1FHRA

Solution structure of the fha2 domain of rad53 complexed with a phosphotyrosyl peptide
Total Genus 21
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
21
sequence length
158
structure length
158
Chain Sequence
GNGRFLTLKPLPDSIIQESLEIQQGVNPFFIGRSEDCNCKIEDNRLSRVHCFIFKKRHAVGKSMYESPAQGLDDIWYCHTGTNVSYLNNNRMIQGTKFLLQDGDEIKIIWDKNNKFVIGFKVEINDTTGLFNEGLGMLQEQRVVLKQTAEEKDLVKKL
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title II. Structure and specificity of the interaction between the FHA2 domain of Rad53 and phosphotyrosyl peptides.
pubmed doi rcsb
molecule tags Transferase
source organism Saccharomyces cerevisiae
molecule keywords PROTEIN KINASE SPK1
total genus 21
structure length 158
sequence length 158
ec nomenclature ec 2.7.12.1: Dual-specificity kinase.
pdb deposition date 2000-08-02

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00498 FHA FHA domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.60.200.20 Mainly Beta Sandwich Tumour Suppressor Smad4 Tumour Suppressor Smad4 1fhrA00
3POAA 1J4KA 3I6UA 2BRFA 1FHQA 3I0MA 2JQLA 3HUFA 4H87A 2KKLA 2JKDA 4JONA 2AFFA 2JQIA 4EJQA 2W3OA 1UJXA 3VA1A 2JPEA 2FF4A 3UV0A 1LGPA 1GXCA 2CSWA 3UOTA 4D9VA 3HX1A 1UHTA 2KB3A 3UMZA 2PIEA 3UNMA 3I0NA 1J4OA 3MDBA 1YJ5C 3GQSA 2A0TA 1G6GA 1WLNA 1FHRA 3PO8A 3FM8A 2EH0A 3KT9A 5DJOA 4EGXA 1J4QA 5E50A 1YJMA 2LC1A 3ELVA 2XT9B 2KFUA 1LGQA 5A8IA 1K3JA 2FEZA 1K3QA 3OUNA 4QCJA 3UN0A 3VPYA 1J4PA 3UNNA 2KB4A 4G2SA 1R21A 1WV3A 3I6WA 1K2MA 1G3GA 1MZKA 1J4LA 1K2NA 2G1LA 3HUEA 1K3NA 1DMZA 1QU5A 2JQJA 3VA4A 3ELSA 4A0EA
chains in the Genus database with same CATH superfamily
3POAA 1J4KA 3V8RA 3I6UA 2I1WA 2AN1A 2BRFA 1FHQA 3V7YA 4A4YA 1Y3HA 3I0MA 2XXSA 2JQLA 1U0RA 3VZDA 1Z0SA 3HUFA 3V8PA 1G88A 4H87A 3V8MA 2KKLA 3DITA 3T5PA 2JKDA 4JONA 2AFFA 2JQIA 4EJQA 5JERA 2W3OA 5C4VA 1UJXA 3VA1A 2JPEA 2FF4A 1Z0UA 1LGPA 3UV0A 5JELA 5JEJA 4JIWD 1GXCA 3ELSA 2QVLA 5EJGA 2I2AA 4JIVD 2CSWA 3UOTA 4D9VA 3VZCA 3HX1A 1UHTA 1U7FB 5JEOA 2QV7A 2KB3A 3UMZA 2PIEA 3V7WA 3AFOA 3UNMA 2I2BA 3I0NA 1J4OA 3MDBA 1YGSA 1YJ5C 3GQSA 2A0TA 3V8QA 1G6GA 1WLNA 3VZBA 3V7UA 1MJSA 1FHRA 4KU0D 3PO8A 3FM8A 1U0TA 2EH0A 3KT9A 2I29A 5EJHA 3S40A 5DJOA 4EGXA 1U7VB 1J4QA 1KHUA 5DHPA 4R9PA 5EJIA 2I2CA 5E50A 1YJMA 1MR1A 2LC1A 1DEVA 1Z0ZA 3ELVA 2XT9B 1SUWA 2KFUA 3V8NA 1LGQA 4HAOA 5A8IA 5DHUA 1YT5A 3GMJA 1K3JA 1Y3IA 5JEMA 5BVIA 2FEZA 1K3QA 1DD1A 5DHRA 5JEKA 5DHQA 2I2DA 3OUNA 4V24A 1U7FA 4QCJA 1MK2A 3UN0A 3VPYA 1J4PA 2JGRA 3UNNA 1KHXA 2I2FA 1J2FA 5DHSA 4WERA 2KB4A 3PFNA 4G2SA 5DHTA 1R21A 4DY6A 1WV3A 3I6WA 2Q5FA 1U7VA 1K2MA 1G3GA 5EJFA 1MZKA 1J4LA 3A77A 1K2NA 2G1LA 3V80A 4L02A 3HUEA 1K3NA 1DMZA 1QU5A 2BONA 2JQJA 3VA4A 1QWTA 3DSHA 4WRRA 2P1RA 1ZOQA 4A0EA
