2A0TA

Nmr structure of the fha1 domain of rad53 in complex with a biological relevant phosphopeptide derived from madt1
Total Genus 24
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
24
sequence length
151
structure length
151
Chain Sequence
ATQRFLIEKFSQEQIGENIVCRVICTTGQIPIRDLSADISQVLKEKRSIKKVWTFGRNPACDYHLGNISRLSNKHFQILLGEDGNLLLNDISTNGTWLNGQKVEKNSNQLLSQGDEITVGVGVESDILSLVIFINDKFKQCLEQNKVDRIR
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title FHA Domain-Ligand Interactions: Importance of Integrating Chemical and Biological Approaches
pubmed doi rcsb
molecule tags Transferase
source organism Saccharomyces cerevisiae
molecule keywords Serine/threonine-protein kinase RAD53
total genus 24
structure length 151
sequence length 151
ec nomenclature ec 2.7.12.1: Dual-specificity kinase.
pdb deposition date 2005-06-16

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00498 FHA FHA domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.60.200.20 Mainly Beta Sandwich Tumour Suppressor Smad4 Tumour Suppressor Smad4 2a0tA00
3PO8A 1K2MA 1G3GA 1DMZA 1GXCA 3GQSA 2LC1A 3ELVA 3KT9A 2BRFA 2JQIA 2JKDA 1UJXA 3UNMA 3HUFA 1LGPA 2KB3A 3UV0A 3HX1A 3I0MA 3UN0A 3VA1A 1YJMA 1FHRA 2AFFA 4QCJA 5A8IA 3UOTA 2JPEA 1R21A 3ELSA 2KKLA 1K3NA 1J4OA 3POAA 2XT9B 1J4QA 3UNNA 3OUNA 1WLNA 4H87A 1LGQA 1G6GA 2G1LA 2W3OA 2JQJA 2JQLA 1UHTA 3I6UA 2FF4A 3I6WA 2FEZA 2A0TA 4A0EA 4EGXA 5E50A 2PIEA 3HUEA 5DJOA 3UMZA 1MZKA 4JONA 1J4PA 3FM8A 1J4KA 1YJ5C 4G2SA 4EJQA 1FHQA 1K3JA 1K3QA 2KFUA 3I0NA 1K2NA 3VA4A 3VPYA 4D9VA 1J4LA 1WV3A 3MDBA 2KB4A 2CSWA 2EH0A 1QU5A
chains in the Genus database with same CATH superfamily
3PO8A 3AFOA 5C4VA 1K2MA 1G3GA 1DMZA 1GXCA 2I2FA 3GQSA 3GMJA 1KHXA 4HAOA 2LC1A 1Y3IA 3ELVA 3KT9A 3VZBA 2I2CA 4DY6A 3T5PA 4WERA 5BVIA 2BRFA 2JQIA 4JIVD 5DHPA 3V8RA 2JKDA 1U7FB 5DHSA 1J2FA 1UJXA 3UNMA 2BONA 3V8QA 5JEMA 1LGPA 3HUFA 2KB3A 2QVLA 3UV0A 3HX1A 2QV7A 3I0MA 3UN0A 5EJHA 1U7VB 1YJMA 3VA1A 1FHRA 1Z0SA 2AFFA 4QCJA 2I2DA 5A8IA 1DEVA 3UOTA 1U0TA 2JPEA 5DHQA 3VZCA 2P1RA 4V24A 1MJSA 5JELA 1R21A 1MR1A 4JIWD 4WRRA 3ELSA 2KKLA 2I1WA 2I2AA 2AN1A 1J4OA 1K3NA 3POAA 1YGSA 2XT9B 1J4QA 5JEOA 3UNNA 3OUNA 5JEJA 2I29A 1WLNA 3DSHA 4H87A 3V7WA 1LGQA 5DHUA 1G6GA 5DHRA 4KU0D 4L02A 2G1LA 2W3OA 2JQJA 2JQLA 1UHTA 1G88A 3I6UA 3V7UA 2FF4A 3I6WA 2FEZA 5EJIA 1U7VA 2A0TA 2JGRA 4A0EA 4EGXA 5E50A 2PIEA 3VZDA 3HUEA 5DJOA 1KHUA 3UMZA 1MZKA 4JONA 5EJGA 5EJFA 3V8NA 2I2BA 5DHTA 3DITA 1J4PA 1YT5A 1ZOQA 3V8PA 4A4YA 3FM8A 1MK2A 4R9PA 1J4KA 1YJ5C 3PFNA 1SUWA 3A77A 1U7FA 1Y3HA 1Z0ZA 3S40A 4G2SA 4EJQA 1FHQA 1K3JA 2XXSA 2Q5FA 5JERA 1K3QA 2KFUA 3V7YA 3I0NA 1K2NA 1Z0UA 3VA4A 5JEKA 3VPYA 1QWTA 4D9VA 1U0RA 1DD1A 1J4LA 1WV3A 3V8MA 3MDBA 3V80A 2KB4A 2CSWA 2EH0A 1QU5A
