4EDLA

Crystal structure of beta-parvin ch2 domain
Total Genus 43
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
43
sequence length
129
structure length
129
Chain Sequence
RFERDAFDTLFDHAPDKLSVVKKSLITFVNKHLNKLNLEVTELETQFADGVYLVLLMGLLEDYFVPLHHFYLTPESFDQKVHNVSFAFELMLDGGLKKPKARPEDVVNLDLKSTLRVLYNLFTKYKNVE
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Structural basis for paxillin binding and focal adhesion targeting of beta-parvin.
pubmed doi rcsb
molecule tags Signaling protein
source organism Homo sapiens
molecule keywords Beta-parvin
total genus 43
structure length 129
sequence length 129
chains with identical sequence B, C, D, E, F
ec nomenclature
pdb deposition date 2012-03-27

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00307 CH Calponin homology (CH) domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.418.10 Mainly Alpha Orthogonal Bundle Actin-binding Protein, T-fimbrin; domain 1 Calponin-like domain 4edlA00
1RT8A 4B7LA 2RR8A 3KMWB 5L0OA 1P5SA 1WYPA 1PXYA 2WA7A 2DK9A 1AOAA 1SH6A 2K3SA 1BHDA 2K2RA 1V5KA 2VZGB 4EDLA 1BKRA 1UEGA 5A36A 3I6XA 4TXIA 1WYLA 3HOCA 3JALM 2QJZA 2VZCA 3F7PA 1WJOA 1WYQA 3REPB 4TXKA 2VZDA 2YRNA 1MB8A 2D85A 5A4BA 1WYNA 2EYIA 2JV9A 1DXXA 2D87A 3FERA 3HOPA 2QJXA 2WFNA 5A38A 1VKAA 2E9KA 3KY9A 2R0OA 2EYNA 4Q59A 5J8EA 1AA2A 1WKUA 2EE7A 2R8UA 5BVRA 1QAGA 1WYOA 3KMUB 1WYMA 1PA7A 3JAKM 2WA6A 1WIXA 3JARM 1H67A 2D89A 1WYRA 4EDMA 1TJTA 2D88A 1P2XA 3CO1A 1SH5A 3HORA 5A37A 2D86A 1UJOA 4Q58A 4Q57B 2L3GA 2WA5A 2VZIB 4EDNA
chains in the Genus database with same CATH superfamily
1RT8A 4B7LA 2RR8A 3KMWB 5L0OA 1P5SA 1WYPA 2EQOA 1PXYA 2WA7A 2IGPA 2DK9A 1EUVA 1AOAA 1SH6A 2K3SA 1BHDA 2K2RA 1V5KA 2VZGB 4EDLA 1BKRA 3EAYA 1UEGA 5A36A 3I6XA 4TXIA 1WYLA 3HOCA 3JALM 2QJZA 4LVRA 2HL9A 2VZCA 2VE7A 3F7PA 1WJOA 4LVPA 1WYQA 3REPB 4TXKA 2VZDA 2YRNA 1MB8A 2D85A 5A4BA 1WYNA 2EYIA 2JV9A 1DXXA 2D87A 2VE7C 3FERA 2WDTA 3HOPA 2QJXA 2WFNA 5A38A 1VKAA 2E9KA 3KY9A 2R0OA 2EYNA 4Q59A 5J8EA 5FMUA 1AA2A 1WKUA 2EE7A 2R8UA 5BVRA 1QAGA 1WYOA 3KMUB 1WYMA 1PA7A 3JAKM 2WA6A 1WIXA 2HL8A 3JARM 1H67A 2D89A 1WYRA 4EDMA 1TJTA 3VP7A 2D88A 1P2XA 2HKPA 3CO1A 1SH5A 5FMTA 4DDPA 3HORA 5A37A 2D86A 1UJOA 4Q58A 4Q57B 2L3GA 2WA5A 2WE6A 2VZIB 4EDNA
chains in the Genus database with same CATH topology
1RT8A 4B7LA 2RR8A 3KMWB 5L0OA 1P5SA 1WYPA 1PXYA 2WA7A 2DK9A 1AOAA 1SH6A 2K3SA 1BHDA 2K2RA 1V5KA 2VZGB 4EDLA 1BKRA 1UEGA 5A36A 3I6XA 4TXIA 1WYLA 3HOCA 3JALM 2QJZA 2VZCA 3F7PA 1WJOA 1WYQA 3REPB 4TXKA 2VZDA 2YRNA 1MB8A 2D85A 5A4BA 1WYNA 2EYIA 2JV9A 1DXXA 2D87A 3FERA 3HOPA 2QJXA 2WFNA 5A38A 1VKAA 2E9KA 3KY9A 2R0OA 2EYNA 4Q59A 5J8EA 1AA2A 1WKUA 2EE7A 2R8UA 5BVRA 1QAGA 1WYOA 3KMUB 1WYMA 1PA7A 3JAKM 2WA6A 1WIXA 3JARM 1H67A 2D89A 1WYRA 4EDMA 1TJTA 2D88A 1P2XA 3CO1A 1SH5A 3HORA 5A37A 2D86A 1UJOA 4Q58A 4Q57B 2L3GA 2WA5A 2VZIB 4EDNA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1RT8 A;  4B7L