1G6GA

X-ray structure of the n-terminal fha domain from s. cerevisiae rad53p in complex with a phosphothreonine peptide at 1.6 a resolution
Total Genus 34
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
34
sequence length
127
structure length
127
Chain Sequence
GENIVCRVICTTGQIPIRDLSADISQVLKEKRSIKKVWTFGRNPACDYHLGNISRLSNKHFQILLGEDGNLLLNDISTNGTWLNGQKVEKNSNQLLSQGDEITVGVGVESDILSLVIFINDKFKQCL
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title The molecular basis of FHA domain:phosphopeptide binding specificity and implications for phospho-dependent signaling mechanisms.
pubmed doi rcsb
molecule tags Cell cycle
source organism Saccharomyces cerevisiae
molecule keywords PROTEIN KINASE RAD53
total genus 34
structure length 127
sequence length 127
chains with identical sequence B
ec nomenclature ec 2.7.12.1: Dual-specificity kinase.
pdb deposition date 2000-11-06

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00498 FHA FHA domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.60.200.20 Mainly Beta Sandwich Tumour Suppressor Smad4 Tumour Suppressor Smad4 1g6gA00
2W3OA 2XT9B 1FHQA 2A0TA 2KB4A 3UNNA 4A0EA 3POAA 3I0NA 2JQIA 1K3NA 1G6GA 2LC1A 1J4PA 4EGXA 1UJXA 3VA4A 3ELVA 1YJMA 1K3JA 1J4LA 2JQJA 2BRFA 3HUEA 1YJ5C 4D9VA 1GXCA 1FHRA 5E50A 2EH0A 3VPYA 3UMZA 1J4OA 3I6UA 3UN0A 1WV3A 4H87A 1WLNA 1K2MA 2KB3A 3FM8A 1LGQA 2FEZA 2FF4A 2KFUA 1K3QA 1J4QA 5DJOA 1MZKA 2PIEA 2G1LA 4QCJA 1K2NA 3VA1A 3PO8A 4JONA 3UOTA 2CSWA 3HUFA 3HX1A 3ELSA 4G2SA 2JPEA 1R21A 3I6WA 2KKLA 3I0MA 1LGPA 1G3GA 3GQSA 3UV0A 3KT9A 3OUNA 1DMZA 2AFFA 3UNMA 2JQLA 5A8IA 1QU5A 1UHTA 4EJQA 1J4KA 2JKDA 3MDBA
chains in the Genus database with same CATH superfamily
3PFNA 2W3OA 3V80A 2XT9B 3V8RA 4L02A 1FHQA 5EJIA 3DSHA 2A0TA 2KB4A 3UNNA 1U0RA 2Q5FA 4A0EA 5JELA 3POAA 3I0NA 1Y3IA 5DHUA 1U7VB 1KHXA 2JQIA 1K3NA 1G6GA 4KU0D 2LC1A 1J4PA 4EGXA 1Y3HA 1UJXA 5JEKA 1YT5A 3VA4A 5JEMA 2P1RA 3ELVA 3DITA 4DY6A 1YJMA 3V7YA 1K3JA 1J4LA 1DEVA 2I2FA 2JQJA 3S40A 1QWTA 2QVLA 2BRFA 3HUEA 1MR1A 3VZDA 5EJFA 1ZOQA 5BVIA 5DHPA 1YJ5C 4D9VA 1GXCA 5C4VA 1FHRA 2I2AA 5E50A 2AN1A 2EH0A 3VPYA 3AFOA 3UMZA 1J4OA 3I6UA 3UN0A 2I2BA 3V8QA 2I29A 3V7WA 5DHRA 1WV3A 1YGSA 4WERA 3VZCA 4H87A 1WLNA 1K2MA 2I2CA 2KB3A 3FM8A 1LGQA 2FEZA 2FF4A 2KFUA 1K3QA 4R9PA 1J4QA 1U7VA 5DJOA 1MZKA 1U7FB 4HAOA 5JEOA 2I1WA 1Z0SA 2PIEA 2G1LA 4QCJA 5DHQA 1DD1A 1K2NA 1KHUA 3V7UA 3T5PA 3VA1A 4A4YA 3PO8A 1G88A 1Z0ZA 4JIWD 4JONA 1SUWA 3UOTA 3GMJA 2CSWA 3HUFA 3HX1A 3ELSA 2I2DA 3VZBA 4G2SA 4WRRA 2JPEA 1R21A 3V8MA 5EJGA 3I6WA 2KKLA 3I0MA 1J2FA 3A77A 5JERA 2QV7A 1LGPA 5DHTA 3GQSA 1G3GA 2BONA 5JEJA 1MJSA 2JGRA 3UV0A 3KT9A 3V8PA 3OUNA 2AFFA 1DMZA 1MK2A 3UNMA 2JQLA 3V8NA 5A8IA 5DHSA 1QU5A 4JIVD 5EJHA 1Z0UA 1U0TA 1U7FA 1UHTA 4V24A 4EJQA 1J4KA 2XXSA 2JKDA 3MDBA
