1FHRA

Solution structure of the fha2 domain of rad53 complexed with a phosphotyrosyl peptide
Total Genus 21
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
21
sequence length
158
structure length
158
Chain Sequence
GNGRFLTLKPLPDSIIQESLEIQQGVNPFFIGRSEDCNCKIEDNRLSRVHCFIFKKRHAVGKSMYESPAQGLDDIWYCHTGTNVSYLNNNRMIQGTKFLLQDGDEIKIIWDKNNKFVIGFKVEINDTTGLFNEGLGMLQEQRVVLKQTAEEKDLVKKL
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title II. Structure and specificity of the interaction between the FHA2 domain of Rad53 and phosphotyrosyl peptides.
pubmed doi rcsb
molecule tags Transferase
source organism Saccharomyces cerevisiae
molecule keywords PROTEIN KINASE SPK1
total genus 21
structure length 158
sequence length 158
ec nomenclature ec 2.7.12.1: Dual-specificity kinase.
pdb deposition date 2000-08-02

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00498 FHA FHA domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.60.200.20 Mainly Beta Sandwich Tumour Suppressor Smad4 Tumour Suppressor Smad4 1fhrA00
3KT9A 4G2SA 2FF4A 3PO8A 3VA1A 3POAA 3I6WA 1K2MA 4H87A 3ELSA 3HX1A 1R21A 1UHTA 3MDBA 1G6GA 1K3NA 2JQJA 1LGPA 1K2NA 2XT9B 5E50A 2CSWA 4A0EA 1FHRA 1K3JA 1J4OA 3GQSA 3UMZA 2KKLA 3FM8A 1J4LA 1J4PA 1YJMA 2KFUA 1G3GA 1DMZA 1UJXA 2JQIA 4EJQA 5DJOA 1GXCA 2JPEA 2BRFA 3I0NA 4EGXA 4JONA 3ELVA 3HUFA 3I6UA 2G1LA 2PIEA 1J4KA 3UNNA 2A0TA 1QU5A 2JKDA 3UV0A 3UNMA 2JQLA 3I0MA 3UN0A 2KB3A 2FEZA 1J4QA 1WLNA 1LGQA 3VPYA 2LC1A 4D9VA 1MZKA 2W3OA 3OUNA 2KB4A 5A8IA 4QCJA 2AFFA 3HUEA 1FHQA 1K3QA 2EH0A 1YJ5C 1WV3A 3VA4A 3UOTA
chains in the Genus database with same CATH superfamily
2I2DA 4JIVD 5C4VA 2I2FA 3KT9A 3VZDA 4G2SA 2I2BA 1QWTA 2QV7A 5EJIA 2FF4A 5DHTA 1YGSA 3PO8A 3VA1A 3POAA 1Y3HA 3I6WA 1K2MA 3A77A 5EJFA 4H87A 2I2AA 4L02A 3ELSA 3HX1A 1ZOQA 1R21A 1UHTA 1Z0SA 3MDBA 5DHSA 1SUWA 1G6GA 1K3NA 3V8PA 2JQJA 1LGPA 5JEMA 1K2NA 2XT9B 1KHUA 5JEKA 3S40A 5E50A 5JEOA 4DY6A 2CSWA 4A0EA 1FHRA 1K3JA 1J4OA 1MK2A 3GQSA 5DHUA 3UMZA 2KKLA 3FM8A 3V7WA 1J4LA 1J4PA 4R9PA 1G88A 3V7UA 1YJMA 3AFOA 2XXSA 2KFUA 4KU0D 1U7FB 1G3GA 2BONA 3V7YA 3DSHA 1YT5A 1U0RA 1DMZA 1UJXA 2JQIA 4EJQA 5JELA 1U0TA 2I29A 5DJOA 1GXCA 2JPEA 2BRFA 1Z0ZA 3ELVA 3I0NA 4JONA 5EJHA 4EGXA 3T5PA 2I2CA 2Q5FA 3DITA 5DHQA 3VZCA 3HUFA 2JGRA 3I6UA 1U7FA 2G1LA 2PIEA 1J4KA 4A4YA 3UNNA 5EJGA 2P1RA 5JERA 2A0TA 1QU5A 2JKDA 4JIWD 1DEVA 5BVIA 2AN1A 3UV0A 3UNMA 3V8RA 2JQLA 1J2FA 3I0MA 2I1WA 3UN0A 4WERA 2KB3A 2FEZA 4WRRA 1J4QA 4HAOA 1DD1A 1WLNA 1LGQA 3VPYA 2LC1A 4D9VA 1Y3IA 1MZKA 3V8NA 5DHPA 1MJSA 3PFNA 2W3OA 3GMJA 3OUNA 3V80A 2KB4A 1U7VA 3V8MA 3V8QA 5A8IA 4QCJA 1Z0UA 2AFFA 3HUEA 1FHQA 1K3QA 2EH0A 2QVLA 1YJ5C 4V24A 1WV3A 3VZBA 5JEJA 5DHRA 3VA4A 1KHXA 1U7VB 1MR1A 3UOTA
