4Z0EA

Crystal structure of fvo strain plasmodium falciparum ama1 in complex with the ron2hp [phe2038trn] peptide
Total Genus 77
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
77
sequence length
331
structure length
270
Chain Sequence
b'NPWTEYMAKYDIEEVHGSGIRVDLGEDAEVGTQYRLPSGKCPVFGKGIIIETTFLKPVAKDGGFAFPPTNPLISPMTLNGMRDFYKNNEYVKNLDELTLCSRHAGNMNPDNKNSNYKYPAVYDYNDKKCHILYIAAQENNGFCFRPAKDKLFENYTYLSKNVVDNWEEVCPRKNLENAKFGLWVDGNCEDIPHVNEFSANDLFECNKLVFELSASDQPKDRYKSHGKGYNWGNYNRETQKCEIFNVKPTCLINNSSYIATTALSHPIEVE'
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule keywords Apical membrane antigen 1
publication title Structure-Activity Studies of beta-Hairpin Peptide Inhibitors of the Plasmodium falciparum AMA1-RON2 Interaction.
pubmed doi rcsb
source organism Plasmodium falciparum vietnam oak-knoll (fvo)
molecule tags Cell invasion
total genus 77
structure length 270
sequence length 331
ec nomenclature
pdb deposition date 2015-03-26
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.50.4.10 Alpha Beta 3-Layer(bba) Sandwich Hepatocyte Growth Factor Hepatocyte Growth Factor 4z0eA01
2YIOA 2LL4M 3ZWZA 4IUAA 2X2ZA 5CS5A 3HN4A 2Y8RA 1BHTA 4R1BA 3HMRA 2QJ4A 4UV6A 2J8JA 5CS3A 3HMTA 5EOKA 2F83A 1I8NA 2YILA 2LL3A 2K13X 5EODA 1Z40A 1GMNA 1HKYA 2Z8VA 4APLA 4R19A 3SRJA 2Z8WA 4Z0FA 4DURA 2J8LA 5CT3A 3HMSA 2QJ2A 4UAOA 4Z09A 3ZLEA 4APMA 5CT1A 5I25A 2Q8AA 1W8KA 4Z0DA 4A5TS 5CSQA 5CS1A 1NK1A 5CP9A 4Z0EA 3SP8A 3SRIA 1GMOA 1YXEA 2HGFA 5COEA 3MKPA 5CS9A 4R1AA 5CT2A 2YIPA 2Q8BA 4R1CA 1GP9A 1W81A
chains in the Genus database with same CATH superfamily
2YIOA 2LL4M 3ZWZA 4IUAA 2X2ZA 5CS5A 3HN4A 4YIVA 2Y8RA 1BHTA 4R1BA 3HMRA 2QJ4A 4UV6A 2J8JA 5CS3A 3HMTA 5EOKA 2F83A 1I8NA 4YIZA 2YILA 2LL3A 2K13X 5EODA 1Z40A 1GMNA 1HKYA 2KL5A 2Z8VA 4R19A 4APLA 3SRJA 2Z8WA 4Z0FA 4DURA 2J8LA 5CT3A 3HMSA 2QJ2A 4UAOA 4Z09A 3ZLEA 4APMA 5CT1A 5I25A 2Q8AA 1W8KA 4Z0DA 4A5TS 5CSQA 5CS1A 1NK1A 5CP9A 4Z0EA 3SP8A 3SRIA 1GMOA 1YXEA 2HGFA 5COEA 3MKPA 5CS9A 4R1AA 5CT2A 2YIPA 2Q8BA 4R1CA 1GP9A 1W81A
chains in the Genus database with same CATH topology
