OA 2D89A 1V5KA 2VZGB 1QAGA 1WYPA 4Q57B 2WFNA 5A37A 2WA7A 3CO1A 1BKRA 3REPB 1PA7A 2WA6A 1SH6A 2E9KA 3F7PA 2EYIA 4B7LA 3I6XA 3KMUB 3JAKM 1WJOA 1H67A 2K2RA 2YRNA 2DK9A 4TXIA 2D87A 4Q59A 2D85A 1TJTA 3KY9A 3HOPA 5A36A 3FERA 1UJOA 2VZDA 1WYOA 4EDLA 2R8UA 1PXYA 1SH5A 3JARM 2L3GA 4EDNA 3KMWB 1DXXA 2QJZA 3HOCA 2EYNA 1WYNA 1RT8A 1VKAA 2VZCA 1WYQA 1UEGA 1P2XA 3JALM 5J8EA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1P5S A;  5L0O A;  1WKU A;  5A38 A;  2VZI B;  5A4B A;  2K3S A;  1AOA A;  4TXK A;  2JV9 A;  2WA5 A;  1AA2 A;  2D86 A;  5BVR A;  1WYR A;  3HOR A;  4EDM A;  2RR8 A;  1MB8 A;  1WYM A;  4Q58 A;  2EE7 A;  1BHD A;  1WYL A;  1WIX A;  2D88 A;  2QJX A;  2R0O A;  2D89 A;  1V5K A;  2VZG B;  1QAG A;  1WYP A;  4Q57 B;  2WFN A;  5A37 A;  2WA7 A;  3CO1 A;  1BKR A;  3REP B;  1PA7 A;  2WA6 A;  1SH6 A;  2E9K A;  3F7P A;  2EYI A;  4B7L A;  3I6X A;  3KMU B;  3JAK M;  1WJO A;  1H67 A;  2K2R A;  2YRN A;  2DK9 A;  4TXI A;  2D87 A;  4Q59 A;  2D85 A;  1TJT A;  3KY9 A;  3HOP A;  5A36 A;  3FER A;  1UJO A;  2VZD A;  1WYO A;  4EDL A;  2R8U A;  1PXY A;  1SH5 A;  3JAR M;  2L3G A;  4EDN A;  3KMW B;  1DXX A;  2QJZ A;  3HOC A;  2EYN A;  1WYN A;  1RT8 A;  1VKA A;  2VZC A;  1WYQ A;  1UEG A;  1P2X A;  3JAL M;  5J8E A; 
#chains in the Genus database with same CATH topology
 1P5S A;  5L0O A;  1WKU A;  5A38 A;  2VZI B;  5A4B A;  2K3S A;  4LVP A;  1AOA A;  4TXK A;  2JV9 A;  2WA5 A;  1AA2 A;  2D86 A;  5BVR A;  2WDT A;  1WYR A;  3HOR A;  4EDM A;  2RR8 A;  3VP7 A;  1MB8 A;  1WYM A;  4DDP A;  4Q58 A;  2EE7 A;  1BHD A;  1WYL A;  1WIX A;  2D88 A;  2QJX A;  2R0O A;  1EUV A;  3EAY A;  2D89 A;  1V5K A;  2VZG B;  1QAG A;  5FMU A;  1WYP A;  4Q57 B;  2WFN A;  5A37 A;  2WA7 A;  3CO1 A;  1BKR A;  2HKP A;  3REP B;  1PA7 A;  2WA6 A;  1SH6 A;  2E9K A;  3F7P A;  2EYI A;  4B7L A;  3I6X A;  3KMU B;  3JAK M;  1WJO A;  1H67 A;  2K2R A;  2IGP A;  2YRN A;  2DK9 A;  4TXI A;  2D87 A;  2EQO A;  4Q59 A;  2D85 A;  1TJT A;  3KY9 A;  2HL8 A;  3HOP A;  2VE7 A;  5A36 A;  3FER A;  1UJO A;  4LVR A;  2VZD A;  1WYO A;  4EDL A;  2R8U A;  1PXY A;  1SH5 A;  3JAR M;  2HL9 A;  2L3G A;  4EDN A;  5FMT A;  3KMW B;  1DXX A;  2QJZ A;  3HOC A;  2EYN A;  1WYN A;  1RT8 A;  1VKA A;  2VZC A;  1WYQ A;  1UEG A;  1P2X A;  3JAL M;  2WE6 A;  2VE7 C;  5J8E A; 
#chains in the Genus database with same CATH homology
 1P5S A;  5L0O A;  1WKU A;  5A38 A;  2VZI B;  5A4B A;  2K3S A;  1AOA A;  4TXK A;  2JV9 A;  2WA5 A;  1AA2 A;  2D86 A;  5BVR A;  1WYR A;  3HOR A;  4EDM A;  2RR8 A;  1MB8 A;  1WYM A;  4Q58 A;  2EE7 A;  1BHD A;  1WYL A;  1WIX A;  2D88 A;  2QJX A;  2R0O A;  2D89 A;  1V5K A;  2VZG B;  1QAG A;  1WYP A;  4Q57 B;  2WFN A;  5A37 A;  2WA7 A;  3CO1 A;  1BKR A;  3REP B;  1PA7 A;  2WA6 A;  1SH6 A;  2E9K A;  3F7P A;  2EYI A;  4B7L A;  3I6X A;  3KMU B;  3JAK M;  1WJO A;  1H67 A;  2K2R A;  2YRN A;  2DK9 A;  4TXI A;  2D87 A;  4Q59 A;  2D85 A;  1TJT A;  3KY9 A;  3HOP A;  5A36 A;  3FER A;  1UJO A;  2VZD A;  1WYO A;  4EDL A;  2R8U A;  1PXY A;  1SH5 A;  3JAR M;  2L3G A;  4EDN A;  3KMW B;  1DXX A;  2QJZ A;  3HOC A;  2EYN A;  1WYN A;  1RT8 A;  1VKA A;  2VZC A;  1WYQ A;  1UEG A;  1P2X A;  3JAL M;  5J8E A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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