4YIZA

Crystal structure of engineered tgama1 lacking the dii loop in complex with an eimeria tenella ron2d3 peptide
Total Genus 102
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
102
sequence length
399
structure length
392
Chain Sequence
SGNPFQANVEMKTFMERFNLTHHHQSGIYVDLGQDKEVDGTLYREPAGLCPIWGKHIELQQPDRPPYRNNFLEDVPTEKEYKQSGNPLPGGFNLNFVTPSGQRISPFPMELLEKNSNIKASTDLGRCAEFAFKTVAMDKNNKATKYRYPFVYDSKKRLCHILYVSMQLMEGKKYCSVKGEPPDLTWYCFKPRKSVTENHHLIYGSAYVGENPDAFISKCPNQALRGYRFGVWKKGRCLDYTELTDTVIERVESKAQCWVKTFENDGVASDQPDQPHSGGVGRNYGFYYVDTTGEGKCALSDQVPDCLVSDSAAVSYTAAGSLSEETPNFIIPSNPSVTPPTPETALQCTADKFPDSFGACDVQACKRQKTSCVGGQIQSTSVDCTADEQNEC
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

publication title An Extended Surface Loop on Toxoplasma gondii Apical Membrane Antigen 1 (AMA1) Governs Ligand Binding Selectivity.
pubmed doi rcsb
molecule keywords Apical membrane antigen AMA1
molecule tags Immune system
source organism Toxoplasma gondii me49
total genus 102
structure length 392
sequence length 399
chains with identical sequence C, E
ec nomenclature
pdb deposition date 2015-03-02

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF02430 AMA-1 Apical membrane antigen 1
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.10.70.70 Mainly Beta Ribbon Complement Module; domain 1 Complement Module; domain 1 4yizA03
3.50.4.30 Alpha Beta 3-Layer(bba) Sandwich Hepatocyte Growth Factor Hepatocyte Growth Factor 4yizA01
4YIZA 2Y8RA 2X2ZA 2Y8TA 3ZLDA 3ZLEA 4YIVA 4APLA 2Y8SA
chains in the Genus database with same CATH superfamily
2XRBA 2XWBF 3CI0J 3TVJA 2KL5A 1RLHA 5CT1A 2JGXA 1OK2A 4Z0EA 5CS5A 3IU3I 2MCZA 4MUCA 3ZRZA 1UOTP 4B2RA 4A5WB 1NK1A 2CKUA 5COEA 2O39C 4LOTA 4Z09A 4J38B 1O9AA 1G4GA 1TPGA 1OK1A 5DN5A 1TPNA 2LL4M 1Q3XA 1H03P 1QO6A 3O8EB 2Z8WA 2KRIA 3RJ3D 2G7IA 4YNXA 4F4OC 1GP9A 3NJAA 3MQLA 4ONTD 2LOJA 5HYTB 2B5ID 2UWNA 3OEDC 4CSYA 4ZH1D 1GKNA 1H04P 2Y8RA 2KMSA 3WSYA 3ZD1A 5FO8C 1G4FA 1BHTA 1ELVA 1NWVA 3ERBA 4B2SA 4FXGG 1W81A 1YXEA 3T5OA 5I25A 2EHFA 1GPZA 1OJYA 4R1BA 2F83A 2W80A 4A5TS 1E8BA 3ZD2A 2YILA 1HFHA 4YIZA 4AYDA 3HN4A 3VWOA 2K13X 3ZWZA 2ZYCA 2J8JA 5DN4A 3KXVA 2RKYA 2J8LA 2YRAA 3KZJA 1MD8A 2CG6A 2JGWA 2XRDA 1GKGA 3OXUD 1FBRA 3R62A 3HMSA 4DJZA 1ZJKA 5I0QB 2LL3A 3EJHA 4APLA 5CS3A 3K3TA 5HZPB 1E88A 2Z8VA 2MCYA 4UAOA 5CT2A 1MD7A 3ZLDA 