1K2NA

Solution structure of the fha2 domain of rad53 complexed with a phosphothreonyl peptide derived from rad9
Total Genus 22
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
22
sequence length
158
structure length
158
Chain Sequence
GNGRFLTLKPLPDSIIQESLEIQQGVNPFFIGRSEDCNCKIEDNRLSRVHCFIFKKRHAVGKSMYESPAQGLDDIWYCHTGTNVSYLNNNRMIQGTKFLLQDGDEIKIIWDKNNKFVIGFKVEINDTTGLFNEGLGMLQEQRVVLKQTAEEKDLVKKL
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Solution structure of the yeast Rad53 FHA2 complexed with a phosphothreonine peptide pTXXL: comparison with the structures of FHA2-pYXL and FHA1-pTXXD complexes.
pubmed doi rcsb
molecule tags Transferase
source organism Saccharomyces cerevisiae
molecule keywords Protein Kinase SPK1
total genus 22
structure length 158
sequence length 158
ec nomenclature ec 2.7.12.1: Dual-specificity kinase.
pdb deposition date 2001-09-28

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00498 FHA FHA domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.60.200.20 Mainly Beta Sandwich Tumour Suppressor Smad4 Tumour Suppressor Smad4 1k2nA00
4QCJA 3HUEA 3HUFA 2KFUA 3VA1A 3GQSA 2KB3A 1LGPA 2BRFA 1FHQA 1UHTA 1FHRA 2AFFA 1WLNA 3I6UA 2PIEA 3UN0A 2FF4A 1K3JA 1WV3A 3UMZA 3VPYA 3VA4A 3UV0A 1K3QA 2JQIA 4EJQA 1K2NA 3ELVA 1K3NA 2A0TA 1R21A 1LGQA 3I6WA 4JONA 2JQJA 1J4KA 2LC1A 4EGXA 2W3OA 4H87A 1QU5A 3HX1A 1GXCA 1DMZA 2JPEA 1MZKA 3I0MA 1UJXA 2KB4A 2JKDA 5DJOA 1J4PA 2EH0A 2JQLA 1K2MA 3I0NA 3POAA 3PO8A 3OUNA 5E50A 3UOTA 3UNMA 3KT9A 5A8IA 1YJMA 1J4QA 2CSWA 2G1LA 1J4LA 3ELSA 4D9VA 2KKLA 1G6GA 1G3GA 2FEZA 2XT9B 1J4OA 3UNNA 1YJ5C 3FM8A 3MDBA 4G2SA 4A0EA
chains in the Genus database with same CATH superfamily
4QCJA 3HUEA 3HUFA 2KFUA 4L02A 1MJSA 3V8QA 3VA1A 3GQSA 2KB3A 1LGPA 2BRFA 1FHQA 5DHPA 1UHTA 3A77A 1FHRA 2AFFA 1WLNA 3I6UA 2PIEA 3UN0A 1YGSA 4A4YA 1Z0UA 2P1RA 2FF4A 1K3JA 1WV3A 3UMZA 3VPYA 3VA4A 3DSHA 3VZBA 3UV0A 5EJGA 5C4VA 1K3QA 2JQIA 4EJQA 1MR1A 3V8NA 3V8MA 5DHSA 1K2NA 2I2FA 1Y3IA 4R9PA 3ELVA 4KU0D 3V7WA 1K3NA 2A0TA 1R21A 5BVIA 2QV7A 1LGQA 3AFOA 3I6WA 4JONA 2JQJA 1J4KA 4HAOA 2LC1A 4EGXA 5JERA 2W3OA 2BONA 3V8RA 4H87A 2JGRA 5DHQA 1QU5A 3HX1A 1GXCA 3V80A 2JPEA 4JIWD 1J2FA 1MZKA 1DMZA 2I29A 3GMJA 3I0MA 1U7VB 3V8PA 1UJXA 2KB4A 2JKDA 4WRRA 2I2CA 2I2BA 4DY6A 3VZDA 2Q5FA 3S40A 1DD1A 5DJOA 1KHUA 1J4PA 1U7VA 5EJFA 1U0TA 3V7UA 2I1WA 2EH0A 5DHTA 1YT5A 2JQLA 5JEJA 4JIVD 3T5PA 1K2MA 1U0RA 4WERA 3I0NA 3POAA 5EJIA 3PO8A 3OUNA 5JEMA 3VZCA 5E50A 3UOTA 2I2DA 1G88A 3PFNA 1KHXA 1U7FB 1Y3HA 3UNMA 3KT9A 5A8IA 2QVLA 1MK2A 1YJMA 5DHUA 2XXSA 1Z0ZA 1J4QA 1DEVA 1U7FA 2CSWA 2AN1A 2G1LA 1J4LA 3ELSA 1QWTA 4D9VA 2KKLA 1G6GA 1G3GA 1SUWA 1ZOQA 2FEZA 3DITA 5DHRA 4V24A 2XT9B 5JELA 1J4OA 3V7YA 5EJHA 1YJ5C 3FM8A 3UNNA 3MDBA 1Z0SA 5JEOA 2I2AA 4G2SA 4A0EA 5JEKA
