4H0XA

Crystal structure of nad+-ia(e380a)-actin complex
Total Genus 139
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
139
sequence length
413
structure length
413
Chain Sequence
AFIERPEDFLKDKENAIQWEKKEAERVEKNLDTLEKEALELYKKDSEQISNYSQTRQYFYDYQIESNPREKEYKNLRNAISKNKIDKPINVYYFESPEKFAFNKEIRTENQNEISLEKFNELKETIQDKLFKQDGFKDVSLYEPGNGDEKPTPLLIHLKLPKNTGMLPYINSNDVKTLIEQDYSIKIDKIVRIVIEGKQYIKAEASIVNSLDFKDDVSKGDLWGKENYSDWSNKLTPNELADVNDYMRGGYTAINNYLISNGPLNNPNPELDSKVNNIENALKLTPIPSNLIVYRRSGPQEFGLTLTSPEYDFNKIENIDAFKEKWEGKVITYPNFISTSIGSVNMSAFAKRKIILRINIPKDSPGAYLSAIPGYAGEYAVLLNHGSKFKINKVDSYKDGTVTKLILDATLIN
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Arginine ADP-ribosylation mechanism based on structural snapshots of iota-toxin and actin complex
pubmed doi rcsb
molecule tags Toxin/structural protein
source organism Clostridium perfringens
molecule keywords Iota toxin component Ia
total genus 139
structure length 413
sequence length 413
ec nomenclature ec 2.4.2.31: NAD(+)--protein-arginine ADP-ribosyltransferase.
pdb deposition date 2012-09-10

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF03496 ADPrib_exo_Tox ADP-ribosyltransferase exoenzyme
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.176.10 Alpha Beta Alpha-Beta Complex Toxin ADP-ribosyltransferase; Chain A, domain 1 Toxin ADP-ribosyltransferase; Chain A, domain 1 4h0xA02
3.90.176.10 Alpha Beta Alpha-Beta Complex Toxin ADP-ribosyltransferase; Chain A, domain 1 Toxin ADP-ribosyltransferase; Chain A, domain 1 4h0xA01
1GXZA 1PWWA 5H04A 4TR5A 2J3XA 4PKQA 1R4BA 1OG1A 3U0JA 4H0TA 4XSGB 3BUZA 1UZIA 2BOVB 5D1TA 1G24A 2WN7A 1PWUA 2C8DA 2C8BX 2C8AA 5BWMB 4PKUA 4ELNA 2WN8A 1QS2A 2WN5A 2GWMA 4GF1A 2J3VA 4H0XA 1QS1A 1OJZA 4XM8A 4FXQA 2C8HA 4PKWA 1PWPA 4FK7A 1R45A 4PKSA 1OG4A 1GXYA 2C89A 5GTTA 1GY0A 4H0YA 1OJQA 5H03A 5D1SA 4H03A 2A78B 5D1UA 1YQYA 4DV8A 4WF6A 2GWLA 5DZQA 4PKVA 2A9KB 3NTSA 4XM6A 4GY2A 2C8GA 2C8CA 1GZFA 2J3ZA 1GIQA 1ZXVA 1J7NA 4XM7A 2C8FE 3BW8A 4PKTA 4H0VA 1PWVA 1GIRA 1PWQA 1JKYA 1OG3A 4XSHB 4FMLA 2WN4A 2WN6A 4PKRA 2C8EE 1GZEA
chains in the Genus database with same CATH superfamily
1GXZA 1PWWA 5H04A 4TR5A 2J3XA 4PKQA 1R4BA 1OG1A 3U0JA 4H0TA 4XSGB 3BUZA 1UZIA 2BOVB 5D1TA 1G24A 2WN7A 1PWUA 2C8DA 2C8BX 2C8AA 5BWMB 4PKUA 4ELNA 2WN8A 1QS2A 2WN5A 2GWMA 4GF1A 2J3VA 4H0XA 1QS1A 1OJZA 4XM8A 4FXQA 2C8HA 4PKWA 1PWPA 4FK7A 1R45A 4PKSA 1OG4A 1GXYA 2C89A 5GTTA 1GY0A 4H0YA 1OJQA 5H03A 5D1SA 4H03A 2A78B 5D1UA 1YQYA 4DV8A 4WF6A 2GWLA 5DZQA 4PKVA 2A9KB 3NTSA 4XM6A 4GY2A 2C8GA 2C8CA 1GZFA 2J3ZA 1GIQA 1ZXVA 1J7NA 4XM7A 2C8FE 3BW8A 4PKTA 4H0VA 1PWVA 1GIRA 1PWQA 1JKYA 1OG3A 4XSHB 4FMLA 2WN4A 2WN6A 4PKRA 2C8EE 1GZEA
chains in the Genus database with same CATH topology
