5L0OA

Iqgap1 calponin homology domain fragment (chdf) mutant k161c under oxidizing conditions
Total Genus 60
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
60
sequence length
164
structure length
164
Chain Sequence
AEEMDERRRQNVAYEYLCHLEEAKRWMEACLGEDLPPTTELEEGLRNGVYLAKLGNFFSPKVVSLKKIYDREQTRYKATGLHFRHTDNVIQWLNAMDEIGLPKIFYPETTDIYDRKNMPRCIYCIHALSLYLFCLGLAPQIQDLYGKVDFTEEEINNMKTELEK
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title The IQGAP1 N-Terminus Forms Dimers, and the Dimer Interface Is Required for Binding F-Actin and Calcium-Bound Calmodulin.
pubmed doi rcsb
molecule tags Signaling protein
source organism Homo sapiens
molecule keywords Ras GTPase-activating-like protein IQGAP1
total genus 60
structure length 164
sequence length 164
chains with identical sequence B, C, D
ec nomenclature
pdb deposition date 2016-07-27

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00307 CH Calponin homology (CH) domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
1.10.418.10 Mainly Alpha Orthogonal Bundle Actin-binding Protein, T-fimbrin; domain 1 Calponin-like domain 5l0oA00
5J8EA 1MB8A 1WYNA 3JALM 2D89A 2D86A 1WYQA 1V5KA 2WA6A 1PXYA 2EE7A 3KMWB 4Q59A 2RR8A 5L0OA 2K3SA 2WA7A 1WYMA 5A37A 1BHDA 1WYPA 2WFNA 2YRNA 4Q57B 3CO1A 3FERA 3HOPA 1AA2A 2VZIB 4B7LA 2DK9A 4Q58A 2E9KA 5BVRA 2VZGB 2D87A 1UJOA 2K2RA 1WIXA 5A36A 2D85A 4EDMA 3HORA 2EYNA 3REPB 5A4BA 1WKUA 5A38A 2R8UA 2VZDA 1VKAA 1WYOA 3KY9A 2QJXA 4EDNA 2VZCA 3JARM 3JAKM 1PA7A 3I6XA 1AOAA 4TXIA 2R0OA 1P5SA 1WJOA 3HOCA 1WYRA 1DXXA 1SH5A 3KMUB 1WYLA 2EYIA 1SH6A 1TJTA 4TXKA 1RT8A 2D88A 1BKRA 2L3GA 2QJZA 1QAGA 4EDLA 1UEGA 1H67A 1P2XA 2JV9A 3F7PA 2WA5A
chains in the Genus database with same CATH superfamily
5J8EA 1MB8A 1WYNA 3JALM 5FMTA 2WE6A 2D89A 2D86A 1WYQA 1V5KA 2WA6A 1PXYA 2EE7A 3KMWB 4Q59A 2RR8A 5L0OA 2K3SA 2WA7A 1WYMA 5A37A 1BHDA 1WYPA 2WFNA 2YRNA 4Q57B 3CO1A 3FERA 3HOPA 4DDPA 1AA2A 2VZIB 4B7LA 2DK9A 3VP7A 4Q58A 2E9KA 5BVRA 2VZGB 2EQOA 2D87A 1UJOA 2K2RA 1WIXA 5A36A 2D85A 4EDMA 3HORA 2EYNA 3REPB 2VE7A 5A4BA 1WKUA 5A38A 2R8UA 2WDTA 2VZDA 1VKAA 2IGPA 4LVPA 1WYOA 3KY9A 2QJXA 2VE7C 2HL8A 4EDNA 2HKPA 2VZCA 3JARM 3JAKM 4LVRA 1PA7A 3I6XA 1AOAA 4TXIA 2R0OA 1P5SA 1WJOA 3HOCA 1WYRA 1DXXA 1SH5A 3KMUB 1WYLA 2EYIA 1SH6A 1TJTA 4TXKA 1RT8A 2D88A 1BKRA 2L3GA 2QJZA 1QAGA 2HL9A 4EDLA 1UEGA 1H67A 1P2XA 2JV9A 3EAYA 3F7PA 5FMUA 2WA5A 1EUVA
chains in the Genus database with same CATH topology
5J8EA 1MB8A 1WYNA 3JALM 2D89A 2D86A 1WYQA 1V5KA 2WA6A 1PXYA 2EE7A 3KMWB 4Q59A 2RR8A 5L0OA 2K3SA 2WA7A 1WYMA 5A37A 1BHDA 1WYPA 2WFNA 2YRNA 4Q57B 3CO1A 3FERA 3HOPA 1AA2A 2VZIB 4B7LA 2DK9A 4Q58A 2E9KA 5BVRA 2VZGB 2D87A 1UJOA 2K2RA 1WIXA 5A36A 2D85A 4EDMA 3HORA 2EYNA 3REPB 5A4BA 1WKUA 5A38A 2R8UA 2VZDA 1VKAA 1WYOA 3KY9A 2QJXA 4EDNA 2VZCA 3JARM 3JAKM 1PA7A 3I6XA 1AOAA 4TXIA 2R0OA 1P5SA 1WJOA 3HOCA 1WYRA 1DXXA 1SH5A 3KMUB 1WYLA 2EYIA 1SH6A 1TJTA 4TXKA 1RT8A 2D88A 1BKRA 2L3GA 