1YJ5C

Molecular architecture of mammalian polynucleotide kinase, a dna repair enzyme
Total Genus 14
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
14
sequence length
105
structure length
105
Chain Sequence
SRGRLWLQSPTGGPPPIFLPSDGQALVLGRGPLTQVTDRKCSRNQVELIADPESRTVAVKQLGVNPSTVGVHELKPGLSGSLSLGDVLYLVNGLYPLTLRWEELS
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title The molecular architecture of the mammalian DNA repair enzyme, polynucleotide kinase.
pubmed doi rcsb
molecule tags Transferase
source organism Mus musculus
molecule keywords 5' polynucleotide kinase-3' phosphatase catalytic domain
total genus 14
structure length 105
sequence length 105
ec nomenclature ec 2.7.1.78: Polynucleotide 5'-hydroxyl-kinase.
pdb deposition date 2005-01-13

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
C PF17913 FHA_2 FHA domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.60.200.20 Mainly Beta Sandwich Tumour Suppressor Smad4 Tumour Suppressor Smad4 1yj5C00
1YJ5C 1G6GA 5A8IA 2LC1A 1LGPA 1YJMA 3POAA 2XT9B 1G3GA 1GXCA 2G1LA 2JKDA 1K3JA 3HUFA 3HX1A 3UMZA 1LGQA 3MDBA 1QU5A 2FEZA 4EGXA 3I6WA 4QCJA 1DMZA 1K3NA 2W3OA 3UNMA 3VA4A 2KFUA 3VPYA 2JQLA 3I6UA 2KB3A 1J4QA 4JONA 4G2SA 1WLNA 3I0MA 2A0TA 2KB4A 3UV0A 2FF4A 4H87A 2JPEA 3I0NA 2KKLA 3UOTA 1J4PA 2BRFA 1UJXA 1UHTA 3ELVA 3PO8A 3HUEA 3KT9A 1K2MA 4D9VA 1FHQA 2EH0A 5E50A 1FHRA 2CSWA 2JQIA 1K2NA 3UNNA 3OUNA 3FM8A 1J4OA 2JQJA 2PIEA 3VA1A 4EJQA 3ELSA 5DJOA 4A0EA 3UN0A 1J4LA 1K3QA 2AFFA 1MZKA 3GQSA 1J4KA 1WV3A 1R21A
chains in the Genus database with same CATH superfamily
1U7VA 4R9PA 3VZCA 3PFNA 5DHPA 2I29A 1MK2A 4JIVD 1YJ5C 5EJIA 1G6GA 1U7FA 5DHRA 5A8IA 2LC1A 2BONA 3GMJA 5JELA 1LGPA 1YJMA 3POAA 1KHUA 2XT9B 1MJSA 1U0RA 1G3GA 1QWTA 1SUWA 3V7UA 5DHUA 1GXCA 2G1LA 2JKDA 1K3JA 3HUFA 3HX1A 1G88A 3DSHA 3UMZA 2QVLA 1LGQA 1U0TA 3MDBA 1DEVA 1J2FA 2I2FA 3V8MA 2I2BA 1QU5A 2FEZA 4EGXA 3I6WA 1ZOQA 4QCJA 1DMZA 1K3NA 2W3OA 3UNMA 1YGSA 3VA4A 2I1WA 5EJHA 2KFUA 3VPYA 2JQLA 5JEJA 3I6UA 2KB3A 1J4QA 4JONA 4G2SA 1WLNA 1MR1A 2QV7A 3I0MA 2A0TA 2KB4A 5DHSA 1Z0ZA 3UV0A 4WERA 2FF4A 2XXSA 3VZBA 4H87A 3V8NA 2JPEA 3I0NA 2I2AA 2KKLA 3UOTA 1J4PA 1KHXA 1UJXA 2BRFA 3V8RA 4A4YA 1UHTA 2Q5FA 5JEMA 4JIWD 2AN1A 3ELVA 3PO8A 4L02A 2I2DA 5C4VA 3HUEA 3V80A 3KT9A 1K2MA 4D9VA 5JERA 3AFOA 3T5PA 4HAOA 2EH0A 1FHQA 5E50A 2P1RA 2CSWA 1FHRA 5DHTA 2JQIA 4WRRA 1K2NA 3UNNA 1U7VB 5BVIA 3OUNA 1Y3HA 3FM8A 3V7WA 1J4OA 3V8QA 2JQJA 2PIEA 3V8PA 3VA1A 4V24A 4EJQA 5JEKA 3ELSA 5EJFA 1U7FB 5DJOA 5JEOA 2I2CA 1YT5A 4A0EA 5DHQA 3UN0A 3V7YA 1J4LA 1K3QA 3S40A 1Y3IA 2AFFA 1MZKA 3A77A 3DITA 3VZDA 4DY6A 3GQSA 1J4KA 1WV3A 2JGRA 1R21A 1Z0UA 4KU0D 1Z0SA 1DD1A 5EJGA
