4H03A

Crystal structure of nad+-ia-actin complex
Total Genus 147
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
147
sequence length
414
structure length
414
Chain Sequence
MAFIERPEDFLKDKENAIQWEKKEAERVEKNLDTLEKEALELYKKDSEQISNYSQTRQYFYDYQIESNPREKEYKNLRNAISKNKIDKPINVYYFESPEKFAFNKEIRTENQNEISLEKFNELKETIQDKLFKQDGFKDVSLYEPGNGDEKPTPLLIHLKLPKNTGMLPYINSNDVKTLIEQDYSIKIDKIVRIVIEGKQYIKAEASIVNSLDFKDDVSKGDLWGKENYSDWSNKLTPNELADVNDYMRGGYTAINNYLISNGPLNNPNPELDSKVNNIENALKLTPIPSNLIVYRRSGPQEFGLTLTSPEYDFNKIENIDAFKEKWEGKVITYPNFISTSIGSVNMSAFAKRKIILRINIPKDSPGAYLSAIPGYAGEYEVLLNHGSKFKINKVDSYKDGTVTKLILDATLIN
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Toxin/structural protein
source organism Clostridium perfringens
publication title Arginine ADP-ribosylation mechanism based on structural snapshots of iota-toxin and actin complex
pubmed doi rcsb
molecule keywords Iota toxin component Ia
total genus 147
structure length 414
sequence length 414
ec nomenclature ec 2.4.2.31: NAD(+)--protein-arginine ADP-ribosyltransferase.
pdb deposition date 2012-09-07

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF03496 ADPrib_exo_Tox ADP-ribosyltransferase exoenzyme
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.176.10 Alpha Beta Alpha-Beta Complex Toxin ADP-ribosyltransferase; Chain A, domain 1 Toxin ADP-ribosyltransferase; Chain A, domain 1 4h03A02
3.90.176.10 Alpha Beta Alpha-Beta Complex Toxin ADP-ribosyltransferase; Chain A, domain 1 Toxin ADP-ribosyltransferase; Chain A, domain 1 4h03A01
2BOVB 2WN6A 4PKVA 1G24A 1PWWA 4H0TA 5BWMB 1J7NA 1UZIA 3U0JA 2C8AA 1GZEA 4H0XA 2C8GA 2WN7A 1QS2A 4TR5A 1OG4A 1OG3A 1GXYA 1JKYA 4H0YA 1YQYA 1QS1A 5GTTA 5H04A 4H0VA 2C8FE 5D1UA 2WN4A 4PKSA 1GY0A 4FMLA 2C8CA 4PKRA 2GWLA 4PKQA 4PKTA 2J3VA 3BUZA 4ELNA 5D1SA 2C8EE 4PKUA 2GWMA 4DV8A 1OG1A 4WF6A 4XM6A 1OJQA 5H03A 2J3XA 2A9KB 1ZXVA 3BW8A 1PWUA 2WN5A 4GF1A 1GIQA 4PKWA 4H03A 1PWPA 1OJZA 1R45A 2J3ZA 5D1TA 4FK7A 4XSHB 1GIRA 1GZFA 4XM7A 3NTSA 2C8HA 2WN8A 4XM8A 4GY2A 4FXQA 2C8DA 1PWQA 1R4BA 2A78B 4XSGB 1PWVA 1GXZA 2C89A 5DZQA 2C8BX
chains in the Genus database with same CATH superfamily
2BOVB 2WN6A 4PKVA 1G24A 1PWWA 4H0TA 5BWMB 1J7NA 1UZIA 3U0JA 2C8AA 1GZEA 4H0XA 2C8GA 2WN7A 1QS2A 4TR5A 1OG4A 1OG3A 1GXYA 1JKYA 4H0YA 1YQYA 1QS1A 5GTTA 5H04A 4H0VA 2C8FE 5D1UA 2WN4A 4PKSA 1GY0A 4FMLA 2C8CA 4PKRA 2GWLA 4PKQA 4PKTA 2J3VA 3BUZA 4ELNA 5D1SA 2C8EE 4PKUA 2GWMA 4DV8A 1OG1A 4WF6A 4XM6A 1OJQA 5H03A 2J3XA 2A9KB 1ZXVA 3BW8A 1PWUA 2WN5A 4GF1A 1GIQA 4PKWA 4H03A 1PWPA 1OJZA 1R45A 2J3ZA 5D1TA 4FK7A 4XSHB 1GIRA 1GZFA 4XM7A 3NTSA 2C8HA 2WN8A 4XM8A 4GY2A 4FXQA 2C8DA 1PWQA 1R4BA 2A78B 4XSGB 1PWVA 1GXZA 2C89A 5DZQA 2C8BX
chains in the Genus database with same CATH topology