chains in the Genus database with same CATH topology
4QCJA 3HUEA 3HUFA 2KFUA 4L02A 1MJSA 3VA1A 3GQSA 2KB3A 1LGPA 2BRFA 1FHQA 1UHTA 3A77A 1FHRA 2AFFA 1WLNA 3I6UA 2PIEA 3UN0A 1YGSA 4A4YA 2P1RA 2FF4A 1K3JA 1WV3A 3UMZA 3VPYA 3VA4A 3DSHA 3VZBA 3UV0A 5C4VA 1K3QA 2JQIA 4EJQA 1MR1A 1K2NA 4R9PA 3ELVA 4KU0D 1K3NA 2A0TA 1R21A 5BVIA 2QV7A 1LGQA 3I6WA 4JONA 2JQJA 1J4KA 2LC1A 4EGXA 5JERA 2W3OA 2BONA 4H87A 2JGRA 1QU5A 3HX1A 1GXCA 2JPEA 4JIWD 1J2FA 1MZKA 1DMZA 3GMJA 3I0MA 1U7VB 1UJXA 2KB4A 2JKDA 4WRRA 3VZDA 3S40A 1DD1A 5DJOA 1KHUA 1J4PA 1U7VA 2EH0A 2JQLA 5JEJA 4JIVD 3T5PA 1K2MA 4WERA 3I0NA 3POAA 3PO8A 3OUNA 5JEMA 3VZCA 5E50A 3UOTA 1G88A 1KHXA 1U7FB 3UNMA 3KT9A 5A8IA 2QVLA 1MK2A 1YJMA 2XXSA 1J4QA 1DEVA 1U7FA 2CSWA 2G1LA 1J4LA 3ELSA 1QWTA 4D9VA 2KKLA 1G6GA 1G3GA 1ZOQA 2FEZA 3DITA 5JELA 4V24A 2XT9B 1J4OA 3UNNA 1YJ5C 3FM8A 3MDBA 5JEOA 4G2SA 4A0EA 5JEKA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4QCJ A;  3HUE A;  3HUF A;  2KFU A;  3VA1 A;  3GQS A;  2KB3 A;  1LGP A;  2BRF A;  1FHQ A;  1UHT A;  1FHR A;  2AFF A;  1WLN A;  3I6U A;  2PIE A;  3UN0 A;  2FF4 A;  1K3J A;  1WV3 A;  3UMZ A;  3VPY A;  3VA4 A;  3UV0 A;  1K3Q A;  2JQI A;  4EJQ A;  1K2N A;  3ELV A;  1K3N A;  2A0T A;  1R21 A;  1LGQ A;  3I6W A;  4JON A;  2JQJ A;  1J4K A;  2LC1 A;  4EGX A;  2W3O A;  4H87 A;  1QU5 A;  3HX1 A;  1GXC A;  1DMZ A;  2JPE A;  1MZK A;  3I0M A;  1UJX A;  2KB4 A;  2JKD A;  5DJO A;  1J4P A;  2EH0 A;  2JQL A;  1K2M A;  3I0N A;  3POA A;  3PO8 A;  3OUN A;  5E50 A;  3UOT A;  3UNM A;  3KT9 A;  5A8I A;  1YJM A;  1J4Q A;  2CSW A;  2G1L A;  1J4L A;  3ELS A;  4D9V A;  2KKL A;  1G6G A;  1G3G A;  2FEZ A;  2XT9 B;  1J4O A;  3UNN A;  1YJ5 C;  3FM8 A;  3MDB A;  4G2S A;  4A0E A; 
#chains in the Genus database with same CATH topology
 4QCJ A;  3HUE A;  3HUF A;  2KFU A;  4L02 A;  1MJS A;  3V8Q A;  3VA1 A;  3GQS A;  2KB3 A;  1LGP A;  2BRF A;  1FHQ A;  5DHP A;  1UHT A;  3A77 A;  1FHR A;  2AFF A;  1WLN A;  3I6U A;  2PIE A;  3UN0 A;  1YGS A;  4A4Y A;  1Z0U A;  2P1R A;  2FF4 A;  1K3J A;  1WV3 A;  3UMZ A;  3VPY A;  3VA4 A;  3DSH A;  3VZB A;  3UV0 A;  5EJG A;  5C4V A;  1K3Q A;  2JQI A;  4EJQ A;  1MR1 A;  3V8N A;  3V8M A;  5DHS A;  1K2N A;  2I2F A;  1Y3I A;  4R9P A;  3ELV A;  4KU0 D;  3V7W A;  1K3N A;  