The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.
Total Genus |
33
|
sequence length |
116
|
structure length |
116
|
Chain Sequence |
PWARLWALQDGFANLECVNDNYWFGRDKSCEYCFDEPLLKRTDKYRTYSKKHFRIFREVGPKNSYIAYIEDHSGNGTFVNTELVGKGKRRPLNNNSEIALSLSRNKVFVFFDLTVD
|
The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.
After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.
| publication title |
Structural and Functional Versatility of the Fha Domain in DNA-Damage Signaling by the Tumor Suppressor Kinase Chk2
pubmed doi rcsb |
| molecule keywords |
SERINE/THREONINE-PROTEIN KINASE CHK2
|
| molecule tags |
Phosphoprotein-binding domain
|
| source organism |
Homo sapiens
|
| total genus |
33
|
| structure length |
116
|
| sequence length |
116
|
| chains with identical sequence |
D, G, J
|
| ec nomenclature |
ec
2.7.11.1: Non-specific serine/threonine protein kinase. |
| pdb deposition date | 2002-04-02 |
| chain | Pfam Accession Code | Pfam Family Identifier | Pfam Description |
|---|---|---|---|
| A | PF00498 | FHA | FHA domain |
Image from the rcsb pdb (www.rcsb.org)
cath code
| Class | Architecture | Topology | Homology | Domain |
|---|---|---|---|---|---|
| Mainly Beta | Sandwich | Tumour Suppressor Smad4 | Tumour Suppressor Smad4 |
#chains in the Genus database with same CATH superfamily 4EGX A; 4G2S A; 1YJM A; 2W3O A; 2CSW A; 2KB3 A; 5DJO A; 1LGP A; 3FM8 A; 1WV3 A; 3HX1 A; 3I0M A; 2XT9 B; 3UOT A; 1J4O A; 1G3G A; 1FHR A; 3VA1 A; 1WLN A; 1FHQ A; 3UNN A; 1K3N A; 3HUE A; 2JQJ A; 2EH0 A; 1K2M A; 2BRF A; 4JON A; 2A0T A; 2FEZ A; 3I6W A; 3I6U A; 3UNM A; 1K2N A; 3OUN A; 5A8I A; 2LC1 A; 3VPY A; 4D9V A; 3I0N A; 3MDB A; 5E50 A; 3UMZ A; 4H87 A; 1GXC A; 3ELV A; 4A0E A; 1DMZ A; 1K3J A; 3UN0 A; 1R21 A; 3ELS A; 1LGQ A; 4QCJ A; 1J4P A; 2KFU A; 1G6G A; 3GQS A; 1J4K A; 1J4L A; 1UHT A; 2JQL A; 2PIE A; 1K3Q A; 2KKL A; 2AFF A; 3UV0 A; 2JKD A; 1UJX A; 2JQI A; 3VA4 A; 2JPE A; 1YJ5 C; 2KB4 A; 1MZK A; 2FF4 A; 1QU5 A; 3HUF A; 1J4Q A; 3PO8 A; 4EJQ A; 3KT9 A; 2G1L A; 3POA A; #chains in the Genus database with same CATH topology 1G88 A; 4EGX A; 3A77 A; 1KHX A; 3PFN A; 4G2S A; 5DHR A; 1YJM A; 2W3O A; 1U7V A; 5JER A; 2CSW A; 2KB3 A; 2I2F A; 5DJO A; 5EJI A; 1LGP A; 2I2D A; 3FM8 A; 1WV3 A; 1DEV A; 1Z0Z A; 2P1R A; 3V7W A; 5EJF A; 1J2F A; 3HX1 A; 3I0M A; 2XT9 B; 3UOT A; 1J4O A; 1G3G