4H0TA

Crystal structure of ia-adpr-actin complex
Total Genus 143
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
143
sequence length
414
structure length
414
Chain Sequence
MAFIERPEDFLKDKENAIQWEKKEAERVEKNLDTLEKEALELYKKDSEQISNYSQTRQYFYDYQIESNPREKEYKNLRNAISKNKIDKPINVYYFESPEKFAFNKEIRTENQNEISLEKFNELKETIQDKLFKQDGFKDVSLYEPGNGDEKPTPLLIHLKLPKNTGMLPYINSNDVKTLIEQDYSIKIDKIVRIVIEGKQYIKAEASIVNSLDFKDDVSKGDLWGKENYSDWSNKLTPNELADVNDYMRGGYTAINNYLISNGPLNNPNPELDSKVNNIENALKLTPIPSNLIVYRRSGPQEFGLTLTSPEYDFNKIENIDAFKEKWEGKVITYPNFISTSIGSVNMSAFAKRKIILRINIPKDSPGAYLSAIPGYAGEYEVLLNHGSKFKINKVDSYKDGTVTKLILDATLIN
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Toxin/structural protein
source organism Clostridium perfringens
publication title Arginine ADP-ribosylation mechanism based on structural snapshots of iota-toxin and actin complex
pubmed doi rcsb
molecule keywords Iota toxin component Ia
total genus 143
structure length 414
sequence length 414
ec nomenclature ec 2.4.2.31: NAD(+)--protein-arginine ADP-ribosyltransferase.
pdb deposition date 2012-09-10

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF03496 ADPrib_exo_Tox ADP-ribosyltransferase exoenzyme
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.176.10 Alpha Beta Alpha-Beta Complex Toxin ADP-ribosyltransferase; Chain A, domain 1 Toxin ADP-ribosyltransferase; Chain A, domain 1 4h0tA02
3.90.176.10 Alpha Beta Alpha-Beta Complex Toxin ADP-ribosyltransferase; Chain A, domain 1 Toxin ADP-ribosyltransferase; Chain A, domain 1 4h0tA01
1GIRA 4PKRA 3BW8A 4H0XA 1QS2A 2C8GA 2J3VA 1PWUA 4WF6A 5BWMB 4FMLA 2J3XA 2BOVB 4XM8A 4H0TA 2J3ZA 1UZIA 2WN7A 5H04A 1OG4A 2C8AA 4FK7A 1GIQA 1PWPA 1YQYA 1OG3A 1R4BA 4XSGB 2C8FE 2C8DA 4PKSA 1GXYA 4XM7A 4PKUA 2WN8A 2C8EE 4GF1A 2GWLA 4TR5A 2C8CA 1PWQA 5H03A 1R45A 2A78B 3BUZA 4DV8A 5GTTA 1G24A 5D1SA 1JKYA 1GZEA 4H0YA 1GXZA 4PKTA 4XSHB 2C8BX 1QS1A 2C89A 2WN6A 1PWWA 4ELNA 4H03A 5DZQA 4H0VA 2GWMA 4PKWA 2WN4A 1OJQA 5D1TA 4XM6A 4PKVA 1J7NA 3NTSA 2WN5A 1GY0A 2C8HA 1ZXVA 2A9KB 4GY2A 5D1UA 4FXQA 1OJZA 1PWVA 1GZFA 3U0JA 4PKQA 1OG1A
chains in the Genus database with same CATH superfamily
1GIRA 4PKRA 3BW8A 4H0XA 1QS2A 2C8GA 2J3VA 1PWUA 4WF6A 5BWMB 4FMLA 2J3XA 2BOVB 4XM8A 4H0TA 2J3ZA 1UZIA 2WN7A 5H04A 1OG4A 2C8AA 4FK7A 1GIQA 1PWPA 1YQYA 1OG3A 1R4BA 4XSGB 2C8FE 2C8DA 4PKSA 1GXYA 4XM7A 4PKUA 2WN8A 2C8EE 4GF1A 2GWLA 4TR5A 2C8CA 1PWQA 5H03A 1R45A 2A78B 3BUZA 4DV8A 5GTTA 1G24A 5D1SA 1JKYA 1GZEA 4H0YA 1GXZA 4PKTA 4XSHB 2C8BX 1QS1A 2C89A 2WN6A 1PWWA 4ELNA 4H03A 5DZQA 4H0VA 2GWMA 4PKWA 2WN4A 1OJQA 5D1TA 4XM6A 4PKVA 1J7NA 3NTSA 2WN5A 1GY0A 2C8HA 1ZXVA 2A9KB 4GY2A 5D1UA 4FXQA 1OJZA 1PWVA 1GZFA 3U0JA 4PKQA 1OG1A
chains in the Genus database with same CATH topology
