1LGQA

Crystal structure of the fha domain of the chfr mitotic checkpoint protein
Total Genus 14
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
14
sequence length
112
structure length
112
Chain Sequence
MQPWGRLLRLGAEEGEPHVLLRKREWTIGRRRGCDLSFPSNKLVSGDHCRIVVDEKSGQVTLEDTSTSGTVINKLKVVKKQTCPLQTGDVIYLVYRKNEPEHNVAYLYESLS
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Crystal structure of the FHA domain of the Chfr mitotic checkpoint protein and its complex with tungstate.
pubmed doi rcsb
molecule tags Cell cycle
source organism Homo sapiens
molecule keywords cell cycle checkpoint protein CHFR
total genus 14
structure length 112
sequence length 112
chains with identical sequence B
ec nomenclature ec 2.3.2.27: RING-type E3 ubiquitin transferase.
pdb deposition date 2002-04-16

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00498 FHA FHA domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.60.200.20 Mainly Beta Sandwich Tumour Suppressor Smad4 Tumour Suppressor Smad4 1lgqA00
1WLNA 1FHRA 4A0EA 3UOTA 1UJXA 2FF4A 2JKDA 3OUNA 2W3OA 4QCJA 1J4KA 2CSWA 1MZKA 1K2MA 3ELSA 1UHTA 3VPYA 2JQIA 2FEZA 3I6UA 3UN0A 4H87A 2LC1A 1K3NA 3I0MA 2JQLA 1QU5A 2KFUA 3UNMA 4D9VA 1R21A 3POAA 2G1LA 5DJOA 1K3JA 3MDBA 2AFFA 2JQJA 3VA4A 3PO8A 3UMZA 2PIEA 3I0NA 3UV0A 3HX1A 2BRFA 1GXCA 3HUFA 2A0TA 5A8IA 3UNNA 1J4QA 3VA1A 3I6WA 1G3GA 1K3QA 2EH0A 1J4OA 1LGPA 1WV3A 1K2NA 1YJMA 3HUEA 4EJQA 2JPEA 3FM8A 4JONA 2KB3A 2KB4A 2KKLA 1YJ5C 3GQSA 1G6GA 4EGXA 3ELVA 1LGQA 1J4PA 2XT9B 1DMZA 3KT9A 1J4LA 4G2SA 1FHQA 5E50A
chains in the Genus database with same CATH superfamily
3AFOA 1Z0ZA 4WRRA 1WLNA 1FHRA 4A0EA 3UOTA 5JEOA 1G88A 1UJXA 2FF4A 5EJHA 2JKDA 3OUNA 2W3OA 3V8PA 3V8RA 4QCJA 1J4KA 1Y3IA 1YGSA 2CSWA 3S40A 3VZCA 1MZKA 4JIWD 3DSHA 1K2MA 3ELSA 5JEJA 1UHTA 2AN1A 4L02A 4WERA 1U7VB 3VPYA 2JQIA 1U7VA 2I2CA 2I29A 5DHPA 2FEZA 3I6UA 2I2FA 5JELA 3UN0A 4DY6A 4H87A 2LC1A 2BONA 3V8QA 1Z0UA 5EJGA 1K3NA 5DHUA 3I0MA 1MK2A 2JQLA 3V7YA 1U7FB 1QU5A 1U7FA 2KFUA 5JERA 3UNMA 5DHRA 3T5PA 3PFNA 4D9VA 1SUWA 1R21A 1U0RA 3V7UA 3POAA 2G1LA 5EJIA 5EJFA 1Y3HA 5DJOA 1K3JA 3MDBA 1ZOQA 5C4VA 2QVLA 2QV7A 2AFFA 2JQJA 3VA4A 2I2AA 1J2FA 2XXSA 2JGRA 3PO8A 3UMZA 4R9PA 1U0TA 1Z0SA 2PIEA 3V7WA 3I0NA 1QWTA 3UV0A 3HX1A 2BRFA 4KU0D 5BVIA 1GXCA 3HUFA 1MR1A 5DHSA 3V8NA 2A0TA 2Q5FA 5DHTA 5A8IA 3UNNA 1J4QA 5DHQA 3VA1A 3I6WA 1G3GA 3VZBA 3V80A 1K3QA 2EH0A 1J4OA 4V24A 1LGPA 4A4YA 1WV3A 1K2NA 4HAOA 1DD1A 1DEVA 2I1WA 2I2DA 1YJMA 3HUEA 4EJQA 5JEKA 3DITA 2I2BA 2JPEA 3FM8A 4JONA 5JEMA 2KB3A 3GMJA 2KB4A 2KKLA 1YJ5C 2P1RA 3GQSA 3VZDA 1G6GA 4EGXA 3ELVA 1MJSA 3A77A 3V8MA 1LGQA 1YT5A 1J4PA 2XT9B 1DMZA 3KT9A 1J4LA 1KHUA 4G2SA 4JIVD 1FHQA 5E50A 1KHXA
