4Q58 | Genus

Total Genus 65

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus	65
sequence length	225
structure length	225
Chain Sequence	DERDRVQKKTFTKWVNKHLIKAQRHISDLYEDLRDGHNLISLLEVLSGDSLPREKGRMRFHKLQNVQIALDYLRHRQVKLVNIRNDDIADGNPKLTLGLIWTIILHFQISDIQVSGQSEDMTAKEKLLLWSQRMVEGYQGLRCDNFTSSWRDGRLFNAIIHRHKPLLIDMNKVYRQTNLENLDQAFSVAERDLGVTRLLDPEDVDVPQPDEKSIITYVSSLYDAM

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

loadScript /static/js/j2s/core/package.js

loadScript /static/js/j2s/core/corejmol.z.js

loadScript /static/js/j2s/core/corescript.z.js

JSmol exec jmolApplet0 start applet null

Jmol JavaScript applet jmolApplet0__14474205764640535__ initializing

Jmol getValue debug null

Jmol getValue logLevel null

Jmol getValue allowjavascript null

AppletRegistry.checkIn(jmolApplet0__14474205764640535__)

vwrOptions:

{ "name":"jmolApplet0","applet":true,"documentBase":"https://genus.fuw.edu.pl/view/4Q58/A/","platform":"J.awtjs2d.Platform","fullName":"jmolApplet0__14474205764640535__","codePath":"https:/static/js/j2s/","display":"jmolApplet0_canvas2d","signedApplet":"true","appletReadyCallback":"Jmol._readyCallback","statusListener":"[J.appletjs.Jmol object]","syncId":"14474205764640535","bgcolor":"white" }

setting document base to "https://genus.fuw.edu.pl/view/4Q58/A/"

Jmol Version: 14.29.13 2018-04-17 17:17

java.vendor: Java2Script (HTML5)

java.version: 2018-01-28 23:38:52 (JSmol/j2s)

os.name: Mozilla/5.0 AppleWebKit/537.36 (KHTML, like Gecko; compatible; ClaudeBot/1.0; +claudebot@anthropic.com)

Access: ALL

memory: 0.0/0.0

processors available: 1

useCommandThread: false

appletId:jmolApplet0 (signed)

Jmol getValue emulate null

defaults = "Jmol"

Jmol getValue boxbgcolor null

Jmol getValue bgcolor white

backgroundColor = "white"

Jmol getValue ANIMFRAMECallback null

Jmol getValue APPLETREADYCallback Jmol._readyCallback

APPLETREADYCallback = "Jmol._readyCallback"

callback set for APPLETREADYCallback Jmol._readyCallback APPLETREADY

Jmol getValue ATOMMOVEDCallback null

Jmol getValue AUDIOCallback null

Jmol getValue CLICKCallback null

Jmol getValue DRAGDROPCallback null

Jmol getValue ECHOCallback null

Jmol getValue ERRORCallback null

Jmol getValue EVALCallback null

Jmol getValue HOVERCallback null

Jmol getValue IMAGECallback null

Jmol getValue LOADSTRUCTCallback null

Jmol getValue MEASURECallback null

Jmol getValue MESSAGECallback null

Jmol getValue MINIMIZATIONCallback null

Jmol getValue SERVICECallback null

Jmol getValue PICKCallback null

Jmol getValue RESIZECallback null

Jmol getValue SCRIPTCallback null

Jmol getValue SYNCCallback null

Jmol getValue STRUCTUREMODIFIEDCallback null

Jmol getValue doTranslate null

language=en_US

Jmol getValue popupMenu null

Jmol getValue script null

Jmol getValue loadInline null

Jmol getValue load null

Jmol applet jmolApplet0__14474205764640535__ ready

script 1 started

platformSpeed = 8

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Genus data interpretation

Chord Diagram

molecule tags	Structural protein/protein binding
publication title	Crystal structure of the plectin 1a actin-binding domain/integrin beta 4 fragment complex rcsb
molecule keywords	Plectin
total genus	65
structure length	225
sequence length	225
chains with identical sequence	B
ec nomenclature
pdb deposition date	2014-04-16

pfam database annotations

chain	Pfam Accession Code	Pfam Family Identifier	Pfam Description
A	PF00307	CH	Calponin homology (CH) domain

