1K2MA

Solution structure of the fha2 domain of rad53 complexed with a phosphotyrosyl peptide derived from rad9
Total Genus 24
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
24
sequence length
158
structure length
158
Chain Sequence
GNGRFLTLKPLPDSIIQESLEIQQGVNPFFIGRSEDCNCKIEDNRLSRVHCFIFKKRHAVGKSMYESPAQGLDDIWYCHTGTNVSYLNNNRMIQGTKFLLQDGDEIKIIWDKNNKFVIGFKVEINDTTGLFNEGLGMLQEQRVVLKQTAEEKDLVKKL
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Solution structure of the yeast Rad53 FHA2 complexed with a phosphothreonine peptide pTXXL: comparison with the structures of FHA2-pYXL and FHA1-pTXXD complexes.
pubmed doi rcsb
molecule tags Transferase
source organism Saccharomyces cerevisiae
molecule keywords Protein Kinase SPK1
total genus 24
structure length 158
sequence length 158
ec nomenclature ec 2.7.12.1: Dual-specificity kinase.
pdb deposition date 2001-09-28

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00498 FHA FHA domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.60.200.20 Mainly Beta Sandwich Tumour Suppressor Smad4 Tumour Suppressor Smad4 1k2mA00
3KT9A 1WLNA 3ELVA 1G3GA 3UNNA 1J4QA 3I6UA 5E50A 1FHQA 1QU5A 1R21A 2KKLA 1LGPA 2EH0A 1J4PA 3I6WA 3HUEA 3HUFA 3MDBA 2A0TA 3GQSA 1K3QA 1UHTA 1FHRA 2JQLA 1WV3A 2FEZA 4G2SA 3HX1A 1K3NA 5A8IA 2LC1A 2JQJA 1YJMA 1MZKA 3ELSA 4EGXA 3I0MA 3VA1A 4QCJA 3UNMA 1LGQA 2PIEA 2CSWA 1J4LA 2BRFA 2G1LA 3UV0A 1GXCA 1K3JA 2W3OA 2KB3A 1K2MA 2AFFA 1J4KA 5DJOA 2KB4A 3UMZA 3OUNA 4EJQA 4H87A 3VPYA 3UN0A 3I0NA 2KFUA 1K2NA 1YJ5C 2JKDA 1J4OA 1G6GA 3POAA 2XT9B 3VA4A 4JONA 3UOTA 1UJXA 2JQIA 1DMZA 3FM8A 3PO8A 2JPEA 2FF4A 4D9VA 4A0EA
chains in the Genus database with same CATH superfamily
1U0TA 3KT9A 1U7VA 1WLNA 3V80A 4JIWD 3ELVA 1G3GA 3UNNA 2Q5FA 4A4YA 3V7WA 1U0RA 1J4QA 2QV7A 3I6UA 5E50A 1FHQA 3T5PA 1QU5A 1R21A 2I2CA 2KKLA 4JIVD 1LGPA 2EH0A 5DHPA 1J4PA 1YT5A 3I6WA 3HUEA 3HUFA 3MDBA 5DHUA 2A0TA 1DEVA 3V8MA 3GQSA 1K3QA 1UHTA 3A77A 2JQLA 2BONA 1FHRA 5EJIA 1WV3A 3DITA 2FEZA 3V8NA 1U7FA 4G2SA 1QWTA 5DHTA 4HAOA 5JEJA 3HX1A 2JGRA 1K3NA 1Z0SA 4KU0D 5A8IA 2LC1A 3V7YA 3V8RA 2JQJA 1YJMA 5C4VA 2I29A 1MZKA 3ELSA 5EJHA 4EGXA 1ZOQA 3I0MA 3VA1A 4QCJA 5EJFA 3UNMA 1LGQA 2PIEA 2CSWA 3DSHA 1J4LA 1SUWA 1YGSA 1Y3HA 1Z0UA 2BRFA 4DY6A 2G1LA 3UV0A 1GXCA 2XXSA 1K3JA 1U7VB 1U7FB 2W3OA 3VZDA 4V24A 3AFOA 2I2AA 2KB3A 1MK2A 2I1WA 1K2MA 5BVIA 5DHSA 4R9PA 2AFFA 1J4KA 5DJOA 2I2BA 2QVLA 1MJSA 3S40A 5EJGA 3PFNA 2KB4A 3UMZA 3OUNA 4EJQA 4H87A 1MR1A 4WERA 3V8QA 3VPYA 3VZCA 2I2FA 3UN0A 5JEKA 1DD1A 2AN1A 3I0NA 2KFUA 1Y3IA 1K2NA 5DHQA 4L02A 1YJ5C 1G88A 3GMJA 2JKDA 1G6GA 1J4OA 3POAA 2XT9B 3VA4A 5JEMA 5JEOA 3V7UA 4WRRA 4JONA 5DHRA 3UOTA 2JQIA 1UJXA 1DMZA 3FM8A 3V8PA 5JELA 5JERA 2P1RA 2I2DA 3PO8A 1J2FA 2JPEA 2FF4A 1KHUA 1Z0ZA 4D9VA 3VZBA 4A0EA 1KHXA
