2K13X

Solution nmr structure of the leech protein saratin, a novel inhibitor of haemostasis
Total Genus 21
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
21
sequence length
103
structure length
103
Chain Sequence
EEREDCWTFYANRKYTDFDKSFKKSSDLDECKKTCFKTEYCYIVFEDTVNKECYYNVVDGEELDQEKFVVDENFTENYLTDCEGKDAGNAAGTGDESDEVDED
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Toxin
molecule keywords Saratin
publication title Structure of the leech protein saratin and characterization of its binding to collagen
pubmed doi rcsb
total genus 21
structure length 103
sequence length 103
ec nomenclature
pdb deposition date 2008-02-20
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.50.4.10 Alpha Beta 3-Layer(bba) Sandwich Hepatocyte Growth Factor Hepatocyte Growth Factor 2k13X00
5CT1A 5EODA 4DURA 2YILA 3HMRA 4R1CA 1HKYA 1W81A 3HMSA 2Z8WA 5CT2A 2J8JA 3SP8A 3SRJA 4APLA 2X2ZA 2YIPA 5CSQA 4Z09A 2LL3A 4APMA 4IUAA 4UAOA 1W8KA 4Z0EA 2QJ2A 5I25A 4R1BA 1I8NA 4R1AA 1GMNA 2Q8AA 3HMTA 5EOKA 5CS5A 2Q8BA 2QJ4A 4Z0FA 2Z8VA 3SRIA 3ZLEA 2LL4M 2J8LA 1GP9A 1NK1A 2K13X 2YIOA 5COEA 3HN4A 2Y8RA 5CS1A 5CT3A 1BHTA 1Z40A 3ZWZA 5CP9A 5CS3A 4R19A 3MKPA 1YXEA 5CS9A 4Z0DA 2HGFA 1GMOA 4A5TS 2F83A 4UV6A
chains in the Genus database with same CATH superfamily
5CT1A 5EODA 4DURA 2YILA 3HMRA 4R1CA 1HKYA 1W81A 3HMSA 2Z8WA 5CT2A 2J8JA 4YIVA 3SP8A 3SRJA 2X2ZA 2YIPA 5CSQA 4Z09A 2LL3A 4APLA 4APMA 4IUAA 4UAOA 1W8KA 4Z0EA 2QJ2A 5I25A 4R1BA 1I8NA 4R1AA 1GMNA 2Q8AA 3HMTA 5EOKA 5CS5A 2Q8BA 2QJ4A 4Z0FA 2Z8VA 3SRIA 3ZLEA 2LL4M 2J8LA 1GP9A 1NK1A 2K13X 2YIOA 4YIZA 3HN4A 2Y8RA 5COEA 5CS1A 5CT3A 1BHTA 1Z40A 3ZWZA 5CP9A 5CS3A 4R19A 3MKPA 1YXEA 5CS9A 2KL5A 4Z0DA 2HGFA 1GMOA 4A5TS 2F83A 4UV6A
chains in the Genus database with same CATH topology
5CT1A 5EODA 4DURA 2YILA 3HMRA 4R1CA 1HKYA 1W81A 3HMSA 2Z8WA 5CT2A 2J8JA 4YIVA 3SP8A 3SRJA 2X2ZA 2YIPA 5CSQA 4Z09A 2LL3A 4APLA 4APMA 4IUAA 4UAOA 1W8KA 4Z0EA 2QJ2A 5I25A 4R1BA 1I8NA 4R1AA 1GMNA 2Q8AA 3HMTA 5EOKA 5CS5A 2Q8BA 2QJ4A 4Z0FA 2Z8VA 3SRIA 3ZLEA 2LL4M 2J8LA 1GP9A 1NK1A 2K13X 2YIOA 4YIZA 3HN4A 2Y8RA 5COEA 5CS1A 5CT3A 1BHTA 1Z40A 3ZWZA 5CP9A 5CS3A 4R19A 3MKPA 1YXEA 5CS9A 2KL5A 4Z0DA 2HGFA 1GMOA 4A5TS 2F83A 