1K2MA

Solution structure of the fha2 domain of rad53 complexed with a phosphotyrosyl peptide derived from rad9
Total Genus 24
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
24
sequence length
158
structure length
158
Chain Sequence
GNGRFLTLKPLPDSIIQESLEIQQGVNPFFIGRSEDCNCKIEDNRLSRVHCFIFKKRHAVGKSMYESPAQGLDDIWYCHTGTNVSYLNNNRMIQGTKFLLQDGDEIKIIWDKNNKFVIGFKVEINDTTGLFNEGLGMLQEQRVVLKQTAEEKDLVKKL
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Solution structure of the yeast Rad53 FHA2 complexed with a phosphothreonine peptide pTXXL: comparison with the structures of FHA2-pYXL and FHA1-pTXXD complexes.
pubmed doi rcsb
molecule tags Transferase
source organism Saccharomyces cerevisiae
molecule keywords Protein Kinase SPK1
total genus 24
structure length 158
sequence length 158
ec nomenclature ec 2.7.12.1: Dual-specificity kinase.
pdb deposition date 2001-09-28

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00498 FHA FHA domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.60.200.20 Mainly Beta Sandwich Tumour Suppressor Smad4 Tumour Suppressor Smad4 1k2mA00
2G1LA 3HUEA 1K3JA 1LGPA 3HX1A 4QCJA 2JPEA 3UMZA 2FEZA 2KFUA 4EGXA 1J4KA 1K3NA 2EH0A 1GXCA 1G6GA 3ELSA 2LC1A 2XT9B 3VPYA 2BRFA 3GQSA 5E50A 1K2NA 1WLNA 1FHRA 3POAA 2KKLA 2JQIA 1J4LA 2KB3A 1J4QA 2JQJA 2PIEA 1LGQA 2W3OA 3ELVA 4D9VA 1K2MA 4EJQA 3VA4A 3I0MA 1FHQA 3PO8A 3UN0A 3KT9A 3UNNA 1UHTA 3MDBA 2A0TA 3I0NA 1WV3A 3VA1A 3HUFA 5DJOA 2JKDA 3UV0A 3I6WA 1QU5A 1R21A 2FF4A 4G2SA 2KB4A 1G3GA 1YJMA 4H87A 1UJXA 1YJ5C 5A8IA 2AFFA 3I6UA 3FM8A 4JONA 4A0EA 2CSWA 1DMZA 3UOTA 1K3QA 3UNMA 1J4OA 2JQLA 3OUNA 1MZKA 1J4PA
chains in the Genus database with same CATH superfamily
2G1LA 3V8QA 1MR1A 3HUEA 1K3JA 1LGPA 3A77A 2I2AA 3HX1A 4JIVD 1Z0SA 1DD1A 4QCJA 5DHQA 2JPEA 3UMZA 5JEOA 1U7FA 5DHSA 2FEZA 2KFUA 3V8NA 4EGXA 1J4KA 1K3NA 3VZBA 2EH0A 5EJIA 4R9PA 1GXCA 1G6GA 2QVLA 2I2DA 4L02A 1SUWA 1ZOQA 3ELSA 2LC1A 2XT9B 3VPYA 2XXSA 2BRFA 3GQSA 5E50A 5EJGA 1K2NA 1WLNA 1FHRA 3POAA 1U7VA 4KU0D 3GMJA 2KKLA 2P1RA 3DSHA 2JQIA 1J4LA 5DHUA 5C4VA 1QWTA 2KB3A 5JELA 2I29A 1J4QA 3V7UA 4A4YA 1U7FB 2JQJA 2PIEA 1LGQA 2W3OA 3V8MA 3VZDA 3ELVA 4D9VA 1K2MA 5DHPA 3S40A 4EJQA 3VA4A 1YT5A 3I0MA 1FHQA 1U0TA 3V8RA 2I1WA 1Y3IA 1DEVA 3V7YA 1YGSA 2BONA 1G88A 4V24A 1U7VB 3PO8A 3UN0A 1Y3HA 3KT9A 3UNNA 1UHTA 3MDBA 5JERA 2A0TA 3I0NA 1WV3A 3VA1A 4DY6A 3HUFA 4WRRA 3V80A 5JEJA 5DHTA 5DHRA 5DJOA 2QV7A 1KHXA 2JKDA 1MJSA 2I2CA 3UV0A 3I6WA 1QU5A 5JEMA 1R21A 3PFNA 2FF4A 4G2SA 4HAOA 2KB4A 1G3GA 2AN1A 1YJMA 4H87A 3T5PA 3AFOA 1UJXA 3DITA 2I2FA 1YJ5C 1KHUA 2Q5FA 5A8IA 5BVIA 1MK2A 2AFFA 3I6UA 1J2FA 3FM8A 4JONA 4A0EA 3VZCA 2CSWA 4JIWD 1DMZA 5EJHA 4WERA 3UOTA 1K3QA 3UNMA 1J4OA 2JQLA 5EJFA 3OUNA 5JEKA 1Z0UA 2I2BA 1Z0ZA 1U0RA 2JGRA 3V7WA 1MZKA 1J4PA 3V8PA
