1FHQA

Refined solution structure of the fha2 domain of rad53
Total Genus 24
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
24
sequence length
158
structure length
158
Chain Sequence
GNGRFLTLKPLPDSIIQESLEIQQGVNPFFIGRSEDCNCKIEDNRLSRVHCFIFKKRHAVGKSMYESPAQGLDDIWYCHTGTNVSYLNNNRMIQGTKFLLQDGDEIKIIWDKNNKFVIGFKVEINDTTGLFNEGLGMLQEQRVVLKQTAEEKDLVKKL
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title II. Structure and specificity of the interaction between the FHA2 domain of Rad53 and phosphotyrosyl peptides.
pubmed doi rcsb
molecule tags Transferase
source organism Saccharomyces cerevisiae
molecule keywords PROTEIN KINASE SPK1
total genus 24
structure length 158
sequence length 158
ec nomenclature ec 2.7.12.1: Dual-specificity kinase.
pdb deposition date 2000-08-02

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00498 FHA FHA domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.60.200.20 Mainly Beta Sandwich Tumour Suppressor Smad4 Tumour Suppressor Smad4 1fhqA00
2AFFA 3UOTA 2CSWA 3I0MA 1K3JA 3KT9A 5E50A 2BRFA 2JKDA 3GQSA 3FM8A 2KKLA 1GXCA 2KB3A 1FHRA 3I6UA 2W3OA 2A0TA 1YJMA 3I0NA 3VPYA 1J4OA 1K2NA 2G1LA 3VA4A 5A8IA 1J4PA 3ELVA 2EH0A 4EGXA 2FF4A 3HX1A 4A0EA 1G6GA 4G2SA 3OUNA 4EJQA 2KFUA 3PO8A 1J4LA 2LC1A 3UV0A 3UMZA 3UN0A 1K3NA 2XT9B 1QU5A 3HUFA 4H87A 1J4KA 1J4QA 3VA1A 3ELSA 2PIEA 1K3QA 1UHTA 1WLNA 1YJ5C 4JONA 3POAA 5DJOA 3I6WA 1DMZA 1WV3A 4D9VA 1G3GA 2JQJA 2KB4A 2JQLA 1K2MA 1R21A 3UNMA 3UNNA 1FHQA 4QCJA 2FEZA 1UJXA 1LGQA 2JQIA 2JPEA 1MZKA 3MDBA 3HUEA 1LGPA
chains in the Genus database with same CATH superfamily
2AFFA 3UOTA 3GMJA 2CSWA 5DHTA 3VZCA 1KHXA 2I2DA 3I0MA 1Z0UA 3V7YA 4JIWD 1K3JA 1U7VA 3KT9A 5E50A 2BRFA 3VZBA 2JKDA 3GQSA 3FM8A 1Z0SA 1Y3HA 5DHUA 3VZDA 2KKLA 5JEOA 5BVIA 1J2FA 1MK2A 1GXCA 2KB3A 1FHRA 3I6UA 2W3OA 1DD1A 3V7WA 1YGSA 2I2FA 2P1RA 5DHSA 2A0TA 3V7UA 3V8RA 1KHUA 1G88A 1YJMA 2QV7A 3I0NA 1YT5A 3VPYA 1J4OA 1K2NA 2G1LA 4A4YA 3VA4A 5A8IA 1J4PA 3ELVA 2EH0A 5JERA 2I1WA 3S40A 2XXSA 5EJHA 2I2CA 5EJIA 4EGXA 2JGRA 3V8PA 2FF4A 3HX1A 5JEKA 4A0EA 3DITA 1G6GA 4G2SA 2I29A 3OUNA 4EJQA 1Z0ZA 3PFNA 1ZOQA 2KFUA 3PO8A 1Y3IA 1J4LA 2LC1A 3UN0A 3UMZA 3UV0A 3DSHA 4JIVD 1K3NA 2XT9B 4L02A 1QU5A 4DY6A 3HUFA 5C4VA 1QWTA 2Q5FA 5DHRA 4H87A 1J4KA 1J4QA 5EJGA 3VA1A 3T5PA 5JEJA 1U7FB 3ELSA 4WERA 3V80A 3V8QA 2PIEA 1K3QA 1UHTA 1WLNA 1YJ5C 3AFOA 4JONA 3POAA 5DHQA 4R9PA 1MR1A 5DJOA 3I6WA 3V8NA 1U0RA 1DMZA 3V8MA 1WV3A 4D9VA 1G3GA 2JQJA 4KU0D 2QVLA 2KB4A 2JQLA 4V24A 1MJSA 1SUWA 1U0TA 2BONA 5JELA 2AN1A 5EJFA 1K2MA 5JEMA 3A77A 1R21A 1U7FA 3UNMA 3UNNA 1FHQA 4HAOA 1DEVA 4QCJA 2I2BA 1U7VB 2FEZA 1UJXA 4WRRA 1LGQA 2JQIA 2JPEA 1MZKA 3MDBA 5DHPA 2I2AA 3HUEA 1LGPA