chains in the Genus database with same CATH topology
3KT9A 1U7VA 1WLNA 4JIWD 3ELVA 1G3GA 3UNNA 4A4YA 1J4QA 2QV7A 3I6UA 5E50A 1FHQA 3T5PA 1QU5A 1R21A 2KKLA 4JIVD 1LGPA 2EH0A 1J4PA 3I6WA 3HUEA 3HUFA 3MDBA 2A0TA 1DEVA 3GQSA 1K3QA 1UHTA 3A77A 2JQLA 2BONA 1FHRA 1WV3A 3DITA 2FEZA 1U7FA 4G2SA 1QWTA 5JEJA 3HX1A 2JGRA 1K3NA 4KU0D 5A8IA 2LC1A 2JQJA 1YJMA 5C4VA 1MZKA 3ELSA 4EGXA 1ZOQA 3I0MA 3VA1A 4QCJA 3UNMA 1LGQA 2PIEA 3DSHA 2CSWA 1J4LA 1YGSA 2BRFA 2G1LA 3UV0A 1GXCA 2XXSA 1K3JA 1U7VB 1U7FB 2W3OA 3VZDA 4V24A 2KB3A 1MK2A 1K2MA 5BVIA 4R9PA 2AFFA 1J4KA 5DJOA 2QVLA 3S40A 1MJSA 2KB4A 3UMZA 3OUNA 4EJQA 4H87A 1MR1A 4WERA 3VPYA 3VZCA 3UN0A 5JEKA 1DD1A 3I0NA 2KFUA 1K2NA 4L02A 1YJ5C 1G88A 3GMJA 2JKDA 1G6GA 1J4OA 3POAA 2XT9B 3VA4A 5JEMA 5JEOA 4WRRA 4JONA 3UOTA 1UJXA 2JQIA 1DMZA 3FM8A 5JERA 5JELA 2P1RA 3PO8A 1J2FA 2JPEA 2FF4A 1KHUA 4D9VA 3VZBA 4A0EA 1KHXA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3KT9 A;  1WLN A;  3ELV A;  1G3G A;  3UNN A;  1J4Q A;  3I6U A;  5E50 A;  1FHQ A;  1QU5 A;  1R21 A;  2KKL A;  1LGP A;  2EH0 A;  1J4P A;  3I6W A;  3HUE A;  3HUF A;  3MDB A;  2A0T A;  3GQS A;  1K3Q A;  1UHT A;  1FHR A;  2JQL A;  1WV3 A;  2FEZ A;  4G2S A;  3HX1 A;  1K3N A;  5A8I A;  2LC1 A;  2JQJ A;  1YJM A;  1MZK A;  3ELS A;  4EGX A;  3I0M A;  3VA1 A;  4QCJ A;  3UNM A;  1LGQ A;  2PIE A;  2CSW A;  1J4L A;  2BRF A;  2G1L A;  3UV0 A;  1GXC A;  1K3J A;  2W3O A;  2KB3 A;  1K2M A;  2AFF A;  1J4K A;  5DJO A;  2KB4 A;  3UMZ A;  3OUN A;  4EJQ A;  4H87 A;  3VPY A;  3UN0 A;  3I0N A;  2KFU A;  1K2N A;  1YJ5 C;  2JKD A;  1J4O A;  1G6G A;  3POA A;  2XT9 B;  3VA4 A;  4JON A;  3UOT A;  1UJX A;  2JQI A;  1DMZ A;  3FM8 A;  3PO8 A;  2JPE A;  2FF4 A;  4D9V A;  4A0E A; 
#chains in the Genus database with same CATH topology
 1U0T A;  3KT9 A;  1U7V A;  1WLN A;  3V80 A;  4JIW D;  3ELV A;  1G3G A;  3UNN A;  2Q5F A;  4A4Y A;  3V7W A;  1U0R A;  1J4Q A;  2QV7 A;  3I6U A;  5E50 A;  1FHQ A;  3T5P A;  1QU5 A;  1R21 A;  2I2C A;  2KKL A;  4JIV D;  1LGP A;  2EH0 A;  5DHP A;  1J4P A;  1YT5 A;  3I6W A;  3HUE A;  3HUF A;  3MDB A;  5DHU A;  2A0T A;  1DEV A;  3V8M A;  3GQS A;  1K3Q A;  1UHT A;  3A77 A;  2JQL A;  2BON A;  1FHR A;  5EJI A;  1WV3 A;  3DIT A;  2FEZ A;  3V8N A;  1U7F A;  4G2S A;  1QWT A;  5DHT