1K2NA

Solution structure of the fha2 domain of rad53 complexed with a phosphothreonyl peptide derived from rad9
Total Genus 22
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
22
sequence length
158
structure length
158
Chain Sequence
GNGRFLTLKPLPDSIIQESLEIQQGVNPFFIGRSEDCNCKIEDNRLSRVHCFIFKKRHAVGKSMYESPAQGLDDIWYCHTGTNVSYLNNNRMIQGTKFLLQDGDEIKIIWDKNNKFVIGFKVEINDTTGLFNEGLGMLQEQRVVLKQTAEEKDLVKKL
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title Solution structure of the yeast Rad53 FHA2 complexed with a phosphothreonine peptide pTXXL: comparison with the structures of FHA2-pYXL and FHA1-pTXXD complexes.
pubmed doi rcsb
molecule tags Transferase
source organism Saccharomyces cerevisiae
molecule keywords Protein Kinase SPK1
total genus 22
structure length 158
sequence length 158
ec nomenclature ec 2.7.12.1: Dual-specificity kinase.
pdb deposition date 2001-09-28

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00498 FHA FHA domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.60.200.20 Mainly Beta Sandwich Tumour Suppressor Smad4 Tumour Suppressor Smad4 1k2nA00
1GXCA 3POAA 1DMZA 5E50A 2EH0A 1FHRA 3VPYA 1MZKA 4D9VA 1J4QA 2JQIA 2FF4A 2KKLA 1FHQA 3UMZA 3OUNA 2A0TA 1G6GA 3ELVA 2PIEA 1K3QA 3UV0A 4H87A 3GQSA 2CSWA 1LGQA 3KT9A 1LGPA 1UJXA 3MDBA 3I0MA 3I0NA 5DJOA 4A0EA 3UN0A 1UHTA 1G3GA 2JKDA 3UOTA 2W3OA 1K2NA 3HUFA 2KB3A 2AFFA 3VA4A 3HUEA 1J4PA 3UNMA 1K2MA 1YJ5C 2JQLA 1J4LA 2XT9B 4EGXA 2KFUA 1YJMA 5A8IA 4QCJA 2LC1A 1K3JA 4G2SA 1WV3A 1J4OA 2BRFA 2JPEA 2JQJA 1K3NA 2FEZA 3I6WA 3PO8A 1J4KA 2G1LA 4EJQA 1QU5A 3HX1A 3I6UA 3FM8A 1WLNA 3VA1A 2KB4A 3ELSA 1R21A 3UNNA 4JONA
chains in the Genus database with same CATH superfamily
5JEOA 1GXCA 2XXSA 3POAA 1YT5A 1DMZA 2I2FA 3DSHA 1Z0UA 4KU0D 5DHRA 5E50A 2EH0A 1FHRA 3VPYA 4V24A 5JERA 3T5PA 3VZCA 1Z0ZA 2BONA 3V8QA 2QVLA 5EJIA 5DHPA 1MZKA 1U0TA 3V7YA 4D9VA 1J4QA 2JQIA 2FF4A 4R9PA 2KKLA 4DY6A 1U7VB 1FHQA 3V8MA 1KHUA 3V8NA 3UMZA 1U7FA 3OUNA 2A0TA 1Y3HA 1G6GA 3VZDA 2JGRA 3ELVA 1QWTA 2I29A 2PIEA 5EJGA 1K3QA 3UV0A 4H87A 5EJHA 3GQSA 2CSWA 1LGQA 3KT9A 1LGPA 4JIWD 1UJXA 3V7WA 5JELA 3MDBA 5JEKA 3I0MA 1Y3IA 3I0NA 5DJOA 5BVIA 4WRRA 4A0EA 3GMJA 5C4VA 3UN0A 1UHTA 3AFOA 1MJSA 1G3GA 3V80A 2JKDA 3UOTA 5DHQA 5JEMA 2W3OA 2QV7A 1K2NA 3HUFA 2KB3A 2AFFA 3VA4A 3VZBA 4WERA 3HUEA 1J4PA 3UNMA 1K2MA 3S40A 1J2FA 1U7VA 1YJ5C 2JQLA 1KHXA 2I1WA 1G88A 4L02A 3V8PA 3DITA 1J4LA 1YGSA 2XT9B 2Q5FA 5DHUA 4EGXA 1DEVA 2KFUA 3V7UA 1YJMA 1MR1A 1U0RA 5A8IA 5DHTA 4QCJA 1DD1A 2I2DA 2LC1A 5EJFA 4A4YA 2P1RA 4JIVD 1K3JA 4G2SA 1MK2A 1J4OA 1WV3A 1Z0SA 2BRFA 2JPEA 2JQJA 1K3NA 2FEZA 1U7FB 2I2BA 3I6WA 3PO8A 1J4KA 2G1LA 3HX1A 1QU5A 3I6UA 4HAOA 4EJQA 3FM8A 1WLNA 3A77A 2I2CA 2I2AA 3VA1A 2KB4A 3ELSA 1R21A 3UNNA 1SUWA 4JONA 5DHSA 5JEJA 3V8RA 1ZOQA 3PFNA 2AN1A