chains in the Genus database with same CATH topology
1U7VA 4R9PA 3VZCA 1MK2A 1YJ5C 1G6GA 1U7FA 5A8IA 2LC1A 2BONA 3GMJA 5JELA 1LGPA 1YJMA 3POAA 1KHUA 2XT9B 1MJSA 1G3GA 1QWTA 1GXCA 2G1LA 2JKDA 1K3JA 3HX1A 3HUFA 1G88A 3DSHA 3UMZA 2QVLA 1LGQA 3MDBA 1DEVA 1J2FA 1QU5A 2FEZA 4EGXA 3I6WA 1ZOQA 4QCJA 1DMZA 1K3NA 2W3OA 3UNMA 1YGSA 3VA4A 2KFUA 3VPYA 2JQLA 5JEJA 3I6UA 2KB3A 1J4QA 4JONA 4G2SA 1WLNA 1MR1A 2QV7A 3I0MA 2A0TA 2KB4A 3UV0A 4WERA 2FF4A 2XXSA 3VZBA 4H87A 2JPEA 3I0NA 2KKLA 3UOTA 1J4PA 1KHXA 1UJXA 2BRFA 4A4YA 1UHTA 5JEMA 4JIWD 3ELVA 3PO8A 4L02A 5C4VA 3HUEA 3KT9A 1K2MA 4D9VA 5JERA 3T5PA 2EH0A 1FHQA 5E50A 2P1RA 2CSWA 1FHRA 2JQIA 4WRRA 1K2NA 3UNNA 1U7VB 5BVIA 3OUNA 3FM8A 1J4OA 2JQJA 2PIEA 3VA1A 4EJQA 4V24A 5JEKA 3ELSA 1U7FB 5DJOA 5JEOA 4A0EA 3UN0A 1J4LA 1K3QA 3S40A 2AFFA 1MZKA 3A77A 3DITA 3VZDA 3GQSA 1J4KA 1WV3A 2JGRA 1R21A 4KU0D 4JIVD 1DD1A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1YJ5 C;  1G6G A;  5A8I A;  2LC1 A;  1LGP A;  1YJM A;  3POA A;  2XT9 B;  1G3G A;  1GXC A;  2G1L A;  2JKD A;  1K3J A;  3HUF A;  3HX1 A;  3UMZ A;  1LGQ A;  3MDB A;  1QU5 A;  2FEZ A;  4EGX A;  3I6W A;  4QCJ A;  1DMZ A;  1K3N A;  2W3O A;  3UNM A;  3VA4 A;  2KFU A;  3VPY A;  2JQL A;  3I6U A;  2KB3 A;  1J4Q A;  4JON A;  4G2S A;  1WLN A;  3I0M A;  2A0T A;  2KB4 A;  3UV0 A;  2FF4 A;  4H87 A;  2JPE A;  3I0N A;  2KKL A;  3UOT A;  1J4P A;  2BRF A;  1UJX A;  1UHT A;  3ELV A;  3PO8 A;  3HUE A;  3KT9 A;  1K2M A;  4D9V A;  1FHQ A;  2EH0 A;  5E50 A;  1FHR A;  2CSW A;  2JQI A;  1K2N A;  3UNN A;  3OUN A;  3FM8 A;  1J4O A;  2JQJ A;  2PIE A;  3VA1 A;  4EJQ A;  3ELS A;  5DJO A;  4A0E A;  3UN0 A;  1J4L A;  1K3Q A;  2AFF A;  1MZK A;  3GQS A;  1J4K A;  1WV3 A;  1R21 A; 
#chains in the Genus database with same CATH topology
 1U7V A;  4R9P A;  3VZC A;  3PFN A;  5DHP A;  2I29 A;  1MK2 A;  4JIV D;  1YJ5 C;  5EJI A;  1G6G A;  1U7F A;  5DHR A;  5A8I A;  2LC1 A;  2BON A;  3GMJ A;  5JEL A;  1LGP A;  1YJM A;  3POA A;  1KHU A;  2XT9 B;  1MJS A;  1U0R A;  1G3G A;  1QWT A;  1SUW A;  3V7U A;  5DHU A;  1GXC A;  2G1L A;  2JKD A;  1K3J A;  3HUF A;  3HX1 A;  1G88 A;  3DSH A;  3UMZ A;  2QVL A;  1LGQ A;  1U0T A;  3MDB A;  1DEV A;  1J2F A;  2I2F A;  3V8M A;  2I2B A;  1QU5 A;  2FEZ A;  4EGX A;  3I6W A;  1ZOQ A;  4QCJ A;  1DMZ A;  1K3N A;  