4H0YA

Crystal structure of nad+-ia(e380s)-actin complex
Total Genus 143
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
143
sequence length
413
structure length
413
Chain Sequence
AFIERPEDFLKDKENAIQWEKKEAERVEKNLDTLEKEALELYKKDSEQISNYSQTRQYFYDYQIESNPREKEYKNLRNAISKNKIDKPINVYYFESPEKFAFNKEIRTENQNEISLEKFNELKETIQDKLFKQDGFKDVSLYEPGNGDEKPTPLLIHLKLPKNTGMLPYINSNDVKTLIEQDYSIKIDKIVRIVIEGKQYIKAEASIVNSLDFKDDVSKGDLWGKENYSDWSNKLTPNELADVNDYMRGGYTAINNYLISNGPLNNPNPELDSKVNNIENALKLTPIPSNLIVYRRSGPQEFGLTLTSPEYDFNKIENIDAFKEKWEGKVITYPNFISTSIGSVNMSAFAKRKIILRINIPKDSPGAYLSAIPGYAGEYSVLLNHGSKFKINKVDSYKDGTVTKLILDATLIN
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Arginine ADP-ribosylation mechanism based on structural snapshots of iota-toxin and actin complex
pubmed doi rcsb
molecule tags Toxin/structural protein
source organism Clostridium perfringens
molecule keywords Iota toxin component Ia
total genus 143
structure length 413
sequence length 413
ec nomenclature ec 2.4.2.31: NAD(+)--protein-arginine ADP-ribosyltransferase.
pdb deposition date 2012-09-10

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF03496 ADPrib_exo_Tox ADP-ribosyltransferase exoenzyme
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.176.10 Alpha Beta Alpha-Beta Complex Toxin ADP-ribosyltransferase; Chain A, domain 1 Toxin ADP-ribosyltransferase; Chain A, domain 1 4h0yA02
3.90.176.10 Alpha Beta Alpha-Beta Complex Toxin ADP-ribosyltransferase; Chain A, domain 1 Toxin ADP-ribosyltransferase; Chain A, domain 1 4h0yA01
1PWPA 4XM7A 1R45A 5DZQA 2C89A 4PKTA 2WN5A 1PWWA 1GZFA 4WF6A 1OJQA 1GIQA 1GIRA 4H03A 2C8AA 1PWUA 2C8BX 2GWMA 3U0JA 1J7NA 3BUZA 4XM8A 4XSHB 1GXYA 2J3XA 3BW8A 4PKWA 4GY2A 1PWQA 4GF1A 2C8GA 5GTTA 4XM6A 2BOVB 4PKSA 5BWMB 2C8HA 4PKQA 1GY0A 1OG3A 2WN7A 4H0YA 4TR5A 1QS2A 2A9KB 5H03A 4FMLA 4FXQA 2C8DA 4H0TA 4FK7A 1OG1A 3NTSA 4H0VA 1G24A 2C8EE 2J3ZA 2WN8A 1QS1A 5D1UA 5D1SA 1YQYA 5D1TA 2C8FE 4H0XA 2GWLA 2A78B 4PKVA 4ELNA 1ZXVA 1GZEA 2WN4A 2C8CA 5H04A 1OJZA 1UZIA 2WN6A 4DV8A 4PKUA 2J3VA 1JKYA 4XSGB 1OG4A 4PKRA 1R4BA 1PWVA 1GXZA
chains in the Genus database with same CATH superfamily
1PWPA 4XM7A 1R45A 5DZQA 2C89A 4PKTA 2WN5A 1PWWA 1GZFA 4WF6A 1OJQA 1GIQA 1GIRA 4H03A 2C8AA 1PWUA 2C8BX 2GWMA 3U0JA 1J7NA 3BUZA 4XM8A 4XSHB 1GXYA 2J3XA 3BW8A 4PKWA 4GY2A 1PWQA 4GF1A 2C8GA 5GTTA 4XM6A 2BOVB 4PKSA 5BWMB 2C8HA 4PKQA 1GY0A 1OG3A 2WN7A 4H0YA 4TR5A 1QS2A 2A9KB 5H03A 4FMLA 4FXQA 2C8DA 4H0TA 4FK7A 1OG1A 3NTSA 4H0VA 1G24A 2C8EE 2J3ZA 2WN8A 1QS1A 5D1UA 5D1SA 1YQYA 5D1TA 2C8FE 4H0XA 2GWLA 2A78B 4PKVA 4ELNA 1ZXVA 1GZEA 2WN4A 2C8CA 5H04A 1OJZA 1UZIA 2WN6A 4DV8A 4PKUA 2J3VA 1JKYA 4XSGB 1OG4A 4PKRA 1R4BA 1PWVA 1GXZA
chains in the Genus database with same CATH topology
