1YJ5C

Molecular architecture of mammalian polynucleotide kinase, a dna repair enzyme
Total Genus 14
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
14
sequence length
105
structure length
105
Chain Sequence
SRGRLWLQSPTGGPPPIFLPSDGQALVLGRGPLTQVTDRKCSRNQVELIADPESRTVAVKQLGVNPSTVGVHELKPGLSGSLSLGDVLYLVNGLYPLTLRWEELS
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Transferase
source organism Mus musculus
publication title The molecular architecture of the mammalian DNA repair enzyme, polynucleotide kinase.
pubmed doi rcsb
molecule keywords 5' polynucleotide kinase-3' phosphatase catalytic domain
total genus 14
structure length 105
sequence length 105
ec nomenclature ec 2.7.1.78: Polynucleotide 5'-hydroxyl-kinase.
pdb deposition date 2005-01-13

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
C PF17913 FHA_2 FHA domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.60.200.20 Mainly Beta Sandwich Tumour Suppressor Smad4 Tumour Suppressor Smad4 1yj5C00
2JQJA 2JQIA 1G3GA 1K2NA 3UMZA 2XT9B 2FF4A 3KT9A 3I6UA 2KB3A 2JQLA 3UNNA 3HX1A 2KKLA 1K2MA 2PIEA 4D9VA 2W3OA 2EH0A 3ELVA 3FM8A 3I0MA 1WV3A 3UNMA 4A0EA 1FHRA 3POAA 2G1LA 1YJ5C 1FHQA 5DJOA 1UHTA 3MDBA 3VA4A 3HUFA 2JPEA 1J4LA 1J4PA 5A8IA 1LGPA 3UV0A 1G6GA 1DMZA 1QU5A 3I6WA 2LC1A 3OUNA 1J4OA 1K3QA 3I0NA 1MZKA 4H87A 1K3NA 1UJXA 3ELSA 2KB4A 3VA1A 4JONA 3UOTA 1J4QA 4QCJA 3HUEA 1LGQA 5E50A 3VPYA 2KFUA 1J4KA 2A0TA 4G2SA 2AFFA 1GXCA 3UN0A 2BRFA 1R21A 1YJMA 2CSWA 4EJQA 2FEZA 3PO8A 4EGXA 2JKDA 3GQSA 1K3JA 1WLNA
chains in the Genus database with same CATH superfamily
3V8PA 2JQJA 2JQIA 4V24A 3V8NA 2I29A 2I2DA 5JEMA 4KU0D 2I2BA 5DHSA 1KHUA 3V8RA 1G3GA 5JELA 1K2NA 4R9PA 3UMZA 2XT9B 2FF4A 3KT9A 5JEJA 3I6UA 2KB3A 4WERA 2JQLA 3UNNA 1YGSA 2QV7A 3HX1A 2KKLA 1K2MA 2PIEA 4D9VA 2W3OA 2EH0A 3ELVA 3FM8A 1U7FB 3VZCA 3I0MA 3V8QA 5JEOA 1WV3A 3UNMA 4A0EA 4HAOA 1FHRA 1ZOQA 2I1WA 3POAA 2G1LA 1Z0UA 2QVLA 5DHUA 1YJ5C 2I2CA 1FHQA 5DJOA 3VZDA 1UHTA 3MDBA 3VA4A 1MJSA 4A4YA 3HUFA 3GMJA 5EJGA 3V7WA 5EJFA 2I2AA 2JPEA 5DHQA 1J4LA 1G88A 1YT5A 1KHXA 1J4PA 5A8IA 2I2FA 1LGPA 5DHPA 3UV0A 1G6GA 3V7YA 1DMZA 1QU5A 5C4VA 2LC1A 3I6WA 5JERA 3DITA 1MK2A 1Y3IA 1J4OA 3OUNA 3I0NA 1MZKA 1U0RA 4H87A 5DHTA 1K3NA 5BVIA 1K3QA 1UJXA 3ELSA 3PFNA 2KB4A 3VA1A 4JONA 3V8MA 3UOTA 3VZBA 3DSHA 4DY6A 1J4QA 1J2FA 1U7VA 4QCJA 3HUEA 1LGQA 5EJIA 4L02A 5E50A 3VPYA 3T5PA 2KFUA 1J4KA 2A0TA 4G2SA 5DHRA 2AFFA 1GXCA 2XXSA 2AN1A 3UN0A 2P1RA 2BRFA 1R21A 2Q5FA 1YJMA 1DEVA 1U0TA 2JGRA 3V80A 2CSWA 4JIVD 4EJQA 2BONA 2FEZA 3PO8A 4JIWD 4EGXA 1MR1A 1Y3HA 1SUWA 3V7UA 5EJHA 1U7VB 3A77A 1Z0ZA 5JEKA 1DD1A 2JKDA 1QWTA 3S40A 3GQSA 1U7FA 1K3JA 1WLNA 1Z0SA 4WRRA 3AFOA
