4APLA

Crystal structure of ama1 from neospora caninum
Total Genus 104
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
104
sequence length
412
structure length
398
Chain Sequence
TPQNPFQTPELKAFLERYNVTLHHQSGVNVDLGQDKEVDGKLYREAAGLCPVWGKYIQLHQPNRPPYKNNFLEDIPTEAEYQKSGNPLPGGFNMNFVTPAGQRISPYPMELLEKSSKIKASTELGKCAEFAYKTTAMDKSNQATQYRYPFVYDSKRRLCYILSVSMQRMEGSKYCSTNDDPVNLTWYCFEPQKSPTANHNLIFGSAYVGKDPDAFLTKCPNQALKGYRFGHWTNGRCHDYTELADSWIEAVDSKAQCWVKTFTNDEVASDQPRTHSWNDWWPVHEKDQPHSGGDGRNYGFFYFDSNGKGKCALSHKAPDCLVSDSKAVSYTALGSLSEETPDIIIPSNDEALQCRSSEFPETFGSCDVQACKRQKTSCVGGQIQSTSVDCTAEEQNDC
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Babesia Divergens and Neospora Caninum Apical Membrane Antigen 1 (Ama1) Structures Reveal Selectivity and Plasticity in Apicomplexan Parasite Host Cell Invasion.
pubmed doi rcsb
molecule keywords APICAL MEMBRANE ANTIGEN 1
molecule tags Membrane protein
source organism Neospora caninum
total genus 104
structure length 398
sequence length 412
chains with identical sequence B, D, E
ec nomenclature
pdb deposition date 2012-04-04

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF02430 AMA-1 Apical membrane antigen 1
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.10.70.70 Mainly Beta Ribbon Complement Module; domain 1 Complement Module; domain 1 4aplA03
3.50.4.10 Alpha Beta 3-Layer(bba) Sandwich Hepatocyte Growth Factor Hepatocyte Growth Factor 4aplA01
1W8KA 2Q8BA 5CT1A 2K13X 1GP9A 2YIPA 3HN4A 3HMTA 4R1AA 5CT3A 3SRIA 4UV6A 3HMSA 4Z0DA 1W81A 2Y8RA 5CSQA 2F83A 4UAOA 2QJ2A 2YILA 4R1BA 5CT2A 1HKYA 5COEA 3SP8A 3ZLEA 5CS9A 2YIOA 4A5TS 1BHTA 3SRJA 3ZWZA 2Y8TA 5CS5A 2HGFA 4DURA 1GMNA 4Z0FA 4APMA 4APLA 5EOKA 5CP9A 4IUAA 1Z40A 1NK1A 4R19A 2X2ZA 4R1CA 5CS3A 2Z8WA 1I8NA 1GMOA 2Q8AA 1YXEA 4Z09A 2LL4M 3ZLDA 2J8LA 2LL3A 3HMRA 5CS1A 2J8JA 2Y8SA 5I25A 2QJ4A 2Z8VA 4Z0EA 3MKPA 5EODA 4YIZA
chains in the Genus database with same CATH superfamily
5HYTB 1CKLA 2IZ3A 3INBC 2RKYA 2V8EA 3SRIA 4UV6A 4Z0DA 1G4FA 1OJYA 4AYDA 2EC3A 2YILA 4R1BA 5COEA 3IU3I 3ZLEA 2JRAA 4A5TS 1BHTA 1H03P 2A55A 2CG6A 1QGBA 3SRJA 2Y8TA 5CS5A 4YIVA 3NJAA 4YNXA 3ZWZA 4APMA 4JHSA 4IUAA 1H2QP 1NK1A 1VVCA 2X2ZA 3GXEA 1GKGA 1SS2A 1ELVA 4ZH1D 4B2SA 4Z09A 3HMRA 4LOTA 3T5OA 2Y8SA 4MSLA 1E88A 2QJ4A 2LOJA 4AYEA 4AYIA 1Z92B 4UAOA 4C16A 3FGRA 1GKNA 1GP9A 4F4OC 2YIPA 3HMTA 4R1AA 2RLPA 3FGTA 2W81A 3GOVA 3OXUD 5HYUB 3SP8A 1H2PP 2YIOA 4KKDA 5HZPB 4DURA 2CKUA 4Z0FA 3ZD1A 1PPQA 1SRZA 4APLA 1U5MA 2XWBF 5JPMG 5CS3A 2WIIC 1MD7A 3WSYA 3L89M 4LOSA 2MCYA 3EJHA 1QO6A 4B2RA 3KZJA 2LL4M 2J8LA 1TPMA 2LL3A 1HCCA 2J8JA 3MQLA 5I0QB 2MCZA 3MKPA 3OEDC 1QUBA 