chains in the Genus database with same CATH topology
2W3OA 2XT9B 4L02A 1FHQA 3DSHA 2A0TA 2KB4A 3UNNA 4A0EA 5JELA 3POAA 3I0NA 1U7VB 1KHXA 2JQIA 1K3NA 1G6GA 4KU0D 2LC1A 1J4PA 4EGXA 1UJXA 5JEKA 5JEMA 3VA4A 2P1RA 3ELVA 3DITA 1YJMA 1K3JA 1J4LA 1DEVA 2JQJA 3S40A 1QWTA 2QVLA 2BRFA 3HUEA 1MR1A 3VZDA 1ZOQA 5BVIA 1YJ5C 4D9VA 1GXCA 5C4VA 1FHRA 5E50A 2EH0A 3VPYA 3UMZA 1J4OA 3I6UA 3UN0A 1WV3A 1YGSA 4WERA 3VZCA 4H87A 1WLNA 1K2MA 2KB3A 3FM8A 1LGQA 2FEZA 2FF4A 2KFUA 1K3QA 4R9PA 1J4QA 1U7VA 5DJOA 1MZKA 1U7FB 5JEOA 2PIEA 2G1LA 4QCJA 1DD1A 1K2NA 1KHUA 3T5PA 3VA1A 4A4YA 3PO8A 1G88A 4JIWD 4JONA 3UOTA 3GMJA 2CSWA 3HUFA 3HX1A 3ELSA 3VZBA 4G2SA 4WRRA 2JPEA 1R21A 3I6WA 2KKLA 3I0MA 1J2FA 3A77A 5JERA 2QV7A 1LGPA 1G3GA 3GQSA 2BONA 5JEJA 1MJSA 2JGRA 3UV0A 3KT9A 3OUNA 2AFFA 1DMZA 1MK2A 3UNMA 2JQLA 5A8IA 1QU5A 4JIVD 1U7FA 1UHTA 4V24A 4EJQA 1J4KA 2XXSA 2JKDA 3MDBA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2W3O A;  2XT9 B;  1FHQ A;  2A0T A;  2KB4 A;  3UNN A;  4A0E A;  3POA A;  3I0N A;  2JQI A;  1K3N A;  1G6G A;  2LC1 A;  1J4P A;  4EGX A;  1UJX A;  3VA4 A;  3ELV A;  1YJM A;  1K3J A;  1J4L A;  2JQJ A;  2BRF A;  3HUE A;  1YJ5 C;  4D9V A;  1GXC A;  1FHR A;  5E50 A;  2EH0 A;  3VPY A;  3UMZ A;  1J4O A;  3I6U A;  3UN0 A;  1WV3 A;  4H87 A;  1WLN A;  1K2M A;  2KB3 A;  3FM8 A;  1LGQ A;  2FEZ A;  2FF4 A;  2KFU A;  1K3Q A;  1J4Q A;  5DJO A;  1MZK A;  2PIE A;  2G1L A;  4QCJ A;  1K2N A;  3VA1 A;  3PO8 A;  4JON A;  3UOT A;  2CSW A;  3HUF A;  3HX1 A;  3ELS A;  4G2S A;  2JPE A;  1R21 A;  3I6W A;  2KKL A;  3I0M A;  1LGP A;  1G3G A;  3GQS A;  3UV0 A;  3KT9 A;  3OUN A;  1DMZ A;  2AFF A;  3UNM A;  2JQL A;  5A8I A;  1QU5 A;  1UHT A;  4EJQ A;  1J4K A;  2JKD A;  3MDB A; 
#chains in the Genus database with same CATH topology
 3PFN A;  2W3O A;  3V80 A;  2XT9 B;  3V8R A;  4L02 A;  1FHQ A;  5EJI A;  3DSH A;  2A0T A;  2KB4 A;  3UNN A;  1U0R A;  2Q5F A;  4A0E A;  5JEL A;  3POA A;  3I0N A;  1Y3I A;  5DHU A;  1U7V B;  1KHX A;  2JQI A;  1K3N A;  1G6G A;  4KU0 D;  2LC1 A;  1J4P A;  4EGX A;  1Y3H A;  1UJX A;  5JEK A;  1YT5 A;  3VA4 A;  5JEM A;  2P1R A;  3ELV A;  3DIT A;  4DY6 A;  1YJM A;  3V7Y A;  1K3J A;  1J4L A;  1DEV A;  2I2F A;  2JQJ A;  3S40 A;  1QWT A;  2QVL A;  2BRF A;  3HUE A;  1MR1 A;  