chains in the Genus database with same CATH topology
2AFFA 3UOTA 3GMJA 2CSWA 3VZCA 1KHXA 3I0MA 4JIWD 1K3JA 1U7VA 3KT9A 5E50A 2BRFA 3VZBA 2JKDA 3GQSA 3FM8A 3VZDA 5JEOA 2KKLA 5BVIA 1J2FA 1MK2A 1GXCA 2KB3A 1FHRA 3I6UA 2W3OA 1DD1A 1YGSA 2P1RA 2A0TA 1KHUA 1G88A 1YJMA 2QV7A 3I0NA 3VPYA 1J4OA 1K2NA 2G1LA 4A4YA 3VA4A 5A8IA 1J4PA 3ELVA 2EH0A 5JERA 3S40A 2XXSA 4EGXA 2JGRA 2FF4A 3HX1A 5JEKA 4A0EA 3DITA 1G6GA 4G2SA 3OUNA 4EJQA 1ZOQA 2KFUA 3PO8A 1J4LA 2LC1A 3UN0A 3UMZA 3UV0A 3DSHA 4JIVD 1K3NA 2XT9B 4L02A 1QU5A 3HUFA 5C4VA 1QWTA 4H87A 1J4KA 1J4QA 3VA1A 3T5PA 5JEJA 1U7FB 3ELSA 4WERA 2PIEA 1K3QA 1UHTA 1WLNA 1YJ5C 4JONA 3POAA 4R9PA 1MR1A 5DJOA 3I6WA 1DMZA 1WV3A 4D9VA 1G3GA 2JQJA 4KU0D 2QVLA 2KB4A 2JQLA 4V24A 1MJSA 2BONA 5JELA 1K2MA 5JEMA 3A77A 1R21A 1U7FA 3UNMA 3UNNA 1FHQA 1DEVA 4QCJA 1U7VB 2FEZA 1UJXA 4WRRA 1LGQA 2JQIA 2JPEA 1MZKA 3MDBA 3HUEA 1LGPA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2AFF A;  3UOT A;  2CSW A;  3I0M A;  1K3J A;  3KT9 A;  5E50 A;  2BRF A;  2JKD A;  3GQS A;  3FM8 A;  2KKL A;  1GXC A;  2KB3 A;  1FHR A;  3I6U A;  2W3O A;  2A0T A;  1YJM A;  3I0N A;  3VPY A;  1J4O A;  1K2N A;  2G1L A;  3VA4 A;  5A8I A;  1J4P A;  3ELV A;  2EH0 A;  4EGX A;  2FF4 A;  3HX1 A;  4A0E A;  1G6G A;  4G2S A;  3OUN A;  4EJQ A;  2KFU A;  3PO8 A;  1J4L A;  2LC1 A;  3UV0 A;  3UMZ A;  3UN0 A;  1K3N A;  2XT9 B;  1QU5 A;  3HUF A;  4H87 A;  1J4K A;  1J4Q A;  3VA1 A;  3ELS A;  2PIE A;  1K3Q A;  1UHT A;  1WLN A;  1YJ5 C;  4JON A;  3POA A;  5DJO A;  3I6W A;  1DMZ A;  1WV3 A;  4D9V A;  1G3G A;  2JQJ A;  2KB4 A;  2JQL A;  1K2M A;  1R21 A;  3UNM A;  3UNN A;  1FHQ A;  4QCJ A;  2FEZ A;  1UJX A;  1LGQ A;  2JQI A;  2JPE A;  1MZK A;  3MDB A;  3HUE A;  1LGP A; 
#chains in the Genus database with same CATH topology
 2AFF A;  3UOT A;  3GMJ A;  2CSW A;  5DHT A;  3VZC A;  1KHX A;  2I2D A;  3I0M A;  1Z0U A;  3V7Y A;  4JIW D;  1K3J A;  1U7V A;  3KT9 A;  5E50 A;  2BRF A;  3VZB A;  2JKD A;  3GQS A;  3FM8 A;  1Z0S A;  1Y3H A;  5DHU A;  3VZD A;  2KKL A;  5JEO A;  5BVI A;  1J2F A;  1MK2 A;  1GXC A;  2KB3 A;  1FHR A;  3I6U A;  2W3O A;  1DD1 A;  3V7W A;  1YGS A;  2I2F A;  2P1R A;  5DHS A;  2A0T A;  3V7U A;  3V8R A;  1KHU A;  1G88 A;  1YJM A;  2QV7 A;  3I0N A;  1YT5 A;  3VPY A;  1J4O A;  1K2N A;  2G1L A;  4A4Y A;  3VA4 A;  