chains in the Genus database with same CATH topology
5JEOA 1GXCA 2XXSA 3POAA 1DMZA 3DSHA 4KU0D 5E50A 2EH0A 1FHRA 3VPYA 4V24A 5JERA 3T5PA 3VZCA 2BONA 2QVLA 1MZKA 4D9VA 1J4QA 2JQIA 2FF4A 4R9PA 2KKLA 1U7VB 1FHQA 1KHUA 3UMZA 1U7FA 3OUNA 2A0TA 1G6GA 3VZDA 2JGRA 3ELVA 1QWTA 2PIEA 1K3QA 3UV0A 4H87A 3GQSA 2CSWA 3KT9A 1LGQA 1LGPA 4JIWD 1UJXA 5JELA 3MDBA 5JEKA 3I0MA 3I0NA 5DJOA 5BVIA 4WRRA 4A0EA 3GMJA 5C4VA 3UN0A 1UHTA 1MJSA 1G3GA 2JKDA 3UOTA 5JEMA 2W3OA 2QV7A 1K2NA 3HUFA 2KB3A 2AFFA 3VA4A 3VZBA 4WERA 3HUEA 1J4PA 3UNMA 1K2MA 3S40A 1J2FA 1U7VA 1YJ5C 2JQLA 1KHXA 4L02A 1G88A 3DITA 1J4LA 1YGSA 2XT9B 4EGXA 1DEVA 2KFUA 1YJMA 1MR1A 5A8IA 4QCJA 1DD1A 2LC1A 4A4YA 2P1RA 4JIVD 1K3JA 4G2SA 1MK2A 1J4OA 1WV3A 2BRFA 2JPEA 2JQJA 1K3NA 2FEZA 1U7FB 3I6WA 3PO8A 1J4KA 2G1LA 3HX1A 1QU5A 3I6UA 4EJQA 3FM8A 1WLNA 3A77A 3VA1A 2KB4A 3ELSA 1R21A 3UNNA 4JONA 5JEJA 1ZOQA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1GXC A;  3POA A;  1DMZ A;  5E50 A;  2EH0 A;  1FHR A;  3VPY A;  1MZK A;  4D9V A;  1J4Q A;  2JQI A;  2FF4 A;  2KKL A;  1FHQ A;  3UMZ A;  3OUN A;  2A0T A;  1G6G A;  3ELV A;  2PIE A;  1K3Q A;  3UV0 A;  4H87 A;  3GQS A;  2CSW A;  1LGQ A;  3KT9 A;  1LGP A;  1UJX A;  3MDB A;  3I0M A;  3I0N A;  5DJO A;  4A0E A;  3UN0 A;  1UHT A;  1G3G A;  2JKD A;  3UOT A;  2W3O A;  1K2N A;  3HUF A;  2KB3 A;  2AFF A;  3VA4 A;  3HUE A;  1J4P A;  3UNM A;  1K2M A;  1YJ5 C;  2JQL A;  1J4L A;  2XT9 B;  4EGX A;  2KFU A;  1YJM A;  5A8I A;  4QCJ A;  2LC1 A;  1K3J A;  4G2S A;  1WV3 A;  1J4O A;  2BRF A;  2JPE A;  2JQJ A;  1K3N A;  2FEZ A;  3I6W A;  3PO8 A;  1J4K A;  2G1L A;  4EJQ A;  1QU5 A;  3HX1 A;  3I6U A;  3FM8 A;  1WLN A;  3VA1 A;  2KB4 A;  3ELS A;  1R21 A;  3UNN A;  4JON A; 
#chains in the Genus database with same CATH topology
 5JEO A;  1GXC A;  2XXS A;  3POA A;  1YT5 A;  1DMZ A;  2I2F A;  3DSH A;  1Z0U A;  4KU0 D;  5DHR A;  5E50 A;  2EH0 A;  1FHR A;  3VPY A;  4V24 A;  5JER A;  3T5P A;  3VZC A;  1Z0Z A;  2BON A;  3V8Q A;  2QVL A;  5EJI A;  5DHP A;  1MZK A;  1U0T A;  3V7Y A;  4D9V A;  1J4Q A;  2JQI A;  2FF4 A;  4R9P A;  2KKL A;  4DY6 A;  1U7V B;  1FHQ A;  3V8M A;  1KHU A;  3V8N A;  3UMZ A;  1U7F A;  3OUN A;  2A0T A;  1Y3H A;  1G6G A;  3VZD A;  2JGR A;  3ELV A;  1QWT A;  2I29 A;  2PIE A;  