2W3O A;  3UNM A;  1YGS A;  3VA4 A;  2I1W A;  5EJH A;  2KFU A;  3VPY A;  2JQL A;  5JEJ A;  3I6U A;  2KB3 A;  1J4Q A;  4JON A;  4G2S A;  1WLN A;  1MR1 A;  2QV7 A;  3I0M A;  2A0T A;  2KB4 A;  5DHS A;  1Z0Z A;  3UV0 A;  4WER A;  2FF4 A;  2XXS A;  3VZB A;  4H87 A;  3V8N A;  2JPE A;  3I0N A;  2I2A A;  2KKL A;  3UOT A;  1J4P A;  1KHX A;  1UJX A;  2BRF A;  3V8R A;  4A4Y A;  1UHT A;  2Q5F A;  5JEM A;  4JIW D;  2AN1 A;  3ELV A;  3PO8 A;  4L02 A;  2I2D A;  5C4V A;  3HUE A;  3V80 A;  3KT9 A;  1K2M A;  4D9V A;  5JER A;  3AFO A;  3T5P A;  4HAO A;  2EH0 A;  1FHQ A;  5E50 A;  2P1R A;  2CSW A;  1FHR A;  5DHT A;  2JQI A;  4WRR A;  1K2N A;  3UNN A;  1U7V B;  5BVI A;  3OUN A;  1Y3H A;  3FM8 A;  3V7W A;  1J4O A;  3V8Q A;  2JQJ A;  2PIE A;  3V8P A;  3VA1 A;  4V24 A;  4EJQ A;  5JEK A;  3ELS A;  5EJF A;  1U7F B;  5DJO A;  5JEO A;  2I2C A;  1YT5 A;  4A0E A;  5DHQ A;  3UN0 A;  3V7Y A;  1J4L A;  1K3Q A;  3S40 A;  1Y3I A;  2AFF A;  1MZK A;  3A77 A;  3DIT A;  3VZD A;  4DY6 A;  3GQS A;  1J4K A;  1WV3 A;  2JGR A;  1R21 A;  1Z0U A;  4KU0 D;  1Z0S A;  1DD1 A;  5EJG A; 
#chains in the Genus database with same CATH homology
 1U7V A;  4R9P A;  3VZC A;  1MK2 A;  1YJ5 C;  1G6G A;  1U7F A;  5A8I A;  2LC1 A;  2BON A;  3GMJ A;  5JEL A;  1LGP A;  1YJM A;  3POA A;  1KHU A;  2XT9 B;  1MJS A;  1G3G A;  1QWT A;  1GXC A;  2G1L A;  2JKD A;  1K3J A;  3HX1 A;  3HUF A;  1G88 A;  3DSH A;  3UMZ A;  2QVL A;  1LGQ A;  3MDB A;  1DEV A;  1J2F A;  1QU5 A;  2FEZ A;  4EGX A;  3I6W A;  1ZOQ A;  4QCJ A;  1DMZ A;  1K3N A;  2W3O A;  3UNM A;  1YGS A;  3VA4 A;  2KFU A;  3VPY A;  2JQL A;  5JEJ A;  3I6U A;  2KB3 A;  1J4Q A;  4JON A;  4G2S A;  1WLN A;  1MR1 A;  2QV7 A;  3I0M A;  2A0T A;  2KB4 A;  3UV0 A;  4WER A;  2FF4 A;  2XXS A;  3VZB A;  4H87 A;  2JPE A;  3I0N A;  2KKL A;  3UOT A;  1J4P A;  1KHX A;  1UJX A;  2BRF A;  4A4Y A;  1UHT A;  5JEM A;  4JIW D;  3ELV A;  3PO8 A;  4L02 A;  5C4V A;  3HUE A;  3KT9 A;  1K2M A;  4D9V A;  5JER A;  3T5P A;  2EH0 A;  1FHQ A;  5E50 A;  2P1R A;  2CSW A;  1FHR A;  2JQI A;  4WRR A;  1K2N A;  3UNN A;  1U7V B;  5BVI A;  3OUN A;  3FM8 A;  1J4O A;  2JQJ A;  2PIE A;  3VA1 A;  4EJQ A;  4V24 A;  5JEK A;  3ELS A;  1U7F B;  5DJO A;  5JEO A;  4A0E A;  3UN0 A;  1J4L A;  1K3Q A;  3S40 A;  2AFF A;  1MZK A;  3A77 A;  3DIT A;  3VZD A;  3GQS A;  1J4K A;  1WV3 A;  2JGR A;  1R21 A;  4KU0 D;  4JIV D;  1DD1 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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