chains in the Genus database with same CATH topology
2JQJA 2JQIA 4V24A 5JEMA 4KU0D 1KHUA 1G3GA 5JELA 1K2NA 4R9PA 3UMZA 2XT9B 2FF4A 3KT9A 5JEJA 3I6UA 2KB3A 4WERA 2JQLA 3UNNA 1YGSA 2QV7A 3HX1A 2KKLA 1K2MA 2PIEA 4D9VA 2W3OA 2EH0A 3ELVA 3FM8A 1U7FB 3VZCA 3I0MA 5JEOA 1WV3A 3UNMA 4A0EA 1FHRA 1ZOQA 3POAA 2G1LA 2QVLA 1YJ5C 1FHQA 5DJOA 3VZDA 1UHTA 3MDBA 3VA4A 1MJSA 4A4YA 3HUFA 3GMJA 2JPEA 1J4LA 1G88A 1KHXA 1J4PA 5A8IA 1LGPA 3UV0A 1G6GA 1DMZA 1QU5A 5C4VA 3I6WA 2LC1A 5JERA 3DITA 1MK2A 3OUNA 1J4OA 1K3QA 3I0NA 1MZKA 4H87A 1K3NA 5BVIA 1UJXA 3ELSA 2KB4A 3VA1A 4JONA 3UOTA 3VZBA 3DSHA 1J4QA 1J2FA 1U7VA 4QCJA 3HUEA 1LGQA 4L02A 5E50A 3VPYA 3T5PA 2KFUA 1J4KA 2A0TA 4G2SA 2AFFA 1GXCA 2XXSA 3UN0A 2P1RA 2BRFA 1R21A 1YJMA 1DEVA 2JGRA 2CSWA 4JIVD 4EJQA 2BONA 2FEZA 3PO8A 4JIWD 4EGXA 1MR1A 1U7VB 3A77A 5JEKA 1DD1A 2JKDA 1QWTA 3S40A 3GQSA 1U7FA 1K3JA 1WLNA 4WRRA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2JQJ A;  2JQI A;  1G3G A;  1K2N A;  3UMZ A;  2XT9 B;  2FF4 A;  3KT9 A;  3I6U A;  2KB3 A;  2JQL A;  3UNN A;  3HX1 A;  2KKL A;  1K2M A;  2PIE A;  4D9V A;  2W3O A;  2EH0 A;  3ELV A;  3FM8 A;  3I0M A;  1WV3 A;  3UNM A;  4A0E A;  1FHR A;  3POA A;  2G1L A;  1YJ5 C;  1FHQ A;  5DJO A;  1UHT A;  3MDB A;  3VA4 A;  3HUF A;  2JPE A;  1J4L A;  1J4P A;  5A8I A;  1LGP A;  3UV0 A;  1G6G A;  1DMZ A;  1QU5 A;  3I6W A;  2LC1 A;  3OUN A;  1J4O A;  1K3Q A;  3I0N A;  1MZK A;  4H87 A;  1K3N A;  1UJX A;  3ELS A;  2KB4 A;  3VA1 A;  4JON A;  3UOT A;  1J4Q A;  4QCJ A;  3HUE A;  1LGQ A;  5E50 A;  3VPY A;  2KFU A;  1J4K A;  2A0T A;  4G2S A;  2AFF A;  1GXC A;  3UN0 A;  2BRF A;  1R21 A;  1YJM A;  2CSW A;  4EJQ A;  2FEZ A;  3PO8 A;  4EGX A;  2JKD A;  3GQS A;  1K3J A;  1WLN A; 
#chains in the Genus database with same CATH topology
 3V8P A;  2JQJ A;  2JQI A;  4V24 A;  3V8N A;  2I29 A;  2I2D A;  5JEM A;  4KU0 D;  2I2B A;  5DHS A;  1KHU A;  3V8R A;  1G3G A;  5JEL A;  1K2N A;  4R9P A;  3UMZ A;  2XT9 B;  2FF4 A;  3KT9 A;  5JEJ A;  3I6U A;  2KB3 A;  4WER A;  2JQL A;  3UNN A;  1YGS A;  2QV7 A;  3HX1 A;  2KKL A;  1K2M A;  2PIE A;  4D9V A;  2W3O A;  2EH0 A;  3ELV A;  3FM8 A;  1U7F B;  3VZC A;  3I0M A;  3V8Q A;  5JEO A;  1WV3 A;  3UNM A;  4A0E A;  4HAO A;  1FHR A;  1ZOQ A;  2I1W A;  3POA A;  2G1L A;  1Z0U A;  2QVL A;  5DHU A;  1YJ5 C;  2I2C