4EDNA

Crystal structure of beta-parvin ch2 domain in complex with paxillin ld1 motif
Total Genus 35
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
35
sequence length
127
structure length
127
Chain Sequence
ERDAFDTLFDHAPDKLSVVKKSLITFVNKHLNKLNLEVTELETQFADGVYLVLLMGLLEDYFVPLHHFYLTPESFDQKVHNVSFAFELMLDGGLKKPKARPEDVVNLDLKSTLRVLYNLFTKYKNVE
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Structural basis for paxillin binding and focal adhesion targeting of beta-parvin.
pubmed doi rcsb
molecule tags Signaling protein/cell adhesion
source organism Homo sapiens
molecule keywords Beta-parvin
total genus 35
structure length 127
sequence length 127
chains with identical sequence B, C, D, E, F, G, H, I, J
ec nomenclature
pdb deposition date 2012-03-27

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00307 CH Calponin homology (CH) domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.418.10 Mainly Alpha Orthogonal Bundle Actin-binding Protein, T-fimbrin; domain 1 Calponin-like domain 4ednA00
2QJZA 1BKRA 1AA2A 1WYOA 1PA7A 1MB8A 2D87A 3F7PA 2WA5A 2R8UA 1WIXA 2D88A 2L3GA 1WYLA 3KY9A 2D85A 1AOAA 2VZCA 2EYNA 3HOCA 1BHDA 3HOPA 1V5KA 2EE7A 4B7LA 1P5SA 1WYNA 2D89A 2JV9A 1WJOA 3KMWB 3FERA 2WA7A 1QAGA 5A38A 4Q57B 2WFNA 3CO1A 1UJOA 5A37A 1WYQA 2QJXA 1WYMA 1PXYA 3JALM 2VZIB 3HORA 1P2XA 1WYRA 2VZGB 1VKAA 4EDMA 1SH6A 3JAKM 1WYPA 2K2RA 2R0OA 2DK9A 2K3SA 4TXKA 1UEGA 5BVRA 2EYIA 5J8EA 1RT8A 3I6XA 4EDLA 5L0OA 4Q58A 4EDNA 2VZDA 2YRNA 3JARM 5A4BA 5A36A 3KMUB 3REPB 1SH5A 2RR8A 1TJTA 1H67A 4TXIA 1DXXA 2D86A 2E9KA 2WA6A 4Q59A 1WKUA
chains in the Genus database with same CATH superfamily
2WE6A 2QJZA 1BKRA 1AA2A 1WYOA 1PA7A 1MB8A 2D87A 3VP7A 3F7PA 2VE7A 2WA5A 1EUVA 1WIXA 2R8UA 2D88A 2HL8A 2L3GA 1WYLA 3KY9A 2HL9A 2D85A 1AOAA 4LVRA 2VZCA 2EYNA 3HOCA 1BHDA 3HOPA 1V5KA 2EE7A 2IGPA 3EAYA 4B7LA 1P5SA 1WYNA 2D89A 2JV9A 1WJOA 5FMTA 4LVPA 3KMWB 3FERA 2WA7A 1QAGA 5A38A 4Q57B 2WFNA 3CO1A 1UJOA 5FMUA 5A37A 1WYQA 2QJXA 1WYMA 1PXYA 3JALM 2VZIB 3HORA 1P2XA 1WYRA 2VZGB 1VKAA 4EDMA 1SH6A 3JAKM 2WDTA 1WYPA 2K2RA 2R0OA 2EQOA 2DK9A 4DDPA 2K3SA 4TXKA 1UEGA 5BVRA 2EYIA 5J8EA 1RT8A 3I6XA 4EDLA 2HKPA 5L0OA 4Q58A 4EDNA 2VZDA 2YRNA 3JARM 5A4BA 5A36A 2VE7C 3KMUB 1SH5A 3REPB 2RR8A 1TJTA 1H67A 4TXIA 1DXXA 2D86A 2E9KA 2WA6A 4Q59A 1WKUA
chains in the Genus database with same CATH topology
2QJZA 1BKRA 1AA2A 1WYOA 1PA7A 1MB8A 2D87A 3F7PA 2WA5A 2R8UA 1WIXA 2D88A 2L3GA 1WYLA 3KY9A 2D85A 1AOAA 2VZCA 2EYNA 3HOCA 1BHDA 3HOPA 1V5KA 2EE7A 4B7LA 1P5SA 1WYNA 2D89A 2JV9A 1WJOA 3KMWB 3FERA 2WA7A 1QAGA 5A38A 4Q57B 2WFNA 3CO1A 1UJOA 5A37A 1WYQA 2QJXA 1WYMA 1PXYA 3JALM 2VZIB 3HORA 1P2XA 1WYRA 2VZGB 1VKAA 4EDMA 1SH6A 3JAKM 1WYPA 2K2RA 2R0OA 2DK9A 2K3SA 4TXKA 1UEGA 5BVRA 2EYIA 5J8EA 1RT8A 3I6XA 4EDLA 5L0OA 4Q58A 4EDNA 2VZDA 2YRNA 3JARM 5A4BA 5A36A 3KMUB 3REPB 1SH5A 2RR8A 1TJTA 1H67A 4TXIA 1DXXA 2D86A 2E9KA 2WA6A 4Q59A 