chains in the Genus database with same CATH topology
3PO8A 5C4VA 1K2MA 1G3GA 1DMZA 1GXCA 3GQSA 3GMJA 1KHXA 2LC1A 3ELVA 3KT9A 3VZBA 3T5PA 4WERA 5BVIA 2BRFA 2JQIA 4JIVD 2JKDA 1U7FB 1J2FA 1UJXA 3UNMA 2BONA 5JEMA 3HUFA 1LGPA 2KB3A 2QVLA 3UV0A 3HX1A 2QV7A 3I0MA 3UN0A 3VA1A 1U7VB 1YJMA 1FHRA 2AFFA 4QCJA 5A8IA 1DEVA 3UOTA 2JPEA 3VZCA 2P1RA 4V24A 1MJSA 5JELA 1R21A 1MR1A 4JIWD 4WRRA 3ELSA 2KKLA 1K3NA 1J4OA 3POAA 1YGSA 2XT9B 1J4QA 5JEOA 3UNNA 3OUNA 5JEJA 3DSHA 1WLNA 4H87A 1LGQA 1G6GA 4KU0D 4L02A 2G1LA 2W3OA 2JQJA 2JQLA 1UHTA 1G88A 3I6UA 2FF4A 3I6WA 2FEZA 1U7VA 2A0TA 2JGRA 4A0EA 4EGXA 5E50A 2PIEA 3VZDA 3HUEA 5DJOA 1KHUA 3UMZA 1MZKA 4JONA 3DITA 1J4PA 1ZOQA 4A4YA 3FM8A 1MK2A 4R9PA 1J4KA 1YJ5C 3A77A 1U7FA 3S40A 4G2SA 4EJQA 1FHQA 1K3JA 2XXSA 5JERA 1K3QA 2KFUA 3I0NA 1K2NA 3VA4A 5JEKA 3VPYA 1QWTA 4D9VA 1DD1A 1J4LA 1WV3A 3MDBA 2KB4A 2CSWA 2EH0A 1QU5A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3PO8 A;  1K2M A;  1G3G A;  1DMZ A;  1GXC A;  3GQS A;  2LC1 A;  3ELV A;  3KT9 A;  2BRF A;  2JQI A;  2JKD A;  1UJX A;  3UNM A;  3HUF A;  1LGP A;  2KB3 A;  3UV0 A;  3HX1 A;  3I0M A;  3UN0 A;  3VA1 A;  1YJM A;  1FHR A;  2AFF A;  4QCJ A;  5A8I A;  3UOT A;  2JPE A;  1R21 A;  3ELS A;  2KKL A;  1K3N A;  1J4O A;  3POA A;  2XT9 B;  1J4Q A;  3UNN A;  3OUN A;  1WLN A;  4H87 A;  1LGQ A;  1G6G A;  2G1L A;  2W3O A;  2JQJ A;  2JQL A;  1UHT A;  3I6U A;  2FF4 A;  3I6W A;  2FEZ A;  2A0T A;  4A0E A;  4EGX A;  5E50 A;  2PIE A;  3HUE A;  5DJO A;  3UMZ A;  1MZK A;  4JON A;  1J4P A;  3FM8 A;  1J4K A;  1YJ5 C;  4G2S A;  4EJQ A;  1FHQ A;  1K3J A;  1K3Q A;  2KFU A;  3I0N A;  1K2N A;  3VA4 A;  3VPY A;  4D9V A;  1J4L A;  1WV3 A;  3MDB A;  2KB4 A;  2CSW A;  2EH0 A;  1QU5 A; 
#chains in the Genus database with same CATH topology
 3PO8 A;  3AFO A;  5C4V A;  1K2M A;  1G3G A;  1DMZ A;  1GXC A;  2I2F A;  3GQS A;  3GMJ A;  1KHX A;  4HAO A;  2LC1 A;  1Y3I A;  3ELV A;  3KT9 A;  3VZB A;  2I2C A;  4DY6 A;  3T5P A;  4WER A;  5BVI A;  2BRF A;  2JQI A;  4JIV D;  5DHP A;  3V8R A;  2JKD A;  1U7F B;  5DHS A;  1J2F A;  1UJX A;  3UNM A;  2BON A;  3V8Q A;  5JEM A;  1LGP A;  3HUF A;  2KB3 A;  2QVL A;  3UV0 A;  3HX1 A;  2QV7 A;  3I0M A;  3UN0 A;  5EJH A;  1U7V B;  1YJM A;  3VA1 A;  1FHR A;  1Z0S A;  2AFF A;  4QCJ A;  2I2D A;  