4Z0EA

Crystal structure of fvo strain plasmodium falciparum ama1 in complex with the ron2hp [phe2038trn] peptide
Total Genus 77
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
77
sequence length
331
structure length
270
Chain Sequence
NPWTEYMAKYDIEEVHGSGIRVDLGEDAEVGTQYRLPSGKCPVFGKGIIIETTFLKPVAKDGGFAFPPTNPLISPMTLNGMRDFYKNNEYVKNLDELTLCSRHAGNMNPDNKNSNYKYPAVYDYNDKKCHILYIAAQENNGFCFRPAKDKLFENYTYLSKNVVDNWEEVCPRKNLENAKFGLWVDGNCEDIPHVNEFSANDLFECNKLVFELSASDQPKDRYKSHGKGYNWGNYNRETQKCEIFNVKPTCLINNSSYIATTALSHPIEVE
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Cell invasion
molecule keywords Apical membrane antigen 1
publication title Structure-Activity Studies of beta-Hairpin Peptide Inhibitors of the Plasmodium falciparum AMA1-RON2 Interaction.
pubmed doi rcsb
source organism Plasmodium falciparum vietnam oak-knoll (fvo)
total genus 77
structure length 270
sequence length 331
ec nomenclature
pdb deposition date 2015-03-26
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.50.4.10 Alpha Beta 3-Layer(bba) Sandwich Hepatocyte Growth Factor Hepatocyte Growth Factor 4z0eA01
2HGFA 5CS5A 2K13X 5COEA 4R19A 2Z8VA 4UAOA 2Z8WA 4APMA 1HKYA 2QJ4A 3HMSA 2YIOA 5CT3A 5CSQA 2QJ2A 1W81A 1GP9A 4R1BA 3HMRA 4Z0FA 5CS9A 4Z0DA 3SP8A 4IUAA 4R1AA 2LL3A 3HMTA 1GMNA 5I25A 3ZWZA 1I8NA 4UV6A 2Q8BA 1YXEA 3MKPA 1W8KA 4A5TS 2X2ZA 5EOKA 5CS3A 1NK1A 4Z09A 3SRJA 3HN4A 2F83A 2J8LA 5CT2A 5EODA 2Y8RA 3SRIA 4APLA 5CT1A 5CS1A 3ZLEA 2YIPA 2YILA 1BHTA 2Q8AA 4DURA 4Z0EA 1Z40A 4R1CA 2LL4M 5CP9A 2J8JA 1GMOA
chains in the Genus database with same CATH superfamily
2HGFA 5CS5A 2K13X 5COEA 4R19A 2Z8VA 4UAOA 2Z8WA 4APMA 1HKYA 2QJ4A 2KL5A 2YIOA 3HMSA 5CT3A 5CSQA 2QJ2A 1W81A 1GP9A 4R1BA 3HMRA 4Z0FA 5CS9A 4Z0DA 3SP8A 4IUAA 4R1AA 2LL3A 3HMTA 1GMNA 5I25A 4YIVA 3ZWZA 1I8NA 4UV6A 2Q8BA 1YXEA 3MKPA 1W8KA 4A5TS 2X2ZA 5EOKA 5CS3A 1NK1A 4Z09A 3SRJA 3HN4A 2F83A 2J8LA 5CT2A 5EODA 2Y8RA 3SRIA 4APLA 5CT1A 4YIZA 5CS1A 3ZLEA 2YIPA 2YILA 1BHTA 2Q8AA 4DURA 4Z0EA 1Z40A 4R1CA 2LL4M 5CP9A 2J8JA 1GMOA
chains in the Genus database with same CATH topology
