4GY2A

Crystal structure of apo-ia-actin complex
Total Genus 137
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
137
sequence length
411
structure length
411
Chain Sequence
IERPEDFLKDKENAIQWEKKEAERVEKNLDTLEKEALELYKKDSEQISNYSQTRQYFYDYQIESNPREKEYKNLRNAISKNKIDKPINVYYFESPEKFAFNKEIRTENQNEISLEKFNELKETIQDKLFKQDGFKDVSLYEPGNGDEKPTPLLIHLKLPKNTGMLPYINSNDVKTLIEQDYSIKIDKIVRIVIEGKQYIKAEASIVNSLDFKDDVSKGDLWGKENYSDWSNKLTPNELADVNDYMRGGYTAINNYLISNGPLNNPNPELDSKVNNIENALKLTPIPSNLIVYRRSGPQEFGLTLTSPEYDFNKIENIDAFKEKWEGKVITYPNFISTSIGSVNMSAFAKRKIILRINIPKDSPGAYLSAIPGYAGEYEVLLNHGSKFKINKVDSYKDGTVTKLILDATLIN
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Toxin/structural protein
source organism Clostridium perfringens
publication title Arginine ADP-ribosylation mechanism based on structural snapshots of iota-toxin and actin complex
pubmed doi rcsb
molecule keywords Iota toxin component Ia
total genus 137
structure length 411
sequence length 411
ec nomenclature ec 2.4.2.31: NAD(+)--protein-arginine ADP-ribosyltransferase.
pdb deposition date 2012-09-05

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF03496 ADPrib_exo_Tox ADP-ribosyltransferase exoenzyme
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.176.10 Alpha Beta Alpha-Beta Complex Toxin ADP-ribosyltransferase; Chain A, domain 1 Toxin ADP-ribosyltransferase; Chain A, domain 1 4gy2A02
3.90.176.10 Alpha Beta Alpha-Beta Complex Toxin ADP-ribosyltransferase; Chain A, domain 1 Toxin ADP-ribosyltransferase; Chain A, domain 1 4gy2A01
1YQYA 2A78B 5D1UA 4DV8A 4XSHB 5H03A 1QS2A 1OJQA 1ZXVA 1OJZA 4H0XA 2WN4A 1PWUA 1OG4A 4H0TA 2C8AA 2WN5A 2GWMA 1OG1A 1GZEA 2J3ZA 2C89A 4PKUA 2BOVB 1OG3A 1JKYA 1GXZA 2C8HA 1PWVA 1QS1A 3BW8A 4H0YA 4ELNA 2WN7A 2C8CA 1G24A 4H0VA 3NTSA 4FMLA 2C8GA 5BWMB 2C8BX 1PWQA 2C8EE 4GF1A 5GTTA 3U0JA 2GWLA 2A9KB 1GXYA 2J3XA 4TR5A 1R4BA 2J3VA 4PKVA 4XM6A 4XSGB 1J7NA 4PKSA 5D1SA 4PKWA 5D1TA 2C8DA 4FK7A 5H04A 1UZIA 4PKRA 4H03A 2WN8A 4WF6A 1PWPA 4PKTA 1GY0A 5DZQA 4GY2A 4XM8A 1R45A 1GIQA 2C8FE 1GZFA 3BUZA 4XM7A 4FXQA 4PKQA 1PWWA 2WN6A 1GIRA
chains in the Genus database with same CATH superfamily
1YQYA 2A78B 5D1UA 4DV8A 4XSHB 5H03A 1QS2A 1OJQA 1ZXVA 1OJZA 4H0XA 2WN4A 1PWUA 1OG4A 4H0TA 2C8AA 2WN5A 2GWMA 1OG1A 1GZEA 2J3ZA 2C89A 4PKUA 2BOVB 1OG3A 1JKYA 1GXZA 2C8HA 1PWVA 1QS1A 3BW8A 4H0YA 4ELNA 2WN7A 2C8CA 1G24A 4H0VA 3NTSA 4FMLA 2C8GA 5BWMB 2C8BX 1PWQA 2C8EE 4GF1A 5GTTA 3U0JA 2GWLA 2A9KB 1GXYA 2J3XA 4TR5A 1R4BA 2J3VA 4PKVA 4XM6A 4XSGB 1J7NA 4PKSA 5D1SA 4PKWA 5D1TA 2C8DA 4FK7A 5H04A 1UZIA 4PKRA 4H03A 2WN8A 4WF6A 1PWPA 4PKTA 1GY0A 5DZQA 4GY2A 4XM8A 1R45A 1GIQA 2C8FE 1GZFA 3BUZA 4XM7A 4FXQA 4PKQA 1PWWA 2WN6A 1GIRA
chains in the Genus database with same CATH topology