chains in the Genus database with same CATH topology
2G1LA 1MR1A 3HUEA 1K3JA 1LGPA 3A77A 3HX1A 4JIVD 1DD1A 4QCJA 2JPEA 3UMZA 5JEOA 1U7FA 2FEZA 2KFUA 4EGXA 1J4KA 1K3NA 3VZBA 2EH0A 4R9PA 1GXCA 1G6GA 2QVLA 4L02A 1ZOQA 3ELSA 2LC1A 2XT9B 3VPYA 2XXSA 2BRFA 3GQSA 5E50A 1K2NA 1WLNA 1FHRA 3POAA 1U7VA 4KU0D 3GMJA 2KKLA 2P1RA 3DSHA 2JQIA 1J4LA 5C4VA 1QWTA 2KB3A 5JELA 1J4QA 4A4YA 1U7FB 2JQJA 2PIEA 1LGQA 2W3OA 3VZDA 3ELVA 4D9VA 1K2MA 3S40A 4EJQA 3VA4A 3I0MA 1FHQA 1DEVA 1YGSA 2BONA 1G88A 4V24A 1U7VB 3PO8A 3UN0A 3KT9A 3UNNA 1UHTA 3MDBA 5JERA 2A0TA 3I0NA 1WV3A 3VA1A 3HUFA 4WRRA 5JEJA 5DJOA 2QV7A 1KHXA 2JKDA 1MJSA 3UV0A 3I6WA 1QU5A 5JEMA 1R21A 2FF4A 4G2SA 2KB4A 1G3GA 1YJMA 4H87A 3T5PA 1UJXA 3DITA 1YJ5C 1KHUA 5A8IA 5BVIA 1MK2A 2AFFA 3I6UA 1J2FA 3FM8A 4JONA 4A0EA 3VZCA 2CSWA 4JIWD 1DMZA 4WERA 3UOTA 1K3QA 3UNMA 1J4OA 2JQLA 3OUNA 5JEKA 2JGRA 1MZKA 1J4PA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2G1L A;  3HUE A;  1K3J A;  1LGP A;  3HX1 A;  4QCJ A;  2JPE A;  3UMZ A;  2FEZ A;  2KFU A;  4EGX A;  1J4K A;  1K3N A;  2EH0 A;  1GXC A;  1G6G A;  3ELS A;  2LC1 A;  2XT9 B;  3VPY A;  2BRF A;  3GQS A;  5E50 A;  1K2N A;  1WLN A;  1FHR A;  3POA A;  2KKL A;  2JQI A;  1J4L A;  2KB3 A;  1J4Q A;  2JQJ A;  2PIE A;  1LGQ A;  2W3O A;  3ELV A;  4D9V A;  1K2M A;  4EJQ A;  3VA4 A;  3I0M A;  1FHQ A;  3PO8 A;  3UN0 A;  3KT9 A;  3UNN A;  1UHT A;  3MDB A;  2A0T A;  3I0N A;  1WV3 A;  3VA1 A;  3HUF A;  5DJO A;  2JKD A;  3UV0 A;  3I6W A;  1QU5 A;  1R21 A;  2FF4 A;  4G2S A;  2KB4 A;  1G3G A;  1YJM A;  4H87 A;  1UJX A;  1YJ5 C;  5A8I A;  2AFF A;  3I6U A;  3FM8 A;  4JON A;  4A0E A;  2CSW A;  1DMZ A;  3UOT A;  1K3Q A;  3UNM A;  1J4O A;  2JQL A;  3OUN A;  1MZK A;  1J4P A; 
#chains in the Genus database with same CATH topology
 2G1L A;  3V8Q A;  1MR1 A;  3HUE A;  1K3J A;  1LGP A;  3A77 A;  2I2A A;  3HX1 A;  4JIV D;  1Z0S A;  1DD1 A;  4QCJ A;  5DHQ A;  2JPE A;  3UMZ A;  5JEO A;  1U7F A;  5DHS A;  2FEZ A;  2KFU A;  3V8N A;  4EGX A;  1J4K A;  1K3N A;  3VZB A;  2EH0 A;  5EJI A;  4R9P A;  1GXC A;  1G6G A;  2QVL A;  2I2D A;  4L02 A;  1SUW A;  1ZOQ A;  3ELS A;  2LC1 A;  2XT9 B;  3VPY A;  2XXS A;  2BRF A;  3GQS A;  5E50 A;  5EJG A;  1K2N A;  1WLN A;  1FHR A;  3POA A;  1U7V A;  4KU0 D;  3GMJ A;  2KKL