Image from the rcsb pdb (www.rcsb.org)

cath code	Class	Architecture	Topology	Homology	Domain
1.10.418.10	Mainly Alpha	Orthogonal Bundle	Actin-binding Protein, T-fimbrin; domain 1	Calponin-like domain	4q58A02
1.10.418.10	Mainly Alpha	Orthogonal Bundle	Actin-binding Protein, T-fimbrin; domain 1	Calponin-like domain	4q58A01

4EDMA 1RT8A 1BKRA 1AOAA 2DK9A 3HOPA 1DXXA 5L0OA 3KMWB 1WYRA 3I6XA 1UEGA 1VKAA 4TXIA 2RR8A 1MB8A 1AA2A 2EYIA 3KMUB 5A37A 3JARM 1WKUA 2EYNA 1TJTA 2VZIB 4B7LA 2D88A 2D89A 5BVRA 2VZGB 2E9KA 3HORA 1BHDA 5A36A 4TXKA 4EDNA 3JAKM 2VZDA 2WFNA 2QJXA 3JALM 4Q57B 4Q58A 3FERA 1P5SA 5A4BA 1UJOA 2WA6A 3REPB 3HOCA 3KY9A 2YRNA 1QAGA 2L3GA 2JV9A 2K3SA 1WYLA 1P2XA 2QJZA 4EDLA 2VZCA 1WYPA 3CO1A 2D87A 2R8UA 3F7PA 1WYNA 1PXYA 2R0OA 1WYMA 1H67A 2D85A 1WYOA 1V5KA 1WYQA 1SH5A 4Q59A 1PA7A 2D86A 2K2RA 1WIXA 5A38A 2EE7A 2WA7A 5J8EA 1WJOA 1SH6A 2WA5A
chains in the Genus database with same CATH superfamily

4EDMA 1RT8A 1BKRA 1AOAA 2DK9A 3HOPA 1DXXA 5L0OA 3KMWB 1WYRA 2HKPA 2VE7C 2WDTA 4DDPA 3I6XA 1UEGA 1VKAA 4TXIA 2RR8A 1MB8A 1AA2A 2EYIA 3KMUB 5A37A 3JARM 1WKUA 2IGPA 2EYNA 3VP7A 1TJTA 2VZIB 4B7LA 2D88A 2D89A 5BVRA 2VZGB 2E9KA 3HORA 1BHDA 5A36A 4TXKA 4EDNA 2HL9A 3JAKM 2VZDA 2WFNA 2QJXA 3JALM 4Q57B 4Q58A 2WE6A 3FERA 4LVPA 1P5SA 5A4BA 1UJOA 2WA6A 3REPB 5FMTA 3HOCA 3KY9A 2YRNA 1QAGA 2L3GA 2JV9A 2K3SA 1WYLA 2EQOA 1P2XA 2QJZA 4LVRA 4EDLA 2VZCA 1WYPA 1EUVA 3CO1A 2D87A 2R8UA 3F7PA 1WYNA 1PXYA 2R0OA 1WYMA 1H67A 2D85A 2HL8A 1WYOA 2VE7A 1V5KA 1WYQA 1SH5A 4Q59A 1PA7A 2D86A 2K2RA 1WIXA 5A38A 5FMUA 2EE7A 3EAYA 2WA7A 5J8EA 1WJOA 1SH6A 2WA5A
chains in the Genus database with same CATH topology