A; 1KHU A; 2I1W A; 5DHQ A; 1SUW A; 1FHR A; 2AN1 A; 3VA1 A; 1Z0S A; 1WLN A; 3AFO A; 5JEO A; 1Y3I A; 1FHQ A; 3UNN A; 1K3N A; 3HUE A; 2JQJ A; 3VZD A; 4HAO A; 2EH0 A; 1K2M A; 1ZOQ A; 1Z0U A; 2BRF A; 2I2C A; 4JON A; 2A0T A; 3DSH A; 5DHT A; 5BVI A; 1QWT A; 2FEZ A; 1Y3H A; 1U7V B; 3S40 A; 1MJS A; 3I6W A; 3V7U A; 3I6U A; 3UNM A; 5EJG A; 1K2N A; 3OUN A; 5A8I A; 2LC1 A; 3VPY A; 1U0T A; 1MK2 A; 2BON A; 4D9V A; 3I0N A; 1DD1 A; 1U7F A; 5JEJ A; 3MDB A; 5E50 A; 1U0R A; 5DHP A; 3UMZ A; 4H87 A; 3DIT A; 1YT5 A; 4JIW D; 1GXC A; 3ELV A; 5JEL A; 4WER A; 5DHU A; 5C4V A; 4A0E A; 1DMZ A; 1K3J A; 2QVL A; 3UN0 A; 3V80 A; 1R21 A; 2Q5F A; 4L02 A; 3ELS A; 1LGQ A; 4KU0 D; 4DY6 A; 4JIV D; 4WRR A; 4QCJ A; 3V8N A; 4A4Y A; 1J4P A; 2KFU A; 1G6G A; 3GQS A; 1MR1 A; 1YGS A; 1J4K A; 3T5P A; 3GMJ A; 5DHS A; 3V8M A; 1J4L A; 1UHT A; 2JQL A; 2PIE A; 1K3Q A; 2KKL A; 2AFF A; 2I2A A; 5JEK A; 3UV0 A; 2JKD A; 1UJX A; 2I29 A; 2JQI A; 3V8R A; 3VA4 A; 5JEM A; 2JGR A; 1U7F B; 2JPE A; 1YJ5 C; 2KB4 A; 3V7Y A; 3VZB A; 4R9P A; 1MZK A; 2FF4 A; 1QU5 A; 3HUF A; 3V8Q A; 1J4Q A; 2I2B A; 3PO8 A; 3VZC A; 2XXS A; 4EJQ A; 2QV7 A; 4V24 A; 3KT9 A; 2G1L A; 5EJH A; 3V8P A; 3POA A; #chains in the Genus database with same CATH homology 1G88 A; 4EGX A; 3A77 A; 1KHX A; 4G2S A; 1YJM A; 2W3O A; 1U7V A; 5JER A; 2CSW A; 2KB3 A; 5DJO A; 1LGP A; 3FM8 A; 1WV3 A; 1DEV A; 2P1R A; 1J2F A; 3HX1 A; 3I0M A; 2XT9 B; 3UOT A; 1J4O A; 1G3G A; 1KHU A; 1FHR A; 3VA1 A; 1WLN A; 5JEO A; 1FHQ A; 3UNN A; 1K3N A; 3HUE A; 2JQJ A; 3VZD A; 2EH0 A; 1K2M A; 1ZOQ A; 2BRF A; 4JON A; 2A0T A; 3DSH A; 5BVI A; 1QWT A; 2FEZ A; 1U7V B; 3S40 A; 1MJS A; 3I6W A; 3I6U A; 3UNM A; 1K2N A; 3OUN A; 5A8I A; 2LC1 A; 3VPY A; 1MK2 A; 2BON A; 4D9V A; 3I0N A; 1DD1 A; 1U7F A; 5JEJ A; 3MDB A; 5E50 A; 3UMZ A; 4H87 A; 3DIT A; 4JIW D; 1GXC A; 3ELV A; 5JEL A; 4WER A; 4A0E A; 1DMZ A; 1K3J A; 2QVL A; 3UN0 A; 1R21 A; 4L02 A; 3ELS A; 1LGQ A; 4KU0 D; 4JIV D; 4WRR A; 4QCJ A; 4A4Y A; 1J4P A; 2KFU A; 1G6G A; 3GQS A; 1MR1 A; 1YGS A; 1J4K A; 3T5P A; 3GMJ A; 1J4L A; 1UHT A; 2JQL A; 2PIE A; 1K3Q A; 2KKL A; 2AFF A; 5JEK A; 3UV0 A; 2JKD A; 1UJX A; 2JQI A; 3VA4 A; 5JEM A; 2JGR A; 1U7F B; 2JPE A; 1YJ5 C; 2KB4 A; 3VZB A; 4R9P A; 1MZK A; 2FF4 A; 1QU5 A; 3HUF A; 1J4Q A; 3PO8 A; 3VZC A; 2XXS A; 4EJQ A; 2QV7 A; 4V24 A; 3KT9 A; 2G1L A; 5C4V A; 3POA A;
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