3VZD A;  5EJF A;  1ZOQ A;  5BVI A;  5DHP A;  1YJ5 C;  4D9V A;  1GXC A;  5C4V A;  1FHR A;  2I2A A;  5E50 A;  2AN1 A;  2EH0 A;  3VPY A;  3AFO A;  3UMZ A;  1J4O A;  3I6U A;  3UN0 A;  2I2B A;  3V8Q A;  2I29 A;  3V7W A;  5DHR A;  1WV3 A;  1YGS A;  4WER A;  3VZC A;  4H87 A;  1WLN A;  1K2M A;  2I2C A;  2KB3 A;  3FM8 A;  1LGQ A;  2FEZ A;  2FF4 A;  2KFU A;  1K3Q A;  4R9P A;  1J4Q A;  1U7V A;  5DJO A;  1MZK A;  1U7F B;  4HAO A;  5JEO A;  2I1W A;  1Z0S A;  2PIE A;  2G1L A;  4QCJ A;  5DHQ A;  1DD1 A;  1K2N A;  1KHU A;  3V7U A;  3T5P A;  3VA1 A;  4A4Y A;  3PO8 A;  1G88 A;  1Z0Z A;  4JIW D;  4JON A;  1SUW A;  3UOT A;  3GMJ A;  2CSW A;  3HUF A;  3HX1 A;  3ELS A;  2I2D A;  3VZB A;  4G2S A;  4WRR A;  2JPE A;  1R21 A;  3V8M A;  5EJG A;  3I6W A;  2KKL A;  3I0M A;  1J2F A;  3A77 A;  5JER A;  2QV7 A;  1LGP A;  5DHT A;  3GQS A;  1G3G A;  2BON A;  5JEJ A;  1MJS A;  2JGR A;  3UV0 A;  3KT9 A;  3V8P A;  3OUN A;  2AFF A;  1DMZ A;  1MK2 A;  3UNM A;  2JQL A;  3V8N A;  5A8I A;  5DHS A;  1QU5 A;  4JIV D;  5EJH A;  1Z0U A;  1U0T A;  1U7F A;  1UHT A;  4V24 A;  4EJQ A;  1J4K A;  2XXS A;  2JKD A;  3MDB A; 
#chains in the Genus database with same CATH homology
 2W3O A;  2XT9 B;  4L02 A;  1FHQ A;  3DSH A;  2A0T A;  2KB4 A;  3UNN A;  4A0E A;  5JEL A;  3POA A;  3I0N A;  1U7V B;  1KHX A;  2JQI A;  1K3N A;  1G6G A;  4KU0 D;  2LC1 A;  1J4P A;  4EGX A;  1UJX A;  5JEK A;  5JEM A;  3VA4 A;  2P1R A;  3ELV A;  3DIT A;  1YJM A;  1K3J A;  1J4L A;  1DEV A;  2JQJ A;  3S40 A;  1QWT A;  2QVL A;  2BRF A;  3HUE A;  1MR1 A;  3VZD A;  1ZOQ A;  5BVI A;  1YJ5 C;  4D9V A;  1GXC A;  5C4V A;  1FHR A;  5E50 A;  2EH0 A;  3VPY A;  3UMZ A;  1J4O A;  3I6U A;  3UN0 A;  1WV3 A;  1YGS A;  4WER A;  3VZC A;  4H87 A;  1WLN A;  1K2M A;  2KB3 A;  3FM8 A;  1LGQ A;  2FEZ A;  2FF4 A;  2KFU A;  1K3Q A;  4R9P A;  1J4Q A;  1U7V A;  5DJO A;  1MZK A;  1U7F B;  5JEO A;  2PIE A;  2G1L A;  4QCJ A;  1DD1 A;  1K2N A;  1KHU A;  3T5P A;  3VA1 A;  4A4Y A;  3PO8 A;  1G88 A;  4JIW D;  4JON A;  3UOT A;  3GMJ A;  2CSW A;  3HUF A;  3HX1 A;  3ELS A;  3VZB A;  4G2S A;  4WRR A;  2JPE A;  1R21 A;  3I6W A;  2KKL A;  3I0M A;  1J2F A;  3A77 A;  5JER A;  2QV7 A;  1LGP A;  1G3G A;  3GQS A;  2BON A;  5JEJ A;  1MJS A;  2JGR A;  3UV0 A;  3KT9 A;  3OUN A;  2AFF A;  1DMZ A;  1MK2 A;  3UNM A;  2JQL A;  5A8I A;  1QU5 A;  4JIV D;  1U7F A;  1UHT A;  4V24 A;  4EJQ A;  1J4K A;  2XXS A;  2JKD A;  3MDB A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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