4Z0EA

Crystal structure of fvo strain plasmodium falciparum ama1 in complex with the ron2hp [phe2038trn] peptide
Total Genus 77
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
77
sequence length
331
structure length
270
Chain Sequence
NPWTEYMAKYDIEEVHGSGIRVDLGEDAEVGTQYRLPSGKCPVFGKGIIIETTFLKPVAKDGGFAFPPTNPLISPMTLNGMRDFYKNNEYVKNLDELTLCSRHAGNMNPDNKNSNYKYPAVYDYNDKKCHILYIAAQENNGFCFRPAKDKLFENYTYLSKNVVDNWEEVCPRKNLENAKFGLWVDGNCEDIPHVNEFSANDLFECNKLVFELSASDQPKDRYKSHGKGYNWGNYNRETQKCEIFNVKPTCLINNSSYIATTALSHPIEVE
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule keywords Apical membrane antigen 1
publication title Structure-Activity Studies of beta-Hairpin Peptide Inhibitors of the Plasmodium falciparum AMA1-RON2 Interaction.
pubmed doi rcsb
source organism Plasmodium falciparum vietnam oak-knoll (fvo)
molecule tags Cell invasion
total genus 77
structure length 270
sequence length 331
ec nomenclature
pdb deposition date 2015-03-26
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.50.4.10 Alpha Beta 3-Layer(bba) Sandwich Hepatocyte Growth Factor Hepatocyte Growth Factor 4z0eA01
1BHTA 2LL4M 4Z0EA 3ZLEA 4APMA 5CT1A 5I25A 1YXEA 4APLA 2J8LA 2YILA 3HMRA 5CS3A 2QJ4A 5CS9A 1GMNA 2YIOA 1W81A 5CSQA 4Z09A 1W8KA 2Z8WA 2LL3A 3HMTA 5CS5A 5CT3A 3SRIA 3HN4A 1GMOA 4UV6A 5CS1A 4R1CA 1NK1A 4IUAA 3ZWZA 1I8NA 1GP9A 3HMSA 5CP9A 2K13X 1Z40A 5CT2A 2YIPA 4R19A 4A5TS 2Y8RA 4Z0FA 2F83A 2J8JA 4Z0DA 5EOKA 3SRJA 3MKPA 5EODA 4UAOA 2X2ZA 3SP8A 2Q8AA 4DURA 4R1BA 2Q8BA 2Z8VA 1HKYA 2HGFA 2QJ2A 4R1AA 5COEA
chains in the Genus database with same CATH superfamily
1BHTA 2LL4M 4Z0EA 3ZLEA 4APMA 5CT1A 5I25A 1YXEA 4APLA 2J8LA 2YILA 3HMRA 5CS3A 2QJ4A 5CS9A 1GMNA 2YIOA 1W81A 5CSQA 4Z09A 1W8KA 2Z8WA 2LL3A 3HMTA 5CS5A 5CT3A 3SRIA 3HN4A 1GMOA 4UV6A 5CS1A 4R1CA 1NK1A 4IUAA 3ZWZA 1I8NA 1GP9A 3HMSA 5CP9A 2K13X 1Z40A 5CT2A 2YIPA 4R19A 4A5TS 2Y8RA 4Z0FA 2F83A 2J8JA 4YIZA 4Z0DA 5EOKA 3SRJA 3MKPA 5EODA 4UAOA 2X2ZA 3SP8A 2Q8AA 4DURA 4R1BA 2Q8BA 2Z8VA 4YIVA 1HKYA 2HGFA 2QJ2A 4R1AA 2KL5A 5COEA
chains in the Genus database with same CATH topology
