2Y8RA

Crystal structure of apo ama1 mutant (tyr230ala) from toxoplasma gondii
Total Genus 91
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
91
sequence length
412
structure length
399
Chain Sequence
SGNPFQANVEMKTFMERFNLTHHHQSGIYVDLGQDKEVDGTLYREPAGLCPIWGKHIELQQPDRPPYRNNFLEDVPTEKEYKQSGNPLPGGFNLNFVTPSGQRISPFPMELLEKNSNIKASTDLGRCAEFAFKTVKATKYRYPFVYDSKKRLCHILAVSMQLMEGKKYCSVKGEPPDLTWYCFKPRKSVTENHHLIYGSAYVGENPDAFISKCPNQALRGYRFGVWKKGRCLDYTELTDTVIERVESKAQCWVKTFENDGVASDQPLTSQASWNDWWPLHQSDQPHSGGVGRNYGFYYVDTTGEGKCALSDQVPDCLVSDSAAVSYTAAGSLSEETPNFIIPSNTPPTPETALQCTADKFPDSFGACDVQACKRQKTSCVGGQIQSTSVDCTADEQNEC
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Host Cell Invasion by Apicomplexan Parasites: Insights from the Co-Structure of Ama1 with a Ron2 Peptide
pubmed doi rcsb
molecule tags Membrane protein
source organism Toxoplasma gondii
molecule keywords APICAL MEMBRANE ANTIGEN, PUTATIVE
total genus 91
structure length 399
sequence length 412
chains with identical sequence B, D, E
ec nomenclature
pdb deposition date 2011-02-10

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF02430 AMA-1 Apical membrane antigen 1
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.10.70.70 Mainly Beta Ribbon Complement Module; domain 1 Complement Module; domain 1 2y8rA03
3.50.4.10 Alpha Beta 3-Layer(bba) Sandwich Hepatocyte Growth Factor Hepatocyte Growth Factor 2y8rA01
2YIOA 5I25A 1HKYA 4YIZA 4IUAA 5CS5A 4Z0DA 2LL4M 2Z8WA 1GP9A 3SP8A 3SRIA 4Z0FA 1W8KA 3HN4A 5EOKA 2Y8RA 2Y8TA 2YIPA 2F83A 5CS3A 5CSQA 2K13X 1Z40A 1NK1A 3ZLDA 2Z8VA 3HMTA 3ZLEA 4R19A 2LL3A 3HMRA 4UV6A 3HMSA 5EODA 1BHTA 3SRJA 2J8JA 2Q8AA 5CT1A 4Z09A 4A5TS 3MKPA 2QJ4A 5COEA 2Y8SA 2J8LA 4R1AA 5CT3A 5CS9A 4Z0EA 2YILA 5CP9A 4UAOA 5CS1A 4APMA 2QJ2A 4DURA 2Q8BA 1GMOA 4R1BA 5CT2A 2X2ZA 4APLA 1YXEA 4R1CA 1GMNA 2HGFA 3ZWZA 1I8NA 1W81A
chains in the Genus database with same CATH superfamily
5I0QB 4UV6A 1PPQA 5CS5A 1HKYA 3ZRZA 1OK3A 2LL4M 4PZ5A 3HN4A 3IU3I 2Y8TA 2K13X 1G4GA 1NK1A 3NJAA 3HMTA 1O9AA 1H04P 3O8EB 4LOSA 2RLQA 2XWBF 2MCYA 3WSXA 1SRZA 4LOTA 4YIVA 5EODA 2KRIA 2J8LA 1FBRA 4Z0EA 3WSYA 1E88A 5HYTB 5CS1A 3CI0J 5CT2A 1C1ZA 3CALA 2KMSA 2HGFA 3INBC 3HMRA 1ELVA 4N7EA 4DJZA 5HZPB 5JPMG 5I25A 1NWVA 4AYMA 4F4OC 1UOTP 1GP9A 3SRIA 1TPNA 3FGTA 3L89M 2RLPA 5HYUB 3MQLA 3K3TA 4YNXA 2O39C 2RKZA 1VVDA 3ZD1A 2B5ID 1GHQB 2W80A 3ZLDA 2ZYCA 1QGBA 3ZLEA 4R19A 2LL3A 4AYDA 1BHTA 5DN4A 2J8JA 4FXGG 4MUCA 3ZD2A 1OK1A 3MKPA 5COEA 4R1AA 1TPGA 2XRBA 4C16A 1E8BA 4PO7A 4ZH1D 1G4FA 4UAOA 5CS9A 4B2SA 3OXUD 4APMA 1OK2A 5HYPA 2IZ4A 2UWNA 2CG6A 2LOJA 1YXEA 1E5GA 1GMNA 3R62A 4KKDA 1HFHA 