2A0TA

Nmr structure of the fha1 domain of rad53 in complex with a biological relevant phosphopeptide derived from madt1
Total Genus 24
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
24
sequence length
151
structure length
151
Chain Sequence
ATQRFLIEKFSQEQIGENIVCRVICTTGQIPIRDLSADISQVLKEKRSIKKVWTFGRNPACDYHLGNISRLSNKHFQILLGEDGNLLLNDISTNGTWLNGQKVEKNSNQLLSQGDEITVGVGVESDILSLVIFINDKFKQCLEQNKVDRIR
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title FHA Domain-Ligand Interactions: Importance of Integrating Chemical and Biological Approaches
pubmed doi rcsb
molecule tags Transferase
source organism Saccharomyces cerevisiae
molecule keywords Serine/threonine-protein kinase RAD53
total genus 24
structure length 151
sequence length 151
ec nomenclature ec 2.7.12.1: Dual-specificity kinase.
pdb deposition date 2005-06-16

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00498 FHA FHA domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.60.200.20 Mainly Beta Sandwich Tumour Suppressor Smad4 Tumour Suppressor Smad4 2a0tA00
3HUEA 1UJXA 2KKLA 1J4QA 1G3GA 2CSWA 1K2NA 3POAA 3UN0A 4G2SA 3UNNA 2G1LA 4A0EA 3I0MA 2FEZA 1J4KA 2AFFA 1UHTA 1R21A 3VA4A 3GQSA 3HX1A 1WLNA 2PIEA 1WV3A 2JQIA 3I0NA 1QU5A 3I6UA 1GXCA 3PO8A 4D9VA 4H87A 1G6GA 3MDBA 2KB3A 2JKDA 2KB4A 1LGQA 1DMZA 4EJQA 1YJMA 2BRFA 3UV0A 3I6WA 1K3QA 3UOTA 2W3OA 4EGXA 3ELSA 1J4PA 2LC1A 2JQJA 2JPEA 5DJOA 3UNMA 2EH0A 1YJ5C 2A0TA 1FHQA 1LGPA 3KT9A 3ELVA 1FHRA 4QCJA 3VA1A 2FF4A 5A8IA 1K3NA 1J4LA 1MZKA 3UMZA 3VPYA 5E50A 3FM8A 2XT9B 1K2MA 3OUNA 1J4OA 3HUFA 4JONA 2KFUA 2JQLA 1K3JA
chains in the Genus database with same CATH superfamily
3HUEA 5DHPA 5JEOA 4R9PA 1MK2A 1UJXA 1Z0SA 2KKLA 1J4QA 1YGSA 1KHUA 1G3GA 1G88A 1ZOQA 2I2BA 1DD1A 2CSWA 4WERA 1U7VB 2Q5FA 1K2NA 3POAA 1Z0UA 5DHTA 4JIWD 3UN0A 4G2SA 3UNNA 2G1LA 4A0EA 3I0MA 2FEZA 1U7FA 1J4KA 2AFFA 2P1RA 1UHTA 5JELA 5JEMA 4A4YA 1R21A 5EJFA 4V24A 3VA4A 5C4VA 3GQSA 3HX1A 1WLNA 2I29A 1SUWA 2PIEA 1WV3A 5EJIA 5DHQA 1U0RA 2I2CA 2JQIA 3I0NA 1U7FB 1J2FA 1QU5A 3I6UA 3V8PA 1GXCA 1QWTA 3V8MA 3PO8A 4D9VA 3DSHA 5DHRA 5JERA 4H87A 1G6GA 1Y3HA 3V7UA 3MDBA 4KU0D 2I2AA 3T5PA 3GMJA 2KB3A 3V8RA 2JKDA 3V80A 5EJHA 1KHXA 1Y3IA 2AN1A 3S40A 2KB4A 1YT5A 1LGQA 1DMZA 3VZDA 3VZCA 4EJQA 1K3JA 1YJMA 2BRFA 3UV0A 3I6WA 4L02A 1K3QA 3V8QA 2JGRA 1MJSA 2XXSA 3UOTA 2W3OA 4EGXA 3ELSA 5DHSA 1J4PA 2LC1A 2I2FA 2JQJA 1MR1A 2JPEA 5DJOA 3UNMA 2EH0A 1YJ5C 2A0TA 1FHQA 4WRRA 1Z0ZA 1LGPA 3KT9A 1DEVA 3ELVA 5JEKA 1FHRA 4QCJA 3VA1A 3A77A 5DHUA 5EJGA 3V7WA 3V8NA 2FF4A 1U0TA 5A8IA 1K3NA 1J4LA 1MZKA 2BONA 4JIVD 2I2DA 3UMZA 3VPYA 3V7YA 5E50A 3FM8A 5BVIA 2XT9B 1K2MA 2QV7A 2QVLA 4DY6A 3OUNA 3PFNA 1J4OA 3AFOA 3VZBA 3HUFA 1U7VA 3DITA 4JONA 2I1WA 2KFUA 5JEJA 2JQLA 4HAOA
