5BVIA

X-ray structure of interferon regulatory factor 4 iad domain
Total Genus 48
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
48
sequence length
182
structure length
182
Chain Sequence
IRSAEALALSDCRLHICLYYRDILVKELTTTSPEGCRISHGHTYDVSNLDQVLFPYPDDNGQRKNIEKLLSHLERGLVLWMAPDGLYAKRLCQSRIYWDGPLALCSDRPNKLERDQTCKLFDTQQFLSELQVFAHHGRPAPRFQVTLCFGEEFPDPQRQRKLITAHVEPLLARQLYYFAQQN
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Structural Studies of IRF4 Reveal a Flexible Autoinhibitory Region and a Compact Linker Domain.
pubmed doi rcsb
molecule tags Transcription
source organism Mus musculus
molecule keywords Interferon regulatory factor 4
total genus 48
structure length 182
sequence length 182
chains with identical sequence B
ec nomenclature
pdb deposition date 2015-06-05

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF10401 IRF-3 Interferon-regulatory factor 3
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.60.200.10 Mainly Beta Sandwich Tumour Suppressor Smad4 Tumour Suppressor Smad4 5bviA00
1KHXA 5C4VA 5JEOA 5BVIA 1YGSA 1U7FA 3DSHA 1J2FA 1QWTA 1G88A 3GMJA 1DEVA 5JEMA 5JEJA 1MR1A 1MK2A 5JELA 1KHUA 1U7VB 5JEKA 4R9PA 1U7VA 1DD1A 3DITA 5JERA 1MJSA 1U7FB 1ZOQA 3A77A
chains in the Genus database with same CATH superfamily
3UN0A 5EJIA 4D9VA 1G3GA 1YJMA 5BVIA 3DSHA 2KB4A 4V24A 3T5PA 1WLNA 5EJHA 3S40A 1Z0SA 4JONA 4HAOA 2G1LA 2I2FA 5A8IA 5JELA 1R21A 4H87A 3VA1A 1MZKA 2AN1A 3UOTA 4R9PA 1K3NA 1G6GA 1WV3A 1SUWA 1U7VA 1DD1A 1J4LA 3VA4A 2EH0A 1U7FB 1Y3IA 1U0TA 3OUNA 1J4OA 1KHXA 1YJ5C 1J4QA 1J4PA 2FF4A 3ELSA 3V8NA 1YT5A 2LC1A 2P1RA 1DEVA 2KB3A 3ELVA 4WERA 3PO8A 4KU0D 4DY6A 1DMZA 1MK2A 1KHUA 2JPEA 1K3QA 3V7YA 1U0RA 1UJXA 2PIEA 3UNMA 2QV7A 2XT9B 4A0EA 1QU5A 2I2DA 5E50A 5DHTA 1J4KA 2QVLA 2JQLA 3A77A 3V7WA 1K2NA 3PFNA 5C4VA 2I29A 5JEOA 2A0TA 1Z0ZA 1U7FA 2I2AA 1QWTA 3UNNA 2Q5FA 5DHPA 4L02A 4A4YA 4JIVD 3VPYA 3V8PA 5JEJA 1GXCA 1MR1A 3KT9A 3FM8A 2AFFA 2JQIA 3GQSA 3HX1A 2KFUA 1LGQA 5JEKA 1LGPA 4WRRA 2I2CA 2KKLA 3HUFA 3POAA 3V8RA 1FHRA 3V8MA 5DJOA 3DITA 5DHRA 5JERA 1MJSA 3VZCA 3I6UA 2JQJA 5EJFA 2W3OA 1FHQA 3HUEA 1YGSA 1UHTA 1Y3HA 4G2SA 4JIWD 3VZDA 3UMZA 4QCJA 2CSWA 3AFOA 1J2FA 1G88A 2XXSA 5EJGA 4EJQA 2I2BA 3I0MA 3GMJA 3I6WA 5JEMA 5DHSA 5DHQA 2JGRA 2BRFA 3UV0A 1K2MA 3I0NA 3VZBA 1U7VB 3V80A 3V7UA 3MDBA 1Z0UA 2JKDA 5DHUA 2BONA 2I1WA 4EGXA 1ZOQA 3V8QA 2FEZA 1K3JA
