4GY2A

Crystal structure of apo-ia-actin complex
Total Genus 137
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
137
sequence length
411
structure length
411
Chain Sequence
IERPEDFLKDKENAIQWEKKEAERVEKNLDTLEKEALELYKKDSEQISNYSQTRQYFYDYQIESNPREKEYKNLRNAISKNKIDKPINVYYFESPEKFAFNKEIRTENQNEISLEKFNELKETIQDKLFKQDGFKDVSLYEPGNGDEKPTPLLIHLKLPKNTGMLPYINSNDVKTLIEQDYSIKIDKIVRIVIEGKQYIKAEASIVNSLDFKDDVSKGDLWGKENYSDWSNKLTPNELADVNDYMRGGYTAINNYLISNGPLNNPNPELDSKVNNIENALKLTPIPSNLIVYRRSGPQEFGLTLTSPEYDFNKIENIDAFKEKWEGKVITYPNFISTSIGSVNMSAFAKRKIILRINIPKDSPGAYLSAIPGYAGEYEVLLNHGSKFKINKVDSYKDGTVTKLILDATLIN
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Arginine ADP-ribosylation mechanism based on structural snapshots of iota-toxin and actin complex
pubmed doi rcsb
molecule tags Toxin/structural protein
source organism Clostridium perfringens
molecule keywords Iota toxin component Ia
total genus 137
structure length 411
sequence length 411
ec nomenclature ec 2.4.2.31: NAD(+)--protein-arginine ADP-ribosyltransferase.
pdb deposition date 2012-09-05

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF03496 ADPrib_exo_Tox ADP-ribosyltransferase exoenzyme
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.176.10 Alpha Beta Alpha-Beta Complex Toxin ADP-ribosyltransferase; Chain A, domain 1 Toxin ADP-ribosyltransferase; Chain A, domain 1 4gy2A02
3.90.176.10 Alpha Beta Alpha-Beta Complex Toxin ADP-ribosyltransferase; Chain A, domain 1 Toxin ADP-ribosyltransferase; Chain A, domain 1 4gy2A01
5GTTA 1YQYA 4DV8A 2C8EE 2C8CA 1PWPA 4GY2A 2J3XA 4FMLA 2J3VA 2C8HA 4H0TA 4PKVA 2J3ZA 2C8BX 1OG1A 1OG3A 2C8DA 2A78B 4XSGB 2BOVB 4H0YA 1G24A 4GF1A 2C89A 3U0JA 1JKYA 1PWVA 4H0XA 1QS1A 2WN5A 5H04A 1QS2A 4ELNA 5D1TA 1OJQA 5H03A 1ZXVA 5DZQA 1GY0A 1PWQA 1GXYA 4PKUA 4XM8A 2GWLA 4XM7A 2WN8A 5D1UA 2C8GA 1R4BA 2GWMA 4PKRA 4TR5A 4FXQA 1GZFA 2A9KB 4H03A 4WF6A 4XM6A 4PKSA 2WN7A 1GIQA 2WN4A 2WN6A 1GXZA 4FK7A 2C8FE 3BUZA 2C8AA 1J7NA 4H0VA 1PWUA 3BW8A 1OJZA 4PKQA 1R45A 4PKWA 4XSHB 1GIRA 1OG4A 5BWMB 1PWWA 5D1SA 1GZEA 3NTSA 1UZIA 4PKTA
chains in the Genus database with same CATH superfamily
5GTTA 1YQYA 4DV8A 2C8EE 2C8CA 1PWPA 4GY2A 2J3XA 4FMLA 2J3VA 2C8HA 4H0TA 4PKVA 2J3ZA 2C8BX 1OG1A 1OG3A 2C8DA 2A78B 4XSGB 2BOVB 4H0YA 1G24A 4GF1A 2C89A 3U0JA 1JKYA 1PWVA 4H0XA 1QS1A 2WN5A 5H04A 1QS2A 4ELNA 5D1TA 1OJQA 5H03A 1ZXVA 5DZQA 1GY0A 1PWQA 1GXYA 4PKUA 4XM8A 2GWLA 4XM7A 2WN8A 5D1UA 2C8GA 1R4BA 2GWMA 4PKRA 4TR5A 4FXQA 1GZFA 2A9KB 4H03A 4WF6A 4XM6A 4PKSA 2WN7A 1GIQA 2WN4A 2WN6A 1GXZA 4FK7A 2C8FE 3BUZA 2C8AA 1J7NA 4H0VA 1PWUA 3BW8A 1OJZA 4PKQA 1R45A 4PKWA 4XSHB 1GIRA 1OG4A 5BWMB 1PWWA 5D1SA 1GZEA 3NTSA 1UZIA 4PKTA
chains in the Genus database with same CATH topology