A;  4HAO A;  5JEJ A;  3HX1 A;  2JGR A;  1K3N A;  1Z0S A;  4KU0 D;  5A8I A;  2LC1 A;  3V7Y A;  3V8R A;  2JQJ A;  1YJM A;  5C4V A;  2I29 A;  1MZK A;  3ELS A;  5EJH A;  4EGX A;  1ZOQ A;  3I0M A;  3VA1 A;  4QCJ A;  5EJF A;  3UNM A;  1LGQ A;  2PIE A;  2CSW A;  3DSH A;  1J4L A;  1SUW A;  1YGS A;  1Y3H A;  1Z0U A;  2BRF A;  4DY6 A;  2G1L A;  3UV0 A;  1GXC A;  2XXS A;  1K3J A;  1U7V B;  1U7F B;  2W3O A;  3VZD A;  4V24 A;  3AFO A;  2I2A A;  2KB3 A;  1MK2 A;  2I1W A;  1K2M A;  5BVI A;  5DHS A;  4R9P A;  2AFF A;  1J4K A;  5DJO A;  2I2B A;  2QVL A;  1MJS A;  3S40 A;  5EJG A;  3PFN A;  2KB4 A;  3UMZ A;  3OUN A;  4EJQ A;  4H87 A;  1MR1 A;  4WER A;  3V8Q A;  3VPY A;  3VZC A;  2I2F A;  3UN0 A;  5JEK A;  1DD1 A;  2AN1 A;  3I0N A;  2KFU A;  1Y3I A;  1K2N A;  5DHQ A;  4L02 A;  1YJ5 C;  1G88 A;  3GMJ A;  2JKD A;  1G6G A;  1J4O A;  3POA A;  2XT9 B;  3VA4 A;  5JEM A;  5JEO A;  3V7U A;  4WRR A;  4JON A;  5DHR A;  3UOT A;  2JQI A;  1UJX A;  1DMZ A;  3FM8 A;  3V8P A;  5JEL A;  5JER A;  2P1R A;  2I2D A;  3PO8 A;  1J2F A;  2JPE A;  2FF4 A;  1KHU A;  1Z0Z A;  4D9V A;  3VZB A;  4A0E A;  1KHX A; 
#chains in the Genus database with same CATH homology
 3KT9 A;  1U7V A;  1WLN A;  4JIW D;  3ELV A;  1G3G A;  3UNN A;  4A4Y A;  1J4Q A;  2QV7 A;  3I6U A;  5E50 A;  1FHQ A;  3T5P A;  1QU5 A;  1R21 A;  2KKL A;  4JIV D;  1LGP A;  2EH0 A;  1J4P A;  3I6W A;  3HUE A;  3HUF A;  3MDB A;  2A0T A;  1DEV A;  3GQS A;  1K3Q A;  1UHT A;  3A77 A;  2JQL A;  2BON A;  1FHR A;  1WV3 A;  3DIT A;  2FEZ A;  1U7F A;  4G2S A;  1QWT A;  5JEJ A;  3HX1 A;  2JGR A;  1K3N A;  4KU0 D;  5A8I A;  2LC1 A;  2JQJ A;  1YJM A;  5C4V A;  1MZK A;  3ELS A;  4EGX A;  1ZOQ A;  3I0M A;  3VA1 A;  4QCJ A;  3UNM A;  1LGQ A;  2PIE A;  3DSH A;  2CSW A;  1J4L A;  1YGS A;  2BRF A;  2G1L A;  3UV0 A;  1GXC A;  2XXS A;  1K3J A;  1U7V B;  1U7F B;  2W3O A;  3VZD A;  4V24 A;  2KB3 A;  1MK2 A;  1K2M A;  5BVI A;  4R9P A;  2AFF A;  1J4K A;  5DJO A;  2QVL A;  3S40 A;  1MJS A;  2KB4 A;  3UMZ A;  3OUN A;  4EJQ A;  4H87 A;  1MR1 A;  4WER A;  3VPY A;  3VZC A;  3UN0 A;  5JEK A;  1DD1 A;  3I0N A;  2KFU A;  1K2N A;  4L02 A;  1YJ5 C;  1G88 A;  3GMJ A;  2JKD A;  1G6G A;  1J4O A;  3POA A;  2XT9 B;  3VA4 A;  5JEM A;  5JEO A;  4WRR A;  4JON A;  3UOT A;  1UJX A;  2JQI A;  1DMZ A;  3FM8 A;  5JER A;  5JEL A;  2P1R A;  3PO8 A;  1J2F A;  2JPE A;  2FF4 A;  1KHU A;  4D9V A;  3VZB A;  4A0E A;  1KHX A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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