4EDNA

Crystal structure of beta-parvin ch2 domain in complex with paxillin ld1 motif
Total Genus 35
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
35
sequence length
127
structure length
127
Chain Sequence
ERDAFDTLFDHAPDKLSVVKKSLITFVNKHLNKLNLEVTELETQFADGVYLVLLMGLLEDYFVPLHHFYLTPESFDQKVHNVSFAFELMLDGGLKKPKARPEDVVNLDLKSTLRVLYNLFTKYKNVE
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Structural basis for paxillin binding and focal adhesion targeting of beta-parvin.
pubmed doi rcsb
molecule tags Signaling protein/cell adhesion
source organism Homo sapiens
molecule keywords Beta-parvin
total genus 35
structure length 127
sequence length 127
chains with identical sequence B, C, D, E, F, G, H, I, J
ec nomenclature
pdb deposition date 2012-03-27

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00307 CH Calponin homology (CH) domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.418.10 Mainly Alpha Orthogonal Bundle Actin-binding Protein, T-fimbrin; domain 1 Calponin-like domain 4ednA00
1BHDA 1H67A 1P2XA 2WA7A 1WYPA 1DXXA 4EDNA 1WYRA 1SH6A 4B7LA 1WIXA 2D89A 2VZGB 4Q57B 4EDLA 3JAKM 2R8UA 4TXIA 3KY9A 2D85A 2WA5A 2RR8A 2YRNA 3JALM 2WFNA 1P5SA 3FERA 4EDMA 1WYLA 1AOAA 5J8EA 1PXYA 3HORA 2D86A 5A36A 2EE7A 3JARM 1UEGA 5A38A 3CO1A 2K2RA 1WYQA 1V5KA 1VKAA 1SH5A 2EYNA 2VZIB 2QJXA 1AA2A 3KMWB 2JV9A 2VZDA 2R0OA 1WYMA 2D87A 2VZCA 1WKUA 4Q58A 1WYOA 2E9KA 1QAGA 1TJTA 2QJZA 5BVRA 1BKRA 3HOCA 1RT8A 2WA6A 5A4BA 5L0OA 3REPB 2EYIA 5A37A 1WJOA 3F7PA 2K3SA 2D88A 4Q59A 3I6XA 1PA7A 1WYNA 3HOPA 3KMUB 4TXKA 2DK9A 1UJOA 1MB8A 2L3GA
chains in the Genus database with same CATH superfamily
1BHDA 3EAYA 1H67A 1P2XA 2WA7A 1WYPA 1DXXA 4EDNA 1WYRA 2WE6A 1SH6A 3VP7A 4B7LA 1WIXA 2D89A 2HL9A 2VZGB 4Q57B 4EDLA 3JAKM 4LVPA 2R8UA 3KY9A 2WDTA 4TXIA 2D85A 2WA5A 2RR8A 2YRNA 3JALM 2HL8A 2WFNA 2EQOA 1P5SA 3FERA 4EDMA 1WYLA 1AOAA 2IGPA 5J8EA 1PXYA 3HORA 2D86A 5A36A 2EE7A 3JARM 1UEGA 5A38A 3CO1A 2K2RA 1WYQA 1V5KA 1VKAA 1SH5A 2EYNA 2VE7A 2VZIB 4DDPA 2QJXA 1AA2A 2HKPA 3KMWB 2JV9A 2VZDA 2R0OA 1WYMA 2D87A 2VZCA 1WKUA 4Q58A 5FMUA 1WYOA 2E9KA 1QAGA 1TJTA 5FMTA 2QJZA 5BVRA 1BKRA 3HOCA 1RT8A 4LVRA 2WA6A 2VE7C 5A4BA 1EUVA 5L0OA 3REPB 2EYIA 5A37A 1WJOA 3F7PA 2K3SA 2D88A 4Q59A 3I6XA 1PA7A 1WYNA 3HOPA 3KMUB 4TXKA 2DK9A 1UJOA 1MB8A 2L3GA
chains in the Genus database with same CATH topology
1BHDA 1H67A 1P2XA 2WA7A 1WYPA 1DXXA 4EDNA 1WYRA 1SH6A 4B7LA 1WIXA 2D89A 2VZGB 4Q57B 4EDLA 3JAKM 2R8UA 4TXIA 3KY9A 2D85A 2WA5A 2RR8A 2YRNA 3JALM 2WFNA 1P5SA 3FERA 4EDMA 1WYLA 1AOAA 5J8EA 1PXYA 3HORA 2D86A 5A36A 2EE7A 3JARM 1UEGA 5A38A 3CO1A 2K2RA 1WYQA 1V5KA 1VKAA 1SH5A 2EYNA 2VZIB 2QJXA 1AA2A 3KMWB 2JV9A 2VZDA 2R0OA 1WYMA 2D87A 2VZCA 1WKUA 4Q58A 1WYOA 2E9KA 1QAGA 1TJTA 2QJZA 5BVRA 1BKRA 3HOCA 1RT8A 2WA6A 5A4BA 5L0OA 3REPB 2EYIA 5A37A 1WJOA 3F7PA 2K3SA 2D88A 4Q59A 3I6XA 1PA7A 1WYNA 3HOPA 3KMUB 4TXKA 2DK9A 1UJOA 1MB8A 