A;  2P1R A;  3DSH A;  2JQI A;  1J4L A;  5DHU A;  5C4V A;  1QWT A;  2KB3 A;  5JEL A;  2I29 A;  1J4Q A;  3V7U A;  4A4Y A;  1U7F B;  2JQJ A;  2PIE A;  1LGQ A;  2W3O A;  3V8M A;  3VZD A;  3ELV A;  4D9V A;  1K2M A;  5DHP A;  3S40 A;  4EJQ A;  3VA4 A;  1YT5 A;  3I0M A;  1FHQ A;  1U0T A;  3V8R A;  2I1W A;  1Y3I A;  1DEV A;  3V7Y A;  1YGS A;  2BON A;  1G88 A;  4V24 A;  1U7V B;  3PO8 A;  3UN0 A;  1Y3H A;  3KT9 A;  3UNN A;  1UHT A;  3MDB A;  5JER A;  2A0T A;  3I0N A;  1WV3 A;  3VA1 A;  4DY6 A;  3HUF A;  4WRR A;  3V80 A;  5JEJ A;  5DHT A;  5DHR A;  5DJO A;  2QV7 A;  1KHX A;  2JKD A;  1MJS A;  2I2C A;  3UV0 A;  3I6W A;  1QU5 A;  5JEM A;  1R21 A;  3PFN A;  2FF4 A;  4G2S A;  4HAO A;  2KB4 A;  1G3G A;  2AN1 A;  1YJM A;  4H87 A;  3T5P A;  3AFO A;  1UJX A;  3DIT A;  2I2F A;  1YJ5 C;  1KHU A;  2Q5F A;  5A8I A;  5BVI A;  1MK2 A;  2AFF A;  3I6U A;  1J2F A;  3FM8 A;  4JON A;  4A0E A;  3VZC A;  2CSW A;  4JIW D;  1DMZ A;  5EJH A;  4WER A;  3UOT A;  1K3Q A;  3UNM A;  1J4O A;  2JQL A;  5EJF A;  3OUN A;  5JEK A;  1Z0U A;  2I2B A;  1Z0Z A;  1U0R A;  2JGR A;  3V7W A;  1MZK A;  1J4P A;  3V8P A; 
#chains in the Genus database with same CATH homology
 2G1L A;  1MR1 A;  3HUE A;  1K3J A;  1LGP A;  3A77 A;  3HX1 A;  4JIV D;  1DD1 A;  4QCJ A;  2JPE A;  3UMZ A;  5JEO A;  1U7F A;  2FEZ A;  2KFU A;  4EGX A;  1J4K A;  1K3N A;  3VZB A;  2EH0 A;  4R9P A;  1GXC A;  1G6G A;  2QVL A;  4L02 A;  1ZOQ A;  3ELS A;  2LC1 A;  2XT9 B;  3VPY A;  2XXS A;  2BRF A;  3GQS A;  5E50 A;  1K2N A;  1WLN A;  1FHR A;  3POA A;  1U7V A;  4KU0 D;  3GMJ A;  2KKL A;  2P1R A;  3DSH A;  2JQI A;  1J4L A;  5C4V A;  1QWT A;  2KB3 A;  5JEL A;  1J4Q A;  4A4Y A;  1U7F B;  2JQJ A;  2PIE A;  1LGQ A;  2W3O A;  3VZD A;  3ELV A;  4D9V A;  1K2M A;  3S40 A;  4EJQ A;  3VA4 A;  3I0M A;  1FHQ A;  1DEV A;  1YGS A;  2BON A;  1G88 A;  4V24 A;  1U7V B;  3PO8 A;  3UN0 A;  3KT9 A;  3UNN A;  1UHT A;  3MDB A;  5JER A;  2A0T A;  3I0N A;  1WV3 A;  3VA1 A;  3HUF A;  4WRR A;  5JEJ A;  5DJO A;  2QV7 A;  1KHX A;  2JKD A;  1MJS A;  3UV0 A;  3I6W A;  1QU5 A;  5JEM A;  1R21 A;  2FF4 A;  4G2S A;  2KB4 A;  1G3G A;  1YJM A;  4H87 A;  3T5P A;  1UJX A;  3DIT A;  1YJ5 C;  1KHU A;  5A8I A;  5BVI A;  1MK2 A;  2AFF A;  3I6U A;  1J2F A;  3FM8 A;  4JON A;  4A0E A;  3VZC A;  2CSW A;  4JIW D;  1DMZ A;  4WER A;  3UOT A;  1K3Q A;  3UNM A;  1J4O A;  2JQL A;  3OUN A;  5JEK A;  2JGR A;  1MZK A;  1J4P A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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