1WKUA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2QJZ A;  1BKR A;  1AA2 A;  1WYO A;  1PA7 A;  1MB8 A;  2D87 A;  3F7P A;  2WA5 A;  2R8U A;  1WIX A;  2D88 A;  2L3G A;  1WYL A;  3KY9 A;  2D85 A;  1AOA A;  2VZC A;  2EYN A;  3HOC A;  1BHD A;  3HOP A;  1V5K A;  2EE7 A;  4B7L A;  1P5S A;  1WYN A;  2D89 A;  2JV9 A;  1WJO A;  3KMW B;  3FER A;  2WA7 A;  1QAG A;  5A38 A;  4Q57 B;  2WFN A;  3CO1 A;  1UJO A;  5A37 A;  1WYQ A;  2QJX A;  1WYM A;  1PXY A;  3JAL M;  2VZI B;  3HOR A;  1P2X A;  1WYR A;  2VZG B;  1VKA A;  4EDM A;  1SH6 A;  3JAK M;  1WYP A;  2K2R A;  2R0O A;  2DK9 A;  2K3S A;  4TXK A;  1UEG A;  5BVR A;  2EYI A;  5J8E A;  1RT8 A;  3I6X A;  4EDL A;  5L0O A;  4Q58 A;  4EDN A;  2VZD A;  2YRN A;  3JAR M;  5A4B A;  5A36 A;  3KMU B;  3REP B;  1SH5 A;  2RR8 A;  1TJT A;  1H67 A;  4TXI A;  1DXX A;  2D86 A;  2E9K A;  2WA6 A;  4Q59 A;  1WKU A; 
#chains in the Genus database with same CATH topology
 2WE6 A;  2QJZ A;  1BKR A;  1AA2 A;  1WYO A;  1PA7 A;  1MB8 A;  2D87 A;  3VP7 A;  3F7P A;  2VE7 A;  2WA5 A;  1EUV A;  1WIX A;  2R8U A;  2D88 A;  2HL8 A;  2L3G A;  1WYL A;  3KY9 A;  2HL9 A;  2D85 A;  1AOA A;  4LVR A;  2VZC A;  2EYN A;  3HOC A;  1BHD A;  3HOP A;  1V5K A;  2EE7 A;  2IGP A;  3EAY A;  4B7L A;  1P5S A;  1WYN A;  2D89 A;  2JV9 A;  1WJO A;  5FMT A;  4LVP A;  3KMW B;  3FER A;  2WA7 A;  1QAG A;  5A38 A;  4Q57 B;  2WFN A;  3CO1 A;  1UJO A;  5FMU A;  5A37 A;  1WYQ A;  2QJX A;  1WYM A;  1PXY A;  3JAL M;  2VZI B;  3HOR A;  1P2X A;  1WYR A;  2VZG B;  1VKA A;  4EDM A;  1SH6 A;  3JAK M;  2WDT A;  1WYP A;  2K2R A;  2R0O A;  2EQO A;  2DK9 A;  4DDP A;  2K3S A;  4TXK A;  1UEG A;  5BVR A;  2EYI A;  5J8E A;  1RT8 A;  3I6X A;  4EDL A;  2HKP A;  5L0O A;  4Q58 A;  4EDN A;  2VZD A;  2YRN A;  3JAR M;  5A4B A;  5A36 A;  2VE7 C;  3KMU B;  1SH5 A;  3REP B;  2RR8 A;  1TJT A;  1H67 A;  4TXI A;  1DXX A;  2D86 A;  2E9K A;  2WA6 A;  4Q59 A;  1WKU A; 
#chains in the Genus database with same CATH homology
 2QJZ A;  1BKR A;  1AA2 A;  1WYO A;  1PA7 A;  1MB8 A;  2D87 A;  3F7P A;  2WA5 A;  2R8U A;  1WIX A;  2D88 A;  2L3G A;  1WYL A;  3KY9 A;  2D85 A;  1AOA A;  2VZC A;  2EYN A;  3HOC A;  1BHD A;  3HOP A;  1V5K A;  2EE7 A;  4B7L A;  1P5S A;  1WYN A;  2D89 A;  2JV9 A;  1WJO A;  3KMW B;  3FER A;  2WA7 A;  1QAG A;  5A38 A;  4Q57 B;  2WFN A;  3CO1 A;  1UJO A;  5A37 A;  1WYQ A;  2QJX A;  1WYM A;  1PXY A;  3JAL M;  2VZI B;  3HOR A;  1P2X A;  1WYR A;  2VZG B;  1VKA A;  4EDM A;  1SH6 A;  3JAK M;  1WYP A;  2K2R A;  2R0O A;  2DK9 A;  2K3S A;  4TXK A;  1UEG A;  5BVR A;  2EYI A;  5J8E A;  1RT8 A;  3I6X A;  4EDL A;  5L0O A;  4Q58 A;  4EDN A;  2VZD A;  2YRN A;  3JAR M;  5A4B A;  5A36 A;  3KMU B;  3REP B;  1SH5 A;  2RR8 A;  1TJT A;  1H67 A;  4TXI A;  1DXX A;  2D86 A;  2E9K A;  2WA6 A;  4Q59 A;  1WKU A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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