3KMWB

Crystal structure of the ilk/alpha-parvin core complex (mgatp)
Total Genus 40
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
40
sequence length
124
structure length
124
Chain Sequence
AFDTLFDHAPDKLNVVKKTLITFVNKHLNKLNLEVTELETQFADGVYLVLLMGLLEGYFVPLHSFFLTPDSFEQKVLNVSFAFELMQDGGLEKPKPRPEDIVNCDLKSTLRVLYNLFTKYRNVE
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title The pseudoactive site of ILK is essential for its binding to alpha-Parvin and localization to focal adhesions.
pubmed doi rcsb
molecule tags Cell adhesion
source organism Homo sapiens
molecule keywords Integrin-linked kinase
total genus 40
structure length 124
sequence length 124
ec nomenclature
pdb deposition date 2009-11-11

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
B PF00307 CH Calponin homology (CH) domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.418.10 Mainly Alpha Orthogonal Bundle Actin-binding Protein, T-fimbrin; domain 1 Calponin-like domain 3kmwB00
2VZDA 1QAGA 1WYMA 4EDLA 2QJZA 2D88A 2EE7A 1H67A 5A36A 1AOAA 2R8UA 1WYPA 2K2RA 1WYLA 1WYQA 1UJOA 2WFNA 1WIXA 2D86A 2D87A 2VZIB 4Q59A 5A37A 2WA7A 1RT8A 2D85A 3JALM 2E9KA 5BVRA 3HOPA 4B7LA 1V5KA 3FERA 3REPB 1PXYA 1AA2A 5L0OA 1DXXA 2WA5A 2YRNA 2L3GA 4TXIA 1VKAA 1TJTA 1SH6A 2EYIA 4EDNA 3KMWB 4TXKA 2WA6A 3I6XA 2QJXA 4Q58A 1MB8A 2VZCA 5A4BA 3JARM 3JAKM 1WYRA 2JV9A 1SH5A 1BKRA 2R0OA 1BHDA 4EDMA 2VZGB 3F7PA 1WJOA 5J8EA 3KY9A 4Q57B 3CO1A 3HORA 2K3SA 1WKUA 2DK9A 1PA7A 1UEGA 2EYNA 1WYOA 1P2XA 2RR8A 1WYNA 1P5SA 5A38A 2D89A 3KMUB 3HOCA
chains in the Genus database with same CATH superfamily
2VE7C 2VZDA 1QAGA 1WYMA 4EDLA 2QJZA 2EQOA 2D88A 2EE7A 1H67A 5A36A 2HKPA 1AOAA 1WYPA 2K2RA 1WYLA 1WYQA 1UJOA 2WFNA 1WIXA 4LVPA 2D86A 2D87A 2VZIB 4Q59A 5A37A 2WA7A 1RT8A 4LVRA 2D85A 3JALM 2E9KA 5BVRA 3HOPA 4B7LA 1V5KA 3FERA 3REPB 2HL8A 1PXYA 1AA2A 4DDPA 3VP7A 5L0OA 1DXXA 2WA5A 2YRNA 2L3GA 4TXIA 1VKAA 1TJTA 1SH6A 2EYIA 4EDNA 3KMWB 2IGPA 4TXKA 2VE7A 2WA6A 3I6XA 2QJXA 4Q58A 1MB8A 2VZCA 2WE6A 5A4BA 3EAYA 3JARM 3JAKM 1WYRA 2JV9A 1SH5A 1BKRA 2R0OA 1BHDA 4EDMA 2VZGB 3F7PA 1WJOA 5J8EA 3KY9A 4Q57B 3KMUB 5FMUA 1EUVA 3CO1A 3HORA 2K3SA 1WKUA 2DK9A 2HL9A 1PA7A 1UEGA 2EYNA 1WYOA 1P2XA 2RR8A 1WYNA 1P5SA 2WDTA 5FMTA 5A38A 2D89A 2R8UA 3HOCA
chains in the Genus database with same CATH topology
2VZDA 1QAGA 1WYMA 4EDLA 2QJZA 2D88A 2EE7A 1H67A 5A36A 1AOAA 2R8UA 1WYPA 2K2RA 1WYLA 1WYQA 1UJOA 2WFNA 1WIXA 2D86A 2D87A 2VZIB 4Q59A 5A37A 2WA7A 1RT8A 2D85A 3JALM 2E9KA 5BVRA 3HOPA 4B7LA 1V5KA 3FERA 3REPB 1PXYA 1AA2A 5L0OA 1DXXA 2WA5A 2YRNA 2L3GA 4TXIA 1VKAA 1TJTA 1SH6A 2EYIA 4EDNA 3KMWB 4TXKA 2WA6A 3I6XA 2QJXA 4Q58A 1MB8A 2VZCA 5A4BA 3JARM 3JAKM 1WYRA 2JV9A 1SH5A 1BKRA 2R0OA 1BHDA 4EDMA 2VZGB 3F7PA 1WJOA 5J8EA 3KY9A 4Q57B 3CO1A 3HORA 2K3SA 1WKUA 2DK9A 1PA7A 1UEGA 2EYNA 1WYOA 1P2XA 2RR8A 1WYNA 1P5SA 5A38A 2D89A 3KMUB 