4EDM | Genus

Total Genus 38

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus	38
sequence length	127
structure length	127
Chain Sequence	ERDAFDTLFDHAPDKLSVVKKSLITFVNKHLNKLNLEVTELETQFADGVYLVLLMGLLEDYFVPLHHFYLTPESFDQKVHNVSFAFELMLDGGLKKPKARPEDVVNLDLKSTLRVLYNLFTKYKNVE

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

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After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Genus data interpretation

molecule tags	Signaling protein
source organism	Homo sapiens
publication title	Structural basis for paxillin binding and focal adhesion targeting of beta-parvin. pubmed doi rcsb
molecule keywords	Beta-parvin
total genus	38
structure length	127
sequence length	127
chains with identical sequence	B
ec nomenclature
pdb deposition date	2012-03-27

pfam database annotations

chain	Pfam Accession Code	Pfam Family Identifier	Pfam Description
A	PF00307	CH	Calponin homology (CH) domain

Image from the rcsb pdb (www.rcsb.org)

cath code	Class	Architecture	Topology	Homology	Domain
1.10.418.10	Mainly Alpha	Orthogonal Bundle	Actin-binding Protein, T-fimbrin; domain 1	Calponin-like domain	4edmA00

2EE7A 2EYIA 4TXIA 1WYNA 2D85A 4Q57B 2DK9A 3KMWB 4B7LA 1DXXA 2JV9A 1WYOA 2L3GA 3F7PA 2E9KA 5BVRA 1SH6A 1P2XA 2WA6A 4EDNA 3KY9A 3KMUB 2R0OA 1BKRA 2YRNA 1VKAA 2VZIB 5A36A 1WYPA 4Q59A 1AA2A 1WYQA 1WYRA 2D89A 1P5SA 4Q58A 1WJOA 2RR8A 3JARM 3I6XA 2VZGB 5J8EA 2QJZA 2D88A 2R8UA 3HOCA 3HOPA 2K2RA 3JAKM 3REPB 2WFNA 2WA5A 1WYLA 2WA7A 3CO1A 1UEGA 1TJTA 2K3SA 2D87A 1SH5A 1RT8A 1AOAA 1WYMA 5A38A 5L0OA 1H67A 3HORA 1WIXA 1MB8A 4EDMA 2VZCA 1QAGA 5A4BA 4TXKA 1UJOA 1PA7A 4EDLA 3JALM 1V5KA 2D86A 3FERA 1WKUA 1BHDA 1PXYA 2EYNA 2QJXA 5A37A 2VZDA
chains in the Genus database with same CATH superfamily

2HL8A 2EE7A 2EYIA 4TXIA 1WYNA 2D85A 4Q57B 2DK9A 3KMWB 4B7LA 1DXXA 2JV9A 1WYOA 2L3GA 3F7PA 2E9KA 2WDTA 5BVRA 1SH6A 5FMUA 1P2XA 2WA6A 4EDNA 3KY9A 2VE7A 3KMUB 2R0OA 1BKRA 2YRNA 2HKPA 1VKAA 2VZIB 5A36A 1WYPA 4Q59A 1AA2A 1WYQA 1WYRA 2D89A 1EUVA 3EAYA 1P5SA 4Q58A 1WJOA 2RR8A 2EQOA 3VP7A 2WE6A 3JARM 3I6XA 2VZGB 5J8EA 5FMTA 2QJZA 2D88A 2R8UA 3HOCA 3HOPA 2K2RA 3JAKM 2IGPA 2HL9A 3REPB 2WFNA 2WA5A 1WYLA 2WA7A 3CO1A 1UEGA 1TJTA 2K3SA 2D87A 1SH5A 1RT8A 1AOAA 1WYMA 5A38A 5L0OA 1H67A 3HORA 1WIXA 1MB8A 4EDMA 2VZCA 1QAGA 5A4BA 4TXKA 1UJOA 4LVPA 1PA7A 4EDLA 3JALM 1V5KA 2D86A 3FERA 1WKUA 1BHDA 1PXYA 2VE7C 4DDPA 2EYNA 2QJXA 5A37A 4LVRA 2VZDA
chains in the Genus database with same CATH topology