A;  1FHQ A;  5DJO A;  3VZD A;  1UHT A;  3MDB A;  3VA4 A;  1MJS A;  4A4Y A;  3HUF A;  3GMJ A;  5EJG A;  3V7W A;  5EJF A;  2I2A A;  2JPE A;  5DHQ A;  1J4L A;  1G88 A;  1YT5 A;  1KHX A;  1J4P A;  5A8I A;  2I2F A;  1LGP A;  5DHP A;  3UV0 A;  1G6G A;  3V7Y A;  1DMZ A;  1QU5 A;  5C4V A;  2LC1 A;  3I6W A;  5JER A;  3DIT A;  1MK2 A;  1Y3I A;  1J4O A;  3OUN A;  3I0N A;  1MZK A;  1U0R A;  4H87 A;  5DHT A;  1K3N A;  5BVI A;  1K3Q A;  1UJX A;  3ELS A;  3PFN A;  2KB4 A;  3VA1 A;  4JON A;  3V8M A;  3UOT A;  3VZB A;  3DSH A;  4DY6 A;  1J4Q A;  1J2F A;  1U7V A;  4QCJ A;  3HUE A;  1LGQ A;  5EJI A;  4L02 A;  5E50 A;  3VPY A;  3T5P A;  2KFU A;  1J4K A;  2A0T A;  4G2S A;  5DHR A;  2AFF A;  1GXC A;  2XXS A;  2AN1 A;  3UN0 A;  2P1R A;  2BRF A;  1R21 A;  2Q5F A;  1YJM A;  1DEV A;  1U0T A;  2JGR A;  3V80 A;  2CSW A;  4JIV D;  4EJQ A;  2BON A;  2FEZ A;  3PO8 A;  4JIW D;  4EGX A;  1MR1 A;  1Y3H A;  1SUW A;  3V7U A;  5EJH A;  1U7V B;  3A77 A;  1Z0Z A;  5JEK A;  1DD1 A;  2JKD A;  1QWT A;  3S40 A;  3GQS A;  1U7F A;  1K3J A;  1WLN A;  1Z0S A;  4WRR A;  3AFO A; 
#chains in the Genus database with same CATH homology
 2JQJ A;  2JQI A;  4V24 A;  5JEM A;  4KU0 D;  1KHU A;  1G3G A;  5JEL A;  1K2N A;  4R9P A;  3UMZ A;  2XT9 B;  2FF4 A;  3KT9 A;  5JEJ A;  3I6U A;  2KB3 A;  4WER A;  2JQL A;  3UNN A;  1YGS A;  2QV7 A;  3HX1 A;  2KKL A;  1K2M A;  2PIE A;  4D9V A;  2W3O A;  2EH0 A;  3ELV A;  3FM8 A;  1U7F B;  3VZC A;  3I0M A;  5JEO A;  1WV3 A;  3UNM A;  4A0E A;  1FHR A;  1ZOQ A;  3POA A;  2G1L A;  2QVL A;  1YJ5 C;  1FHQ A;  5DJO A;  3VZD A;  1UHT A;  3MDB A;  3VA4 A;  1MJS A;  4A4Y A;  3HUF A;  3GMJ A;  2JPE A;  1J4L A;  1G88 A;  1KHX A;  1J4P A;  5A8I A;  1LGP A;  3UV0 A;  1G6G A;  1DMZ A;  1QU5 A;  5C4V A;  3I6W A;  2LC1 A;  5JER A;  3DIT A;  1MK2 A;  3OUN A;  1J4O A;  1K3Q A;  3I0N A;  1MZK A;  4H87 A;  1K3N A;  5BVI A;  1UJX A;  3ELS A;  2KB4 A;  3VA1 A;  4JON A;  3UOT A;  3VZB A;  3DSH A;  1J4Q A;  1J2F A;  1U7V A;  4QCJ A;  3HUE A;  1LGQ A;  4L02 A;  5E50 A;  3VPY A;  3T5P A;  2KFU A;  1J4K A;  2A0T A;  4G2S A;  2AFF A;  1GXC A;  2XXS A;  3UN0 A;  2P1R A;  2BRF A;  1R21 A;  1YJM A;  1DEV A;  2JGR A;  2CSW A;  4JIV D;  4EJQ A;  2BON A;  2FEZ A;  3PO8 A;  4JIW D;  4EGX A;  1MR1 A;  1U7V B;  3A77 A;  5JEK A;  1DD1 A;  2JKD A;  1QWT A;  3S40 A;  3GQS A;  1U7F A;  1K3J A;  1WLN A;  4WRR A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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