1BHTA 2LL4M 4Z0EA 3ZLEA 4APMA 5CT1A 5I25A 1YXEA 4APLA 2J8LA 2YILA 3HMRA 5CS3A 2QJ4A 5CS9A 1GMNA 2YIOA 1W81A 5CSQA 4Z09A 1W8KA 2Z8WA 2LL3A 3HMTA 5CS5A 5CT3A 3SRIA 3HN4A 1GMOA 4UV6A 5CS1A 4R1CA 1NK1A 4IUAA 3ZWZA 1I8NA 1GP9A 3HMSA 5CP9A 2K13X 1Z40A 5CT2A 2YIPA 4R19A 4A5TS 2Y8RA 4Z0FA 2F83A 2J8JA 4YIZA 4Z0DA 5EOKA 3SRJA 3MKPA 5EODA 4UAOA 2X2ZA 3SP8A 2Q8AA 4DURA 4R1BA 2Q8BA 2Z8VA 4YIVA 1HKYA 2HGFA 2QJ2A 4R1AA 2KL5A 5COEA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1BHT A;  2LL4 M;  4Z0E A;  3ZLE A;  4APM A;  5CT1 A;  5I25 A;  1YXE A;  4APL A;  2J8L A;  2YIL A;  3HMR A;  5CS3 A;  2QJ4 A;  5CS9 A;  1GMN A;  2YIO A;  1W81 A;  5CSQ A;  4Z09 A;  1W8K A;  2Z8W A;  2LL3 A;  3HMT A;  5CS5 A;  5CT3 A;  3SRI A;  3HN4 A;  1GMO A;  4UV6 A;  5CS1 A;  4R1C A;  1NK1 A;  4IUA A;  3ZWZ A;  1I8N A;  1GP9 A;  3HMS A;  5CP9 A;  2K13 X;  1Z40 A;  5CT2 A;  2YIP A;  4R19 A;  4A5T S;  2Y8R A;  4Z0F A;  2F83 A;  2J8J A;  4Z0D A;  5EOK A;  3SRJ A;  3MKP A;  5EOD A;  4UAO A;  2X2Z A;  3SP8 A;  2Q8A A;  4DUR A;  4R1B A;  2Q8B A;  2Z8V A;  1HKY A;  2HGF A;  2QJ2 A;  4R1A A;  5COE A; 
#chains in the Genus database with same CATH topology
 1BHT A;  2LL4 M;  4Z0E A;  3ZLE A;  4APM A;  5CT1 A;  5I25 A;  1YXE A;  4APL A;  2J8L A;  2YIL A;  3HMR A;  5CS3 A;  2QJ4 A;  5CS9 A;  1GMN A;  2YIO A;  1W81 A;  5CSQ A;  4Z09 A;  1W8K A;  2Z8W A;  2LL3 A;  3HMT A;  5CS5 A;  5CT3 A;  3SRI A;  3HN4 A;  1GMO A;  4UV6 A;  5CS1 A;  4R1C A;  1NK1 A;  4IUA A;  3ZWZ A;  1I8N A;  1GP9 A;  3HMS A;  5CP9 A;  2K13 X;  1Z40 A;  5CT2 A;  2YIP A;  4R19 A;  4A5T S;  2Y8R A;  4Z0F A;  2F83 A;  2J8J A;  4YIZ A;  4Z0D A;  5EOK A;  3SRJ A;  3MKP A;  5EOD A;  4UAO A;  2X2Z A;  3SP8 A;  2Q8A A;  4DUR A;  4R1B A;  2Q8B A;  2Z8V A;  4YIV A;  1HKY A;  2HGF A;  2QJ2 A;  4R1A A;  2KL5 A;  5COE A; 
#chains in the Genus database with same CATH homology
 1BHT A;  2LL4 M;  4Z0E A;  3ZLE A;  4APM A;  5CT1 A;  5I25 A;  1YXE A;  4APL A;  2J8L A;  2YIL A;  3HMR A;  5CS3 A;  2QJ4 A;  5CS9 A;  1GMN A;  2YIO A;  1W81 A;  5CSQ A;  4Z09 A;  1W8K A;  2Z8W A;  2LL3 A;  3HMT A;  5CS5 A;  5CT3 A;  3SRI A;  3HN4 A;  1GMO A;  4UV6 A;  5CS1 A;  4R1C A;  1NK1 A;  4IUA A;  3ZWZ A;  1I8N A;  1GP9 A;  3HMS A;  5CP9 A;  2K13 X;  1Z40 A;  5CT2 A;  2YIP A;  4R19 A;  4A5T S;  2Y8R A;  4Z0F A;  2F83 A;  2J8J A;  4YIZ A;  4Z0D A;  5EOK A;  3SRJ A;  3MKP A;  5EOD A;  4UAO A;  2X2Z A;  3SP8 A;  2Q8A A;  4DUR A;  4R1B A;  2Q8B A;  2Z8V A;  4YIV A;  1HKY A;  2HGF A;  2QJ2 A;  4R1A A;  2KL5 A;  5COE A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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