1GIRA 4PKRA 3BW8A 4H0XA 1QS2A 2C8GA 2J3VA 1PWUA 4WF6A 5BWMB 4FMLA 2J3XA 2BOVB 4XM8A 4H0TA 2J3ZA 1UZIA 2WN7A 5H04A 1OG4A 2C8AA 4FK7A 1GIQA 1PWPA 1YQYA 1OG3A 1R4BA 4XSGB 2C8FE 2C8DA 4PKSA 1GXYA 4XM7A 4PKUA 2WN8A 2C8EE 4GF1A 2GWLA 4TR5A 2C8CA 1PWQA 5H03A 1R45A 2A78B 3BUZA 4DV8A 5GTTA 1G24A 5D1SA 1JKYA 1GZEA 4H0YA 1GXZA 4PKTA 4XSHB 2C8BX 1QS1A 2C89A 2WN6A 1PWWA 4ELNA 4H03A 5DZQA 4H0VA 2GWMA 4PKWA 2WN4A 1OJQA 5D1TA 4XM6A 4PKVA 1J7NA 3NTSA 2WN5A 1GY0A 2C8HA 1ZXVA 2A9KB 4GY2A 5D1UA 4FXQA 1OJZA 1PWVA 1GZFA 3U0JA 4PKQA 1OG1A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1GIR A;  4PKR A;  3BW8 A;  4H0X A;  1QS2 A;  2C8G A;  2J3V A;  1PWU A;  4WF6 A;  5BWM B;  4FML A;  2J3X A;  2BOV B;  4XM8 A;  4H0T A;  2J3Z A;  1UZI A;  2WN7 A;  5H04 A;  1OG4 A;  2C8A A;  4FK7 A;  1GIQ A;  1PWP A;  1YQY A;  1OG3 A;  1R4B A;  4XSG B;  2C8F E;  2C8D A;  4PKS A;  1GXY A;  4XM7 A;  4PKU A;  2WN8 A;  2C8E E;  4GF1 A;  2GWL A;  4TR5 A;  2C8C A;  1PWQ A;  5H03 A;  1R45 A;  2A78 B;  3BUZ A;  4DV8 A;  5GTT A;  1G24 A;  5D1S A;  1JKY A;  1GZE A;  4H0Y A;  1GXZ A;  4PKT A;  4XSH B;  2C8B X;  1QS1 A;  2C89 A;  2WN6 A;  1PWW A;  4ELN A;  4H03 A;  5DZQ A;  4H0V A;  2GWM A;  4PKW A;  2WN4 A;  1OJQ A;  5D1T A;  4XM6 A;  4PKV A;  1J7N A;  3NTS A;  2WN5 A;  1GY0 A;  2C8H A;  1ZXV A;  2A9K B;  4GY2 A;  5D1U A;  4FXQ A;  1OJZ A;  1PWV A;  1GZF A;  3U0J A;  4PKQ A;  1OG1 A; 
#chains in the Genus database with same CATH topology
 1GIR A;  4PKR A;  3BW8 A;  4H0X A;  1QS2 A;  2C8G A;  2J3V A;  1PWU A;  4WF6 A;  5BWM B;  4FML A;  2J3X A;  2BOV B;  4XM8 A;  4H0T A;  2J3Z A;  1UZI A;  2WN7 A;  5H04 A;  1OG4 A;  2C8A A;  4FK7 A;  1GIQ A;  1PWP A;  1YQY A;  1OG3 A;  1R4B A;  4XSG B;  2C8F E;  2C8D A;  4PKS A;  1GXY A;  4XM7 A;  4PKU A;  2WN8 A;  2C8E E;  4GF1 A;  2GWL A;  4TR5 A;  2C8C A;  1PWQ A;  5H03 A;  1R45 A;  2A78 B;  3BUZ A;  4DV8 A;  5GTT A;  1G24 A;  5D1S A;  1JKY A;  1GZE A;  4H0Y A;  1GXZ A;  4PKT A;  4XSH B;  2C8B X;  1QS1 A;  2C89 A;  2WN6 A;  1PWW A;  4ELN A;  4H03 A;  5DZQ A;  4H0V A;  2GWM A;  4PKW A;  2WN4 A;  1OJQ A;  5D1T A;  4XM6 A;  4PKV A;  1J7N A;  3NTS A;  2WN5 A;  1GY0 A;  2C8H A;  1ZXV A;  2A9K B;  4GY2 A;  5D1U A;  4FXQ A;  1OJZ A;  1PWV A;  1GZF A;  3U0J A;  4PKQ A;  1OG1 A; 
#chains in the Genus database with same CATH homology
 1GIR A;  4PKR A;  3BW8 A;  4H0X A;  1QS2 A;  2C8G A;  2J3V A;  1PWU A;  4WF6 A;  5BWM B;  4FML A;  2J3X A;  2BOV B;  4XM8 A;  4H0T A;  2J3Z A;  1UZI A;  2WN7 A;  5H04 A;  1OG4 A;  2C8A A;  4FK7 A;  1GIQ A;  1PWP A;  1YQY A;  1OG3 A;  1R4B A;  4XSG B;  2C8F E;  2C8D A;  4PKS A;  1GXY A;  4XM7 A;  4PKU A;  2WN8 A;  2C8E E;  4GF1 A;  2GWL A;  4TR5 A;  2C8C A;  1PWQ A;  5H03 A;  1R45 A;  2A78 B;  3BUZ A;  4DV8 A;  5GTT A;  1G24 A;  5D1S A;  1JKY A;  1GZE A;  4H0Y A;  1GXZ A;  4PKT A;  4XSH B;  2C8B X;  1QS1 A;  2C89 A;  2WN6 A;  1PWW A;  4ELN A;  4H03 A;  5DZQ A;  4H0V A;  2GWM A;  4PKW A;  2WN4 A;  1OJQ A;  5D1T A;  4XM6 A;  4PKV A;  1J7N A;  3NTS A;  2WN5 A;  1GY0 A;  2C8H A;  1ZXV A;  2A9K B;  4GY2 A;  5D1U A;  4FXQ A;  1OJZ A;  1PWV A;  1GZF A;  3U0J A;  4PKQ A;  1OG1 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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