5JPMG 4N7EA 1GMOA 3CALA 4R1CA 1GMNA 5CSQA 1VVDA 3FGTA 4PO7A 2HGFA 2RL0A 4BWCA 5CS1A 2XWJI 3NFPI 1CKLA 4AYIA 5CP9A 4JHSA 2YBYA 5HYPA 1TPMA 1SS2A 2BZMA 5HYUB 3WSXA 1VVCA 3IX0A 2YIOA 4Z0FA 4WJG2 2Y8SA 3FGRA 1HKYA 2A55A 4KKDA 3SP8A 1LY2A 4C16A 4R19A 5CT3A 4K12A 1PPQA 2Q8AA 2QJ4A 2RKZA 1QGBA 4APMA 4IGDA 1SRZA 3GXEA 4AYEA 3L89M 1H2QP 3SRIA 2X2ZA 4IUAA 3OP8A 1HCCA 1OJVA 3MKPA 2EC3A 1OK9A 3HMRA 2Q8BA 3HMTA 3GOVA 4UV6A 2I2LA 1HFIA 4R1AA 1GHQB 1U5MA 5EODA 2QY0A 2Y8TA 3ZLEA 2IZ4A 2YIPA 1Z92B 3F6KA 1I8NA 1W8KA 4PZ5A 1E5GA 2IZ3A 2RLPA 1OJWA 4AYMA 2W81A 2WIIC 1Z40A 2QJ2A 2JRAA 4Z0DA 2RLQA 5EOKA 1QUBA 1OK3A 3M7PA 1C1ZA 2CG7A 2XQWC 3SRJA 4DURA 4LOSA 2V8EA 4MSLA 3INBC 4YIVA 3SW0X 1H2PP 2ERJA 5CS9A
chains in the Genus database with same CATH topology
2KL5A 5CT1A 4Z0EA 5CS5A 1NK1A 5COEA 4Z09A 2LL4M 2Z8WA 1GP9A 3NJAA 2Y8RA 3WSYA 1BHTA 1W81A 1YXEA 5I25A 4R1BA 2F83A 4A5TS 2YILA 4YIZA 3HN4A 2K13X 3ZWZA 2J8JA 2J8LA 3HMSA 2LL3A 4APLA 5CS3A 2Z8VA 4UAOA 5CT2A 3ZLDA 4N7EA 1GMOA 4R1CA 1GMNA 5CSQA 3FGTA 4PO7A 2HGFA 4BWCA 5CS1A 5CP9A 3WSXA 2YIOA 4Z0FA 2Y8SA 3FGRA 1HKYA 3SP8A 4R19A 5CT3A 2Q8AA 2QJ4A 4APMA 3SRIA 2X2ZA 4IUAA 3MKPA 2Q8BA 3HMRA 3HMTA 4UV6A 2I2LA 4R1AA 5EODA 2Y8TA 3ZLEA 2YIPA 3F6KA 1I8NA 1W8KA 4Z0DA 1Z40A 2QJ2A 5EOKA 4DURA 3SRJA 4MSLA 4YIVA 5CS9A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4YIZ A;  2Y8R A;  2X2Z A;  2Y8T A;  3ZLD A;  3ZLE A;  4YIV A;  4APL A;  2Y8S A; 
#chains in the Genus database with same CATH topology
 2XRB A;  2XWB F;  3CI0 J;  3TVJ A;  2KL5 A;  1RLH A;  5CT1 A;  2JGX A;  1OK2 A;  4Z0E A;  5CS5 A;  3IU3 I;  2MCZ A;  4MUC A;  3ZRZ A;  1UOT P;  4B2R A;  4A5W B;  1NK1 A;  2CKU A;  5COE A;  2O39 C;  4LOT A;  4Z09 A;  4J38 B;  1O9A A;  1G4G A;  1TPG A;  1OK1 A;  5DN5 A;  1TPN A;  2LL4 M;  1Q3X A;  1H03 P;  1QO6 A;  3O8E B;  2Z8W A;  2KRI A;  3RJ3 D;  2G7I A;  4YNX A;  4F4O C;  1GP9 A;  3NJA A;  3MQL A;  4ONT D;  2LOJ A;  5HYT B;  2B5I D;  2UWN A;  3OED C;  4CSY A;  4ZH1 D;  1GKN A;  1H04 P;  2Y8R A;  2KMS A;  3WSY A;  3ZD1 A;  5FO8 C;  1G4F A;  1BHT A;  1ELV A;  1NWV A;  3ERB A;  4B2S A;  4FXG G;  1W81 A;  1YXE A;  3T5O A;  5I25 A;  2EHF A;  1GPZ A;  1OJY A;  4R1B A;  2F83 A;  2W80 A;  4A5T S;  1E8B A;  3ZD2 A;  2YIL A;  1HFH A;  4YIZ A;  4AYD A;  3HN4 A;  3VWO A;  2K13 X;  3ZWZ A;  2ZYC A;  2J8J A;  5DN4 A;  3KXV A;  2RKY A;  2J8L A;  