3HOCA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2VZD A;  1QAG A;  1WYM A;  4EDL A;  2QJZ A;  2D88 A;  2EE7 A;  1H67 A;  5A36 A;  1AOA A;  2R8U A;  1WYP A;  2K2R A;  1WYL A;  1WYQ A;  1UJO A;  2WFN A;  1WIX A;  2D86 A;  2D87 A;  2VZI B;  4Q59 A;  5A37 A;  2WA7 A;  1RT8 A;  2D85 A;  3JAL M;  2E9K A;  5BVR A;  3HOP A;  4B7L A;  1V5K A;  3FER A;  3REP B;  1PXY A;  1AA2 A;  5L0O A;  1DXX A;  2WA5 A;  2YRN A;  2L3G A;  4TXI A;  1VKA A;  1TJT A;  1SH6 A;  2EYI A;  4EDN A;  3KMW B;  4TXK A;  2WA6 A;  3I6X A;  2QJX A;  4Q58 A;  1MB8 A;  2VZC A;  5A4B A;  3JAR M;  3JAK M;  1WYR A;  2JV9 A;  1SH5 A;  1BKR A;  2R0O A;  1BHD A;  4EDM A;  2VZG B;  3F7P A;  1WJO A;  5J8E A;  3KY9 A;  4Q57 B;  3CO1 A;  3HOR A;  2K3S A;  1WKU A;  2DK9 A;  1PA7 A;  1UEG A;  2EYN A;  1WYO A;  1P2X A;  2RR8 A;  1WYN A;  1P5S A;  5A38 A;  2D89 A;  3KMU B;  3HOC A; 
#chains in the Genus database with same CATH topology
 2VE7 C;  2VZD A;  1QAG A;  1WYM A;  4EDL A;  2QJZ A;  2EQO A;  2D88 A;  2EE7 A;  1H67 A;  5A36 A;  2HKP A;  1AOA A;  1WYP A;  2K2R A;  1WYL A;  1WYQ A;  1UJO A;  2WFN A;  1WIX A;  4LVP A;  2D86 A;  2D87 A;  2VZI B;  4Q59 A;  5A37 A;  2WA7 A;  1RT8 A;  4LVR A;  2D85 A;  3JAL M;  2E9K A;  5BVR A;  3HOP A;  4B7L A;  1V5K A;  3FER A;  3REP B;  2HL8 A;  1PXY A;  1AA2 A;  4DDP A;  3VP7 A;  5L0O A;  1DXX A;  2WA5 A;  2YRN A;  2L3G A;  4TXI A;  1VKA A;  1TJT A;  1SH6 A;  2EYI A;  4EDN A;  3KMW B;  2IGP A;  4TXK A;  2VE7 A;  2WA6 A;  3I6X A;  2QJX A;  4Q58 A;  1MB8 A;  2VZC A;  2WE6 A;  5A4B A;  3EAY A;  3JAR M;  3JAK M;  1WYR A;  2JV9 A;  1SH5 A;  1BKR A;  2R0O A;  1BHD A;  4EDM A;  2VZG B;  3F7P A;  1WJO A;  5J8E A;  3KY9 A;  4Q57 B;  3KMU B;  5FMU A;  1EUV A;  3CO1 A;  3HOR A;  2K3S A;  1WKU A;  2DK9 A;  2HL9 A;  1PA7 A;  1UEG A;  2EYN A;  1WYO A;  1P2X A;  2RR8 A;  1WYN A;  1P5S A;  2WDT A;  5FMT A;  5A38 A;  2D89 A;  2R8U A;  3HOC A; 
#chains in the Genus database with same CATH homology
 2VZD A;  1QAG A;  1WYM A;  4EDL A;  2QJZ A;  2D88 A;  2EE7 A;  1H67 A;  5A36 A;  1AOA A;  2R8U A;  1WYP A;  2K2R A;  1WYL A;  1WYQ A;  1UJO A;  2WFN A;  1WIX A;  2D86 A;  2D87 A;  2VZI B;  4Q59 A;  5A37 A;  2WA7 A;  1RT8 A;  2D85 A;  3JAL M;  2E9K A;  5BVR A;  3HOP A;  4B7L A;  1V5K A;  3FER A;  3REP B;  1PXY A;  1AA2 A;  5L0O A;  1DXX A;  2WA5 A;  2YRN A;  2L3G A;  4TXI A;  1VKA A;  1TJT A;  1SH6 A;  2EYI A;  4EDN A;  3KMW B;  4TXK A;  2WA6 A;  3I6X A;  2QJX A;  4Q58 A;  1MB8 A;  2VZC A;  5A4B A;  3JAR M;  3JAK M;  1WYR A;  2JV9 A;  1SH5 A;  1BKR A;  2R0O A;  1BHD A;  4EDM A;  2VZG B;  3F7P A;  1WJO A;  5J8E A;  3KY9 A;  4Q57 B;  3CO1 A;  3HOR A;  2K3S A;  1WKU A;  2DK9 A;  1PA7 A;  1UEG A;  2EYN A;  1WYO A;  1P2X A;  2RR8 A;  1WYN A;  1P5S A;  5A38 A;  2D89 A;  3KMU B;  3HOC A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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