2HGF | Genus

Total Genus 14

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus	14
sequence length	97
structure length	97
Chain Sequence	GQRKRRNTIHEFKKSAKTTLIKIDPALKIKTKKVNTADQCANRCTRNKGLPFTCKAFVFDKARKQCLWFPFNSMSSGVKKEFGHEFDLYENKDYIRN

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

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The Resolver thinks Pdb

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reading 97 atoms

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97 atoms created

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After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Genus data interpretation

Chord Diagram

molecule tags	Hepatocyte growth factor
source organism	Homo sapiens
publication title	The solution structure of the N-terminal domain of hepatocyte growth factor reveals a potential heparin-binding site. pubmed doi rcsb
molecule keywords	HEPATOCYTE GROWTH FACTOR
total genus	14
structure length	97
sequence length	97
ec nomenclature
pdb deposition date	1997-12-18

pfam database annotations

chain	Pfam Accession Code	Pfam Family Identifier	Pfam Description
A	PF00024	PAN_1	PAN domain

Image from the rcsb pdb (www.rcsb.org)

cath code	Class	Architecture	Topology	Homology	Domain
3.50.4.10	Alpha Beta	3-Layer(bba) Sandwich	Hepatocyte Growth Factor	Hepatocyte Growth Factor	2hgfA00

2QJ2A 1GMOA 5CT2A 4Z0FA 3ZWZA 2J8LA 4A5TS 1GMNA 5EOKA 5CT1A 4R1AA 2YIOA 3HMSA 2Z8VA 4Z0EA 3HN4A 5CSQA 5CS1A 1I8NA 2K13X 4UV6A 5I25A 3MKPA 1W8KA 2LL3A 3SRJA 1YXEA 2J8JA 5CS9A 4R1CA 5CS3A 4Z09A 3SP8A 1W81A 4APMA 2Y8RA 3HMTA 4UAOA 1NK1A 5CT3A 2X2ZA 2F83A 3HMRA 4APLA 1GP9A 4Z0DA 4DURA 1HKYA 4R19A 2YILA 2Z8WA 5COEA 4IUAA 2LL4M 2QJ4A 2Q8BA 4R1BA 3ZLEA 2YIPA 1Z40A 2Q8AA 5EODA 3SRIA 5CP9A 2HGFA 1BHTA 5CS5A
chains in the Genus database with same CATH superfamily

2QJ2A 1GMOA 5CT2A 4Z0FA 3ZWZA 2J8LA 4YIZA 1GMNA 5EOKA 4A5TS 5CT1A 4R1AA 2YIOA 3HMSA 2Z8VA 4Z0EA 3HN4A 5CSQA 5CS1A 1I8NA 2K13X 4UV6A 5I25A 3MKPA 1W8KA 2LL3A 3SRJA 1YXEA 2J8JA 5CS9A 4R1CA 5CS3A 4Z09A 3SP8A 1W81A 4APMA 2Y8RA 3HMTA 4UAOA 1NK1A 5CT3A 2X2ZA 2F83A 2KL5A 3HMRA 1GP9A 4APLA 4Z0DA 4DURA 1HKYA 4R19A 2YILA 2Z8WA 5COEA 4IUAA 2LL4M 2QJ4A 2Q8BA 4R1BA 3ZLEA 2YIPA 1Z40A 2Q8AA 5EODA 3SRIA 4YIVA 5CP9A 2HGFA 1BHTA 5CS5A
chains in the Genus database with same CATH topology