chains in the Genus database with same CATH topology
4JIVD 5C4VA 3KT9A 3VZDA 4G2SA 1QWTA 2QV7A 2FF4A 1YGSA 3PO8A 3VA1A 3POAA 3I6WA 1K2MA 3A77A 4H87A 4L02A 3ELSA 3HX1A 1ZOQA 1R21A 1UHTA 3MDBA 1G6GA 1K3NA 2JQJA 1LGPA 5JEMA 1K2NA 2XT9B 1KHUA 5JEKA 3S40A 5E50A 5JEOA 2CSWA 4A0EA 1FHRA 1K3JA 1J4OA 1MK2A 3GQSA 3UMZA 2KKLA 3FM8A 1J4LA 1J4PA 4R9PA 1G88A 1YJMA 2XXSA 2KFUA 4KU0D 1U7FB 1G3GA 2BONA 3DSHA 1DMZA 1UJXA 2JQIA 4EJQA 5JELA 5DJOA 1GXCA 2JPEA 2BRFA 3T5PA 3I0NA 3ELVA 4JONA 4EGXA 3DITA 3VZCA 3HUFA 2JGRA 3I6UA 1U7FA 2G1LA 2PIEA 1J4KA 4A4YA 3UNNA 2P1RA 5JERA 2A0TA 1QU5A 2JKDA 4JIWD 1DEVA 5BVIA 3UV0A 3UNMA 2JQLA 1J2FA 3I0MA 3UN0A 4WERA 2KB3A 2FEZA 4WRRA 1J4QA 1DD1A 1WLNA 1LGQA 3VPYA 2LC1A 4D9VA 1MZKA 1MJSA 2W3OA 3GMJA 3OUNA 2KB4A 1U7VA 5A8IA 4QCJA 2AFFA 3HUEA 1FHQA 1K3QA 2EH0A 2QVLA 1YJ5C 4V24A 1WV3A 3VZBA 5JEJA 3VA4A 1KHXA 1U7VB 1MR1A 3UOTA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3KT9 A;  4G2S A;  2FF4 A;  3PO8 A;  3VA1 A;  3POA A;  3I6W A;  1K2M A;  4H87 A;  3ELS A;  3HX1 A;  1R21 A;  1UHT A;  3MDB A;  1G6G A;  1K3N A;  2JQJ A;  1LGP A;  1K2N A;  2XT9 B;  5E50 A;  2CSW A;  4A0E A;  1FHR A;  1K3J A;  1J4O A;  3GQS A;  3UMZ A;  2KKL A;  3FM8 A;  1J4L A;  1J4P A;  1YJM A;  2KFU A;  1G3G A;  1DMZ A;  1UJX A;  2JQI A;  4EJQ A;  5DJO A;  1GXC A;  2JPE A;  2BRF A;  3I0N A;  4EGX A;  4JON A;  3ELV A;  3HUF A;  3I6U A;  2G1L A;  2PIE A;  1J4K A;  3UNN A;  2A0T A;  1QU5 A;  2JKD A;  3UV0 A;  3UNM A;  2JQL A;  3I0M A;  3UN0 A;  2KB3 A;  2FEZ A;  1J4Q A;  1WLN A;  1LGQ A;  3VPY A;  2LC1 A;  4D9V A;  1MZK A;  2W3O A;  3OUN A;  2KB4 A;  5A8I A;  4QCJ A;  2AFF A;  3HUE A;  1FHQ A;  1K3Q A;  2EH0 A;  1YJ5 C;  1WV3 A;  3VA4 A;  3UOT A; 
#chains in the Genus database with same CATH topology
 2I2D A;  4JIV D;  5C4V A;  2I2F A;  3KT9 A;  3VZD A;  4G2S A;  2I2B A;  1QWT A;  2QV7 A;  5EJI A;  2FF4 A;  5DHT A;  1YGS A;  3PO8 A;  3VA1 A;  3POA A;  1Y3H A;  3I6W A;  1K2M A;  3A77 A;  5EJF A;  4H87 A;  2I2A A;  4L02 A;  3ELS A;  3HX1 A;  1ZOQ A;  1R21 A;  1UHT A;  1Z0S A;  3MDB A;  5DHS A;  1SUW A;  1G6G A;  1K3N A;  3V8P A;  2JQJ A;  1LGP A;  5JEM A;  1K2N A;  2XT9 B;  1KHU A;  5JEK A;  3S40 A;  5E50 A;  5JEO A;  4DY6 A;  2CSW A;  4A0E A;  1FHR A;  1K3J A;  1J4O A;  1MK2 A;  3GQS