chains in the Genus database with same CATH topology
3HUEA 5JEOA 4R9PA 1MK2A 1UJXA 2KKLA 1J4QA 1YGSA 1KHUA 1G3GA 1G88A 1ZOQA 1DD1A 2CSWA 4WERA 1U7VB 1K2NA 3POAA 4JIWD 3UN0A 4G2SA 3UNNA 2G1LA 4A0EA 3I0MA 2FEZA 1U7FA 1J4KA 2AFFA 2P1RA 1UHTA 5JELA 5JEMA 4A4YA 1R21A 4V24A 3VA4A 5C4VA 3GQSA 3HX1A 1WLNA 2PIEA 1WV3A 2JQIA 3I0NA 1U7FB 1J2FA 1QU5A 3I6UA 1GXCA 1QWTA 3PO8A 4D9VA 3DSHA 5JERA 4H87A 1G6GA 3MDBA 4KU0D 3T5PA 3GMJA 2KB3A 2JKDA 1KHXA 3S40A 2KB4A 1LGQA 1DMZA 3VZDA 3VZCA 4EJQA 1YJMA 2BRFA 3UV0A 3I6WA 4L02A 1K3QA 2JGRA 1MJSA 2XXSA 3UOTA 2W3OA 4EGXA 3ELSA 1J4PA 2LC1A 2JQJA 1MR1A 2JPEA 5DJOA 3UNMA 2EH0A 1YJ5C 2A0TA 1FHQA 4WRRA 1LGPA 3KT9A 1DEVA 3ELVA 5JEKA 1FHRA 4QCJA 3VA1A 3A77A 2FF4A 5A8IA 1K3NA 1J4LA 1MZKA 2BONA 4JIVD 3UMZA 3VPYA 5E50A 3FM8A 5BVIA 2XT9B 1K2MA 2QV7A 2QVLA 3OUNA 1J4OA 3VZBA 3HUFA 1U7VA 3DITA 4JONA 2KFUA 5JEJA 2JQLA 1K3JA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3HUE A;  1UJX A;  2KKL A;  1J4Q A;  1G3G A;  2CSW A;  1K2N A;  3POA A;  3UN0 A;  4G2S A;  3UNN A;  2G1L A;  4A0E A;  3I0M A;  2FEZ A;  1J4K A;  2AFF A;  1UHT A;  1R21 A;  3VA4 A;  3GQS A;  3HX1 A;  1WLN A;  2PIE A;  1WV3 A;  2JQI A;  3I0N A;  1QU5 A;  3I6U A;  1GXC A;  3PO8 A;  4D9V A;  4H87 A;  1G6G A;  3MDB A;  2KB3 A;  2JKD A;  2KB4 A;  1LGQ A;  1DMZ A;  4EJQ A;  1YJM A;  2BRF A;  3UV0 A;  3I6W A;  1K3Q A;  3UOT A;  2W3O A;  4EGX A;  3ELS A;  1J4P A;  2LC1 A;  2JQJ A;  2JPE A;  5DJO A;  3UNM A;  2EH0 A;  1YJ5 C;  2A0T A;  1FHQ A;  1LGP A;  3KT9 A;  3ELV A;  1FHR A;  4QCJ A;  3VA1 A;  2FF4 A;  5A8I A;  1K3N A;  1J4L A;  1MZK A;  3UMZ A;  3VPY A;  5E50 A;  3FM8 A;  2XT9 B;  1K2M A;  3OUN A;  1J4O A;  3HUF A;  4JON A;  2KFU A;  2JQL A;  1K3J A; 
#chains in the Genus database with same CATH topology
 3HUE A;  5DHP A;  5JEO A;  4R9P A;  1MK2 A;  1UJX A;  1Z0S A;  2KKL A;  1J4Q A;  1YGS A;  1KHU A;  1G3G A;  1G88 A;  1ZOQ A;  2I2B A;  1DD1 A;  2CSW A;  4WER A;  1U7V B;  2Q5F A;  1K2N A;  3POA A;  1Z0U A;  5DHT A;  4JIW D;  3UN0 A;  4G2S A;  3UNN A;  2G1L A;  4A0E A;  3I0M A;  2FEZ A;  1U7F A;  1J4K A;  2AFF A;  2P1R A;  1UHT A;  5JEL A;  5JEM A;  4A4Y A;  1R21 A;  5EJF A;  4V24 A;  3VA4 A;  5C4V A;  3GQS A;  3HX1 A;  1WLN A;  2I29 A;  1SUW A;  2PIE A;  1WV3 A;  5EJI A;  5DHQ A;  