5GTTA 1YQYA 4DV8A 2C8EE 2C8CA 1PWPA 4GY2A 2J3XA 4FMLA 2J3VA 2C8HA 4H0TA 4PKVA 2J3ZA 2C8BX 1OG1A 1OG3A 2C8DA 2A78B 4XSGB 2BOVB 4H0YA 1G24A 4GF1A 2C89A 3U0JA 1JKYA 1PWVA 4H0XA 1QS1A 2WN5A 5H04A 1QS2A 4ELNA 5D1TA 1OJQA 5H03A 1ZXVA 5DZQA 1GY0A 1PWQA 1GXYA 4PKUA 4XM8A 2GWLA 4XM7A 2WN8A 5D1UA 2C8GA 1R4BA 2GWMA 4PKRA 4TR5A 4FXQA 1GZFA 2A9KB 4H03A 4WF6A 4XM6A 4PKSA 2WN7A 1GIQA 2WN4A 2WN6A 1GXZA 4FK7A 2C8FE 3BUZA 2C8AA 1J7NA 4H0VA 1PWUA 3BW8A 1OJZA 4PKQA 1R45A 4PKWA 4XSHB 1GIRA 1OG4A 5BWMB 1PWWA 5D1SA 1GZEA 3NTSA 1UZIA 4PKTA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 5GTT A;  1YQY A;  4DV8 A;  2C8E E;  2C8C A;  1PWP A;  4GY2 A;  2J3X A;  4FML A;  2J3V A;  2C8H A;  4H0T A;  4PKV A;  2J3Z A;  2C8B X;  1OG1 A;  1OG3 A;  2C8D A;  2A78 B;  4XSG B;  2BOV B;  4H0Y A;  1G24 A;  4GF1 A;  2C89 A;  3U0J A;  1JKY A;  1PWV A;  4H0X A;  1QS1 A;  2WN5 A;  5H04 A;  1QS2 A;  4ELN A;  5D1T A;  1OJQ A;  5H03 A;  1ZXV A;  5DZQ A;  1GY0 A;  1PWQ A;  1GXY A;  4PKU A;  4XM8 A;  2GWL A;  4XM7 A;  2WN8 A;  5D1U A;  2C8G A;  1R4B A;  2GWM A;  4PKR A;  4TR5 A;  4FXQ A;  1GZF A;  2A9K B;  4H03 A;  4WF6 A;  4XM6 A;  4PKS A;  2WN7 A;  1GIQ A;  2WN4 A;  2WN6 A;  1GXZ A;  4FK7 A;  2C8F E;  3BUZ A;  2C8A A;  1J7N A;  4H0V A;  1PWU A;  3BW8 A;  1OJZ A;  4PKQ A;  1R45 A;  4PKW A;  4XSH B;  1GIR A;  1OG4 A;  5BWM B;  1PWW A;  5D1S A;  1GZE A;  3NTS A;  1UZI A;  4PKT A; 
#chains in the Genus database with same CATH topology
 5GTT A;  1YQY A;  4DV8 A;  2C8E E;  2C8C A;  1PWP A;  4GY2 A;  2J3X A;  4FML A;  2J3V A;  2C8H A;  4H0T A;  4PKV A;  2J3Z A;  2C8B X;  1OG1 A;  1OG3 A;  2C8D A;  2A78 B;  4XSG B;  2BOV B;  4H0Y A;  1G24 A;  4GF1 A;  2C89 A;  3U0J A;  1JKY A;  1PWV A;  4H0X A;  1QS1 A;  2WN5 A;  5H04 A;  1QS2 A;  4ELN A;  5D1T A;  1OJQ A;  5H03 A;  1ZXV A;  5DZQ A;  1GY0 A;  1PWQ A;  1GXY A;  4PKU A;  4XM8 A;  2GWL A;  4XM7 A;  2WN8 A;  5D1U A;  2C8G A;  1R4B A;  2GWM A;  4PKR A;  4TR5 A;  4FXQ A;  1GZF A;  2A9K B;  4H03 A;  4WF6 A;  4XM6 A;  4PKS A;  2WN7 A;  1GIQ A;  2WN4 A;  2WN6 A;  1GXZ A;  4FK7 A;  2C8F E;  3BUZ A;  2C8A A;  1J7N A;  4H0V A;  1PWU A;  3BW8 A;  1OJZ A;  4PKQ A;  1R45 A;  4PKW A;  4XSH B;  1GIR A;  1OG4 A;  5BWM B;  1PWW A;  5D1S A;  1GZE A;  3NTS A;  1UZI A;  4PKT A; 
#chains in the Genus database with same CATH homology
 5GTT A;  1YQY A;  4DV8 A;  2C8E E;  2C8C A;  1PWP A;  4GY2 A;  2J3X A;  4FML A;  2J3V A;  2C8H A;  4H0T A;  4PKV A;  2J3Z A;  2C8B X;  1OG1 A;  1OG3 A;  2C8D A;  2A78 B;  4XSG B;  2BOV B;  4H0Y A;  1G24 A;  4GF1 A;  2C89 A;  3U0J A;  1JKY A;  1PWV A;  4H0X A;  1QS1 A;  2WN5 A;  5H04 A;  1QS2 A;  4ELN A;  5D1T A;  1OJQ A;  5H03 A;  1ZXV A;  5DZQ A;  1GY0 A;  1PWQ A;  1GXY A;  4PKU A;  4XM8 A;  2GWL A;  4XM7 A;  2WN8 A;  5D1U A;  2C8G A;  1R4B A;  2GWM A;  4PKR A;  4TR5 A;  4FXQ A;  1GZF A;  2A9K B;  4H03 A;  4WF6 A;  4XM6 A;  4PKS A;  2WN7 A;  1GIQ A;  2WN4 A;  2WN6 A;  1GXZ A;  4FK7 A;  2C8F E;  3BUZ A;  2C8A A;  1J7N A;  4H0V A;  1PWU A;  3BW8 A;  1OJZ A;  4PKQ A;  1R45 A;  4PKW A;  4XSH B;  1GIR A;  1OG4 A;  5BWM B;  1PWW A;  5D1S A;  1GZE A;  3NTS A;  1UZI A;  4PKT A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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