4UV6A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 5CT1 A;  5EOD A;  4DUR A;  2YIL A;  3HMR A;  4R1C A;  1HKY A;  1W81 A;  3HMS A;  2Z8W A;  5CT2 A;  2J8J A;  3SP8 A;  3SRJ A;  4APL A;  2X2Z A;  2YIP A;  5CSQ A;  4Z09 A;  2LL3 A;  4APM A;  4IUA A;  4UAO A;  1W8K A;  4Z0E A;  2QJ2 A;  5I25 A;  4R1B A;  1I8N A;  4R1A A;  1GMN A;  2Q8A A;  3HMT A;  5EOK A;  5CS5 A;  2Q8B A;  2QJ4 A;  4Z0F A;  2Z8V A;  3SRI A;  3ZLE A;  2LL4 M;  2J8L A;  1GP9 A;  1NK1 A;  2K13 X;  2YIO A;  5COE A;  3HN4 A;  2Y8R A;  5CS1 A;  5CT3 A;  1BHT A;  1Z40 A;  3ZWZ A;  5CP9 A;  5CS3 A;  4R19 A;  3MKP A;  1YXE A;  5CS9 A;  4Z0D A;  2HGF A;  1GMO A;  4A5T S;  2F83 A;  4UV6 A; 
#chains in the Genus database with same CATH topology
 5CT1 A;  5EOD A;  4DUR A;  2YIL A;  3HMR A;  4R1C A;  1HKY A;  1W81 A;  3HMS A;  2Z8W A;  5CT2 A;  2J8J A;  4YIV A;  3SP8 A;  3SRJ A;  2X2Z A;  2YIP A;  5CSQ A;  4Z09 A;  2LL3 A;  4APL A;  4APM A;  4IUA A;  4UAO A;  1W8K A;  4Z0E A;  2QJ2 A;  5I25 A;  4R1B A;  1I8N A;  4R1A A;  1GMN A;  2Q8A A;  3HMT A;  5EOK A;  5CS5 A;  2Q8B A;  2QJ4 A;  4Z0F A;  2Z8V A;  3SRI A;  3ZLE A;  2LL4 M;  2J8L A;  1GP9 A;  1NK1 A;  2K13 X;  2YIO A;  4YIZ A;  3HN4 A;  2Y8R A;  5COE A;  5CS1 A;  5CT3 A;  1BHT A;  1Z40 A;  3ZWZ A;  5CP9 A;  5CS3 A;  4R19 A;  3MKP A;  1YXE A;  5CS9 A;  2KL5 A;  4Z0D A;  2HGF A;  1GMO A;  4A5T S;  2F83 A;  4UV6 A; 
#chains in the Genus database with same CATH homology
 5CT1 A;  5EOD A;  4DUR A;  2YIL A;  3HMR A;  4R1C A;  1HKY A;  1W81 A;  3HMS A;  2Z8W A;  5CT2 A;  2J8J A;  4YIV A;  3SP8 A;  3SRJ A;  2X2Z A;  2YIP A;  5CSQ A;  4Z09 A;  2LL3 A;  4APL A;  4APM A;  4IUA A;  4UAO A;  1W8K A;  4Z0E A;  2QJ2 A;  5I25 A;  4R1B A;  1I8N A;  4R1A A;  1GMN A;  2Q8A A;  3HMT A;  5EOK A;  5CS5 A;  2Q8B A;  2QJ4 A;  4Z0F A;  2Z8V A;  3SRI A;  3ZLE A;  2LL4 M;  2J8L A;  1GP9 A;  1NK1 A;  2K13 X;  2YIO A;  4YIZ A;  3HN4 A;  2Y8R A;  5COE A;  5CS1 A;  5CT3 A;  1BHT A;  1Z40 A;  3ZWZ A;  5CP9 A;  5CS3 A;  4R19 A;  3MKP A;  1YXE A;  5CS9 A;  2KL5 A;  4Z0D A;  2HGF A;  1GMO A;  4A5T S;  2F83 A;  4UV6 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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