2HGFA 5CS5A 2K13X 5COEA 4R19A 2Z8VA 4UAOA 2Z8WA 4APMA 1HKYA 2QJ4A 2KL5A 2YIOA 3HMSA 5CT3A 5CSQA 2QJ2A 1W81A 1GP9A 4R1BA 3HMRA 4Z0FA 5CS9A 4Z0DA 3SP8A 4IUAA 4R1AA 2LL3A 3HMTA 1GMNA 5I25A 4YIVA 3ZWZA 1I8NA 4UV6A 2Q8BA 1YXEA 3MKPA 1W8KA 4A5TS 2X2ZA 5EOKA 5CS3A 1NK1A 4Z09A 3SRJA 3HN4A 2F83A 2J8LA 5CT2A 5EODA 2Y8RA 3SRIA 4APLA 5CT1A 4YIZA 5CS1A 3ZLEA 2YIPA 2YILA 1BHTA 2Q8AA 4DURA 4Z0EA 1Z40A 4R1CA 2LL4M 5CP9A 2J8JA 1GMOA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2HGF A;  5CS5 A;  2K13 X;  5COE A;  4R19 A;  2Z8V A;  4UAO A;  2Z8W A;  4APM A;  1HKY A;  2QJ4 A;  3HMS A;  2YIO A;  5CT3 A;  5CSQ A;  2QJ2 A;  1W81 A;  1GP9 A;  4R1B A;  3HMR A;  4Z0F A;  5CS9 A;  4Z0D A;  3SP8 A;  4IUA A;  4R1A A;  2LL3 A;  3HMT A;  1GMN A;  5I25 A;  3ZWZ A;  1I8N A;  4UV6 A;  2Q8B A;  1YXE A;  3MKP A;  1W8K A;  4A5T S;  2X2Z A;  5EOK A;  5CS3 A;  1NK1 A;  4Z09 A;  3SRJ A;  3HN4 A;  2F83 A;  2J8L A;  5CT2 A;  5EOD A;  2Y8R A;  3SRI A;  4APL A;  5CT1 A;  5CS1 A;  3ZLE A;  2YIP A;  2YIL A;  1BHT A;  2Q8A A;  4DUR A;  4Z0E A;  1Z40 A;  4R1C A;  2LL4 M;  5CP9 A;  2J8J A;  1GMO A; 
#chains in the Genus database with same CATH topology
 2HGF A;  5CS5 A;  2K13 X;  5COE A;  4R19 A;  2Z8V A;  4UAO A;  2Z8W A;  4APM A;  1HKY A;  2QJ4 A;  2KL5 A;  2YIO A;  3HMS A;  5CT3 A;  5CSQ A;  2QJ2 A;  1W81 A;  1GP9 A;  4R1B A;  3HMR A;  4Z0F A;  5CS9 A;  4Z0D A;  3SP8 A;  4IUA A;  4R1A A;  2LL3 A;  3HMT A;  1GMN A;  5I25 A;  4YIV A;  3ZWZ A;  1I8N A;  4UV6 A;  2Q8B A;  1YXE A;  3MKP A;  1W8K A;  4A5T S;  2X2Z A;  5EOK A;  5CS3 A;  1NK1 A;  4Z09 A;  3SRJ A;  3HN4 A;  2F83 A;  2J8L A;  5CT2 A;  5EOD A;  2Y8R A;  3SRI A;  4APL A;  5CT1 A;  4YIZ A;  5CS1 A;  3ZLE A;  2YIP A;  2YIL A;  1BHT A;  2Q8A A;  4DUR A;  4Z0E A;  1Z40 A;  4R1C A;  2LL4 M;  5CP9 A;  2J8J A;  1GMO A; 
#chains in the Genus database with same CATH homology
 2HGF A;  5CS5 A;  2K13 X;  5COE A;  4R19 A;  2Z8V A;  4UAO A;  2Z8W A;  4APM A;  1HKY A;  2QJ4 A;  2KL5 A;  2YIO A;  3HMS A;  5CT3 A;  5CSQ A;  2QJ2 A;  1W81 A;  1GP9 A;  4R1B A;  3HMR A;  4Z0F A;  5CS9 A;  4Z0D A;  3SP8 A;  4IUA A;  4R1A A;  2LL3 A;  3HMT A;  1GMN A;  5I25 A;  4YIV A;  3ZWZ A;  1I8N A;  4UV6 A;  2Q8B A;  1YXE A;  3MKP A;  1W8K A;  4A5T S;  2X2Z A;  5EOK A;  5CS3 A;  1NK1 A;  4Z09 A;  3SRJ A;  3HN4 A;  2F83 A;  2J8L A;  5CT2 A;  5EOD A;  2Y8R A;  3SRI A;  4APL A;  5CT1 A;  4YIZ A;  5CS1 A;  3ZLE A;  2YIP A;  2YIL A;  1BHT A;  2Q8A A;  4DUR A;  4Z0E A;  1Z40 A;  4R1C A;  2LL4 M;  5CP9 A;  2J8J A;  1GMO A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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