1GXZA 1PWWA 5H04A 4TR5A 2J3XA 4PKQA 1R4BA 1OG1A 3U0JA 4H0TA 4XSGB 3BUZA 1UZIA 2BOVB 5D1TA 1G24A 2WN7A 1PWUA 2C8DA 2C8BX 2C8AA 5BWMB 4PKUA 4ELNA 2WN8A 1QS2A 2WN5A 2GWMA 4GF1A 2J3VA 4H0XA 1QS1A 1OJZA 4XM8A 4FXQA 2C8HA 4PKWA 1PWPA 4FK7A 1R45A 4PKSA 1OG4A 1GXYA 2C89A 5GTTA 1GY0A 4H0YA 1OJQA 5H03A 5D1SA 4H03A 2A78B 5D1UA 1YQYA 4DV8A 4WF6A 2GWLA 5DZQA 4PKVA 2A9KB 3NTSA 4XM6A 4GY2A 2C8GA 2C8CA 1GZFA 2J3ZA 1GIQA 1ZXVA 1J7NA 4XM7A 2C8FE 3BW8A 4PKTA 4H0VA 1PWVA 1GIRA 1PWQA 1JKYA 1OG3A 4XSHB 4FMLA 2WN4A 2WN6A 4PKRA 2C8EE 1GZEA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1GXZ A;  1PWW A;  5H04 A;  4TR5 A;  2J3X A;  4PKQ A;  1R4B A;  1OG1 A;  3U0J A;  4H0T A;  4XSG B;  3BUZ A;  1UZI A;  2BOV B;  5D1T A;  1G24 A;  2WN7 A;  1PWU A;  2C8D A;  2C8B X;  2C8A A;  5BWM B;  4PKU A;  4ELN A;  2WN8 A;  1QS2 A;  2WN5 A;  2GWM A;  4GF1 A;  2J3V A;  4H0X A;  1QS1 A;  1OJZ A;  4XM8 A;  4FXQ A;  2C8H A;  4PKW A;  1PWP A;  4FK7 A;  1R45 A;  4PKS A;  1OG4 A;  1GXY A;  2C89 A;  5GTT A;  1GY0 A;  4H0Y A;  1OJQ A;  5H03 A;  5D1S A;  4H03 A;  2A78 B;  5D1U A;  1YQY A;  4DV8 A;  4WF6 A;  2GWL A;  5DZQ A;  4PKV A;  2A9K B;  3NTS A;  4XM6 A;  4GY2 A;  2C8G A;  2C8C A;  1GZF A;  2J3Z A;  1GIQ A;  1ZXV A;  1J7N A;  4XM7 A;  2C8F E;  3BW8 A;  4PKT A;  4H0V A;  1PWV A;  1GIR A;  1PWQ A;  1JKY A;  1OG3 A;  4XSH B;  4FML A;  2WN4 A;  2WN6 A;  4PKR A;  2C8E E;  1GZE A; 
#chains in the Genus database with same CATH topology
 1GXZ A;  1PWW A;  5H04 A;  4TR5 A;  2J3X A;  4PKQ A;  1R4B A;  1OG1 A;  3U0J A;  4H0T A;  4XSG B;  3BUZ A;  1UZI A;  2BOV B;  5D1T A;  1G24 A;  2WN7 A;  1PWU A;  2C8D A;  2C8B X;  2C8A A;  5BWM B;  4PKU A;  4ELN A;  2WN8 A;  1QS2 A;  2WN5 A;  2GWM A;  4GF1 A;  2J3V A;  4H0X A;  1QS1 A;  1OJZ A;  4XM8 A;  4FXQ A;  2C8H A;  4PKW A;  1PWP A;  4FK7 A;  1R45 A;  4PKS A;  1OG4 A;  1GXY A;  2C89 A;  5GTT A;  1GY0 A;  4H0Y A;  1OJQ A;  5H03 A;  5D1S A;  4H03 A;  2A78 B;  5D1U A;  1YQY A;  4DV8 A;  4WF6 A;  2GWL A;  5DZQ A;  4PKV A;  2A9K B;  3NTS A;  4XM6 A;  4GY2 A;  2C8G A;  2C8C A;  1GZF A;  2J3Z A;  1GIQ A;  1ZXV A;  1J7N A;  4XM7 A;  2C8F E;  3BW8 A;  4PKT A;  4H0V A;  1PWV A;  1GIR A;  1PWQ A;  1JKY A;  1OG3 A;  4XSH B;  4FML A;  2WN4 A;  2WN6 A;  4PKR A;  2C8E E;  1GZE A; 
#chains in the Genus database with same CATH homology
 1GXZ A;  1PWW A;  5H04 A;  4TR5 A;  2J3X A;  4PKQ A;  1R4B A;  1OG1 A;  3U0J A;  4H0T A;  4XSG B;  3BUZ A;  1UZI A;  2BOV B;  5D1T A;  1G24 A;  2WN7 A;  1PWU A;  2C8D A;  2C8B X;  2C8A A;  5BWM B;  4PKU A;  4ELN A;  2WN8 A;  1QS2 A;  2WN5 A;  2GWM A;  4GF1 A;  2J3V A;  4H0X A;  1QS1 A;  1OJZ A;  4XM8 A;  4FXQ A;  2C8H A;  4PKW A;  1PWP A;  4FK7 A;  1R45 A;  4PKS A;  1OG4 A;  1GXY A;  2C89 A;  5GTT A;  1GY0 A;  4H0Y A;  1OJQ A;  5H03 A;  5D1S A;  4H03 A;  2A78 B;  5D1U A;  1YQY A;  4DV8 A;  4WF6 A;  2GWL A;  5DZQ A;  4PKV A;  2A9K B;  3NTS A;  4XM6 A;  4GY2 A;  2C8G A;  2C8C A;  1GZF A;  2J3Z A;  1GIQ A;  1ZXV A;  1J7N A;  4XM7 A;  2C8F E;  3BW8 A;  4PKT A;  4H0V A;  1PWV A;  1GIR A;  1PWQ A;  1JKY A;  1OG3 A;  4XSH B;  4FML A;  2WN4 A;  2WN6 A;  4PKR A;  2C8E E;  1GZE A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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