chains in the Genus database with same CATH topology
4WRRA 1WLNA 1FHRA 4A0EA 3UOTA 5JEOA 1G88A 1UJXA 2FF4A 2JKDA 3OUNA 2W3OA 4QCJA 1J4KA 1YGSA 2CSWA 3S40A 3VZCA 1MZKA 4JIWD 3DSHA 1K2MA 3ELSA 5JEJA 1UHTA 4L02A 4WERA 1U7VB 3VPYA 2JQIA 1U7VA 2FEZA 3I6UA 5JELA 3UN0A 4H87A 2LC1A 2BONA 1K3NA 3I0MA 1MK2A 2JQLA 1U7FB 1QU5A 1U7FA 2KFUA 5JERA 3UNMA 3T5PA 4D9VA 1R21A 3POAA 2G1LA 5DJOA 1K3JA 3MDBA 1ZOQA 5C4VA 2QVLA 2QV7A 2AFFA 2JQJA 3VA4A 1J2FA 2XXSA 2JGRA 3PO8A 3UMZA 4R9PA 2PIEA 3I0NA 1QWTA 3UV0A 3HX1A 2BRFA 4KU0D 5BVIA 1GXCA 3HUFA 1MR1A 2A0TA 5A8IA 3UNNA 1J4QA 3VA1A 3I6WA 1G3GA 3VZBA 1K3QA 2EH0A 1J4OA 4V24A 1LGPA 4A4YA 1WV3A 1K2NA 1DD1A 1DEVA 1YJMA 3HUEA 4EJQA 5JEKA 3DITA 2JPEA 3FM8A 4JONA 5JEMA 2KB3A 3GMJA 2KB4A 2KKLA 1YJ5C 2P1RA 3GQSA 3VZDA 1G6GA 4EGXA 3ELVA 1MJSA 3A77A 1LGQA 1J4PA 2XT9B 1DMZA 3KT9A 1J4LA 1KHUA 4G2SA 4JIVD 1FHQA 5E50A 1KHXA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1WLN A;  1FHR A;  4A0E A;  3UOT A;  1UJX A;  2FF4 A;  2JKD A;  3OUN A;  2W3O A;  4QCJ A;  1J4K A;  2CSW A;  1MZK A;  1K2M A;  3ELS A;  1UHT A;  3VPY A;  2JQI A;  2FEZ A;  3I6U A;  3UN0 A;  4H87 A;  2LC1 A;  1K3N A;  3I0M A;  2JQL A;  1QU5 A;  2KFU A;  3UNM A;  4D9V A;  1R21 A;  3POA A;  2G1L A;  5DJO A;  1K3J A;  3MDB A;  2AFF A;  2JQJ A;  3VA4 A;  3PO8 A;  3UMZ A;  2PIE A;  3I0N A;  3UV0 A;  3HX1 A;  2BRF A;  1GXC A;  3HUF A;  2A0T A;  5A8I A;  3UNN A;  1J4Q A;  3VA1 A;  3I6W A;  1G3G A;  1K3Q A;  2EH0 A;  1J4O A;  1LGP A;  1WV3 A;  1K2N A;  1YJM A;  3HUE A;  4EJQ A;  2JPE A;  3FM8 A;  4JON A;  2KB3 A;  2KB4 A;  2KKL A;  1YJ5 C;  3GQS A;  1G6G A;  4EGX A;  3ELV A;  1LGQ A;  1J4P A;  2XT9 B;  1DMZ A;  3KT9 A;  1J4L A;  4G2S A;  1FHQ A;  5E50 A; 
#chains in the Genus database with same CATH topology
 3AFO A;  1Z0Z A;  4WRR A;  1WLN A;  1FHR A;  4A0E A;  3UOT A;  5JEO A;  1G88 A;  1UJX A;  2FF4 A;  5EJH A;  2JKD A;  3OUN A;  2W3O A;  3V8P A;  3V8R A;  4QCJ A;  1J4K A;  1Y3I A;  1YGS A;  2CSW A;  3S40 A;  3VZC A;  1MZK A;  4JIW D;  3DSH A;  1K2M A;  3ELS A;  5JEJ A;  1UHT A;  2AN1 A;  4L02 A;  4WER A;  1U7V B;  3VPY A;  2JQI A;  1U7V A;  2I2C A;  2I29 A;  5DHP A;  2FEZ A;  3I6U A;  2I2F A;  5JEL A;  3UN0 A;  4DY6 A;  4H87 A;  2LC1 A;  2BON A;  3V8Q A;  1Z0U A;  5EJG A;  1K3N A;  5DHU A;  3I0M