3TVJA 4CSYA 1H2PP 1OJYA 1CKLA 3NFPI 4YIZA 3SP8A 1MD8A 2Z8WA 4ONTD 2JGXA 1Z92B 2EHFA 5EOKA 2RL0A 2WIIC 2Y8RA 3EJHA 4A5WB 2YIPA 5CSQA 1QO6A 2I2LA 1SS2A 2Z8VA 3F6KA 1GKGA 1U5MA 5DN5A 2EC3A 1ZJKA 2Q8AA 3FGRA 4Z09A 5CT1A 3VWOA 4A5TS 2QJ4A 1H2QP 3GOVA 4JHSA 3RJ3D 1Q3XA 4AYIA 2QJ2A 4DURA 2W81A 1GMOA 4J38B 2XWJI 4MSLA 4R1BA 4APLA 4BWCA 2RKYA 2V8EA 1OK9A 2A55A 1QUBA 4K12A 1I8NA 3ZWZA 2YIOA 1OJVA 4IUAA 4Z0DA 1W8KA 1GPZA 2IZ3A 1HFIA 1OJWA 2JGWA 3ERBA 4IGDA 2F83A 5CS3A 1Z40A 3KZJA 1LY2A 3M7PA 1RLHA 3OEDC 2CG7A 3IX0A 3HMSA 2KL5A 3SRJA 1TPMA 3T5OA 2ERJA 1HCCA 2Y8SA 1H03P 5CT3A 1VVCA 2QY0A 3KXVA 2YILA 2YBYA 5CP9A 2BZMA 3OP8A 4AYEA 2Q8BA 1MD7A 2MCZA 4WJG2 1GKNA 2X2ZA 4R1CA 4B2RA 2JRAA 2XQWC 2CKUA 5FO8C 3SW0X 3GXEA 2G7IA 2XRDA 4Z0FA 2YRAA 1W81A
chains in the Genus database with same CATH topology
1HKYA 5CS5A 2LL4M 3HN4A 2Y8TA 2K13X 1NK1A 3NJAA 3HMTA 4UV6A 3WSXA 5EODA 4YIVA 2J8LA 4Z0EA 3WSYA 5CS1A 5CT2A 3HMRA 2HGFA 4N7EA 5I25A 3SRIA 1GP9A 3FGTA 3ZLDA 3ZLEA 4R19A 2LL3A 1BHTA 2J8JA 3MKPA 5COEA 4R1AA 5CS9A 4PO7A 4UAOA 4APMA 1YXEA 1GMNA 4YIZA 3SP8A 2Z8WA 5EOKA 2Y8RA 2YIPA 5CSQA 2I2LA 2Z8VA 3F6KA 2Q8AA 5CT1A 3FGRA 4Z09A 4A5TS 2QJ4A 2QJ2A 4DURA 1GMOA 4MSLA 4R1BA 4APLA 4BWCA 3ZWZA 1I8NA 2YIOA 4IUAA 4Z0DA 1W8KA 5CS3A 2F83A 1Z40A 3HMSA 2KL5A 3SRJA 2Y8SA 5CT3A 2YILA 5CP9A 2Q8BA 2X2ZA 4R1CA 4Z0FA 1W81A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2YIO A;  5I25 A;  1HKY A;  4YIZ A;  4IUA A;  5CS5 A;  4Z0D A;  2LL4 M;  2Z8W A;  1GP9 A;  3SP8 A;  3SRI A;  4Z0F A;  1W8K A;  3HN4 A;  5EOK A;  2Y8R A;  2Y8T A;  2YIP A;  2F83 A;  5CS3 A;  5CSQ A;  2K13 X;  1Z40 A;  1NK1 A;  3ZLD A;  2Z8V A;  3HMT A;  3ZLE A;  4R19 A;  2LL3 A;  3HMR A;  4UV6 A;  3HMS A;  5EOD A;  1BHT A;  3SRJ A;  2J8J A;  2Q8A A;  5CT1 A;  4Z09 A;  4A5T S;  3MKP A;  2QJ4 A;  5COE A;  2Y8S A;  2J8L A;  4R1A A;  5CT3 A;  5CS9 A;  4Z0E A;  2YIL A;  5CP9 A;  4UAO A;  5CS1 A;  4APM A;  2QJ2 A;  4DUR A;  2Q8B A;  1GMO A;  4R1B A;  5CT2 A;  2X2Z A;  4APL A;  1YXE A;  4R1C A;  1GMN A;  2HGF A;  3ZWZ A;  1I8N A;  1W81 A; 
#chains in the Genus database with same CATH topology
 5I0Q B;  4UV6 A;  1PPQ A;  5CS5 A;  1HKY A;  3ZRZ A;  1OK3 A;  2LL4 M;  4PZ5 A;  3HN4 A;  3IU3 I;  2Y8T A;  2K13 X;  1G4G A;  1NK1 A;  3NJA A;  3HMT A;  1O9A A;  1H04 P;  3O8E B;  4LOS A;  2RLQ A;  2XWB F;  2MCY A;  3WSX A;  1SRZ A;  4LOT A;  4YIV A;  5EOD A;  2KRI A;  2J8L A;  1FBR A;  4Z0E A;  3WSY A;  1E88 A;  5HYT B;  5CS1 A;  3CI0 J;  5CT2 A;  1C1Z A;  3CAL A;  2KMS A;  2HGF A;  3INB C;  3HMR A;  1ELV A;  4N7E A;  4DJZ A;  5HZP B;  5JPM G;  5I25 A;  1NWV A;  4AYM A;  4F4O C;  1UOT P;  1GP9 