5EJG A;  1K3Q A;  3UV0 A;  4H87 A;  5EJH A;  3GQS A;  2CSW A;  1LGQ A;  3KT9 A;  1LGP A;  4JIW D;  1UJX A;  3V7W A;  5JEL A;  3MDB A;  5JEK A;  3I0M A;  1Y3I A;  3I0N A;  5DJO A;  5BVI A;  4WRR A;  4A0E A;  3GMJ A;  5C4V A;  3UN0 A;  1UHT A;  3AFO A;  1MJS A;  1G3G A;  3V80 A;  2JKD A;  3UOT A;  5DHQ A;  5JEM A;  2W3O A;  2QV7 A;  1K2N A;  3HUF A;  2KB3 A;  2AFF A;  3VA4 A;  3VZB A;  4WER A;  3HUE A;  1J4P A;  3UNM A;  1K2M A;  3S40 A;  1J2F A;  1U7V A;  1YJ5 C;  2JQL A;  1KHX A;  2I1W A;  1G88 A;  4L02 A;  3V8P A;  3DIT A;  1J4L A;  1YGS A;  2XT9 B;  2Q5F A;  5DHU A;  4EGX A;  1DEV A;  2KFU A;  3V7U A;  1YJM A;  1MR1 A;  1U0R A;  5A8I A;  5DHT A;  4QCJ A;  1DD1 A;  2I2D A;  2LC1 A;  5EJF A;  4A4Y A;  2P1R A;  4JIV D;  1K3J A;  4G2S A;  1MK2 A;  1J4O A;  1WV3 A;  1Z0S A;  2BRF A;  2JPE A;  2JQJ A;  1K3N A;  2FEZ A;  1U7F B;  2I2B A;  3I6W A;  3PO8 A;  1J4K A;  2G1L A;  3HX1 A;  1QU5 A;  3I6U A;  4HAO A;  4EJQ A;  3FM8 A;  1WLN A;  3A77 A;  2I2C A;  2I2A A;  3VA1 A;  2KB4 A;  3ELS A;  1R21 A;  3UNN A;  1SUW A;  4JON A;  5DHS A;  5JEJ A;  3V8R A;  1ZOQ A;  3PFN A;  2AN1 A; 
#chains in the Genus database with same CATH homology
 5JEO A;  1GXC A;  2XXS A;  3POA A;  1DMZ A;  3DSH A;  4KU0 D;  5E50 A;  2EH0 A;  1FHR A;  3VPY A;  4V24 A;  5JER A;  3T5P A;  3VZC A;  2BON A;  2QVL A;  1MZK A;  4D9V A;  1J4Q A;  2JQI A;  2FF4 A;  4R9P A;  2KKL A;  1U7V B;  1FHQ A;  1KHU A;  3UMZ A;  1U7F A;  3OUN A;  2A0T A;  1G6G A;  3VZD A;  2JGR A;  3ELV A;  1QWT A;  2PIE A;  1K3Q A;  3UV0 A;  4H87 A;  3GQS A;  2CSW A;  3KT9 A;  1LGQ A;  1LGP A;  4JIW D;  1UJX A;  5JEL A;  3MDB A;  5JEK A;  3I0M A;  3I0N A;  5DJO A;  5BVI A;  4WRR A;  4A0E A;  3GMJ A;  5C4V A;  3UN0 A;  1UHT A;  1MJS A;  1G3G A;  2JKD A;  3UOT A;  5JEM A;  2W3O A;  2QV7 A;  1K2N A;  3HUF A;  2KB3 A;  2AFF A;  3VA4 A;  3VZB A;  4WER A;  3HUE A;  1J4P A;  3UNM A;  1K2M A;  3S40 A;  1J2F A;  1U7V A;  1YJ5 C;  2JQL A;  1KHX A;  4L02 A;  1G88 A;  3DIT A;  1J4L A;  1YGS A;  2XT9 B;  4EGX A;  1DEV A;  2KFU A;  1YJM A;  1MR1 A;  5A8I A;  4QCJ A;  1DD1 A;  2LC1 A;  4A4Y A;  2P1R A;  4JIV D;  1K3J A;  4G2S A;  1MK2 A;  1J4O A;  1WV3 A;  2BRF A;  2JPE A;  2JQJ A;  1K3N A;  2FEZ A;  1U7F B;  3I6W A;  3PO8 A;  1J4K A;  2G1L A;  3HX1 A;  1QU5 A;  3I6U A;  4EJQ A;  3FM8 A;  1WLN A;  3A77 A;  3VA1 A;  2KB4 A;  3ELS A;  1R21 A;  3UNN A;  4JON A;  5JEJ A;  1ZOQ A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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