A;  1MK2 A;  2JQL A;  3V7Y A;  1U7F B;  1QU5 A;  1U7F A;  2KFU A;  5JER A;  3UNM A;  5DHR A;  3T5P A;  3PFN A;  4D9V A;  1SUW A;  1R21 A;  1U0R A;  3V7U A;  3POA A;  2G1L A;  5EJI A;  5EJF A;  1Y3H A;  5DJO A;  1K3J A;  3MDB A;  1ZOQ A;  5C4V A;  2QVL A;  2QV7 A;  2AFF A;  2JQJ A;  3VA4 A;  2I2A A;  1J2F A;  2XXS A;  2JGR A;  3PO8 A;  3UMZ A;  4R9P A;  1U0T A;  1Z0S A;  2PIE A;  3V7W A;  3I0N A;  1QWT A;  3UV0 A;  3HX1 A;  2BRF A;  4KU0 D;  5BVI A;  1GXC A;  3HUF A;  1MR1 A;  5DHS A;  3V8N A;  2A0T A;  2Q5F A;  5DHT A;  5A8I A;  3UNN A;  1J4Q A;  5DHQ A;  3VA1 A;  3I6W A;  1G3G A;  3VZB A;  3V80 A;  1K3Q A;  2EH0 A;  1J4O A;  4V24 A;  1LGP A;  4A4Y A;  1WV3 A;  1K2N A;  4HAO A;  1DD1 A;  1DEV A;  2I1W A;  2I2D A;  1YJM A;  3HUE A;  4EJQ A;  5JEK A;  3DIT A;  2I2B A;  2JPE A;  3FM8 A;  4JON A;  5JEM A;  2KB3 A;  3GMJ A;  2KB4 A;  2KKL A;  1YJ5 C;  2P1R A;  3GQS A;  3VZD A;  1G6G A;  4EGX A;  3ELV A;  1MJS A;  3A77 A;  3V8M A;  1LGQ A;  1YT5 A;  1J4P A;  2XT9 B;  1DMZ A;  3KT9 A;  1J4L A;  1KHU A;  4G2S A;  4JIV D;  1FHQ A;  5E50 A;  1KHX A; 
#chains in the Genus database with same CATH homology
 4WRR A;  1WLN A;  1FHR A;  4A0E A;  3UOT A;  5JEO A;  1G88 A;  1UJX A;  2FF4 A;  2JKD A;  3OUN A;  2W3O A;  4QCJ A;  1J4K A;  1YGS A;  2CSW A;  3S40 A;  3VZC A;  1MZK A;  4JIW D;  3DSH A;  1K2M A;  3ELS A;  5JEJ A;  1UHT A;  4L02 A;  4WER A;  1U7V B;  3VPY A;  2JQI A;  1U7V A;  2FEZ A;  3I6U A;  5JEL A;  3UN0 A;  4H87 A;  2LC1 A;  2BON A;  1K3N A;  3I0M A;  1MK2 A;  2JQL A;  1U7F B;  1QU5 A;  1U7F A;  2KFU A;  5JER A;  3UNM A;  3T5P A;  4D9V A;  1R21 A;  3POA A;  2G1L A;  5DJO A;  1K3J A;  3MDB A;  1ZOQ A;  5C4V A;  2QVL A;  2QV7 A;  2AFF A;  2JQJ A;  3VA4 A;  1J2F A;  2XXS A;  2JGR A;  3PO8 A;  3UMZ A;  4R9P A;  2PIE A;  3I0N A;  1QWT A;  3UV0 A;  3HX1 A;  2BRF A;  4KU0 D;  5BVI A;  1GXC A;  3HUF A;  1MR1 A;  2A0T A;  5A8I A;  3UNN A;  1J4Q A;  3VA1 A;  3I6W A;  1G3G A;  3VZB A;  1K3Q A;  2EH0 A;  1J4O A;  4V24 A;  1LGP A;  4A4Y A;  1WV3 A;  1K2N A;  1DD1 A;  1DEV A;  1YJM A;  3HUE A;  4EJQ A;  5JEK A;  3DIT A;  2JPE A;  3FM8 A;  4JON A;  5JEM A;  2KB3 A;  3GMJ A;  2KB4 A;  2KKL A;  1YJ5 C;  2P1R A;  3GQS A;  3VZD A;  1G6G A;  4EGX A;  3ELV A;  1MJS A;  3A77 A;  1LGQ A;  1J4P A;  2XT9 B;  1DMZ A;  3KT9 A;  1J4L A;  1KHU A;  4G2S A;  4JIV D;  1FHQ A;  5E50 A;  1KHX A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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