chains in the Genus database with same CATH topology
3UN0A 1G3GA 4D9VA 1YJMA 5BVIA 3DSHA 2KB4A 4V24A 3T5PA 1WLNA 3S40A 4JONA 2G1LA 5A8IA 5JELA 1R21A 4H87A 3VA1A 1MZKA 3UOTA 4R9PA 1K3NA 1G6GA 1WV3A 1U7VA 1DD1A 1J4LA 3VA4A 2EH0A 1U7FB 3OUNA 1J4OA 1KHXA 1YJ5C 1J4QA 1J4PA 2FF4A 3ELSA 2LC1A 2P1RA 1DEVA 2KB3A 3ELVA 4WERA 3PO8A 4KU0D 1DMZA 1MK2A 1KHUA 2JPEA 1K3QA 1UJXA 2PIEA 3UNMA 2QV7A 2XT9B 4A0EA 1QU5A 5E50A 1J4KA 3A77A 2QVLA 2JQLA 1K2NA 5C4VA 5JEOA 2A0TA 1U7FA 1QWTA 3UNNA 4L02A 4A4YA 4JIVD 3VPYA 5JEJA 1GXCA 1MR1A 3KT9A 3FM8A 2AFFA 2JQIA 3GQSA 3HX1A 2KFUA 1LGQA 5JEKA 1LGPA 4WRRA 2KKLA 3HUFA 3POAA 1FHRA 5DJOA 3DITA 5JERA 1MJSA 3VZCA 3I6UA 2JQJA 2W3OA 1FHQA 3HUEA 1YGSA 1UHTA 4G2SA 4JIWD 3VZDA 3UMZA 4QCJA 2CSWA 1J2FA 1G88A 2XXSA 4EJQA 3I0MA 3GMJA 3I6WA 5JEMA 2JGRA 2BRFA 3UV0A 1K2MA 3I0NA 3VZBA 1U7VB 3MDBA 2JKDA 2BONA 4EGXA 1ZOQA 2FEZA 1K3JA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1KHX A;  5C4V A;  5JEO A;  5BVI A;  1YGS A;  1U7F A;  3DSH A;  1J2F A;  1QWT A;  1G88 A;  3GMJ A;  1DEV A;  5JEM A;  5JEJ A;  1MR1 A;  1MK2 A;  5JEL A;  1KHU A;  1U7V B;  5JEK A;  4R9P A;  1U7V A;  1DD1 A;  3DIT A;  5JER A;  1MJS A;  1U7F B;  1ZOQ A;  3A77 A; 
#chains in the Genus database with same CATH topology
 3UN0 A;  5EJI A;  4D9V A;  1G3G A;  1YJM A;  5BVI A;  3DSH A;  2KB4 A;  4V24 A;  3T5P A;  1WLN A;  5EJH A;  3S40 A;  1Z0S A;  4JON A;  4HAO A;  2G1L A;  2I2F A;  5A8I A;  5JEL A;  1R21 A;  4H87 A;  3VA1 A;  1MZK A;  2AN1 A;  3UOT A;  4R9P A;  1K3N A;  1G6G A;  1WV3 A;  1SUW A;  1U7V A;  1DD1 A;  1J4L A;  3VA4 A;  2EH0 A;  1U7F B;  1Y3I A;  1U0T A;  3OUN A;  1J4O A;  1KHX A;  1YJ5 C;  1J4Q A;  1J4P A;  2FF4 A;  3ELS A;  3V8N A;  1YT5 A;  2LC1 A;  2P1R A;  1DEV A;  2KB3 A;  3ELV A;  4WER A;  3PO8 A;  4KU0 D;  4DY6 A;  1DMZ A;  1MK2 A;  1KHU A;  2JPE A;  1K3Q A;  3V7Y A;  1U0R A;  1UJX A;  2PIE A;  3UNM A;  2QV7 A;  2XT9 B;  4A0E A;  1QU5 A;  2I2D A;  5E50 A;  5DHT A;  1J4K A;  2QVL A;  2JQL A;  3A77 A;  3V7W A;  1K2N A;  3PFN A;  5C4V A;  2I29 A;  5JEO A;  