4Z0FA

Crystal structure of fvo strain plasmodium falciparum ama1 in complex with the ron2hp [phe2038(6cw)] peptide
Total Genus 75
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
75
sequence length
332
structure length
278
Chain Sequence
GNPWTEYMAKYDIEEVHGSGIRVDLGEDAEVAGTQYRLPSGKCPVFGKGIIIENSNTTFLKPVATLKDGGFAFPPTNPLISPMTLNGMRDFYKNNEYVKNLDELTLCSRHAGNMNPDNKNSNYKYPAVYDYNDKKCHILYIAAQENNFCFRPAKDKLFENYTYLSKNVVDNWEEVCPRKNLENAKFGLWVDGNCEDIPHVNEFSANDLFECNKLVFELSASDQPKQYDRYKSHGKGYNWGNYNRETQKCEIFNVKPTCLINNSSYIATTALSHPIEVE
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Cell invasion
molecule keywords Apical membrane antigen 1
publication title Structure-Activity Studies of beta-Hairpin Peptide Inhibitors of the Plasmodium falciparum AMA1-RON2 Interaction.
pubmed doi rcsb
source organism Plasmodium falciparum vietnam oak-knoll (fvo)
total genus 75
structure length 278
sequence length 332
ec nomenclature
pdb deposition date 2015-03-26
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.50.4.10 Alpha Beta 3-Layer(bba) Sandwich Hepatocyte Growth Factor Hepatocyte Growth Factor 4z0fA01
3MKPA 5EOKA 5CS1A 4Z09A 5CT3A 5CSQA 4DURA 5CT1A 4UV6A 1GP9A 1BHTA 3SP8A 3ZWZA 3ZLEA 2LL4M 4IUAA 5I25A 3SRIA 2QJ4A 2J8LA 2Z8VA 3HMRA 2Q8BA 4APMA 3SRJA 4A5TS 4R19A 2K13X 2Y8RA 2YIOA 1W81A 1GMOA 4R1AA 2J8JA 1HKYA 2Z8WA 4R1BA 4APLA 2QJ2A 2X2ZA 1YXEA 1W8KA 4R1CA 1GMNA 5CS9A 5COEA 5CP9A 1NK1A 3HN4A 4Z0DA 1I8NA 2YIPA 5CT2A 2LL3A 2Q8AA 4Z0FA 4Z0EA 2F83A 1Z40A 2YILA 5EODA 5CS3A 5CS5A 2HGFA 3HMSA 3HMTA 4UAOA
chains in the Genus database with same CATH superfamily
3MKPA 5EOKA 5CS1A 4Z09A 5CT3A 5CSQA 4DURA 5CT1A 4UV6A 4YIZA 1GP9A 1BHTA 3SP8A 3ZWZA 3ZLEA 2LL4M 4IUAA 5I25A 3SRIA 2QJ4A 2J8LA 2Z8VA 3HMRA 2Q8BA 4APMA 3SRJA 4A5TS 4R19A 2K13X 2Y8RA 2YIOA 1W81A 1GMOA 4R1AA 2J8JA 1HKYA 2Z8WA 4R1BA 2KL5A 4APLA 2QJ2A 2X2ZA 1YXEA 1W8KA 4R1CA 1GMNA 5CS9A 5COEA 5CP9A 1NK1A 3HN4A 4Z0DA 1I8NA 2YIPA 5CT2A 2LL3A 2Q8AA 4Z0FA 4Z0EA 2F83A 1Z40A 2YILA 5EODA 4YIVA 5CS3A 5CS5A 2HGFA 3HMSA 3HMTA 4UAOA
chains in the Genus database with same CATH topology
