4H0YA

Crystal structure of nad+-ia(e380s)-actin complex
Total Genus 143
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
143
sequence length
413
structure length
413
Chain Sequence
AFIERPEDFLKDKENAIQWEKKEAERVEKNLDTLEKEALELYKKDSEQISNYSQTRQYFYDYQIESNPREKEYKNLRNAISKNKIDKPINVYYFESPEKFAFNKEIRTENQNEISLEKFNELKETIQDKLFKQDGFKDVSLYEPGNGDEKPTPLLIHLKLPKNTGMLPYINSNDVKTLIEQDYSIKIDKIVRIVIEGKQYIKAEASIVNSLDFKDDVSKGDLWGKENYSDWSNKLTPNELADVNDYMRGGYTAINNYLISNGPLNNPNPELDSKVNNIENALKLTPIPSNLIVYRRSGPQEFGLTLTSPEYDFNKIENIDAFKEKWEGKVITYPNFISTSIGSVNMSAFAKRKIILRINIPKDSPGAYLSAIPGYAGEYSVLLNHGSKFKINKVDSYKDGTVTKLILDATLIN
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
{{ tooltip.sname }} connected with {{ tooltip.tname }} : {{qFormat(tooltip.svalue) }}
publication title Arginine ADP-ribosylation mechanism based on structural snapshots of iota-toxin and actin complex
pubmed doi rcsb
molecule tags Toxin/structural protein
source organism Clostridium perfringens
molecule keywords Iota toxin component Ia
total genus 143
structure length 413
sequence length 413
ec nomenclature ec 2.4.2.31: NAD(+)--protein-arginine ADP-ribosyltransferase.
pdb deposition date 2012-09-10

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF03496 ADPrib_exo_Tox ADP-ribosyltransferase exoenzyme
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.176.10 Alpha Beta Alpha-Beta Complex Toxin ADP-ribosyltransferase; Chain A, domain 1 Toxin ADP-ribosyltransferase; Chain A, domain 1 4h0yA02
3.90.176.10 Alpha Beta Alpha-Beta Complex Toxin ADP-ribosyltransferase; Chain A, domain 1 Toxin ADP-ribosyltransferase; Chain A, domain 1 4h0yA01
2A78B 3BUZA 1YQYA 1R45A 5H04A 2WN5A 4PKSA 4PKTA 2C8BX 4H0XA 2BOVB 1J7NA 2C89A 1QS2A 1PWVA 1OG3A 5BWMB 4H03A 3NTSA 1QS1A 4FXQA 4ELNA 4GF1A 4PKQA 4PKVA 4DV8A 1ZXVA 4H0VA 2C8EE 2WN8A 2C8DA 5DZQA 5H03A 2WN7A 4PKUA 2A9KB 4H0YA 2J3ZA 1PWPA 1PWQA 2C8GA 1GZFA 2WN4A 1GZEA 1GXYA 1R4BA 1OJZA 2J3XA 4XM8A 4GY2A 1OG1A 5D1SA 4WF6A 4FMLA 1JKYA 4PKWA 1G24A 2J3VA 1UZIA 5D1UA 3U0JA 4XM7A 3BW8A 2C8FE 2GWLA 4XSGB 1PWWA 1GIQA 1OJQA 2C8CA 4FK7A 1PWUA 5GTTA 1GXZA 2C8HA 4XSHB 2WN6A 1OG4A 1GIRA 2C8AA 4TR5A 1GY0A 4PKRA 2GWMA 4XM6A 5D1TA 4H0TA
chains in the Genus database with same CATH superfamily
2A78B 3BUZA 1YQYA 1R45A 5H04A 2WN5A 4PKSA 4PKTA 2C8BX 4H0XA 2BOVB 1J7NA 2C89A 1QS2A 1PWVA 1OG3A 5BWMB 4H03A 3NTSA 1QS1A 4FXQA 4ELNA 4GF1A 4PKQA 4PKVA 4DV8A 1ZXVA 4H0VA 2C8EE 2WN8A 2C8DA 5DZQA 5H03A 2WN7A 4PKUA 2A9KB 4H0YA 2J3ZA 1PWPA 1PWQA 2C8GA 1GZFA 2WN4A 1GZEA 1GXYA 1R4BA 1OJZA 2J3XA 4XM8A 4GY2A 1OG1A 5D1SA 4WF6A 4FMLA 1JKYA 4PKWA 1G24A 2J3VA 1UZIA 5D1UA 3U0JA 4XM7A 3BW8A 2C8FE 2GWLA 4XSGB 1PWWA 1GIQA 1OJQA 2C8CA 4FK7A 1PWUA 5GTTA 1GXZA 2C8HA 4XSHB 2WN6A 1OG4A 1GIRA 2C8AA 4TR5A 1GY0A 4PKRA 2GWMA 4XM6A 5D1TA 4H0TA
chains in the Genus database with same CATH topology