2YIOA 2LL4M 3ZWZA 4IUAA 2X2ZA 5CS5A 3HN4A 4YIVA 2Y8RA 1BHTA 4R1BA 3HMRA 2QJ4A 4UV6A 2J8JA 5CS3A 3HMTA 5EOKA 2F83A 1I8NA 4YIZA 2YILA 2LL3A 2K13X 5EODA 1Z40A 1GMNA 1HKYA 2KL5A 2Z8VA 4R19A 4APLA 3SRJA 2Z8WA 4Z0FA 4DURA 2J8LA 5CT3A 3HMSA 2QJ2A 4UAOA 4Z09A 3ZLEA 4APMA 5CT1A 5I25A 2Q8AA 1W8KA 4Z0DA 4A5TS 5CSQA 5CS1A 1NK1A 5CP9A 4Z0EA 3SP8A 3SRIA 1GMOA 1YXEA 2HGFA 5COEA 3MKPA 5CS9A 4R1AA 5CT2A 2YIPA 2Q8BA 4R1CA 1GP9A 1W81A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2YIO A;  2LL4 M;  3ZWZ A;  4IUA A;  2X2Z A;  5CS5 A;  3HN4 A;  2Y8R A;  1BHT A;  4R1B A;  3HMR A;  2QJ4 A;  4UV6 A;  2J8J A;  5CS3 A;  3HMT A;  5EOK A;  2F83 A;  1I8N A;  2YIL A;  2LL3 A;  2K13 X;  5EOD A;  1Z40 A;  1GMN A;  1HKY A;  2Z8V A;  4APL A;  4R19 A;  3SRJ A;  2Z8W A;  4Z0F A;  4DUR A;  2J8L A;  5CT3 A;  3HMS A;  2QJ2 A;  4UAO A;  4Z09 A;  3ZLE A;  4APM A;  5CT1 A;  5I25 A;  2Q8A A;  1W8K A;  4Z0D A;  4A5T S;  5CSQ A;  5CS1 A;  1NK1 A;  5CP9 A;  4Z0E A;  3SP8 A;  3SRI A;  1GMO A;  1YXE A;  2HGF A;  5COE A;  3MKP A;  5CS9 A;  4R1A A;  5CT2 A;  2YIP A;  2Q8B A;  4R1C A;  1GP9 A;  1W81 A; 
#chains in the Genus database with same CATH topology
 2YIO A;  2LL4 M;  3ZWZ A;  4IUA A;  2X2Z A;  5CS5 A;  3HN4 A;  4YIV A;  2Y8R A;  1BHT A;  4R1B A;  3HMR A;  2QJ4 A;  4UV6 A;  2J8J A;  5CS3 A;  3HMT A;  5EOK A;  2F83 A;  1I8N A;  4YIZ A;  2YIL A;  2LL3 A;  2K13 X;  5EOD A;  1Z40 A;  1GMN A;  1HKY A;  2KL5 A;  2Z8V A;  4R19 A;  4APL A;  3SRJ A;  2Z8W A;  4Z0F A;  4DUR A;  2J8L A;  5CT3 A;  3HMS A;  2QJ2 A;  4UAO A;  4Z09 A;  3ZLE A;  4APM A;  5CT1 A;  5I25 A;  2Q8A A;  1W8K A;  4Z0D A;  4A5T S;  5CSQ A;  5CS1 A;  1NK1 A;  5CP9 A;  4Z0E A;  3SP8 A;  3SRI A;  1GMO A;  1YXE A;  2HGF A;  5COE A;  3MKP A;  5CS9 A;  4R1A A;  5CT2 A;  2YIP A;  2Q8B A;  4R1C A;  1GP9 A;  1W81 A; 
#chains in the Genus database with same CATH homology
 2YIO A;  2LL4 M;  3ZWZ A;  4IUA A;  2X2Z A;  5CS5 A;  3HN4 A;  4YIV A;  2Y8R A;  1BHT A;  4R1B A;  3HMR A;  2QJ4 A;  4UV6 A;  2J8J A;  5CS3 A;  3HMT A;  5EOK A;  2F83 A;  1I8N A;  4YIZ A;  2YIL A;  2LL3 A;  2K13 X;  5EOD A;  1Z40 A;  1GMN A;  1HKY A;  2KL5 A;  2Z8V A;  4R19 A;  4APL A;  3SRJ A;  2Z8W A;  4Z0F A;  4DUR A;  2J8L A;  5CT3 A;  3HMS A;  2QJ2 A;  4UAO A;  4Z09 A;  3ZLE A;  4APM A;  5CT1 A;  5I25 A;  2Q8A A;  1W8K A;  4Z0D A;  4A5T S;  5CSQ A;  5CS1 A;  1NK1 A;  5CP9 A;  4Z0E A;  3SP8 A;  3SRI A;  1GMO A;  1YXE A;  2HGF A;  5COE A;  3MKP A;  5CS9 A;  4R1A A;  5CT2 A;  2YIP A;  2Q8B A;  4R1C A;  1GP9 A;  1W81 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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