5A8I A;  1DEV A;  3UOT A;  1U0T A;  2JPE A;  5DHQ A;  3VZC A;  2P1R A;  4V24 A;  1MJS A;  5JEL A;  1R21 A;  1MR1 A;  4JIW D;  4WRR A;  3ELS A;  2KKL A;  2I1W A;  2I2A A;  2AN1 A;  1J4O A;  1K3N A;  3POA A;  1YGS A;  2XT9 B;  1J4Q A;  5JEO A;  3UNN A;  3OUN A;  5JEJ A;  2I29 A;  1WLN A;  3DSH A;  4H87 A;  3V7W A;  1LGQ A;  5DHU A;  1G6G A;  5DHR A;  4KU0 D;  4L02 A;  2G1L A;  2W3O A;  2JQJ A;  2JQL A;  1UHT A;  1G88 A;  3I6U A;  3V7U A;  2FF4 A;  3I6W A;  2FEZ A;  5EJI A;  1U7V A;  2A0T A;  2JGR A;  4A0E A;  4EGX A;  5E50 A;  2PIE A;  3VZD A;  3HUE A;  5DJO A;  1KHU A;  3UMZ A;  1MZK A;  4JON A;  5EJG A;  5EJF A;  3V8N A;  2I2B A;  5DHT A;  3DIT A;  1J4P A;  1YT5 A;  1ZOQ A;  3V8P A;  4A4Y A;  3FM8 A;  1MK2 A;  4R9P A;  1J4K A;  1YJ5 C;  3PFN A;  1SUW A;  3A77 A;  1U7F A;  1Y3H A;  1Z0Z A;  3S40 A;  4G2S A;  4EJQ A;  1FHQ A;  1K3J A;  2XXS A;  2Q5F A;  5JER A;  1K3Q A;  2KFU A;  3V7Y A;  3I0N A;  1K2N A;  1Z0U A;  3VA4 A;  5JEK A;  3VPY A;  1QWT A;  4D9V A;  1U0R A;  1DD1 A;  1J4L A;  1WV3 A;  3V8M A;  3MDB A;  3V80 A;  2KB4 A;  2CSW A;  2EH0 A;  1QU5 A; 
#chains in the Genus database with same CATH homology
 3PO8 A;  5C4V A;  1K2M A;  1G3G A;  1DMZ A;  1GXC A;  3GQS A;  3GMJ A;  1KHX A;  2LC1 A;  3ELV A;  3KT9 A;  3VZB A;  3T5P A;  4WER A;  5BVI A;  2BRF A;  2JQI A;  4JIV D;  2JKD A;  1U7F B;  1J2F A;  1UJX A;  3UNM A;  2BON A;  5JEM A;  3HUF A;  1LGP A;  2KB3 A;  2QVL A;  3UV0 A;  3HX1 A;  2QV7 A;  3I0M A;  3UN0 A;  3VA1 A;  1U7V B;  1YJM A;  1FHR A;  2AFF A;  4QCJ A;  5A8I A;  1DEV A;  3UOT A;  2JPE A;  3VZC A;  2P1R A;  4V24 A;  1MJS A;  5JEL A;  1R21 A;  1MR1 A;  4JIW D;  4WRR A;  3ELS A;  2KKL A;  1K3N A;  1J4O A;  3POA A;  1YGS A;  2XT9 B;  1J4Q A;  5JEO A;  3UNN A;  3OUN A;  5JEJ A;  3DSH A;  1WLN A;  4H87 A;  1LGQ A;  1G6G A;  4KU0 D;  4L02 A;  2G1L A;  2W3O A;  2JQJ A;  2JQL A;  1UHT A;  1G88 A;  3I6U A;  2FF4 A;  3I6W A;  2FEZ A;  1U7V A;  2A0T A;  2JGR A;  4A0E A;  4EGX A;  5E50 A;  2PIE A;  3VZD A;  3HUE A;  5DJO A;  1KHU A;  3UMZ A;  1MZK A;  4JON A;  3DIT A;  1J4P A;  1ZOQ A;  4A4Y A;  3FM8 A;  1MK2 A;  4R9P A;  1J4K A;  1YJ5 C;  3A77 A;  1U7F A;  3S40 A;  4G2S A;  4EJQ A;  1FHQ A;  1K3J A;  2XXS A;  5JER A;  1K3Q A;  2KFU A;  3I0N A;  1K2N A;  3VA4 A;  5JEK A;  3VPY A;  1QWT A;  4D9V A;  1DD1 A;  1J4L A;  1WV3 A;  3MDB A;  2KB4 A;  2CSW A;  2EH0 A;  1QU5 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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