2L3GA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1BHD A;  1H67 A;  1P2X A;  2WA7 A;  1WYP A;  1DXX A;  4EDN A;  1WYR A;  1SH6 A;  4B7L A;  1WIX A;  2D89 A;  2VZG B;  4Q57 B;  4EDL A;  3JAK M;  2R8U A;  4TXI A;  3KY9 A;  2D85 A;  2WA5 A;  2RR8 A;  2YRN A;  3JAL M;  2WFN A;  1P5S A;  3FER A;  4EDM A;  1WYL A;  1AOA A;  5J8E A;  1PXY A;  3HOR A;  2D86 A;  5A36 A;  2EE7 A;  3JAR M;  1UEG A;  5A38 A;  3CO1 A;  2K2R A;  1WYQ A;  1V5K A;  1VKA A;  1SH5 A;  2EYN A;  2VZI B;  2QJX A;  1AA2 A;  3KMW B;  2JV9 A;  2VZD A;  2R0O A;  1WYM A;  2D87 A;  2VZC A;  1WKU A;  4Q58 A;  1WYO A;  2E9K A;  1QAG A;  1TJT A;  2QJZ A;  5BVR A;  1BKR A;  3HOC A;  1RT8 A;  2WA6 A;  5A4B A;  5L0O A;  3REP B;  2EYI A;  5A37 A;  1WJO A;  3F7P A;  2K3S A;  2D88 A;  4Q59 A;  3I6X A;  1PA7 A;  1WYN A;  3HOP A;  3KMU B;  4TXK A;  2DK9 A;  1UJO A;  1MB8 A;  2L3G A; 
#chains in the Genus database with same CATH topology
 1BHD A;  3EAY A;  1H67 A;  1P2X A;  2WA7 A;  1WYP A;  1DXX A;  4EDN A;  1WYR A;  2WE6 A;  1SH6 A;  3VP7 A;  4B7L A;  1WIX A;  2D89 A;  2HL9 A;  2VZG B;  4Q57 B;  4EDL A;  3JAK M;  4LVP A;  2R8U A;  3KY9 A;  2WDT A;  4TXI A;  2D85 A;  2WA5 A;  2RR8 A;  2YRN A;  3JAL M;  2HL8 A;  2WFN A;  2EQO A;  1P5S A;  3FER A;  4EDM A;  1WYL A;  1AOA A;  2IGP A;  5J8E A;  1PXY A;  3HOR A;  2D86 A;  5A36 A;  2EE7 A;  3JAR M;  1UEG A;  5A38 A;  3CO1 A;  2K2R A;  1WYQ A;  1V5K A;  1VKA A;  1SH5 A;  2EYN A;  2VE7 A;  2VZI B;  4DDP A;  2QJX A;  1AA2 A;  2HKP A;  3KMW B;  2JV9 A;  2VZD A;  2R0O A;  1WYM A;  2D87 A;  2VZC A;  1WKU A;  4Q58 A;  5FMU A;  1WYO A;  2E9K A;  1QAG A;  1TJT A;  5FMT A;  2QJZ A;  5BVR A;  1BKR A;  3HOC A;  1RT8 A;  4LVR A;  2WA6 A;  2VE7 C;  5A4B A;  1EUV A;  5L0O A;  3REP B;  2EYI A;  5A37 A;  1WJO A;  3F7P A;  2K3S A;  2D88 A;  4Q59 A;  3I6X A;  1PA7 A;  1WYN A;  3HOP A;  3KMU B;  4TXK A;  2DK9 A;  1UJO A;  1MB8 A;  2L3G A; 
#chains in the Genus database with same CATH homology
 1BHD A;  1H67 A;  1P2X A;  2WA7 A;  1WYP A;  1DXX A;  4EDN A;  1WYR A;  1SH6 A;  4B7L A;  1WIX A;  2D89 A;  2VZG B;  4Q57 B;  4EDL A;  3JAK M;  2R8U A;  4TXI A;  3KY9 A;  2D85 A;  2WA5 A;  2RR8 A;  2YRN A;  3JAL M;  2WFN A;  1P5S A;  3FER A;  4EDM A;  1WYL A;  1AOA A;  5J8E A;  1PXY A;  3HOR A;  2D86 A;  5A36 A;  2EE7 A;  3JAR M;  1UEG A;  5A38 A;  3CO1 A;  2K2R A;  1WYQ A;  1V5K A;  1VKA A;  1SH5 A;  2EYN A;  2VZI B;  2QJX A;  1AA2 A;  3KMW B;  2JV9 A;  2VZD A;  2R0O A;  1WYM A;  2D87 A;  2VZC A;  1WKU A;  4Q58 A;  1WYO A;  2E9K A;  1QAG A;  1TJT A;  2QJZ A;  5BVR A;  1BKR A;  3HOC A;  1RT8 A;  2WA6 A;  5A4B A;  5L0O A;  3REP B;  2EYI A;  5A37 A;  1WJO A;  3F7P A;  2K3S A;  2D88 A;  4Q59 A;  3I6X A;  1PA7 A;  1WYN A;  3HOP A;  3KMU B;  4TXK A;  2DK9 A;  1UJO A;  1MB8 A;  2L3G A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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