1J4LA

Solution structure of the fha2 domain of rad53 complexed with a phosphothreonyl peptide derived from rad9
Total Genus 23
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
23
sequence length
158
structure length
158
Chain Sequence
GNGRFLTLKPLPDSIIQESLEIQQGVNPFFIGRSEDCNCKIEDNRLSRVHCFIFKKRHAVGKSMYESPAQGLDDIWYCHTGTNVSYLNNNRMIQGTKFLLQDGDEIKIIWDKNNKFVIGFKVEINDTTGLFNEGLGMLQEQRVVLKQTAEEKDLVKKL
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

molecule tags Transferase
source organism Saccharomyces cerevisiae
publication title Solution structure of the yeast Rad53 FHA2 complexed with a phosphothreonine peptide pTXXL: comparison with the structures of FHA2-pYXL and FHA1-pTXXD complexes.
pubmed doi rcsb
molecule keywords PROTEIN KINASE SPK1
total genus 23
structure length 158
sequence length 158
ec nomenclature ec 2.7.12.1: Dual-specificity kinase.
pdb deposition date 2001-10-03

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00498 FHA FHA domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.60.200.20 Mainly Beta Sandwich Tumour Suppressor Smad4 Tumour Suppressor Smad4 1j4lA00
1GXCA 2CSWA 3UNNA 2AFFA 1K2NA 3I0MA 3I0NA 2JQLA 1J4QA 5E50A 1UHTA 3VA1A 1K2MA 3UV0A 1R21A 1G3GA 4D9VA 1J4PA 1J4KA 4EGXA 5DJOA 3MDBA 1LGQA 1YJ5C 3FM8A 3OUNA 4EJQA 1K3QA 2JKDA 3PO8A 3VPYA 3I6WA 1WV3A 2FF4A 4G2SA 2KKLA 1J4LA 1K3NA 2EH0A 1FHQA 3ELVA 1QU5A 1K3JA 2JQJA 1J4OA 4JONA 3ELSA 3UOTA 2A0TA 3UNMA 3HX1A 5A8IA 3HUFA 1MZKA 2W3OA 3VA4A 4H87A 2XT9B 1G6GA 2LC1A 3POAA 4QCJA 1LGPA 3GQSA 2KB3A 1WLNA 2BRFA 3I6UA 2FEZA 1FHRA 2JQIA 2KFUA 1DMZA 3HUEA 2KB4A 2PIEA 3KT9A 2G1LA 3UN0A 2JPEA 4A0EA 1UJXA 3UMZA 1YJMA
chains in the Genus database with same CATH superfamily
1GXCA 2CSWA 3V7YA 3UNNA 2AFFA 1K2NA 2I2CA 3I0MA 2P1RA 1U7FA 3DITA 3I0NA 2JQLA 1MR1A 1QWTA 3VZDA 3V8RA 4KU0D 1J4QA 5E50A 1UHTA 2QV7A 3V8NA 3VA1A 1K2MA 1DD1A 3UV0A 4L02A 1R21A 1G3GA 5EJHA 3DSHA 4D9VA 1KHUA 1U0RA 1J4PA 4JIWD 1J4KA 1Z0ZA 4WERA 3T5PA 2XXSA 1J2FA 5JERA 5DHRA 3V80A 5DHSA 4DY6A 5DJOA 4EGXA 2BONA 3MDBA 1U7VB 1LGQA 4JIVD 3VZBA 1YJ5C 3FM8A 3OUNA 2I1WA 4R9PA 4EJQA 5DHQA 1K3QA 2JKDA 3PO8A 1Z0UA 3V8MA 5DHUA 1MJSA 3VPYA 3I6WA 1WV3A 3GMJA 1Z0SA 3A77A 2FF4A 4G2SA 2KKLA 2QVLA 1J4LA 1K3NA 2EH0A 1SUWA 5BVIA 1FHQA 3ELVA 3V7WA 1QU5A 1K3JA 3S40A 3AFOA 2JQJA 1J4OA 4JONA 1MK2A 1YGSA 3ELSA 3UOTA 2A0TA 4HAOA 3PFNA 3UNMA 3HX1A 5DHPA 5DHTA 3V8QA 4V24A 3V8PA 5A8IA 3HUFA 1MZKA 1Y3HA 1Y3IA 1G88A 1ZOQA 5EJFA 2JGRA 2W3OA 3VA4A 4H87A 1KHXA 2I2DA 2XT9B 2I2BA 1G6GA 5JEMA 5JEOA 1YT5A 2LC1A 4A4YA 3POAA 5JELA 4QCJA 1U7VA 1U0TA 2I2AA 2Q5FA 5JEKA 1LGPA 3GQSA 2KB3A 5JEJA 1WLNA 2BRFA 3I6UA 2FEZA 1FHRA 2JQIA 1U7FB 2I2FA 2KFUA 4WRRA 2I29A 1DMZA 3HUEA 2KB4A 2PIEA 5EJIA 1DEVA 3KT9A 2G1LA 5C4VA 3UN0A 2JPEA 2AN1A 5EJGA 3VZCA 3V7UA 4A0EA 1UJXA 3UMZA 1YJMA