1U0R A;  2I2C A;  2JQI A;  3I0N A;  1U7F B;  1J2F A;  1QU5 A;  3I6U A;  3V8P A;  1GXC A;  1QWT A;  3V8M A;  3PO8 A;  4D9V A;  3DSH A;  5DHR A;  5JER A;  4H87 A;  1G6G A;  1Y3H A;  3V7U A;  3MDB A;  4KU0 D;  2I2A A;  3T5P A;  3GMJ A;  2KB3 A;  3V8R A;  2JKD A;  3V80 A;  5EJH A;  1KHX A;  1Y3I A;  2AN1 A;  3S40 A;  2KB4 A;  1YT5 A;  1LGQ A;  1DMZ A;  3VZD A;  3VZC A;  4EJQ A;  1K3J A;  1YJM A;  2BRF A;  3UV0 A;  3I6W A;  4L02 A;  1K3Q A;  3V8Q A;  2JGR A;  1MJS A;  2XXS A;  3UOT A;  2W3O A;  4EGX A;  3ELS A;  5DHS A;  1J4P A;  2LC1 A;  2I2F A;  2JQJ A;  1MR1 A;  2JPE A;  5DJO A;  3UNM A;  2EH0 A;  1YJ5 C;  2A0T A;  1FHQ A;  4WRR A;  1Z0Z A;  1LGP A;  3KT9 A;  1DEV A;  3ELV A;  5JEK A;  1FHR A;  4QCJ A;  3VA1 A;  3A77 A;  5DHU A;  5EJG A;  3V7W A;  3V8N A;  2FF4 A;  1U0T A;  5A8I A;  1K3N A;  1J4L A;  1MZK A;  2BON A;  4JIV D;  2I2D A;  3UMZ A;  3VPY A;  3V7Y A;  5E50 A;  3FM8 A;  5BVI A;  2XT9 B;  1K2M A;  2QV7 A;  2QVL A;  4DY6 A;  3OUN A;  3PFN A;  1J4O A;  3AFO A;  3VZB A;  3HUF A;  1U7V A;  3DIT A;  4JON A;  2I1W A;  2KFU A;  5JEJ A;  2JQL A;  4HAO A; 
#chains in the Genus database with same CATH homology
 3HUE A;  5JEO A;  4R9P A;  1MK2 A;  1UJX A;  2KKL A;  1J4Q A;  1YGS A;  1KHU A;  1G3G A;  1G88 A;  1ZOQ A;  1DD1 A;  2CSW A;  4WER A;  1U7V B;  1K2N A;  3POA A;  4JIW D;  3UN0 A;  4G2S A;  3UNN A;  2G1L A;  4A0E A;  3I0M A;  2FEZ A;  1U7F A;  1J4K A;  2AFF A;  2P1R A;  1UHT A;  5JEL A;  5JEM A;  4A4Y A;  1R21 A;  4V24 A;  3VA4 A;  5C4V A;  3GQS A;  3HX1 A;  1WLN A;  2PIE A;  1WV3 A;  2JQI A;  3I0N A;  1U7F B;  1J2F A;  1QU5 A;  3I6U A;  1GXC A;  1QWT A;  3PO8 A;  4D9V A;  3DSH A;  5JER A;  4H87 A;  1G6G A;  3MDB A;  4KU0 D;  3T5P A;  3GMJ A;  2KB3 A;  2JKD A;  1KHX A;  3S40 A;  2KB4 A;  1LGQ A;  1DMZ A;  3VZD A;  3VZC A;  4EJQ A;  1YJM A;  2BRF A;  3UV0 A;  3I6W A;  4L02 A;  1K3Q A;  2JGR A;  1MJS A;  2XXS A;  3UOT A;  2W3O A;  4EGX A;  3ELS A;  1J4P A;  2LC1 A;  2JQJ A;  1MR1 A;  2JPE A;  5DJO A;  3UNM A;  2EH0 A;  1YJ5 C;  2A0T A;  1FHQ A;  4WRR A;  1LGP A;  3KT9 A;  1DEV A;  3ELV A;  5JEK A;  1FHR A;  4QCJ A;  3VA1 A;  3A77 A;  2FF4 A;  5A8I A;  1K3N A;  1J4L A;  1MZK A;  2BON A;  4JIV D;  3UMZ A;  3VPY A;  5E50 A;  3FM8 A;  5BVI A;  2XT9 B;  1K2M A;  2QV7 A;  2QVL A;  3OUN A;  1J4O A;  3VZB A;  3HUF A;  1U7V A;  3DIT A;  4JON A;  2KFU A;  5JEJ A;  2JQL A;  1K3J A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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