2BOVB 2WN6A 4PKVA 1G24A 1PWWA 4H0TA 5BWMB 1J7NA 1UZIA 3U0JA 2C8AA 1GZEA 4H0XA 2C8GA 2WN7A 1QS2A 4TR5A 1OG4A 1OG3A 1GXYA 1JKYA 4H0YA 1YQYA 1QS1A 5GTTA 5H04A 4H0VA 2C8FE 5D1UA 2WN4A 4PKSA 1GY0A 4FMLA 2C8CA 4PKRA 2GWLA 4PKQA 4PKTA 2J3VA 3BUZA 4ELNA 5D1SA 2C8EE 4PKUA 2GWMA 4DV8A 1OG1A 4WF6A 4XM6A 1OJQA 5H03A 2J3XA 2A9KB 1ZXVA 3BW8A 1PWUA 2WN5A 4GF1A 1GIQA 4PKWA 4H03A 1PWPA 1OJZA 1R45A 2J3ZA 5D1TA 4FK7A 4XSHB 1GIRA 1GZFA 4XM7A 3NTSA 2C8HA 2WN8A 4XM8A 4GY2A 4FXQA 2C8DA 1PWQA 1R4BA 2A78B 4XSGB 1PWVA 1GXZA 2C89A 5DZQA 2C8BX
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2BOV B;  2WN6 A;  4PKV A;  1G24 A;  1PWW A;  4H0T A;  5BWM B;  1J7N A;  1UZI A;  3U0J A;  2C8A A;  1GZE A;  4H0X A;  2C8G A;  2WN7 A;  1QS2 A;  4TR5 A;  1OG4 A;  1OG3 A;  1GXY A;  1JKY A;  4H0Y A;  1YQY A;  1QS1 A;  5GTT A;  5H04 A;  4H0V A;  2C8F E;  5D1U A;  2WN4 A;  4PKS A;  1GY0 A;  4FML A;  2C8C A;  4PKR A;  2GWL A;  4PKQ A;  4PKT A;  2J3V A;  3BUZ A;  4ELN A;  5D1S A;  2C8E E;  4PKU A;  2GWM A;  4DV8 A;  1OG1 A;  4WF6 A;  4XM6 A;  1OJQ A;  5H03 A;  2J3X A;  2A9K B;  1ZXV A;  3BW8 A;  1PWU A;  2WN5 A;  4GF1 A;  1GIQ A;  4PKW A;  4H03 A;  1PWP A;  1OJZ A;  1R45 A;  2J3Z A;  5D1T A;  4FK7 A;  4XSH B;  1GIR A;  1GZF A;  4XM7 A;  3NTS A;  2C8H A;  2WN8 A;  4XM8 A;  4GY2 A;  4FXQ A;  2C8D A;  1PWQ A;  1R4B A;  2A78 B;  4XSG B;  1PWV A;  1GXZ A;  2C89 A;  5DZQ A;  2C8B X; 
#chains in the Genus database with same CATH topology
 2BOV B;  2WN6 A;  4PKV A;  1G24 A;  1PWW A;  4H0T A;  5BWM B;  1J7N A;  1UZI A;  3U0J A;  2C8A A;  1GZE A;  4H0X A;  2C8G A;  2WN7 A;  1QS2 A;  4TR5 A;  1OG4 A;  1OG3 A;  1GXY A;  1JKY A;  4H0Y A;  1YQY A;  1QS1 A;  5GTT A;  5H04 A;  4H0V A;  2C8F E;  5D1U A;  2WN4 A;  4PKS A;  1GY0 A;  4FML A;  2C8C A;  4PKR A;  2GWL A;  4PKQ A;  4PKT A;  2J3V A;  3BUZ A;  4ELN A;  5D1S A;  2C8E E;  4PKU A;  2GWM A;  4DV8 A;  1OG1 A;  4WF6 A;  4XM6 A;  1OJQ A;  5H03 A;  2J3X A;  2A9K B;  1ZXV A;  3BW8 A;  1PWU A;  2WN5 A;  4GF1 A;  1GIQ A;  4PKW A;  4H03 A;  1PWP A;  1OJZ A;  1R45 A;  2J3Z A;  5D1T A;  4FK7 A;  4XSH B;  1GIR A;  1GZF A;  4XM7 A;  3NTS A;  2C8H A;  2WN8 A;  4XM8 A;  4GY2 A;  4FXQ A;  2C8D A;  1PWQ A;  1R4B A;  2A78 B;  4XSG B;  1PWV A;  1GXZ A;  2C89 A;  5DZQ A;  2C8B X; 
#chains in the Genus database with same CATH homology
 2BOV B;  2WN6 A;  4PKV A;  1G24 A;  1PWW A;  4H0T A;  5BWM B;  1J7N A;  1UZI A;  3U0J A;  2C8A A;  1GZE A;  4H0X A;  2C8G A;  2WN7 A;  1QS2 A;  4TR5 A;  1OG4 A;  1OG3 A;  1GXY A;  1JKY A;  4H0Y A;  1YQY A;  1QS1 A;  5GTT A;  5H04 A;  4H0V A;  2C8F E;  5D1U A;  2WN4 A;  4PKS A;  1GY0 A;  4FML A;  2C8C A;  4PKR A;  2GWL A;  4PKQ A;  4PKT A;  2J3V A;  3BUZ A;  4ELN A;  5D1S A;  2C8E E;  4PKU A;  2GWM A;  4DV8 A;  1OG1 A;  4WF6 A;  4XM6 A;  1OJQ A;  5H03 A;  2J3X A;  2A9K B;  1ZXV A;  3BW8 A;  1PWU A;  2WN5 A;  4GF1 A;  1GIQ A;  4PKW A;  4H03 A;  1PWP A;  1OJZ A;  1R45 A;  2J3Z A;  5D1T A;  4FK7 A;  4XSH B;  1GIR A;  1GZF A;  4XM7 A;  3NTS A;  2C8H A;  2WN8 A;  4XM8 A;  4GY2 A;  4FXQ A;  2C8D A;  1PWQ A;  1R4B A;  2A78 B;  4XSG B;  1PWV A;  1GXZ A;  2C89 A;  5DZQ A;  2C8B X; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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