chains in the Genus database with same CATH topology
3POAA 1J4KA 3I6UA 2BRFA 1FHQA 4A4YA 3I0MA 2XXSA 2JQLA 3VZDA 3HUFA 1G88A 4H87A 2KKLA 3DITA 3T5PA 2JKDA 4JONA 2AFFA 2JQIA 4EJQA 5JERA 2W3OA 5C4VA 1UJXA 3VA1A 2JPEA 2FF4A 3UV0A 1LGPA 5JELA 5JEJA 4JIWD 1GXCA 2QVLA 4JIVD 2CSWA 3UOTA 4D9VA 3VZCA 3HX1A 1UHTA 1U7FB 5JEOA 2QV7A 2KB3A 3UMZA 2PIEA 3UNMA 3I0NA 1J4OA 3MDBA 1YGSA 1YJ5C 2P1RA 3GQSA 2A0TA 1G6GA 1WLNA 3VZBA 1MJSA 1FHRA 4KU0D 3PO8A 3FM8A 2EH0A 3KT9A 3S40A 5DJOA 4EGXA 1U7VB 1J4QA 1KHUA 4R9PA 5E50A 1YJMA 1MR1A 2LC1A 1DEVA 3ELVA 2XT9B 2KFUA 1LGQA 5A8IA 3GMJA 1K3JA 5JEMA 5BVIA 2FEZA 1K3QA 1DD1A 5JEKA 3OUNA 4V24A 1U7FA 4QCJA 1MK2A 3UN0A 3VPYA 1J4PA 2JGRA 3UNNA 1KHXA 1J2FA 4WERA 2KB4A 4G2SA 1R21A 1WV3A 3I6WA 1U7VA 1K2MA 1G3GA 1MZKA 1J4LA 3A77A 1K2NA 2G1LA 4L02A 3HUEA 1K3NA 1DMZA 1QU5A 2BONA 2JQJA 3VA4A 1QWTA 3DSHA 4WRRA 3ELSA 1ZOQA 4A0EA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3POA A;  1J4K A;  3I6U A;  2BRF A;  1FHQ A;  3I0M A;  2JQL A;  3HUF A;  4H87 A;  2KKL A;  2JKD A;  4JON A;  2AFF A;  2JQI A;  4EJQ A;  2W3O A;  1UJX A;  3VA1 A;  2JPE A;  2FF4 A;  3UV0 A;  1LGP A;  1GXC A;  2CSW A;  3UOT A;  4D9V A;  3HX1 A;  1UHT A;  2KB3 A;  3UMZ A;  2PIE A;  3UNM A;  3I0N A;  1J4O A;  3MDB A;  1YJ5 C;  3GQS A;  2A0T A;  1G6G A;  1WLN A;  1FHR A;  3PO8 A;  3FM8 A;  2EH0 A;  3KT9 A;  5DJO A;  4EGX A;  1J4Q A;  5E50 A;  1YJM A;  2LC1 A;  3ELV A;  2XT9 B;  2KFU A;  1LGQ A;  5A8I A;  1K3J A;  2FEZ A;  1K3Q A;  3OUN A;  4QCJ A;  3UN0 A;  3VPY A;  1J4P A;  3UNN A;  2KB4 A;  4G2S A;  1R21 A;  1WV3 A;  3I6W A;  1K2M A;  1G3G A;  1MZK A;  1J4L A;  1K2N A;  2G1L A;  3HUE A;  1K3N A;  1DMZ A;  1QU5 A;  2JQJ A;  3VA4 A;  3ELS A;  4A0E A; 
#chains in the Genus database with same CATH topology
 3POA A;  1J4K A;  3V8R A;  3I6U A;  2I1W A;  2AN1 A;  2BRF A;  1FHQ A;  3V7Y A;  4A4Y A;  1Y3H A;  3I0M A;  2XXS A;  2JQL A;  1U0R A;  3VZD A;  1Z0S A;  3HUF A;  3V8P A;  1G88 A;  4H87 A;  3V8M A;  2KKL A;  3DIT A;  3T5P A;  2JKD A;  4JON A;  2AFF A;  2JQI A;  4EJQ A;  5JER A;  2W3O A;  5C4V A;  1UJX A;  3VA1 A;  2JPE A;  2FF4 A;  1Z0U A;  1LGP A;  3UV0 A;  5JEL A;  5JEJ A;  4JIW D;  1GXC A;  3ELS A;  2QVL A;  5EJG A;  2I2A A;  4JIV D;  2CSW A;  3UOT A;  4D9V A;  3VZC A;  3HX1 A;  1UHT