A;  5DHU A;  3UMZ A;  2KKL A;  3FM8 A;  3V7W A;  1J4L A;  1J4P A;  4R9P A;  1G88 A;  3V7U A;  1YJM A;  3AFO A;  2XXS A;  2KFU A;  4KU0 D;  1U7F B;  1G3G A;  2BON A;  3V7Y A;  3DSH A;  1YT5 A;  1U0R A;  1DMZ A;  1UJX A;  2JQI A;  4EJQ A;  5JEL A;  1U0T A;  2I29 A;  5DJO A;  1GXC A;  2JPE A;  2BRF A;  1Z0Z A;  3ELV A;  3I0N A;  4JON A;  5EJH A;  4EGX A;  3T5P A;  2I2C A;  2Q5F A;  3DIT A;  5DHQ A;  3VZC A;  3HUF A;  2JGR A;  3I6U A;  1U7F A;  2G1L A;  2PIE A;  1J4K A;  4A4Y A;  3UNN A;  5EJG A;  2P1R A;  5JER A;  2A0T A;  1QU5 A;  2JKD A;  4JIW D;  1DEV A;  5BVI A;  2AN1 A;  3UV0 A;  3UNM A;  3V8R A;  2JQL A;  1J2F A;  3I0M A;  2I1W A;  3UN0 A;  4WER A;  2KB3 A;  2FEZ A;  4WRR A;  1J4Q A;  4HAO A;  1DD1 A;  1WLN A;  1LGQ A;  3VPY A;  2LC1 A;  4D9V A;  1Y3I A;  1MZK A;  3V8N A;  5DHP A;  1MJS A;  3PFN A;  2W3O A;  3GMJ A;  3OUN A;  3V80 A;  2KB4 A;  1U7V A;  3V8M A;  3V8Q A;  5A8I A;  4QCJ A;  1Z0U A;  2AFF A;  3HUE A;  1FHQ A;  1K3Q A;  2EH0 A;  2QVL A;  1YJ5 C;  4V24 A;  1WV3 A;  3VZB A;  5JEJ A;  5DHR A;  3VA4 A;  1KHX A;  1U7V B;  1MR1 A;  3UOT A; 
#chains in the Genus database with same CATH homology
 4JIV D;  5C4V A;  3KT9 A;  3VZD A;  4G2S A;  1QWT A;  2QV7 A;  2FF4 A;  1YGS A;  3PO8 A;  3VA1 A;  3POA A;  3I6W A;  1K2M A;  3A77 A;  4H87 A;  4L02 A;  3ELS A;  3HX1 A;  1ZOQ A;  1R21 A;  1UHT A;  3MDB A;  1G6G A;  1K3N A;  2JQJ A;  1LGP A;  5JEM A;  1K2N A;  2XT9 B;  1KHU A;  5JEK A;  3S40 A;  5E50 A;  5JEO A;  2CSW A;  4A0E A;  1FHR A;  1K3J A;  1J4O A;  1MK2 A;  3GQS A;  3UMZ A;  2KKL A;  3FM8 A;  1J4L A;  1J4P A;  4R9P A;  1G88 A;  1YJM A;  2XXS A;  2KFU A;  4KU0 D;  1U7F B;  1G3G A;  2BON A;  3DSH A;  1DMZ A;  1UJX A;  2JQI A;  4EJQ A;  5JEL A;  5DJO A;  1GXC A;  2JPE A;  2BRF A;  3T5P A;  3I0N A;  3ELV A;  4JON A;  4EGX A;  3DIT A;  3VZC A;  3HUF A;  2JGR A;  3I6U A;  1U7F A;  2G1L A;  2PIE A;  1J4K A;  4A4Y A;  3UNN A;  2P1R A;  5JER A;  2A0T A;  1QU5 A;  2JKD A;  4JIW D;  1DEV A;  5BVI A;  3UV0 A;  3UNM A;  2JQL A;  1J2F A;  3I0M A;  3UN0 A;  4WER A;  2KB3 A;  2FEZ A;  4WRR A;  1J4Q A;  1DD1 A;  1WLN A;  1LGQ A;  3VPY A;  2LC1 A;  4D9V A;  1MZK A;  1MJS A;  2W3O A;  3GMJ A;  3OUN A;  2KB4 A;  1U7V A;  5A8I A;  4QCJ A;  2AFF A;  3HUE A;  1FHQ A;  1K3Q A;  2EH0 A;  2QVL A;  1YJ5 C;  4V24 A;  1WV3 A;  3VZB A;  5JEJ A;  3VA4 A;  1KHX A;  1U7V B;  1MR1 A;  3UOT A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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