2A0T A;  1Z0Z A;  1U7F A;  2I2A A;  1QWT A;  3UNN A;  2Q5F A;  5DHP A;  4L02 A;  4A4Y A;  4JIV D;  3VPY A;  3V8P A;  5JEJ A;  1GXC A;  1MR1 A;  3KT9 A;  3FM8 A;  2AFF A;  2JQI A;  3GQS A;  3HX1 A;  2KFU A;  1LGQ A;  5JEK A;  1LGP A;  4WRR A;  2I2C A;  2KKL A;  3HUF A;  3POA A;  3V8R A;  1FHR A;  3V8M A;  5DJO A;  3DIT A;  5DHR A;  5JER A;  1MJS A;  3VZC A;  3I6U A;  2JQJ A;  5EJF A;  2W3O A;  1FHQ A;  3HUE A;  1YGS A;  1UHT A;  1Y3H A;  4G2S A;  4JIW D;  3VZD A;  3UMZ A;  4QCJ A;  2CSW A;  3AFO A;  1J2F A;  1G88 A;  2XXS A;  5EJG A;  4EJQ A;  2I2B A;  3I0M A;  3GMJ A;  3I6W A;  5JEM A;  5DHS A;  5DHQ A;  2JGR A;  2BRF A;  3UV0 A;  1K2M A;  3I0N A;  3VZB A;  1U7V B;  3V80 A;  3V7U A;  3MDB A;  1Z0U A;  2JKD A;  5DHU A;  2BON A;  2I1W A;  4EGX A;  1ZOQ A;  3V8Q A;  2FEZ A;  1K3J A; 
#chains in the Genus database with same CATH homology
 3UN0 A;  1G3G A;  4D9V A;  1YJM A;  5BVI A;  3DSH A;  2KB4 A;  4V24 A;  3T5P A;  1WLN A;  3S40 A;  4JON A;  2G1L A;  5A8I A;  5JEL A;  1R21 A;  4H87 A;  3VA1 A;  1MZK A;  3UOT A;  4R9P A;  1K3N A;  1G6G A;  1WV3 A;  1U7V A;  1DD1 A;  1J4L A;  3VA4 A;  2EH0 A;  1U7F B;  3OUN A;  1J4O A;  1KHX A;  1YJ5 C;  1J4Q A;  1J4P A;  2FF4 A;  3ELS A;  2LC1 A;  2P1R A;  1DEV A;  2KB3 A;  3ELV A;  4WER A;  3PO8 A;  4KU0 D;  1DMZ A;  1MK2 A;  1KHU A;  2JPE A;  1K3Q A;  1UJX A;  2PIE A;  3UNM A;  2QV7 A;  2XT9 B;  4A0E A;  1QU5 A;  5E50 A;  1J4K A;  3A77 A;  2QVL A;  2JQL A;  1K2N A;  5C4V A;  5JEO A;  2A0T A;  1U7F A;  1QWT A;  3UNN A;  4L02 A;  4A4Y A;  4JIV D;  3VPY A;  5JEJ A;  1GXC A;  1MR1 A;  3KT9 A;  3FM8 A;  2AFF A;  2JQI A;  3GQS A;  3HX1 A;  2KFU A;  1LGQ A;  5JEK A;  1LGP A;  4WRR A;  2KKL A;  3HUF A;  3POA A;  1FHR A;  5DJO A;  3DIT A;  5JER A;  1MJS A;  3VZC A;  3I6U A;  2JQJ A;  2W3O A;  1FHQ A;  3HUE A;  1YGS A;  1UHT A;  4G2S A;  4JIW D;  3VZD A;  3UMZ A;  4QCJ A;  2CSW A;  1J2F A;  1G88 A;  2XXS A;  4EJQ A;  3I0M A;  3GMJ A;  3I6W A;  5JEM A;  2JGR A;  2BRF A;  3UV0 A;  1K2M A;  3I0N A;  3VZB A;  1U7V B;  3MDB A;  2JKD A;  2BON A;  4EGX A;  1ZOQ A;  2FEZ A;  1K3J A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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