A;  1U7F B;  5JEO A;  2QV7 A;  2KB3 A;  3UMZ A;  2PIE A;  3V7W A;  3AFO A;  3UNM A;  2I2B A;  3I0N A;  1J4O A;  3MDB A;  1YGS A;  1YJ5 C;  3GQS A;  2A0T A;  3V8Q A;  1G6G A;  1WLN A;  3VZB A;  3V7U A;  1MJS A;  1FHR A;  4KU0 D;  3PO8 A;  3FM8 A;  1U0T A;  2EH0 A;  3KT9 A;  2I29 A;  5EJH A;  3S40 A;  5DJO A;  4EGX A;  1U7V B;  1J4Q A;  1KHU A;  5DHP A;  4R9P A;  5EJI A;  2I2C A;  5E50 A;  1YJM A;  1MR1 A;  2LC1 A;  1DEV A;  1Z0Z A;  3ELV A;  2XT9 B;  1SUW A;  2KFU A;  3V8N A;  1LGQ A;  4HAO A;  5A8I A;  5DHU A;  1YT5 A;  3GMJ A;  1K3J A;  1Y3I A;  5JEM A;  5BVI A;  2FEZ A;  1K3Q A;  1DD1 A;  5DHR A;  5JEK A;  5DHQ A;  2I2D A;  3OUN A;  4V24 A;  1U7F A;  4QCJ A;  1MK2 A;  3UN0 A;  3VPY A;  1J4P A;  2JGR A;  3UNN A;  1KHX A;  2I2F A;  1J2F A;  5DHS A;  4WER A;  2KB4 A;  3PFN A;  4G2S A;  5DHT A;  1R21 A;  4DY6 A;  1WV3 A;  3I6W A;  2Q5F A;  1U7V A;  1K2M A;  1G3G A;  5EJF A;  1MZK A;  1J4L A;  3A77 A;  1K2N A;  2G1L A;  3V80 A;  4L02 A;  3HUE A;  1K3N A;  1DMZ A;  1QU5 A;  2BON A;  2JQJ A;  3VA4 A;  1QWT A;  3DSH A;  4WRR A;  2P1R A;  1ZOQ A;  4A0E A; 
#chains in the Genus database with same CATH homology
 3POA A;  1J4K A;  3I6U A;  2BRF A;  1FHQ A;  4A4Y A;  3I0M A;  2XXS A;  2JQL A;  3VZD A;  3HUF A;  1G88 A;  4H87 A;  2KKL A;  3DIT A;  3T5P A;  2JKD A;  4JON A;  2AFF A;  2JQI A;  4EJQ A;  5JER A;  2W3O A;  5C4V A;  1UJX A;  3VA1 A;  2JPE A;  2FF4 A;  3UV0 A;  1LGP A;  5JEL A;  5JEJ A;  4JIW D;  1GXC A;  2QVL A;  4JIV D;  2CSW A;  3UOT A;  4D9V A;  3VZC A;  3HX1 A;  1UHT A;  1U7F B;  5JEO A;  2QV7 A;  2KB3 A;  3UMZ A;  2PIE A;  3UNM A;  3I0N A;  1J4O A;  3MDB A;  1YGS A;  1YJ5 C;  2P1R A;  3GQS A;  2A0T A;  1G6G A;  1WLN A;  3VZB A;  1MJS A;  1FHR A;  4KU0 D;  3PO8 A;  3FM8 A;  2EH0 A;  3KT9 A;  3S40 A;  5DJO A;  4EGX A;  1U7V B;  1J4Q A;  1KHU A;  4R9P A;  5E50 A;  1YJM A;  1MR1 A;  2LC1 A;  1DEV A;  3ELV A;  2XT9 B;  2KFU A;  1LGQ A;  5A8I A;  3GMJ A;  1K3J A;  5JEM A;  5BVI A;  2FEZ A;  1K3Q A;  1DD1 A;  5JEK A;  3OUN A;  4V24 A;  1U7F A;  4QCJ A;  1MK2 A;  3UN0 A;  3VPY A;  1J4P A;  2JGR A;  3UNN A;  1KHX A;  1J2F A;  4WER A;  2KB4 A;  4G2S A;  1R21 A;  1WV3 A;  3I6W A;  1U7V A;  1K2M A;  1G3G A;  1MZK A;  1J4L A;  3A77 A;  1K2N A;  2G1L A;  4L02 A;  3HUE A;  1K3N A;  1DMZ A;  1QU5 A;  2BON A;  2JQJ A;  3VA4 A;  1QWT A;  3DSH A;  4WRR A;  3ELS A;  1ZOQ A;  4A0E A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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