3MKPA 5EOKA 5CS1A 4Z09A 5CT3A 5CSQA 4DURA 5CT1A 4UV6A 4YIZA 1GP9A 1BHTA 3SP8A 3ZWZA 3ZLEA 2LL4M 4IUAA 5I25A 3SRIA 2QJ4A 2J8LA 2Z8VA 3HMRA 2Q8BA 4APMA 3SRJA 4A5TS 4R19A 2K13X 2Y8RA 2YIOA 1W81A 1GMOA 4R1AA 2J8JA 1HKYA 2Z8WA 4R1BA 2KL5A 4APLA 2QJ2A 2X2ZA 1YXEA 1W8KA 4R1CA 1GMNA 5CS9A 5COEA 5CP9A 1NK1A 3HN4A 4Z0DA 1I8NA 2YIPA 5CT2A 2LL3A 2Q8AA 4Z0FA 4Z0EA 2F83A 1Z40A 2YILA 5EODA 4YIVA 5CS3A 5CS5A 2HGFA 3HMSA 3HMTA 4UAOA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3MKP A;  5EOK A;  5CS1 A;  4Z09 A;  5CT3 A;  5CSQ A;  4DUR A;  5CT1 A;  4UV6 A;  1GP9 A;  1BHT A;  3SP8 A;  3ZWZ A;  3ZLE A;  2LL4 M;  4IUA A;  5I25 A;  3SRI A;  2QJ4 A;  2J8L A;  2Z8V A;  3HMR A;  2Q8B A;  4APM A;  3SRJ A;  4A5T S;  4R19 A;  2K13 X;  2Y8R A;  2YIO A;  1W81 A;  1GMO A;  4R1A A;  2J8J A;  1HKY A;  2Z8W A;  4R1B A;  4APL A;  2QJ2 A;  2X2Z A;  1YXE A;  1W8K A;  4R1C A;  1GMN A;  5CS9 A;  5COE A;  5CP9 A;  1NK1 A;  3HN4 A;  4Z0D A;  1I8N A;  2YIP A;  5CT2 A;  2LL3 A;  2Q8A A;  4Z0F A;  4Z0E A;  2F83 A;  1Z40 A;  2YIL A;  5EOD A;  5CS3 A;  5CS5 A;  2HGF A;  3HMS A;  3HMT A;  4UAO A; 
#chains in the Genus database with same CATH topology
 3MKP A;  5EOK A;  5CS1 A;  4Z09 A;  5CT3 A;  5CSQ A;  4DUR A;  5CT1 A;  4UV6 A;  4YIZ A;  1GP9 A;  1BHT A;  3SP8 A;  3ZWZ A;  3ZLE A;  2LL4 M;  4IUA A;  5I25 A;  3SRI A;  2QJ4 A;  2J8L A;  2Z8V A;  3HMR A;  2Q8B A;  4APM A;  3SRJ A;  4A5T S;  4R19 A;  2K13 X;  2Y8R A;  2YIO A;  1W81 A;  1GMO A;  4R1A A;  2J8J A;  1HKY A;  2Z8W A;  4R1B A;  2KL5 A;  4APL A;  2QJ2 A;  2X2Z A;  1YXE A;  1W8K A;  4R1C A;  1GMN A;  5CS9 A;  5COE A;  5CP9 A;  1NK1 A;  3HN4 A;  4Z0D A;  1I8N A;  2YIP A;  5CT2 A;  2LL3 A;  2Q8A A;  4Z0F A;  4Z0E A;  2F83 A;  1Z40 A;  2YIL A;  5EOD A;  4YIV A;  5CS3 A;  5CS5 A;  2HGF A;  3HMS A;  3HMT A;  4UAO A; 
#chains in the Genus database with same CATH homology
 3MKP A;  5EOK A;  5CS1 A;  4Z09 A;  5CT3 A;  5CSQ A;  4DUR A;  5CT1 A;  4UV6 A;  4YIZ A;  1GP9 A;  1BHT A;  3SP8 A;  3ZWZ A;  3ZLE A;  2LL4 M;  4IUA A;  5I25 A;  3SRI A;  2QJ4 A;  2J8L A;  2Z8V A;  3HMR A;  2Q8B A;  4APM A;  3SRJ A;  4A5T S;  4R19 A;  2K13 X;  2Y8R A;  2YIO A;  1W81 A;  1GMO A;  4R1A A;  2J8J A;  1HKY A;  2Z8W A;  4R1B A;  2KL5 A;  4APL A;  2QJ2 A;  2X2Z A;  1YXE A;  1W8K A;  4R1C A;  1GMN A;  5CS9 A;  5COE A;  5CP9 A;  1NK1 A;  3HN4 A;  4Z0D A;  1I8N A;  2YIP A;  5CT2 A;  2LL3 A;  2Q8A A;  4Z0F A;  4Z0E A;  2F83 A;  1Z40 A;  2YIL A;  5EOD A;  4YIV A;  5CS3 A;  5CS5 A;  2HGF A;  3HMS A;  3HMT A;  4UAO A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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