4A5WB 4YIZA 1VVDA 2RL0A 2Q8BA 1GHQB 2RLQA 2KL5A 3HMSA 3ZD2A 3K3TA 1W81A 5CSQA 3VWOA 2JGWA 3R62A 1E5GA 3OP8A 2W80A 2XRDA 2QJ2A 5HYPA 1OJVA 1OK1A 2B5ID 4IGDA 2G7IA 2HGFA 1GMNA 4BWCA 3WSXA 2EHFA 1MD8A 1HFHA 1OK3A 2YBYA 1O9AA 2IZ4A 5DN5A 3CI0J 1Z40A 4R19A 2QY0A 4PZ5A 2KRIA 2Z8WA 1I8NA 4AYMA 1YXEA 3O8EB 4PO7A 1OK9A 3ZLDA 2KMSA 2Z8VA 1LY2A 5EODA 1OJWA 1TPGA 1W8KA 5CT1A 2K13X 4CSYA 2UWNA 3HN4A 2BZMA 3ZRZA 5CT3A 1RLHA 1ZJKA 2ERJA 2O39C 3RJ3D 2Y8RA 3KXVA 2I2LA 4K12A 2F83A 5CT2A 1HKYA 2CG7A 3CALA 2XWJI 5CS9A 4DJZA 1H04P 1FBRA 2YRAA 3SW0X 2JGXA 1Q3XA 3IX0A 4J38B 1TPNA 1HFIA 5EOKA 1OK2A 4MUCA 5DN4A 2RKZA 5CP9A 4R1CA 1GPZA 1GMOA 2Q8AA 3NFPI 3TVJA 4N7EA 4WJG2 4ONTD 1UOTP 4FXGG 1E8BA 2ZYCA 3M7PA 5CS1A 1G4GA 3F6KA 5I25A 4Z0EA 5FO8C 1C1ZA 2XQWC 2XRBA 1NWVA 3ERBA
chains in the Genus database with same CATH topology
3SRIA 4UV6A 4Z0DA 2YILA 4R1BA 5COEA 3ZLEA 4A5TS 1BHTA 3SRJA 3ZWZA 2Y8TA 5CS5A 3NJAA 4APMA 4IUAA 1NK1A 2X2ZA 4Z09A 3HMRA 2Y8SA 4MSLA 2QJ4A 4UAOA 3FGRA 1GP9A 2YIPA 3HMTA 4R1AA 3FGTA 3SP8A 2YIOA 4DURA 4Z0FA 4APLA 5CS3A 3WSYA 2LL4M 2J8LA 2LL3A 2J8JA 3MKPA 4YIZA 2Q8BA 2KL5A 3HMSA 1W81A 5CSQA 2QJ2A 2HGFA 1GMNA 4BWCA 3WSXA 4YIVA 1Z40A 4R19A 2Z8WA 1I8NA 1YXEA 4PO7A 3ZLDA 2Z8VA 5EODA 1W8KA 5CT1A 2K13X 3HN4A 5CT3A 2Y8RA 2I2LA 2F83A 5CT2A 1HKYA 5CS9A 5EOKA 5CP9A 4R1CA 1GMOA 2Q8AA 4N7EA 5CS1A 3F6KA 5I25A 4Z0EA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1W8K A;  2Q8B A;  5CT1 A;  2K13 X;  1GP9 A;  2YIP A;  3HN4 A;  3HMT A;  4R1A A;  5CT3 A;  3SRI A;  4UV6 A;  3HMS A;  4Z0D A;  1W81 A;  2Y8R A;  5CSQ A;  2F83 A;  4UAO A;  2QJ2 A;  2YIL A;  4R1B A;  5CT2 A;  1HKY A;  5COE A;  3SP8 A;  3ZLE A;  5CS9 A;  2YIO A;  4A5T S;  1BHT A;  3SRJ A;  3ZWZ A;  2Y8T A;  5CS5 A;  2HGF A;  4DUR A;  1GMN A;  4Z0F A;  4APM A;  4APL A;  5EOK A;  5CP9 A;  4IUA A;  1Z40 A;  1NK1 A;  4R19 A;  2X2Z A;  4R1C A;  5CS3 A;  2Z8W A;  1I8N A;  1GMO A;  2Q8A A;  1YXE A;  4Z09 A;  2LL4 M;  3ZLD A;  2J8L A;  2LL3 A;  3HMR A;  5CS1 A;  2J8J A;  2Y8S A;  5I25 A;  2QJ4 A;  2Z8V A;  4Z0E A;  3MKP A;  5EOD A;  4YIZ A; 
#chains in the Genus database with same CATH topology
 5HYT B;  1CKL A;  2IZ3 A;  3INB C;  2RKY A;  2V8E A;  3SRI A;  4UV6 A;  4Z0D A;  1G4F A;  1OJY A;  4AYD A;  2EC3 A;  2YIL A;  4R1B A;  5COE A;  3IU3 I;  3ZLE A;  2JRA A;  4A5T S;  1BHT A;  1H03 P;  2A55 A;  2CG6 A;  1QGB A;  3SRJ A;  2Y8T A;  5CS5 A;  4YIV A;  3NJA A;  4YNX A;  3ZWZ A;  4APM A;  4JHS A;  4IUA A;  1H2Q P;  1NK1 A;  1VVC A;  2X2Z A;  3GXE A;  1GKG A;  1SS2 A;  1ELV A;  4ZH1 D;  4B2S A;  4Z09 A;  3HMR A;  4LOT A;  3T5O A;  2Y8S A;  4MSL A;  1E88 A;  2QJ4 A;  2LOJ A;  4AYE