#chains in the Genus database with same CATH superfamily
 4EDM A;  1RT8 A;  1BKR A;  1AOA A;  2DK9 A;  3HOP A;  1DXX A;  5L0O A;  3KMW B;  1WYR A;  3I6X A;  1UEG A;  1VKA A;  4TXI A;  2RR8 A;  1MB8 A;  1AA2 A;  2EYI A;  3KMU B;  5A37 A;  3JAR M;  1WKU A;  2EYN A;  1TJT A;  2VZI B;  4B7L A;  2D88 A;  2D89 A;  5BVR A;  2VZG B;  2E9K A;  3HOR A;  1BHD A;  5A36 A;  4TXK A;  4EDN A;  3JAK M;  2VZD A;  2WFN A;  2QJX A;  3JAL M;  4Q57 B;  4Q58 A;  3FER A;  1P5S A;  5A4B A;  1UJO A;  2WA6 A;  3REP B;  3HOC A;  3KY9 A;  2YRN A;  1QAG A;  2L3G A;  2JV9 A;  2K3S A;  1WYL A;  1P2X A;  2QJZ A;  4EDL A;  2VZC A;  1WYP A;  3CO1 A;  2D87 A;  2R8U A;  3F7P A;  1WYN A;  1PXY A;  2R0O A;  1WYM A;  1H67 A;  2D85 A;  1WYO A;  1V5K A;  1WYQ A;  1SH5 A;  4Q59 A;  1PA7 A;  2D86 A;  2K2R A;  1WIX A;  5A38 A;  2EE7 A;  2WA7 A;  5J8E A;  1WJO A;  1SH6 A;  2WA5 A; 
#chains in the Genus database with same CATH topology
 4EDM A;  1RT8 A;  1BKR A;  1AOA A;  2DK9 A;  3HOP A;  1DXX A;  5L0O A;  3KMW B;  1WYR A;  2HKP A;  2VE7 C;  2WDT A;  4DDP A;  3I6X A;  1UEG A;  1VKA A;  4TXI A;  2RR8 A;  1MB8 A;  1AA2 A;  2EYI A;  3KMU B;  5A37 A;  3JAR M;  1WKU A;  2IGP A;  2EYN A;  3VP7 A;  1TJT A;  2VZI B;  4B7L A;  2D88 A;  2D89 A;  5BVR A;  2VZG B;  2E9K A;  3HOR A;  1BHD A;  5A36 A;  4TXK A;  4EDN A;  2HL9 A;  3JAK M;  2VZD A;  2WFN A;  2QJX A;  3JAL M;  4Q57 B;  4Q58 A;  2WE6 A;  3FER A;  4LVP A;  1P5S A;  5A4B A;  1UJO A;  2WA6 A;  3REP B;  5FMT A;  3HOC A;  3KY9 A;  2YRN A;  1QAG A;  2L3G A;  2JV9 A;  2K3S A;  1WYL A;  2EQO A;  1P2X A;  2QJZ A;  4LVR A;  4EDL A;  2VZC A;  1WYP A;  1EUV A;  3CO1 A;  2D87 A;  2R8U A;  3F7P A;  1WYN A;  1PXY A;  2R0O A;  1WYM A;  1H67 A;  2D85 A;  2HL8 A;  1WYO A;  2VE7 A;  1V5K A;  1WYQ A;  1SH5 A;  4Q59 A;  1PA7 A;  2D86 A;  2K2R A;  1WIX A;  5A38 A;  5FMU A;  2EE7 A;  3EAY A;  2WA7 A;  5J8E A;  1WJO A;  1SH6 A;  2WA5 A; 
#chains in the Genus database with same CATH homology
 4EDM A;  1RT8 A;  1BKR A;  1AOA A;  2DK9 A;  3HOP A;  1DXX A;  5L0O A;  3KMW B;  1WYR A;  3I6X A;  1UEG A;  1VKA A;  4TXI A;  2RR8 A;  1MB8 A;  1AA2 A;  2EYI A;  3KMU B;  5A37 A;  3JAR M;  1WKU A;  2EYN A;  1TJT A;  2VZI B;  4B7L A;  2D88 A;  2D89 A;  5BVR A;  2VZG B;  2E9K A;  3HOR A;  1BHD A;  5A36 A;  4TXK A;  4EDN A;  3JAK M;  2VZD A;  2WFN A;  2QJX A;  3JAL M;  4Q57 B;  4Q58 A;  3FER A;  1P5S A;  5A4B A;  1UJO A;  2WA6 A;  3REP B;  3HOC A;  3KY9 A;  2YRN A;  1QAG A;  2L3G A;  2JV9 A;  2K3S A;  1WYL A;  1P2X A;  2QJZ A;  4EDL A;  2VZC A;  1WYP A;  3CO1 A;  2D87 A;  2R8U A;  3F7P A;  1WYN A;  1PXY A;  2R0O A;  1WYM A;  1H67 A;  2D85 A;  1WYO A;  1V5K A;  1WYQ A;  1SH5 A;  4Q59 A;  1PA7 A;  2D86 A;  2K2R A;  1WIX A;  5A38 A;  2EE7 A;  2WA7 A;  5J8E A;  1WJO A;  1SH6 A;  2WA5 A;

...loading similar chains, please wait...
similar chains in the Genus database (?% sequence similarity)

...loading similar chains, please wait...
similar chains in the pdb database (?% sequence similarity)

#similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
#similar chains, but unknotted
...loading similar chains, please wait...
#similar chains in the pdb database (?% sequence similarity)
...loading similar chains, please wait...

4Q58A

Total Genus

sequence length

structure length

Chain Sequence

Structure visualization

Chord Diagram

connected with : NaN

pfam database annotations