A;  3SRI A;  1TPN A;  3FGT A;  3L89 M;  2RLP A;  5HYU B;  3MQL A;  3K3T A;  4YNX A;  2O39 C;  2RKZ A;  1VVD A;  3ZD1 A;  2B5I D;  1GHQ B;  2W80 A;  3ZLD A;  2ZYC A;  1QGB A;  3ZLE A;  4R19 A;  2LL3 A;  4AYD A;  1BHT A;  5DN4 A;  2J8J A;  4FXG G;  4MUC A;  3ZD2 A;  1OK1 A;  3MKP A;  5COE A;  4R1A A;  1TPG A;  2XRB A;  4C16 A;  1E8B A;  4PO7 A;  4ZH1 D;  1G4F A;  4UAO A;  5CS9 A;  4B2S A;  3OXU D;  4APM A;  1OK2 A;  5HYP A;  2IZ4 A;  2UWN A;  2CG6 A;  2LOJ A;  1YXE A;  1E5G A;  1GMN A;  3R62 A;  4KKD A;  1HFH A;  3TVJ A;  4CSY A;  1H2P P;  1OJY A;  1CKL A;  3NFP I;  4YIZ A;  3SP8 A;  1MD8 A;  2Z8W A;  4ONT D;  2JGX A;  1Z92 B;  2EHF A;  5EOK A;  2RL0 A;  2WII C;  2Y8R A;  3EJH A;  4A5W B;  2YIP A;  5CSQ A;  1QO6 A;  2I2L A;  1SS2 A;  2Z8V A;  3F6K A;  1GKG A;  1U5M A;  5DN5 A;  2EC3 A;  1ZJK A;  2Q8A A;  3FGR A;  4Z09 A;  5CT1 A;  3VWO A;  4A5T S;  2QJ4 A;  1H2Q P;  3GOV A;  4JHS A;  3RJ3 D;  1Q3X A;  4AYI A;  2QJ2 A;  4DUR A;  2W81 A;  1GMO A;  4J38 B;  2XWJ I;  4MSL A;  4R1B A;  4APL A;  4BWC A;  2RKY A;  2V8E A;  1OK9 A;  2A55 A;  1QUB A;  4K12 A;  1I8N A;  3ZWZ A;  2YIO A;  1OJV A;  4IUA A;  4Z0D A;  1W8K A;  1GPZ A;  2IZ3 A;  1HFI A;  1OJW A;  2JGW A;  3ERB A;  4IGD A;  2F83 A;  5CS3 A;  1Z40 A;  3KZJ A;  1LY2 A;  3M7P A;  1RLH A;  3OED C;  2CG7 A;  3IX0 A;  3HMS A;  2KL5 A;  3SRJ A;  1TPM A;  3T5O A;  2ERJ A;  1HCC A;  2Y8S A;  1H03 P;  5CT3 A;  1VVC A;  2QY0 A;  3KXV A;  2YIL A;  2YBY A;  5CP9 A;  2BZM A;  3OP8 A;  4AYE A;  2Q8B A;  1MD7 A;  2MCZ A;  4WJG 2;  1GKN A;  2X2Z A;  4R1C A;  4B2R A;  2JRA A;  2XQW C;  2CKU A;  5FO8 C;  3SW0 X;  3GXE A;  2G7I A;  2XRD A;  4Z0F A;  2YRA A;  1W81 A; 
#chains in the Genus database with same CATH homology
 1HKY A;  5CS5 A;  2LL4 M;  3HN4 A;  2Y8T A;  2K13 X;  1NK1 A;  3NJA A;  3HMT A;  4UV6 A;  3WSX A;  5EOD A;  4YIV A;  2J8L A;  4Z0E A;  3WSY A;  5CS1 A;  5CT2 A;  3HMR A;  2HGF A;  4N7E A;  5I25 A;  3SRI A;  1GP9 A;  3FGT A;  3ZLD A;  3ZLE A;  4R19 A;  2LL3 A;  1BHT A;  2J8J A;  3MKP A;  5COE A;  4R1A A;  5CS9 A;  4PO7 A;  4UAO A;  4APM A;  1YXE A;  1GMN A;  4YIZ A;  3SP8 A;  2Z8W A;  5EOK A;  2Y8R A;  2YIP A;  5CSQ A;  2I2L A;  2Z8V A;  3F6K A;  2Q8A A;  5CT1 A;  3FGR A;  4Z09 A;  4A5T S;  2QJ4 A;  2QJ2 A;  4DUR A;  1GMO A;  4MSL A;  4R1B A;  4APL A;  4BWC A;  3ZWZ A;  1I8N A;  2YIO A;  4IUA A;  4Z0D A;  1W8K A;  5CS3 A;  2F83 A;  1Z40 A;  3HMS A;  2KL5 A;  3SRJ A;  2Y8S A;  5CT3 A;  2YIL A;  5CP9 A;  2Q8B A;  2X2Z A;  4R1C A;  4Z0F A;  1W81 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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