1PWPA 4XM7A 1R45A 5DZQA 2C89A 4PKTA 2WN5A 1PWWA 1GZFA 4WF6A 1OJQA 1GIQA 1GIRA 4H03A 2C8AA 1PWUA 2C8BX 2GWMA 3U0JA 1J7NA 3BUZA 4XM8A 4XSHB 1GXYA 2J3XA 3BW8A 4PKWA 4GY2A 1PWQA 4GF1A 2C8GA 5GTTA 4XM6A 2BOVB 4PKSA 5BWMB 2C8HA 4PKQA 1GY0A 1OG3A 2WN7A 4H0YA 4TR5A 1QS2A 2A9KB 5H03A 4FMLA 4FXQA 2C8DA 4H0TA 4FK7A 1OG1A 3NTSA 4H0VA 1G24A 2C8EE 2J3ZA 2WN8A 1QS1A 5D1UA 5D1SA 1YQYA 5D1TA 2C8FE 4H0XA 2GWLA 2A78B 4PKVA 4ELNA 1ZXVA 1GZEA 2WN4A 2C8CA 5H04A 1OJZA 1UZIA 2WN6A 4DV8A 4PKUA 2J3VA 1JKYA 4XSGB 1OG4A 4PKRA 1R4BA 1PWVA 1GXZA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1PWP A;  4XM7 A;  1R45 A;  5DZQ A;  2C89 A;  4PKT A;  2WN5 A;  1PWW A;  1GZF A;  4WF6 A;  1OJQ A;  1GIQ A;  1GIR A;  4H03 A;  2C8A A;  1PWU A;  2C8B X;  2GWM A;  3U0J A;  1J7N A;  3BUZ A;  4XM8 A;  4XSH B;  1GXY A;  2J3X A;  3BW8 A;  4PKW A;  4GY2 A;  1PWQ A;  4GF1 A;  2C8G A;  5GTT A;  4XM6 A;  2BOV B;  4PKS A;  5BWM B;  2C8H A;  4PKQ A;  1GY0 A;  1OG3 A;  2WN7 A;  4H0Y A;  4TR5 A;  1QS2 A;  2A9K B;  5H03 A;  4FML A;  4FXQ A;  2C8D A;  4H0T A;  4FK7 A;  1OG1 A;  3NTS A;  4H0V A;  1G24 A;  2C8E E;  2J3Z A;  2WN8 A;  1QS1 A;  5D1U A;  5D1S A;  1YQY A;  5D1T A;  2C8F E;  4H0X A;  2GWL A;  2A78 B;  4PKV A;  4ELN A;  1ZXV A;  1GZE A;  2WN4 A;  2C8C A;  5H04 A;  1OJZ A;  1UZI A;  2WN6 A;  4DV8 A;  4PKU A;  2J3V A;  1JKY A;  4XSG B;  1OG4 A;  4PKR A;  1R4B A;  1PWV A;  1GXZ A; 
#chains in the Genus database with same CATH topology
 1PWP A;  4XM7 A;  1R45 A;  5DZQ A;  2C89 A;  4PKT A;  2WN5 A;  1PWW A;  1GZF A;  4WF6 A;  1OJQ A;  1GIQ A;  1GIR A;  4H03 A;  2C8A A;  1PWU A;  2C8B X;  2GWM A;  3U0J A;  1J7N A;  3BUZ A;  4XM8 A;  4XSH B;  1GXY A;  2J3X A;  3BW8 A;  4PKW A;  4GY2 A;  1PWQ A;  4GF1 A;  2C8G A;  5GTT A;  4XM6 A;  2BOV B;  4PKS A;  5BWM B;  2C8H A;  4PKQ A;  1GY0 A;  1OG3 A;  2WN7 A;  4H0Y A;  4TR5 A;  1QS2 A;  2A9K B;  5H03 A;  4FML A;  4FXQ A;  2C8D A;  4H0T A;  4FK7 A;  1OG1 A;  3NTS A;  4H0V A;  1G24 A;  2C8E E;  2J3Z A;  2WN8 A;  1QS1 A;  5D1U A;  5D1S A;  1YQY A;  5D1T A;  2C8F E;  4H0X A;  2GWL A;  2A78 B;  4PKV A;  4ELN A;  1ZXV A;  1GZE A;  2WN4 A;  2C8C A;  5H04 A;  1OJZ A;  1UZI A;  2WN6 A;  4DV8 A;  4PKU A;  2J3V A;  1JKY A;  4XSG B;  1OG4 A;  4PKR A;  1R4B A;  1PWV A;  1GXZ A; 
#chains in the Genus database with same CATH homology
 1PWP A;  4XM7 A;  1R45 A;  5DZQ A;  2C89 A;  4PKT A;  2WN5 A;  1PWW A;  1GZF A;  4WF6 A;  1OJQ A;  1GIQ A;  1GIR A;  4H03 A;  2C8A A;  1PWU A;  2C8B X;  2GWM A;  3U0J A;  1J7N A;  3BUZ A;  4XM8 A;  4XSH B;  1GXY A;  2J3X A;  3BW8 A;  4PKW A;  4GY2 A;  1PWQ A;  4GF1 A;  2C8G A;  5GTT A;  4XM6 A;  2BOV B;  4PKS A;  5BWM B;  2C8H A;  4PKQ A;  1GY0 A;  1OG3 A;  2WN7 A;  4H0Y A;  4TR5 A;  1QS2 A;  2A9K B;  5H03 A;  4FML A;  4FXQ A;  2C8D A;  4H0T A;  4FK7 A;  1OG1 A;  3NTS A;  4H0V A;  1G24 A;  2C8E E;  2J3Z A;  2WN8 A;  1QS1 A;  5D1U A;  5D1S A;  1YQY A;  5D1T A;  2C8F E;  4H0X A;  2GWL A;  2A78 B;  4PKV A;  4ELN A;  1ZXV A;  1GZE A;  2WN4 A;  2C8C A;  5H04 A;  1OJZ A;  1UZI A;  2WN6 A;  4DV8 A;  4PKU A;  2J3V A;  1JKY A;  4XSG B;  1OG4 A;  4PKR A;  1R4B A;  1PWV A;  1GXZ A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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