3KMU | Genus

Total Genus 35

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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus	35
sequence length	124
structure length	124
Chain Sequence	AFDTLFDHAPDKLNVVKKTLITFVNKHLNKLNLEVTELETQFADGVYLVLLMGLLEGYFVPLHSFFLTPDSFEQKVLNVSFAFELMQDGGLEKPKPRPEDIVNCDLKSTLRVLYNLFTKYRNVE

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

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After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Genus data interpretation

molecule tags	Cell adhesion
source organism	Homo sapiens
publication title	The pseudoactive site of ILK is essential for its binding to alpha-Parvin and localization to focal adhesions. pubmed doi rcsb
molecule keywords	Integrin-linked kinase
total genus	35
structure length	124
sequence length	124
ec nomenclature
pdb deposition date	2009-11-11

pfam database annotations

chain	Pfam Accession Code	Pfam Family Identifier	Pfam Description
B	PF00307	CH	Calponin homology (CH) domain

Image from the rcsb pdb (www.rcsb.org)

cath code	Class	Architecture	Topology	Homology	Domain
1.10.418.10	Mainly Alpha	Orthogonal Bundle	Actin-binding Protein, T-fimbrin; domain 1	Calponin-like domain	3kmuB00

4Q58A 3HOCA 2WA6A 5A36A 1P5SA 3I6XA 2VZGB 1SH5A 1BKRA 1WYRA 2D87A 1SH6A 4B7LA 2D88A 4EDMA 1UEGA 1BHDA 1TJTA 1UJOA 2D89A 3KMUB 2R8UA 2L3GA 5BVRA 4EDLA 1WKUA 1H67A 1WIXA 2YRNA 1WYLA 2VZCA 3F7PA 1AA2A 1QAGA 2VZDA 5A4BA 1MB8A 2VZIB 1WYPA 2R0OA 2K3SA 5J8EA 1WYNA 3KMWB 2EYIA 3KY9A 3REPB 1WYOA 4TXKA 3JARM 1PA7A 1RT8A 2EE7A 2WA5A 1AOAA 1WYQA 2QJXA 1WYMA 2E9KA 3HORA 3FERA 5L0OA 4EDNA 5A38A 2DK9A 1VKAA 4Q57B 3HOPA 2RR8A 4TXIA 1P2XA 5A37A 4Q59A 1PXYA 3JAKM 1WJOA 3CO1A 2D86A 2QJZA 2JV9A 2WFNA 2K2RA 2D85A 2EYNA 2WA7A 1DXXA 3JALM 1V5KA
chains in the Genus database with same CATH superfamily

2VE7A 4Q58A 4DDPA 3HOCA 2WA6A 5A36A 3EAYA 1P5SA 3I6XA 2VZGB 1SH5A 1BKRA 1WYRA 2D87A 1SH6A 4B7LA 2D88A 4EDMA 1UEGA 1BHDA 1TJTA 1UJOA 5FMUA 5FMTA 2D89A 3KMUB 2R8UA 2L3GA 5BVRA 4EDLA 1WKUA 1H67A 1WIXA 2YRNA 1WYLA 2VZCA 3F7PA 2HL8A 1AA2A 1QAGA 2VZDA 5A4BA 3VP7A 1MB8A 2HL9A 2VZIB 1WYPA 2R0OA 2K3SA 5J8EA 2IGPA 1WYNA 3KMWB 2EYIA 3KY9A 3REPB 1WYOA 4LVRA 4TXKA 3JARM 1PA7A 1RT8A 2EE7A 2WA5A 1AOAA 1WYQA 2QJXA 2HKPA 1WYMA 2E9KA 3HORA 2VE7C 3FERA 5L0OA 4LVPA 4EDNA 5A38A 2DK9A 1VKAA 4Q57B 3HOPA 2RR8A 4TXIA 1P2XA 2WDTA 5A37A 4Q59A 1PXYA 3JAKM 1EUVA 1WJOA 3CO1A 2D86A 2EQOA 2QJZA 2JV9A 2WFNA 2K2RA 2D85A 2EYNA 2WA7A 2WE6A 1DXXA 3JALM 1V5KA
chains in the Genus database with same CATH topology