#chains in the Genus database with same CATH superfamily
 2QJ2 A;  1GMO A;  5CT2 A;  4Z0F A;  3ZWZ A;  2J8L A;  4A5T S;  1GMN A;  5EOK A;  5CT1 A;  4R1A A;  2YIO A;  3HMS A;  2Z8V A;  4Z0E A;  3HN4 A;  5CSQ A;  5CS1 A;  1I8N A;  2K13 X;  4UV6 A;  5I25 A;  3MKP A;  1W8K A;  2LL3 A;  3SRJ A;  1YXE A;  2J8J A;  5CS9 A;  4R1C A;  5CS3 A;  4Z09 A;  3SP8 A;  1W81 A;  4APM A;  2Y8R A;  3HMT A;  4UAO A;  1NK1 A;  5CT3 A;  2X2Z A;  2F83 A;  3HMR A;  4APL A;  1GP9 A;  4Z0D A;  4DUR A;  1HKY A;  4R19 A;  2YIL A;  2Z8W A;  5COE A;  4IUA A;  2LL4 M;  2QJ4 A;  2Q8B A;  4R1B A;  3ZLE A;  2YIP A;  1Z40 A;  2Q8A A;  5EOD A;  3SRI A;  5CP9 A;  2HGF A;  1BHT A;  5CS5 A; 
#chains in the Genus database with same CATH topology
 2QJ2 A;  1GMO A;  5CT2 A;  4Z0F A;  3ZWZ A;  2J8L A;  4YIZ A;  1GMN A;  5EOK A;  4A5T S;  5CT1 A;  4R1A A;  2YIO A;  3HMS A;  2Z8V A;  4Z0E A;  3HN4 A;  5CSQ A;  5CS1 A;  1I8N A;  2K13 X;  4UV6 A;  5I25 A;  3MKP A;  1W8K A;  2LL3 A;  3SRJ A;  1YXE A;  2J8J A;  5CS9 A;  4R1C A;  5CS3 A;  4Z09 A;  3SP8 A;  1W81 A;  4APM A;  2Y8R A;  3HMT A;  4UAO A;  1NK1 A;  5CT3 A;  2X2Z A;  2F83 A;  2KL5 A;  3HMR A;  1GP9 A;  4APL A;  4Z0D A;  4DUR A;  1HKY A;  4R19 A;  2YIL A;  2Z8W A;  5COE A;  4IUA A;  2LL4 M;  2QJ4 A;  2Q8B A;  4R1B A;  3ZLE A;  2YIP A;  1Z40 A;  2Q8A A;  5EOD A;  3SRI A;  4YIV A;  5CP9 A;  2HGF A;  1BHT A;  5CS5 A; 
#chains in the Genus database with same CATH homology
 2QJ2 A;  1GMO A;  5CT2 A;  4Z0F A;  3ZWZ A;  2J8L A;  4YIZ A;  1GMN A;  5EOK A;  4A5T S;  5CT1 A;  4R1A A;  2YIO A;  3HMS A;  2Z8V A;  4Z0E A;  3HN4 A;  5CSQ A;  5CS1 A;  1I8N A;  2K13 X;  4UV6 A;  5I25 A;  3MKP A;  1W8K A;  2LL3 A;  3SRJ A;  1YXE A;  2J8J A;  5CS9 A;  4R1C A;  5CS3 A;  4Z09 A;  3SP8 A;  1W81 A;  4APM A;  2Y8R A;  3HMT A;  4UAO A;  1NK1 A;  5CT3 A;  2X2Z A;  2F83 A;  2KL5 A;  3HMR A;  1GP9 A;  4APL A;  4Z0D A;  4DUR A;  1HKY A;  4R19 A;  2YIL A;  2Z8W A;  5COE A;  4IUA A;  2LL4 M;  2QJ4 A;  2Q8B A;  4R1B A;  3ZLE A;  2YIP A;  1Z40 A;  2Q8A A;  5EOD A;  3SRI A;  4YIV A;  5CP9 A;  2HGF A;  1BHT A;  5CS5 A;

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similar chains in the Genus database (?% sequence similarity)

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similar chains in the pdb database (?% sequence similarity)

#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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2HGFA

Total Genus

sequence length

structure length

Chain Sequence

Structure visualization

Chord Diagram

connected with : NaN

pfam database annotations