chains in the Genus database with same CATH topology
1GXCA 2CSWA 3UNNA 2AFFA 1K2NA 3I0MA 2P1RA 1U7FA 3DITA 3I0NA 2JQLA 1MR1A 1QWTA 3VZDA 4KU0D 1J4QA 5E50A 1UHTA 2QV7A 3VA1A 1K2MA 1DD1A 3UV0A 4L02A 1R21A 1G3GA 3DSHA 4D9VA 1KHUA 1J4PA 4JIWD 1J4KA 4WERA 3T5PA 2XXSA 1J2FA 5JERA 4EGXA 5DJOA 2BONA 3MDBA 1U7VB 1LGQA 4JIVD 3VZBA 1YJ5C 3FM8A 3OUNA 4R9PA 4EJQA 1K3QA 2JKDA 3PO8A 1MJSA 3VPYA 3I6WA 1WV3A 3GMJA 3A77A 2FF4A 4G2SA 2KKLA 2QVLA 1J4LA 1K3NA 2EH0A 5BVIA 1FHQA 3ELVA 1QU5A 1K3JA 3S40A 2JQJA 1J4OA 4JONA 1MK2A 1YGSA 3ELSA 3UOTA 2A0TA 3UNMA 3HX1A 4V24A 5A8IA 3HUFA 1MZKA 1G88A 1ZOQA 2JGRA 2W3OA 3VA4A 4H87A 1KHXA 2XT9B 5JEMA 5JEOA 1G6GA 2LC1A 4A4YA 3POAA 5JELA 4QCJA 1U7VA 5JEKA 1LGPA 3GQSA 2KB3A 5JEJA 1WLNA 2BRFA 3I6UA 2FEZA 1FHRA 2JQIA 1U7FB 2KFUA 4WRRA 1DMZA 3HUEA 2KB4A 2PIEA 1DEVA 3KT9A 2G1LA 5C4VA 3UN0A 2JPEA 3VZCA 4A0EA 1UJXA 3UMZA 1YJMA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1GXC A;  2CSW A;  3UNN A;  2AFF A;  1K2N A;  3I0M A;  3I0N A;  2JQL A;  1J4Q A;  5E50 A;  1UHT A;  3VA1 A;  1K2M A;  3UV0 A;  1R21 A;  1G3G A;  4D9V A;  1J4P A;  1J4K A;  4EGX A;  5DJO A;  3MDB A;  1LGQ A;  1YJ5 C;  3FM8 A;  3OUN A;  4EJQ A;  1K3Q A;  2JKD A;  3PO8 A;  3VPY A;  3I6W A;  1WV3 A;  2FF4 A;  4G2S A;  2KKL A;  1J4L A;  1K3N A;  2EH0 A;  1FHQ A;  3ELV A;  1QU5 A;  1K3J A;  2JQJ A;  1J4O A;  4JON A;  3ELS A;  3UOT A;  2A0T A;  3UNM A;  3HX1 A;  5A8I A;  3HUF A;  1MZK A;  2W3O A;  3VA4 A;  4H87 A;  2XT9 B;  1G6G A;  2LC1 A;  3POA A;  4QCJ A;  1LGP A;  3GQS A;  2KB3 A;  1WLN A;  2BRF A;  3I6U A;  2FEZ A;  1FHR A;  2JQI A;  2KFU A;  1DMZ A;  3HUE A;  2KB4 A;  2PIE A;  3KT9 A;  2G1L A;  3UN0 A;  2JPE A;  4A0E A;  1UJX A;  3UMZ A;  1YJM A; 
#chains in the Genus database with same CATH topology
 1GXC A;  2CSW A;  3V7Y A;  3UNN A;  2AFF A;  1K2N A;  2I2C A;  3I0M A;  2P1R A;  1U7F A;  3DIT A;  3I0N A;  2JQL A;  1MR1 A;  1QWT A;  3VZD A;  3V8R A;  4KU0 D;  1J4Q A;  5E50 A;  1UHT A;  2QV7 A;  3V8N A;  3VA1 A;  1K2M A;  1DD1 A;  3UV0 A;  4L02 A;  1R21 A;  1G3G A;  5EJH A;  3DSH A;  4D9V A;  1KHU A;  1U0R A;  1J4P A;  4JIW D;  1J4K A;  1Z0Z A;  4WER A;  3T5P A;  2XXS A;  1J2F A;  5JER A;  5DHR A;  3V80 A;  5DHS A;  4DY6 A;  5DJO A;  4EGX A;  2BON A;  3MDB