2A0T A;  1R21 A;  5BVI A;  2QV7 A;  1LGQ A;  3AFO A;  3I6W A;  4JON A;  2JQJ A;  1J4K A;  4HAO A;  2LC1 A;  4EGX A;  5JER A;  2W3O A;  2BON A;  3V8R A;  4H87 A;  2JGR A;  5DHQ A;  1QU5 A;  3HX1 A;  1GXC A;  3V80 A;  2JPE A;  4JIW D;  1J2F A;  1MZK A;  1DMZ A;  2I29 A;  3GMJ A;  3I0M A;  1U7V B;  3V8P A;  1UJX A;  2KB4 A;  2JKD A;  4WRR A;  2I2C A;  2I2B A;  4DY6 A;  3VZD A;  2Q5F A;  3S40 A;  1DD1 A;  5DJO A;  1KHU A;  1J4P A;  1U7V A;  5EJF A;  1U0T A;  3V7U A;  2I1W A;  2EH0 A;  5DHT A;  1YT5 A;  2JQL A;  5JEJ A;  4JIV D;  3T5P A;  1K2M A;  1U0R A;  4WER A;  3I0N A;  3POA A;  5EJI A;  3PO8 A;  3OUN A;  5JEM A;  3VZC A;  5E50 A;  3UOT A;  2I2D A;  1G88 A;  3PFN A;  1KHX A;  1U7F B;  1Y3H A;  3UNM A;  3KT9 A;  5A8I A;  2QVL A;  1MK2 A;  1YJM A;  5DHU A;  2XXS A;  1Z0Z A;  1J4Q A;  1DEV A;  1U7F A;  2CSW A;  2AN1 A;  2G1L A;  1J4L A;  3ELS A;  1QWT A;  4D9V A;  2KKL A;  1G6G A;  1G3G A;  1SUW A;  1ZOQ A;  2FEZ A;  3DIT A;  5DHR A;  4V24 A;  2XT9 B;  5JEL A;  1J4O A;  3V7Y A;  5EJH A;  1YJ5 C;  3FM8 A;  3UNN A;  3MDB A;  1Z0S A;  5JEO A;  2I2A A;  4G2S A;  4A0E A;  5JEK A; 
#chains in the Genus database with same CATH homology
 4QCJ A;  3HUE A;  3HUF A;  2KFU A;  4L02 A;  1MJS A;  3VA1 A;  3GQS A;  2KB3 A;  1LGP A;  2BRF A;  1FHQ A;  1UHT A;  3A77 A;  1FHR A;  2AFF A;  1WLN A;  3I6U A;  2PIE A;  3UN0 A;  1YGS A;  4A4Y A;  2P1R A;  2FF4 A;  1K3J A;  1WV3 A;  3UMZ A;  3VPY A;  3VA4 A;  3DSH A;  3VZB A;  3UV0 A;  5C4V A;  1K3Q A;  2JQI A;  4EJQ A;  1MR1 A;  1K2N A;  4R9P A;  3ELV A;  4KU0 D;  1K3N A;  2A0T A;  1R21 A;  5BVI A;  2QV7 A;  1LGQ A;  3I6W A;  4JON A;  2JQJ A;  1J4K A;  2LC1 A;  4EGX A;  5JER A;  2W3O A;  2BON A;  4H87 A;  2JGR A;  1QU5 A;  3HX1 A;  1GXC A;  2JPE A;  4JIW D;  1J2F A;  1MZK A;  1DMZ A;  3GMJ A;  3I0M A;  1U7V B;  1UJX A;  2KB4 A;  2JKD A;  4WRR A;  3VZD A;  3S40 A;  1DD1 A;  5DJO A;  1KHU A;  1J4P A;  1U7V A;  2EH0 A;  2JQL A;  5JEJ A;  4JIV D;  3T5P A;  1K2M A;  4WER A;  3I0N A;  3POA A;  3PO8 A;  3OUN A;  5JEM A;  3VZC A;  5E50 A;  3UOT A;  1G88 A;  1KHX A;  1U7F B;  3UNM A;  3KT9 A;  5A8I A;  2QVL A;  1MK2 A;  1YJM A;  2XXS A;  1J4Q A;  1DEV A;  1U7F A;  2CSW A;  2G1L A;  1J4L A;  3ELS A;  1QWT A;  4D9V A;  2KKL A;  1G6G A;  1G3G A;  1ZOQ A;  2FEZ A;  3DIT A;  5JEL A;  4V24 A;  2XT9 B;  1J4O A;  3UNN A;  1YJ5 C;  3FM8 A;  3MDB A;  5JEO A;  4G2S A;  4A0E A;  5JEK A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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