#chains in the Genus database with same CATH superfamily
 2EE7 A;  2EYI A;  4TXI A;  1WYN A;  2D85 A;  4Q57 B;  2DK9 A;  3KMW B;  4B7L A;  1DXX A;  2JV9 A;  1WYO A;  2L3G A;  3F7P A;  2E9K A;  5BVR A;  1SH6 A;  1P2X A;  2WA6 A;  4EDN A;  3KY9 A;  3KMU B;  2R0O A;  1BKR A;  2YRN A;  1VKA A;  2VZI B;  5A36 A;  1WYP A;  4Q59 A;  1AA2 A;  1WYQ A;  1WYR A;  2D89 A;  1P5S A;  4Q58 A;  1WJO A;  2RR8 A;  3JAR M;  3I6X A;  2VZG B;  5J8E A;  2QJZ A;  2D88 A;  2R8U A;  3HOC A;  3HOP A;  2K2R A;  3JAK M;  3REP B;  2WFN A;  2WA5 A;  1WYL A;  2WA7 A;  3CO1 A;  1UEG A;  1TJT A;  2K3S A;  2D87 A;  1SH5 A;  1RT8 A;  1AOA A;  1WYM A;  5A38 A;  5L0O A;  1H67 A;  3HOR A;  1WIX A;  1MB8 A;  4EDM A;  2VZC A;  1QAG A;  5A4B A;  4TXK A;  1UJO A;  1PA7 A;  4EDL A;  3JAL M;  1V5K A;  2D86 A;  3FER A;  1WKU A;  1BHD A;  1PXY A;  2EYN A;  2QJX A;  5A37 A;  2VZD A; 
#chains in the Genus database with same CATH topology
 2HL8 A;  2EE7 A;  2EYI A;  4TXI A;  1WYN A;  2D85 A;  4Q57 B;  2DK9 A;  3KMW B;  4B7L A;  1DXX A;  2JV9 A;  1WYO A;  2L3G A;  3F7P A;  2E9K A;  2WDT A;  5BVR A;  1SH6 A;  5FMU A;  1P2X A;  2WA6 A;  4EDN A;  3KY9 A;  2VE7 A;  3KMU B;  2R0O A;  1BKR A;  2YRN A;  2HKP A;  1VKA A;  2VZI B;  5A36 A;  1WYP A;  4Q59 A;  1AA2 A;  1WYQ A;  1WYR A;  2D89 A;  1EUV A;  3EAY A;  1P5S A;  4Q58 A;  1WJO A;  2RR8 A;  2EQO A;  3VP7 A;  2WE6 A;  3JAR M;  3I6X A;  2VZG B;  5J8E A;  5FMT A;  2QJZ A;  2D88 A;  2R8U A;  3HOC A;  3HOP A;  2K2R A;  3JAK M;  2IGP A;  2HL9 A;  3REP B;  2WFN A;  2WA5 A;  1WYL A;  2WA7 A;  3CO1 A;  1UEG A;  1TJT A;  2K3S A;  2D87 A;  1SH5 A;  1RT8 A;  1AOA A;  1WYM A;  5A38 A;  5L0O A;  1H67 A;  3HOR A;  1WIX A;  1MB8 A;  4EDM A;  2VZC A;  1QAG A;  5A4B A;  4TXK A;  1UJO A;  4LVP A;  1PA7 A;  4EDL A;  3JAL M;  1V5K A;  2D86 A;  3FER A;  1WKU A;  1BHD A;  1PXY A;  2VE7 C;  4DDP A;  2EYN A;  2QJX A;  5A37 A;  4LVR A;  2VZD A; 
#chains in the Genus database with same CATH homology
 2EE7 A;  2EYI A;  4TXI A;  1WYN A;  2D85 A;  4Q57 B;  2DK9 A;  3KMW B;  4B7L A;  1DXX A;  2JV9 A;  1WYO A;  2L3G A;  3F7P A;  2E9K A;  5BVR A;  1SH6 A;  1P2X A;  2WA6 A;  4EDN A;  3KY9 A;  3KMU B;  2R0O A;  1BKR A;  2YRN A;  1VKA A;  2VZI B;  5A36 A;  1WYP A;  4Q59 A;  1AA2 A;  1WYQ A;  1WYR A;  2D89 A;  1P5S A;  4Q58 A;  1WJO A;  2RR8 A;  3JAR M;  3I6X A;  2VZG B;  5J8E A;  2QJZ A;  2D88 A;  2R8U A;  3HOC A;  3HOP A;  2K2R A;  3JAK M;  3REP B;  2WFN A;  2WA5 A;  1WYL A;  2WA7 A;  3CO1 A;  1UEG A;  1TJT A;  2K3S A;  2D87 A;  1SH5 A;  1RT8 A;  1AOA A;  1WYM A;  5A38 A;  5L0O A;  1H67 A;  3HOR A;  1WIX A;  1MB8 A;  4EDM A;  2VZC A;  1QAG A;  5A4B A;  4TXK A;  1UJO A;  1PA7 A;  4EDL A;  3JAL M;  1V5K A;  2D86 A;  3FER A;  1WKU A;  1BHD A;  1PXY A;  2EYN A;  2QJX A;  5A37 A;  2VZD A;

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similar chains in the Genus database (?% sequence similarity)

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similar chains in the pdb database (?% sequence similarity)

#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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4EDMA

Total Genus

sequence length

structure length

Chain Sequence

Structure visualization

pfam database annotations