A;  1U7V B;  1LGQ A;  4JIV D;  3VZB A;  1YJ5 C;  3FM8 A;  3OUN A;  2I1W A;  4R9P A;  4EJQ A;  5DHQ A;  1K3Q A;  2JKD A;  3PO8 A;  1Z0U A;  3V8M A;  5DHU A;  1MJS A;  3VPY A;  3I6W A;  1WV3 A;  3GMJ A;  1Z0S A;  3A77 A;  2FF4 A;  4G2S A;  2KKL A;  2QVL A;  1J4L A;  1K3N A;  2EH0 A;  1SUW A;  5BVI A;  1FHQ A;  3ELV A;  3V7W A;  1QU5 A;  1K3J A;  3S40 A;  3AFO A;  2JQJ A;  1J4O A;  4JON A;  1MK2 A;  1YGS A;  3ELS A;  3UOT A;  2A0T A;  4HAO A;  3PFN A;  3UNM A;  3HX1 A;  5DHP A;  5DHT A;  3V8Q A;  4V24 A;  3V8P A;  5A8I A;  3HUF A;  1MZK A;  1Y3H A;  1Y3I A;  1G88 A;  1ZOQ A;  5EJF A;  2JGR A;  2W3O A;  3VA4 A;  4H87 A;  1KHX A;  2I2D A;  2XT9 B;  2I2B A;  1G6G A;  5JEM A;  5JEO A;  1YT5 A;  2LC1 A;  4A4Y A;  3POA A;  5JEL A;  4QCJ A;  1U7V A;  1U0T A;  2I2A A;  2Q5F A;  5JEK A;  1LGP A;  3GQS A;  2KB3 A;  5JEJ A;  1WLN A;  2BRF A;  3I6U A;  2FEZ A;  1FHR A;  2JQI A;  1U7F B;  2I2F A;  2KFU A;  4WRR A;  2I29 A;  1DMZ A;  3HUE A;  2KB4 A;  2PIE A;  5EJI A;  1DEV A;  3KT9 A;  2G1L A;  5C4V A;  3UN0 A;  2JPE A;  2AN1 A;  5EJG A;  3VZC A;  3V7U A;  4A0E A;  1UJX A;  3UMZ A;  1YJM A; 
#chains in the Genus database with same CATH homology
 1GXC A;  2CSW A;  3UNN A;  2AFF A;  1K2N A;  3I0M A;  2P1R A;  1U7F A;  3DIT A;  3I0N A;  2JQL A;  1MR1 A;  1QWT A;  3VZD A;  4KU0 D;  1J4Q A;  5E50 A;  1UHT A;  2QV7 A;  3VA1 A;  1K2M A;  1DD1 A;  3UV0 A;  4L02 A;  1R21 A;  1G3G A;  3DSH A;  4D9V A;  1KHU A;  1J4P A;  4JIW D;  1J4K A;  4WER A;  3T5P A;  2XXS A;  1J2F A;  5JER A;  4EGX A;  5DJO A;  2BON A;  3MDB A;  1U7V B;  1LGQ A;  4JIV D;  3VZB A;  1YJ5 C;  3FM8 A;  3OUN A;  4R9P A;  4EJQ A;  1K3Q A;  2JKD A;  3PO8 A;  1MJS A;  3VPY A;  3I6W A;  1WV3 A;  3GMJ A;  3A77 A;  2FF4 A;  4G2S A;  2KKL A;  2QVL A;  1J4L A;  1K3N A;  2EH0 A;  5BVI A;  1FHQ A;  3ELV A;  1QU5 A;  1K3J A;  3S40 A;  2JQJ A;  1J4O A;  4JON A;  1MK2 A;  1YGS A;  3ELS A;  3UOT A;  2A0T A;  3UNM A;  3HX1 A;  4V24 A;  5A8I A;  3HUF A;  1MZK A;  1G88 A;  1ZOQ A;  2JGR A;  2W3O A;  3VA4 A;  4H87 A;  1KHX A;  2XT9 B;  5JEM A;  5JEO A;  1G6G A;  2LC1 A;  4A4Y A;  3POA A;  5JEL A;  4QCJ A;  1U7V A;  5JEK A;  1LGP A;  3GQS A;  2KB3 A;  5JEJ A;  1WLN A;  2BRF A;  3I6U A;  2FEZ A;  1FHR A;  2JQI A;  1U7F B;  2KFU A;  4WRR A;  1DMZ A;  3HUE A;  2KB4 A;  2PIE A;  1DEV A;  3KT9 A;  2G1L A;  5C4V A;  3UN0 A;  2JPE A;  3VZC A;  4A0E A;  1UJX A;  3UMZ A;  1YJM A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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