2K13X

Solution nmr structure of the leech protein saratin, a novel inhibitor of haemostasis
Total Genus 21
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
21
sequence length
103
structure length
103
Chain Sequence
EEREDCWTFYANRKYTDFDKSFKKSSDLDECKKTCFKTEYCYIVFEDTVNKECYYNVVDGEELDQEKFVVDENFTENYLTDCEGKDAGNAAGTGDESDEVDED
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structure of the leech protein saratin and characterization of its binding to collagen
pubmed doi rcsb
molecule tags Toxin
molecule keywords Saratin
total genus 21
structure length 103
sequence length 103
ec nomenclature
pdb deposition date 2008-02-20
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.50.4.10 Alpha Beta 3-Layer(bba) Sandwich Hepatocyte Growth Factor Hepatocyte Growth Factor 2k13X00
5EODA 5CS5A 4R1CA 3MKPA 3HN4A 3ZLEA 5CT2A 4Z0FA 5CT3A 1YXEA 3SRJA 4UV6A 5EOKA 4UAOA 1GMOA 3SRIA 4Z0EA 2YILA 2Q8AA 2YIPA 2Z8WA 5CT1A 2QJ2A 3ZWZA 4IUAA 2LL3A 4R19A 2Y8RA 1W8KA 1Z40A 5CS1A 5CS9A 4APMA 4R1AA 2J8JA 2K13X 5CS3A 1HKYA 4R1BA 2YIOA 1GP9A 4Z09A 1I8NA 2HGFA 3HMSA 4A5TS 5CSQA 4APLA 1W81A 4Z0DA 5I25A 1GMNA 5CP9A 2F83A 1NK1A 2QJ4A 1BHTA 2Q8BA 3HMRA 2Z8VA 5COEA 2LL4M 3SP8A 2J8LA 4DURA 2X2ZA 3HMTA
chains in the Genus database with same CATH superfamily
5EODA 5CS5A 4R1CA 3MKPA 3HN4A 3ZLEA 5CT2A 4Z0FA 5CT3A 1YXEA 4YIZA 4UV6A 5EOKA 4UAOA 1GMOA 3SRJA 3SRIA 4Z0EA 2YILA 4YIVA 2Q8AA 2YIPA 2Z8WA 5CT1A 2QJ2A 3ZWZA 4IUAA 2LL3A 4R19A 2Y8RA 1W8KA 1Z40A 5CS1A 5CS9A 4APMA 4R1AA 2J8JA 2K13X 5CS3A 1HKYA 4R1BA 2YIOA 1GP9A 4Z09A 1I8NA 2HGFA 3HMSA 4A5TS 5CSQA 4APLA 1W81A 4Z0DA 5I25A 1GMNA 5CP9A 2F83A 1NK1A 2QJ4A 2KL5A 1BHTA 2Q8BA 3HMRA 2Z8VA 5COEA 2LL4M 3SP8A 2J8LA 4DURA 2X2ZA 3HMTA
chains in the Genus database with same CATH topology
5EODA 5CS5A 4R1CA 3MKPA 3HN4A 3ZLEA 5CT2A 4Z0FA 5CT3A 1YXEA 4YIZA 4UV6A 5EOKA 4UAOA 1GMOA 3SRJA 3SRIA 4Z0EA 2YILA 4YIVA 2Q8AA 2YIPA 2Z8WA 5CT1A 2QJ2A 3ZWZA 4IUAA 2LL3A 4R19A 2Y8RA 1W8KA 1Z40A 5CS1A 5CS9A 4APMA 4R1AA 2J8JA 2K13X 5CS3A 1HKYA 4R1BA 2YIOA 1GP9A 4Z09A 1I8NA 2HGFA 3HMSA 4A5TS 5CSQA 4APLA 1W81A 4Z0DA 5I25A 1GMNA 5CP9A 2F83A 1NK1A 2QJ4A 2KL5A 1BHTA 2Q8BA 3HMRA 2Z8VA 5COEA 2LL4M 3SP8A 2J8LA 4DURA 2X2ZA 