1YQYA 2A78B 5D1UA 4DV8A 4XSHB 5H03A 1QS2A 1OJQA 1ZXVA 1OJZA 4H0XA 2WN4A 1PWUA 1OG4A 4H0TA 2C8AA 2WN5A 2GWMA 1OG1A 1GZEA 2J3ZA 2C89A 4PKUA 2BOVB 1OG3A 1JKYA 1GXZA 2C8HA 1PWVA 1QS1A 3BW8A 4H0YA 4ELNA 2WN7A 2C8CA 1G24A 4H0VA 3NTSA 4FMLA 2C8GA 5BWMB 2C8BX 1PWQA 2C8EE 4GF1A 5GTTA 3U0JA 2GWLA 2A9KB 1GXYA 2J3XA 4TR5A 1R4BA 2J3VA 4PKVA 4XM6A 4XSGB 1J7NA 4PKSA 5D1SA 4PKWA 5D1TA 2C8DA 4FK7A 5H04A 1UZIA 4PKRA 4H03A 2WN8A 4WF6A 1PWPA 4PKTA 1GY0A 5DZQA 4GY2A 4XM8A 1R45A 1GIQA 2C8FE 1GZFA 3BUZA 4XM7A 4FXQA 4PKQA 1PWWA 2WN6A 1GIRA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1YQY A;  2A78 B;  5D1U A;  4DV8 A;  4XSH B;  5H03 A;  1QS2 A;  1OJQ A;  1ZXV A;  1OJZ A;  4H0X A;  2WN4 A;  1PWU A;  1OG4 A;  4H0T A;  2C8A A;  2WN5 A;  2GWM A;  1OG1 A;  1GZE A;  2J3Z A;  2C89 A;  4PKU A;  2BOV B;  1OG3 A;  1JKY A;  1GXZ A;  2C8H A;  1PWV A;  1QS1 A;  3BW8 A;  4H0Y A;  4ELN A;  2WN7 A;  2C8C A;  1G24 A;  4H0V A;  3NTS A;  4FML A;  2C8G A;  5BWM B;  2C8B X;  1PWQ A;  2C8E E;  4GF1 A;  5GTT A;  3U0J A;  2GWL A;  2A9K B;  1GXY A;  2J3X A;  4TR5 A;  1R4B A;  2J3V A;  4PKV A;  4XM6 A;  4XSG B;  1J7N A;  4PKS A;  5D1S A;  4PKW A;  5D1T A;  2C8D A;  4FK7 A;  5H04 A;  1UZI A;  4PKR A;  4H03 A;  2WN8 A;  4WF6 A;  1PWP A;  4PKT A;  1GY0 A;  5DZQ A;  4GY2 A;  4XM8 A;  1R45 A;  1GIQ A;  2C8F E;  1GZF A;  3BUZ A;  4XM7 A;  4FXQ A;  4PKQ A;  1PWW A;  2WN6 A;  1GIR A; 
#chains in the Genus database with same CATH topology
 1YQY A;  2A78 B;  5D1U A;  4DV8 A;  4XSH B;  5H03 A;  1QS2 A;  1OJQ A;  1ZXV A;  1OJZ A;  4H0X A;  2WN4 A;  1PWU A;  1OG4 A;  4H0T A;  2C8A A;  2WN5 A;  2GWM A;  1OG1 A;  1GZE A;  2J3Z A;  2C89 A;  4PKU A;  2BOV B;  1OG3 A;  1JKY A;  1GXZ A;  2C8H A;  1PWV A;  1QS1 A;  3BW8 A;  4H0Y A;  4ELN A;  2WN7 A;  2C8C A;  1G24 A;  4H0V A;  3NTS A;  4FML A;  2C8G A;  5BWM B;  2C8B X;  1PWQ A;  2C8E E;  4GF1 A;  5GTT A;  3U0J A;  2GWL A;  2A9K B;  1GXY A;  2J3X A;  4TR5 A;  1R4B A;  2J3V A;  4PKV A;  4XM6 A;  4XSG B;  1J7N A;  4PKS A;  5D1S A;  4PKW A;  5D1T A;  2C8D A;  4FK7 A;  5H04 A;  1UZI A;  4PKR A;  4H03 A;  2WN8 A;  4WF6 A;  1PWP A;  4PKT A;  1GY0 A;  5DZQ A;  4GY2 A;  4XM8 A;  1R45 A;  1GIQ A;  2C8F E;  1GZF A;  3BUZ A;  4XM7 A;  4FXQ A;  4PKQ A;  1PWW A;  2WN6 A;  1GIR A; 
#chains in the Genus database with same CATH homology
 1YQY A;  2A78 B;  5D1U A;  4DV8 A;  4XSH B;  5H03 A;  1QS2 A;  1OJQ A;  1ZXV A;  1OJZ A;  4H0X A;  2WN4 A;  1PWU A;  1OG4 A;  4H0T A;  2C8A A;  2WN5 A;  2GWM A;  1OG1 A;  1GZE A;  2J3Z A;  2C89 A;  4PKU A;  2BOV B;  1OG3 A;  1JKY A;  1GXZ A;  2C8H A;  1PWV A;  1QS1 A;  3BW8 A;  4H0Y A;  4ELN A;  2WN7 A;  2C8C A;  1G24 A;  4H0V A;  3NTS A;  4FML A;  2C8G A;  5BWM B;  2C8B X;  1PWQ A;  2C8E E;  4GF1 A;  5GTT A;  3U0J A;  2GWL A;  2A9K B;  1GXY A;  2J3X A;  4TR5 A;  1R4B A;  2J3V A;  4PKV A;  4XM6 A;  4XSG B;  1J7N A;  4PKS A;  5D1S A;  4PKW A;  5D1T A;  2C8D A;  4FK7 A;  5H04 A;  1UZI A;  4PKR A;  4H03 A;  2WN8 A;  4WF6 A;  1PWP A;  4PKT A;  1GY0 A;  5DZQ A;  4GY2 A;  4XM8 A;  1R45 A;  1GIQ A;  2C8F E;  1GZF A;  3BUZ A;  4XM7 A;  4FXQ A;  4PKQ A;  1PWW A;  2WN6 A;  1GIR A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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