A;  4AYI A;  1Z92 B;  4UAO A;  4C16 A;  3FGR A;  1GKN A;  1GP9 A;  4F4O C;  2YIP A;  3HMT A;  4R1A A;  2RLP A;  3FGT A;  2W81 A;  3GOV A;  3OXU D;  5HYU B;  3SP8 A;  1H2P P;  2YIO A;  4KKD A;  5HZP B;  4DUR A;  2CKU A;  4Z0F A;  3ZD1 A;  1PPQ A;  1SRZ A;  4APL A;  1U5M A;  2XWB F;  5JPM G;  5CS3 A;  2WII C;  1MD7 A;  3WSY A;  3L89 M;  4LOS A;  2MCY A;  3EJH A;  1QO6 A;  4B2R A;  3KZJ A;  2LL4 M;  2J8L A;  1TPM A;  2LL3 A;  1HCC A;  2J8J A;  3MQL A;  5I0Q B;  2MCZ A;  3MKP A;  3OED C;  1QUB A;  4A5W B;  4YIZ A;  1VVD A;  2RL0 A;  2Q8B A;  1GHQ B;  2RLQ A;  2KL5 A;  3HMS A;  3ZD2 A;  3K3T A;  1W81 A;  5CSQ A;  3VWO A;  2JGW A;  3R62 A;  1E5G A;  3OP8 A;  2W80 A;  2XRD A;  2QJ2 A;  5HYP A;  1OJV A;  1OK1 A;  2B5I D;  4IGD A;  2G7I A;  2HGF A;  1GMN A;  4BWC A;  3WSX A;  2EHF A;  1MD8 A;  1HFH A;  1OK3 A;  2YBY A;  1O9A A;  2IZ4 A;  5DN5 A;  3CI0 J;  1Z40 A;  4R19 A;  2QY0 A;  4PZ5 A;  2KRI A;  2Z8W A;  1I8N A;  4AYM A;  1YXE A;  3O8E B;  4PO7 A;  1OK9 A;  3ZLD A;  2KMS A;  2Z8V A;  1LY2 A;  5EOD A;  1OJW A;  1TPG A;  1W8K A;  5CT1 A;  2K13 X;  4CSY A;  2UWN A;  3HN4 A;  2BZM A;  3ZRZ A;  5CT3 A;  1RLH A;  1ZJK A;  2ERJ A;  2O39 C;  3RJ3 D;  2Y8R A;  3KXV A;  2I2L A;  4K12 A;  2F83 A;  5CT2 A;  1HKY A;  2CG7 A;  3CAL A;  2XWJ I;  5CS9 A;  4DJZ A;  1H04 P;  1FBR A;  2YRA A;  3SW0 X;  2JGX A;  1Q3X A;  3IX0 A;  4J38 B;  1TPN A;  1HFI A;  5EOK A;  1OK2 A;  4MUC A;  5DN4 A;  2RKZ A;  5CP9 A;  4R1C A;  1GPZ A;  1GMO A;  2Q8A A;  3NFP I;  3TVJ A;  4N7E A;  4WJG 2;  4ONT D;  1UOT P;  4FXG G;  1E8B A;  2ZYC A;  3M7P A;  5CS1 A;  1G4G A;  3F6K A;  5I25 A;  4Z0E A;  5FO8 C;  1C1Z A;  2XQW C;  2XRB A;  1NWV A;  3ERB A; 
#chains in the Genus database with same CATH homology
 3SRI A;  4UV6 A;  4Z0D A;  2YIL A;  4R1B A;  5COE A;  3ZLE A;  4A5T S;  1BHT A;  3SRJ A;  3ZWZ A;  2Y8T A;  5CS5 A;  3NJA A;  4APM A;  4IUA A;  1NK1 A;  2X2Z A;  4Z09 A;  3HMR A;  2Y8S A;  4MSL A;  2QJ4 A;  4UAO A;  3FGR A;  1GP9 A;  2YIP A;  3HMT A;  4R1A A;  3FGT A;  3SP8 A;  2YIO A;  4DUR A;  4Z0F A;  4APL A;  5CS3 A;  3WSY A;  2LL4 M;  2J8L A;  2LL3 A;  2J8J A;  3MKP A;  4YIZ A;  2Q8B A;  2KL5 A;  3HMS A;  1W81 A;  5CSQ A;  2QJ2 A;  2HGF A;  1GMN A;  4BWC A;  3WSX A;  4YIV A;  1Z40 A;  4R19 A;  2Z8W A;  1I8N A;  1YXE A;  4PO7 A;  3ZLD A;  2Z8V A;  5EOD A;  1W8K A;  5CT1 A;  2K13 X;  3HN4 A;  5CT3 A;  2Y8R A;  2I2L A;  2F83 A;  5CT2 A;  1HKY A;  5CS9 A;  5EOK A;  5CP9 A;  4R1C A;  1GMO A;  2Q8A A;  4N7E A;  5CS1 A;  3F6K A;  5I25 A;  4Z0E A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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