3HMTA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 5EOD A;  5CS5 A;  4R1C A;  3MKP A;  3HN4 A;  3ZLE A;  5CT2 A;  4Z0F A;  5CT3 A;  1YXE A;  3SRJ A;  4UV6 A;  5EOK A;  4UAO A;  1GMO A;  3SRI A;  4Z0E A;  2YIL A;  2Q8A A;  2YIP A;  2Z8W A;  5CT1 A;  2QJ2 A;  3ZWZ A;  4IUA A;  2LL3 A;  4R19 A;  2Y8R A;  1W8K A;  1Z40 A;  5CS1 A;  5CS9 A;  4APM A;  4R1A A;  2J8J A;  2K13 X;  5CS3 A;  1HKY A;  4R1B A;  2YIO A;  1GP9 A;  4Z09 A;  1I8N A;  2HGF A;  3HMS A;  4A5T S;  5CSQ A;  4APL A;  1W81 A;  4Z0D A;  5I25 A;  1GMN A;  5CP9 A;  2F83 A;  1NK1 A;  2QJ4 A;  1BHT A;  2Q8B A;  3HMR A;  2Z8V A;  5COE A;  2LL4 M;  3SP8 A;  2J8L A;  4DUR A;  2X2Z A;  3HMT A; 
#chains in the Genus database with same CATH topology
 5EOD A;  5CS5 A;  4R1C A;  3MKP A;  3HN4 A;  3ZLE A;  5CT2 A;  4Z0F A;  5CT3 A;  1YXE A;  4YIZ A;  4UV6 A;  5EOK A;  4UAO A;  1GMO A;  3SRJ A;  3SRI A;  4Z0E A;  2YIL A;  4YIV A;  2Q8A A;  2YIP A;  2Z8W A;  5CT1 A;  2QJ2 A;  3ZWZ A;  4IUA A;  2LL3 A;  4R19 A;  2Y8R A;  1W8K A;  1Z40 A;  5CS1 A;  5CS9 A;  4APM A;  4R1A A;  2J8J A;  2K13 X;  5CS3 A;  1HKY A;  4R1B A;  2YIO A;  1GP9 A;  4Z09 A;  1I8N A;  2HGF A;  3HMS A;  4A5T S;  5CSQ A;  4APL A;  1W81 A;  4Z0D A;  5I25 A;  1GMN A;  5CP9 A;  2F83 A;  1NK1 A;  2QJ4 A;  2KL5 A;  1BHT A;  2Q8B A;  3HMR A;  2Z8V A;  5COE A;  2LL4 M;  3SP8 A;  2J8L A;  4DUR A;  2X2Z A;  3HMT A; 
#chains in the Genus database with same CATH homology
 5EOD A;  5CS5 A;  4R1C A;  3MKP A;  3HN4 A;  3ZLE A;  5CT2 A;  4Z0F A;  5CT3 A;  1YXE A;  4YIZ A;  4UV6 A;  5EOK A;  4UAO A;  1GMO A;  3SRJ A;  3SRI A;  4Z0E A;  2YIL A;  4YIV A;  2Q8A A;  2YIP A;  2Z8W A;  5CT1 A;  2QJ2 A;  3ZWZ A;  4IUA A;  2LL3 A;  4R19 A;  2Y8R A;  1W8K A;  1Z40 A;  5CS1 A;  5CS9 A;  4APM A;  4R1A A;  2J8J A;  2K13 X;  5CS3 A;  1HKY A;  4R1B A;  2YIO A;  1GP9 A;  4Z09 A;  1I8N A;  2HGF A;  3HMS A;  4A5T S;  5CSQ A;  4APL A;  1W81 A;  4Z0D A;  5I25 A;  1GMN A;  5CP9 A;  2F83 A;  1NK1 A;  2QJ4 A;  2KL5 A;  1BHT A;  2Q8B A;  3HMR A;  2Z8V A;  5COE A;  2LL4 M;  3SP8 A;  2J8L A;  4DUR A;  2X2Z A;  3HMT A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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