#chains in the Genus database with same CATH superfamily
 4Q58 A;  3HOC A;  2WA6 A;  5A36 A;  1P5S A;  3I6X A;  2VZG B;  1SH5 A;  1BKR A;  1WYR A;  2D87 A;  1SH6 A;  4B7L A;  2D88 A;  4EDM A;  1UEG A;  1BHD A;  1TJT A;  1UJO A;  2D89 A;  3KMU B;  2R8U A;  2L3G A;  5BVR A;  4EDL A;  1WKU A;  1H67 A;  1WIX A;  2YRN A;  1WYL A;  2VZC A;  3F7P A;  1AA2 A;  1QAG A;  2VZD A;  5A4B A;  1MB8 A;  2VZI B;  1WYP A;  2R0O A;  2K3S A;  5J8E A;  1WYN A;  3KMW B;  2EYI A;  3KY9 A;  3REP B;  1WYO A;  4TXK A;  3JAR M;  1PA7 A;  1RT8 A;  2EE7 A;  2WA5 A;  1AOA A;  1WYQ A;  2QJX A;  1WYM A;  2E9K A;  3HOR A;  3FER A;  5L0O A;  4EDN A;  5A38 A;  2DK9 A;  1VKA A;  4Q57 B;  3HOP A;  2RR8 A;  4TXI A;  1P2X A;  5A37 A;  4Q59 A;  1PXY A;  3JAK M;  1WJO A;  3CO1 A;  2D86 A;  2QJZ A;  2JV9 A;  2WFN A;  2K2R A;  2D85 A;  2EYN A;  2WA7 A;  1DXX A;  3JAL M;  1V5K A; 
#chains in the Genus database with same CATH topology
 2VE7 A;  4Q58 A;  4DDP A;  3HOC A;  2WA6 A;  5A36 A;  3EAY A;  1P5S A;  3I6X A;  2VZG B;  1SH5 A;  1BKR A;  1WYR A;  2D87 A;  1SH6 A;  4B7L A;  2D88 A;  4EDM A;  1UEG A;  1BHD A;  1TJT A;  1UJO A;  5FMU A;  5FMT A;  2D89 A;  3KMU B;  2R8U A;  2L3G A;  5BVR A;  4EDL A;  1WKU A;  1H67 A;  1WIX A;  2YRN A;  1WYL A;  2VZC A;  3F7P A;  2HL8 A;  1AA2 A;  1QAG A;  2VZD A;  5A4B A;  3VP7 A;  1MB8 A;  2HL9 A;  2VZI B;  1WYP A;  2R0O A;  2K3S A;  5J8E A;  2IGP A;  1WYN A;  3KMW B;  2EYI A;  3KY9 A;  3REP B;  1WYO A;  4LVR A;  4TXK A;  3JAR M;  1PA7 A;  1RT8 A;  2EE7 A;  2WA5 A;  1AOA A;  1WYQ A;  2QJX A;  2HKP A;  1WYM A;  2E9K A;  3HOR A;  2VE7 C;  3FER A;  5L0O A;  4LVP A;  4EDN A;  5A38 A;  2DK9 A;  1VKA A;  4Q57 B;  3HOP A;  2RR8 A;  4TXI A;  1P2X A;  2WDT A;  5A37 A;  4Q59 A;  1PXY A;  3JAK M;  1EUV A;  1WJO A;  3CO1 A;  2D86 A;  2EQO A;  2QJZ A;  2JV9 A;  2WFN A;  2K2R A;  2D85 A;  2EYN A;  2WA7 A;  2WE6 A;  1DXX A;  3JAL M;  1V5K A; 
#chains in the Genus database with same CATH homology
 4Q58 A;  3HOC A;  2WA6 A;  5A36 A;  1P5S A;  3I6X A;  2VZG B;  1SH5 A;  1BKR A;  1WYR A;  2D87 A;  1SH6 A;  4B7L A;  2D88 A;  4EDM A;  1UEG A;  1BHD A;  1TJT A;  1UJO A;  2D89 A;  3KMU B;  2R8U A;  2L3G A;  5BVR A;  4EDL A;  1WKU A;  1H67 A;  1WIX A;  2YRN A;  1WYL A;  2VZC A;  3F7P A;  1AA2 A;  1QAG A;  2VZD A;  5A4B A;  1MB8 A;  2VZI B;  1WYP A;  2R0O A;  2K3S A;  5J8E A;  1WYN A;  3KMW B;  2EYI A;  3KY9 A;  3REP B;  1WYO A;  4TXK A;  3JAR M;  1PA7 A;  1RT8 A;  2EE7 A;  2WA5 A;  1AOA A;  1WYQ A;  2QJX A;  1WYM A;  2E9K A;  3HOR A;  3FER A;  5L0O A;  4EDN A;  5A38 A;  2DK9 A;  1VKA A;  4Q57 B;  3HOP A;  2RR8 A;  4TXI A;  1P2X A;  5A37 A;  4Q59 A;  1PXY A;  3JAK M;  1WJO A;  3CO1 A;  2D86 A;  2QJZ A;  2JV9 A;  2WFN A;  2K2R A;  2D85 A;  2EYN A;  2WA7 A;  1DXX A;  3JAL M;  1V5K A;

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similar chains in the Genus database (?% sequence similarity)

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similar chains in the pdb database (?% sequence similarity)

#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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3KMUB

Total Genus

sequence length

structure length

Chain Sequence

Structure visualization

pfam database annotations