2A78B 3BUZA 1YQYA 1R45A 5H04A 2WN5A 4PKSA 4PKTA 2C8BX 4H0XA 2BOVB 1J7NA 2C89A 1QS2A 1PWVA 1OG3A 5BWMB 4H03A 3NTSA 1QS1A 4FXQA 4ELNA 4GF1A 4PKQA 4PKVA 4DV8A 1ZXVA 4H0VA 2C8EE 2WN8A 2C8DA 5DZQA 5H03A 2WN7A 4PKUA 2A9KB 4H0YA 2J3ZA 1PWPA 1PWQA 2C8GA 1GZFA 2WN4A 1GZEA 1GXYA 1R4BA 1OJZA 2J3XA 4XM8A 4GY2A 1OG1A 5D1SA 4WF6A 4FMLA 1JKYA 4PKWA 1G24A 2J3VA 1UZIA 5D1UA 3U0JA 4XM7A 3BW8A 2C8FE 2GWLA 4XSGB 1PWWA 1GIQA 1OJQA 2C8CA 4FK7A 1PWUA 5GTTA 1GXZA 2C8HA 4XSHB 2WN6A 1OG4A 1GIRA 2C8AA 4TR5A 1GY0A 4PKRA 2GWMA 4XM6A 5D1TA 4H0TA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2A78 B;  3BUZ A;  1YQY A;  1R45 A;  5H04 A;  2WN5 A;  4PKS A;  4PKT A;  2C8B X;  4H0X A;  2BOV B;  1J7N A;  2C89 A;  1QS2 A;  1PWV A;  1OG3 A;  5BWM B;  4H03 A;  3NTS A;  1QS1 A;  4FXQ A;  4ELN A;  4GF1 A;  4PKQ A;  4PKV A;  4DV8 A;  1ZXV A;  4H0V A;  2C8E E;  2WN8 A;  2C8D A;  5DZQ A;  5H03 A;  2WN7 A;  4PKU A;  2A9K B;  4H0Y A;  2J3Z A;  1PWP A;  1PWQ A;  2C8G A;  1GZF A;  2WN4 A;  1GZE A;  1GXY A;  1R4B A;  1OJZ A;  2J3X A;  4XM8 A;  4GY2 A;  1OG1 A;  5D1S A;  4WF6 A;  4FML A;  1JKY A;  4PKW A;  1G24 A;  2J3V A;  1UZI A;  5D1U A;  3U0J A;  4XM7 A;  3BW8 A;  2C8F E;  2GWL A;  4XSG B;  1PWW A;  1GIQ A;  1OJQ A;  2C8C A;  4FK7 A;  1PWU A;  5GTT A;  1GXZ A;  2C8H A;  4XSH B;  2WN6 A;  1OG4 A;  1GIR A;  2C8A A;  4TR5 A;  1GY0 A;  4PKR A;  2GWM A;  4XM6 A;  5D1T A;  4H0T A; 
#chains in the Genus database with same CATH topology
 2A78 B;  3BUZ A;  1YQY A;  1R45 A;  5H04 A;  2WN5 A;  4PKS A;  4PKT A;  2C8B X;  4H0X A;  2BOV B;  1J7N A;  2C89 A;  1QS2 A;  1PWV A;  1OG3 A;  5BWM B;  4H03 A;  3NTS A;  1QS1 A;  4FXQ A;  4ELN A;  4GF1 A;  4PKQ A;  4PKV A;  4DV8 A;  1ZXV A;  4H0V A;  2C8E E;  2WN8 A;  2C8D A;  5DZQ A;  5H03 A;  2WN7 A;  4PKU A;  2A9K B;  4H0Y A;  2J3Z A;  1PWP A;  1PWQ A;  2C8G A;  1GZF A;  2WN4 A;  1GZE A;  1GXY A;  1R4B A;  1OJZ A;  2J3X A;  4XM8 A;  4GY2 A;  1OG1 A;  5D1S A;  4WF6 A;  4FML A;  1JKY A;  4PKW A;  1G24 A;  2J3V A;  1UZI A;  5D1U A;  3U0J A;  4XM7 A;  3BW8 A;  2C8F E;  2GWL A;  4XSG B;  1PWW A;  1GIQ A;  1OJQ A;  2C8C A;  4FK7 A;  1PWU A;  5GTT A;  1GXZ A;  2C8H A;  4XSH B;  2WN6 A;  1OG4 A;  1GIR A;  2C8A A;  4TR5 A;  1GY0 A;  4PKR A;  2GWM A;  4XM6 A;  5D1T A;  4H0T A; 
#chains in the Genus database with same CATH homology
 2A78 B;  3BUZ A;  1YQY A;  1R45 A;  5H04 A;  2WN5 A;  4PKS A;  4PKT A;  2C8B X;  4H0X A;  2BOV B;  1J7N A;  2C89 A;  1QS2 A;  1PWV A;  1OG3 A;  5BWM B;  4H03 A;  3NTS A;  1QS1 A;  4FXQ A;  4ELN A;  4GF1 A;  4PKQ A;  4PKV A;  4DV8 A;  1ZXV A;  4H0V A;  2C8E E;  2WN8 A;  2C8D A;  5DZQ A;  5H03 A;  2WN7 A;  4PKU A;  2A9K B;  4H0Y A;  2J3Z A;  1PWP A;  1PWQ A;  2C8G A;  1GZF A;  2WN4 A;  1GZE A;  1GXY A;  1R4B A;  1OJZ A;  2J3X A;  4XM8 A;  4GY2 A;  1OG1 A;  5D1S A;  4WF6 A;  4FML A;  1JKY A;  4PKW A;  1G24 A;  2J3V A;  1UZI A;  5D1U A;  3U0J A;  4XM7 A;  3BW8 A;  2C8F E;  2GWL A;  4XSG B;  1PWW A;  1GIQ A;  1OJQ A;  2C8C A;  4FK7 A;  1PWU A;  5GTT A;  1GXZ A;  2C8H A;  4XSH B;  2WN6 A;  1OG4 A;  1GIR A;  2C8A A;  4TR5 A;  1GY0 A;  4PKR A;  2GWM A;  4XM6 A;  5D1T A;  4H0T A; 
...loading similar chains, please wait...
similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
#similar chains, but unknotted
...loading similar chains, please wait...
#similar chains in the pdb database (?% sequence similarity)
...loading similar chains, please wait...