2YRA A;  3KZJ A;  1MD8 A;  2CG6 A;  2JGW A;  2XRD A;  1GKG A;  3OXU D;  1FBR A;  3R62 A;  3HMS A;  4DJZ A;  1ZJK A;  5I0Q B;  2LL3 A;  3EJH A;  4APL A;  5CS3 A;  3K3T A;  5HZP B;  1E88 A;  2Z8V A;  2MCY A;  4UAO A;  5CT2 A;  1MD7 A;  3ZLD A;  5JPM G;  4N7E A;  1GMO A;  3CAL A;  4R1C A;  1GMN A;  5CSQ A;  1VVD A;  3FGT A;  4PO7 A;  2HGF A;  2RL0 A;  4BWC A;  5CS1 A;  2XWJ I;  3NFP I;  1CKL A;  4AYI A;  5CP9 A;  4JHS A;  2YBY A;  5HYP A;  1TPM A;  1SS2 A;  2BZM A;  5HYU B;  3WSX A;  1VVC A;  3IX0 A;  2YIO A;  4Z0F A;  4WJG 2;  2Y8S A;  3FGR A;  1HKY A;  2A55 A;  4KKD A;  3SP8 A;  1LY2 A;  4C16 A;  4R19 A;  5CT3 A;  4K12 A;  1PPQ A;  2Q8A A;  2QJ4 A;  2RKZ A;  1QGB A;  4APM A;  4IGD A;  1SRZ A;  3GXE A;  4AYE A;  3L89 M;  1H2Q P;  3SRI A;  2X2Z A;  4IUA A;  3OP8 A;  1HCC A;  1OJV A;  3MKP A;  2EC3 A;  1OK9 A;  3HMR A;  2Q8B A;  3HMT A;  3GOV A;  4UV6 A;  2I2L A;  1HFI A;  4R1A A;  1GHQ B;  1U5M A;  5EOD A;  2QY0 A;  2Y8T A;  3ZLE A;  2IZ4 A;  2YIP A;  1Z92 B;  3F6K A;  1I8N A;  1W8K A;  4PZ5 A;  1E5G A;  2IZ3 A;  2RLP A;  1OJW A;  4AYM A;  2W81 A;  2WII C;  1Z40 A;  2QJ2 A;  2JRA A;  4Z0D A;  2RLQ A;  5EOK A;  1QUB A;  1OK3 A;  3M7P A;  1C1Z A;  2CG7 A;  2XQW C;  3SRJ A;  4DUR A;  4LOS A;  2V8E A;  4MSL A;  3INB C;  4YIV A;  3SW0 X;  1H2P P;  2ERJ A;  5CS9 A; 
#chains in the Genus database with same CATH homology
 2KL5 A;  5CT1 A;  4Z0E A;  5CS5 A;  1NK1 A;  5COE A;  4Z09 A;  2LL4 M;  2Z8W A;  1GP9 A;  3NJA A;  2Y8R A;  3WSY A;  1BHT A;  1W81 A;  1YXE A;  5I25 A;  4R1B A;  2F83 A;  4A5T S;  2YIL A;  4YIZ A;  3HN4 A;  2K13 X;  3ZWZ A;  2J8J A;  2J8L A;  3HMS A;  2LL3 A;  4APL A;  5CS3 A;  2Z8V A;  4UAO A;  5CT2 A;  3ZLD A;  4N7E A;  1GMO A;  4R1C A;  1GMN A;  5CSQ A;  3FGT A;  4PO7 A;  2HGF A;  4BWC A;  5CS1 A;  5CP9 A;  3WSX A;  2YIO A;  4Z0F A;  2Y8S A;  3FGR A;  1HKY A;  3SP8 A;  4R19 A;  5CT3 A;  2Q8A A;  2QJ4 A;  4APM A;  3SRI A;  2X2Z A;  4IUA A;  3MKP A;  2Q8B A;  3HMR A;  3HMT A;  4UV6 A;  2I2L A;  4R1A A;  5EOD A;  2Y8T A;  3ZLE A;  2YIP A;  3F6K A;  1I8N A;  1W8K A;  4Z0D A;  1Z40 A;  2QJ2 A;  5EOK A;  4DUR A;  3SRJ A;  4MSL A;  4YIV A;  5CS9 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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#similar chains, but unknotted
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