2QJZA 1QAGA 4EDLA 1UEGA 1H67A 1P2XA 2JV9A 3F7PA 2WA5A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 5J8E A;  1MB8 A;  1WYN A;  3JAL M;  2D89 A;  2D86 A;  1WYQ A;  1V5K A;  2WA6 A;  1PXY A;  2EE7 A;  3KMW B;  4Q59 A;  2RR8 A;  5L0O A;  2K3S A;  2WA7 A;  1WYM A;  5A37 A;  1BHD A;  1WYP A;  2WFN A;  2YRN A;  4Q57 B;  3CO1 A;  3FER A;  3HOP A;  1AA2 A;  2VZI B;  4B7L A;  2DK9 A;  4Q58 A;  2E9K A;  5BVR A;  2VZG B;  2D87 A;  1UJO A;  2K2R A;  1WIX A;  5A36 A;  2D85 A;  4EDM A;  3HOR A;  2EYN A;  3REP B;  5A4B A;  1WKU A;  5A38 A;  2R8U A;  2VZD A;  1VKA A;  1WYO A;  3KY9 A;  2QJX A;  4EDN A;  2VZC A;  3JAR M;  3JAK M;  1PA7 A;  3I6X A;  1AOA A;  4TXI A;  2R0O A;  1P5S A;  1WJO A;  3HOC A;  1WYR A;  1DXX A;  1SH5 A;  3KMU B;  1WYL A;  2EYI A;  1SH6 A;  1TJT A;  4TXK A;  1RT8 A;  2D88 A;  1BKR A;  2L3G A;  2QJZ A;  1QAG A;  4EDL A;  1UEG A;  1H67 A;  1P2X A;  2JV9 A;  3F7P A;  2WA5 A; 
#chains in the Genus database with same CATH topology
 5J8E A;  1MB8 A;  1WYN A;  3JAL M;  5FMT A;  2WE6 A;  2D89 A;  2D86 A;  1WYQ A;  1V5K A;  2WA6 A;  1PXY A;  2EE7 A;  3KMW B;  4Q59 A;  2RR8 A;  5L0O A;  2K3S A;  2WA7 A;  1WYM A;  5A37 A;  1BHD A;  1WYP A;  2WFN A;  2YRN A;  4Q57 B;  3CO1 A;  3FER A;  3HOP A;  4DDP A;  1AA2 A;  2VZI B;  4B7L A;  2DK9 A;  3VP7 A;  4Q58 A;  2E9K A;  5BVR A;  2VZG B;  2EQO A;  2D87 A;  1UJO A;  2K2R A;  1WIX A;  5A36 A;  2D85 A;  4EDM A;  3HOR A;  2EYN A;  3REP B;  2VE7 A;  5A4B A;  1WKU A;  5A38 A;  2R8U A;  2WDT A;  2VZD A;  1VKA A;  2IGP A;  4LVP A;  1WYO A;  3KY9 A;  2QJX A;  2VE7 C;  2HL8 A;  4EDN A;  2HKP A;  2VZC A;  3JAR M;  3JAK M;  4LVR A;  1PA7 A;  3I6X A;  1AOA A;  4TXI A;  2R0O A;  1P5S A;  1WJO A;  3HOC A;  1WYR A;  1DXX A;  1SH5 A;  3KMU B;  1WYL A;  2EYI A;  1SH6 A;  1TJT A;  4TXK A;  1RT8 A;  2D88 A;  1BKR A;  2L3G A;  2QJZ A;  1QAG A;  2HL9 A;  4EDL A;  1UEG A;  1H67 A;  1P2X A;  2JV9 A;  3EAY A;  3F7P A;  5FMU A;  2WA5 A;  1EUV A; 
#chains in the Genus database with same CATH homology
 5J8E A;  1MB8 A;  1WYN A;  3JAL M;  2D89 A;  2D86 A;  1WYQ A;  1V5K A;  2WA6 A;  1PXY A;  2EE7 A;  3KMW B;  4Q59 A;  2RR8 A;  5L0O A;  2K3S A;  2WA7 A;  1WYM A;  5A37 A;  1BHD A;  1WYP A;  2WFN A;  2YRN A;  4Q57 B;  3CO1 A;  3FER A;  3HOP A;  1AA2 A;  2VZI B;  4B7L A;  2DK9 A;  4Q58 A;  2E9K A;  5BVR A;  2VZG B;  2D87 A;  1UJO A;  2K2R A;  1WIX A;  5A36 A;  2D85 A;  4EDM A;  3HOR A;  2EYN A;  3REP B;  5A4B A;  1WKU A;  5A38 A;  2R8U A;  2VZD A;  1VKA A;  1WYO A;  3KY9 A;  2QJX A;  4EDN A;  2VZC A;  3JAR M;  3JAK M;  1PA7 A;  3I6X A;  1AOA A;  4TXI A;  2R0O A;  1P5S A;  1WJO A;  3HOC A;  1WYR A;  1DXX A;  1SH5 A;  3KMU B;  1WYL A;  2EYI A;  1SH6 A;  1TJT A;  4TXK A;  1RT8 A;  2D88 A;  1BKR A;  2L3G A;  2QJZ A;  1QAG A;  4EDL A;  1UEG A;  1H67 A;  1P2X A;  2JV9 A;  3F7P A;  2WA5 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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