A;  2RR8 A;  3KMW B;  5L0O A;  1P5S A;  1WYP A;  1PXY A;  2WA7 A;  2DK9 A;  1AOA A;  1SH6 A;  2K3S A;  1BHD A;  2K2R A;  1V5K A;  2VZG B;  4EDL A;  1BKR A;  1UEG A;  5A36 A;  3I6X A;  4TXI A;  1WYL A;  3HOC A;  3JAL M;  2QJZ A;  2VZC A;  3F7P A;  1WJO A;  1WYQ A;  3REP B;  4TXK A;  2VZD A;  2YRN A;  1MB8 A;  2D85 A;  5A4B A;  1WYN A;  2EYI A;  2JV9 A;  1DXX A;  2D87 A;  3FER A;  3HOP A;  2QJX A;  2WFN A;  5A38 A;  1VKA A;  2E9K A;  3KY9 A;  2R0O A;  2EYN A;  4Q59 A;  5J8E A;  1AA2 A;  1WKU A;  2EE7 A;  2R8U A;  5BVR A;  1QAG A;  1WYO A;  3KMU B;  1WYM A;  1PA7 A;  3JAK M;  2WA6 A;  1WIX A;  3JAR M;  1H67 A;  2D89 A;  1WYR A;  4EDM A;  1TJT A;  2D88 A;  1P2X A;  3CO1 A;  1SH5 A;  3HOR A;  5A37 A;  2D86 A;  1UJO A;  4Q58 A;  4Q57 B;  2L3G A;  2WA5 A;  2VZI B;  4EDN A; 
#chains in the Genus database with same CATH topology
 1RT8 A;  4B7L A;  2RR8 A;  3KMW B;  5L0O A;  1P5S A;  1WYP A;  2EQO A;  1PXY A;  2WA7 A;  2IGP A;  2DK9 A;  1EUV A;  1AOA A;  1SH6 A;  2K3S A;  1BHD A;  2K2R A;  1V5K A;  2VZG B;  4EDL A;  1BKR A;  3EAY A;  1UEG A;  5A36 A;  3I6X A;  4TXI A;  1WYL A;  3HOC A;  3JAL M;  2QJZ A;  4LVR A;  2HL9 A;  2VZC A;  2VE7 A;  3F7P A;  1WJO A;  4LVP A;  1WYQ A;  3REP B;  4TXK A;  2VZD A;  2YRN A;  1MB8 A;  2D85 A;  5A4B A;  1WYN A;  2EYI A;  2JV9 A;  1DXX A;  2D87 A;  2VE7 C;  3FER A;  2WDT A;  3HOP A;  2QJX A;  2WFN A;  5A38 A;  1VKA A;  2E9K A;  3KY9 A;  2R0O A;  2EYN A;  4Q59 A;  5J8E A;  5FMU A;  1AA2 A;  1WKU A;  2EE7 A;  2R8U A;  5BVR A;  1QAG A;  1WYO A;  3KMU B;  1WYM A;  1PA7 A;  3JAK M;  2WA6 A;  1WIX A;  2HL8 A;  3JAR M;  1H67 A;  2D89 A;  1WYR A;  4EDM A;  1TJT A;  3VP7 A;  2D88 A;  1P2X A;  2HKP A;  3CO1 A;  1SH5 A;  5FMT A;  4DDP A;  3HOR A;  5A37 A;  2D86 A;  1UJO A;  4Q58 A;  4Q57 B;  2L3G A;  2WA5 A;  2WE6 A;  2VZI B;  4EDN A; 
#chains in the Genus database with same CATH homology
 1RT8 A;  4B7L A;  2RR8 A;  3KMW B;  5L0O A;  1P5S A;  1WYP A;  1PXY A;  2WA7 A;  2DK9 A;  1AOA A;  1SH6 A;  2K3S A;  1BHD A;  2K2R A;  1V5K A;  2VZG B;  4EDL A;  1BKR A;  1UEG A;  5A36 A;  3I6X A;  4TXI A;  1WYL A;  3HOC A;  3JAL M;  2QJZ A;  2VZC A;  3F7P A;  1WJO A;  1WYQ A;  3REP B;  4TXK A;  2VZD A;  2YRN A;  1MB8 A;  2D85 A;  5A4B A;  1WYN A;  2EYI A;  2JV9 A;  1DXX A;  2D87 A;  3FER A;  3HOP A;  2QJX A;  2WFN A;  5A38 A;  1VKA A;  2E9K A;  3KY9 A;  2R0O A;  2EYN A;  4Q59 A;  5J8E A;  1AA2 A;  1WKU A;  2EE7 A;  2R8U A;  5BVR A;  1QAG A;  1WYO A;  3KMU B;  1WYM A;  1PA7 A;  3JAK M;  2WA6 A;  1WIX A;  3JAR M;  1H67 A;  2D89 A;  1WYR A;  4EDM A;  1TJT A;  2D88 A;  1P2X A;  3CO1 A;  1SH5 A;  3HOR A;  5A37 A;  2D86 A;  1UJO A;  4Q58 A;  4Q57 B;  2L3G A;  2WA5 A;  2VZI B;  4EDN A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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#similar chains, but unknotted
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