5A8I A;  1J4P A;  3ELV A;  2EH0 A;  5JER A;  2I1W A;  3S40 A;  2XXS A;  5EJH A;  2I2C A;  5EJI A;  4EGX A;  2JGR A;  3V8P A;  2FF4 A;  3HX1 A;  5JEK A;  4A0E A;  3DIT A;  1G6G A;  4G2S A;  2I29 A;  3OUN A;  4EJQ A;  1Z0Z A;  3PFN A;  1ZOQ A;  2KFU A;  3PO8 A;  1Y3I A;  1J4L A;  2LC1 A;  3UN0 A;  3UMZ A;  3UV0 A;  3DSH A;  4JIV D;  1K3N A;  2XT9 B;  4L02 A;  1QU5 A;  4DY6 A;  3HUF A;  5C4V A;  1QWT A;  2Q5F A;  5DHR A;  4H87 A;  1J4K A;  1J4Q A;  5EJG A;  3VA1 A;  3T5P A;  5JEJ A;  1U7F B;  3ELS A;  4WER A;  3V80 A;  3V8Q A;  2PIE A;  1K3Q A;  1UHT A;  1WLN A;  1YJ5 C;  3AFO A;  4JON A;  3POA A;  5DHQ A;  4R9P A;  1MR1 A;  5DJO A;  3I6W A;  3V8N A;  1U0R A;  1DMZ A;  3V8M A;  1WV3 A;  4D9V A;  1G3G A;  2JQJ A;  4KU0 D;  2QVL A;  2KB4 A;  2JQL A;  4V24 A;  1MJS A;  1SUW A;  1U0T A;  2BON A;  5JEL A;  2AN1 A;  5EJF A;  1K2M A;  5JEM A;  3A77 A;  1R21 A;  1U7F A;  3UNM A;  3UNN A;  1FHQ A;  4HAO A;  1DEV A;  4QCJ A;  2I2B A;  1U7V B;  2FEZ A;  1UJX A;  4WRR A;  1LGQ A;  2JQI A;  2JPE A;  1MZK A;  3MDB A;  5DHP A;  2I2A A;  3HUE A;  1LGP A; 
#chains in the Genus database with same CATH homology
 2AFF A;  3UOT A;  3GMJ A;  2CSW A;  3VZC A;  1KHX A;  3I0M A;  4JIW D;  1K3J A;  1U7V A;  3KT9 A;  5E50 A;  2BRF A;  3VZB A;  2JKD A;  3GQS A;  3FM8 A;  3VZD A;  5JEO A;  2KKL A;  5BVI A;  1J2F A;  1MK2 A;  1GXC A;  2KB3 A;  1FHR A;  3I6U A;  2W3O A;  1DD1 A;  1YGS A;  2P1R A;  2A0T A;  1KHU A;  1G88 A;  1YJM A;  2QV7 A;  3I0N A;  3VPY A;  1J4O A;  1K2N A;  2G1L A;  4A4Y A;  3VA4 A;  5A8I A;  1J4P A;  3ELV A;  2EH0 A;  5JER A;  3S40 A;  2XXS A;  4EGX A;  2JGR A;  2FF4 A;  3HX1 A;  5JEK A;  4A0E A;  3DIT A;  1G6G A;  4G2S A;  3OUN A;  4EJQ A;  1ZOQ A;  2KFU A;  3PO8 A;  1J4L A;  2LC1 A;  3UN0 A;  3UMZ A;  3UV0 A;  3DSH A;  4JIV D;  1K3N A;  2XT9 B;  4L02 A;  1QU5 A;  3HUF A;  5C4V A;  1QWT A;  4H87 A;  1J4K A;  1J4Q A;  3VA1 A;  3T5P A;  5JEJ A;  1U7F B;  3ELS A;  4WER A;  2PIE A;  1K3Q A;  1UHT A;  1WLN A;  1YJ5 C;  4JON A;  3POA A;  4R9P A;  1MR1 A;  5DJO A;  3I6W A;  1DMZ A;  1WV3 A;  4D9V A;  1G3G A;  2JQJ A;  4KU0 D;  2QVL A;  2KB4 A;  2JQL A;  4V24 A;  1MJS A;  2BON A;  5JEL A;  1K2M A;  5JEM A;  3A77 A;  1R21 A;  1U7F A;  3UNM A;  3UNN A;  1FHQ A;  1DEV A;  4QCJ A;  1U7V B;  2FEZ A;  1UJX A;  4WRR A;  1LGQ A;  2JQI A;  2JPE A;  1MZK A;  3MDB A;  3HUE A;  1LGP A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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