4YIVA

Crystal structure of engineered tgama1 lacking the dii loop
Total Genus 101
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
101
sequence length
388
structure length
374
Chain Sequence
GNPFQANVEMKTFMERFNLTHHHQSGIYVDLGQDKEVDGTLYREPAGLCPIWGKHIELQQPDRPPYRNNFLEDVPTEKEYKQSGNPLPGGFNLNFVTPSGQRISPFPMELLEKNSNIKASTDLGRCAEFAFKTVAMDKNNKATKYRYPFVYDSKKRLCHILYVSMQLMEGKKYCSVKGEPPDLTWYCFKPRKSVTENHHLIYGSAYVGENPDAFISKCPNQALRGYRFGVWKKGRCLDYTELTDTVIERVESKAQCWVKTFENDGVASDQPGQPHSGGVGRNYGFYYVDTTGEGKCALSDQVPDCLVSDSAAVSYTAAGSLSEETPNFIIPSNPSVTPPTTALQCPDSFGACDVQACKRQKTSCVGGQIQSTSV
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title An Extended Surface Loop on Toxoplasma gondii Apical Membrane Antigen 1 (AMA1) Governs Ligand Binding Selectivity.
pubmed doi rcsb
molecule tags Immune system
source organism Toxoplasma gondii me49
molecule keywords Apical membrane antigen AMA1
total genus 101
structure length 374
sequence length 388
ec nomenclature
pdb deposition date 2015-03-02

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF02430 AMA-1 Apical membrane antigen 1
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.50.4.30 Alpha Beta 3-Layer(bba) Sandwich Hepatocyte Growth Factor Hepatocyte Growth Factor 4yivA01
4YIVA 4YIZA
chains in the Genus database with same CATH superfamily
1BHTA 2HGFA 1NK1A 1YXEA 2Q8BA 1HKYA 2LL4M 3HMSA 2LL3A 5EOKA 2K13X 5EODA 1Z40A 4R1AA 3ZWZA 1GMOA 4R19A 1W81A 1W8KA 4UAOA 2QJ4A 5CS9A 4Z09A 2J8LA 4Z0DA 4IUAA 3ZLEA 3HN4A 2KL5A 4DURA 4R1BA 3SP8A 4YIZA 5CS5A 1I8NA 2Z8VA 5COEA 2YILA 5CS1A 3HMRA 2Z8WA 5CP9A 5CT3A 4APMA 2Q8AA 4Z0FA 2F83A 2X2ZA 2Y8RA 5CT2A 4R1CA 2YIPA 4A5TS 1GP9A 5I25A 2QJ2A 3SRIA 3SRJA 1GMNA 4YIVA 5CT1A 2J8JA 4APLA 4UV6A 3HMTA 5CS3A 4Z0EA 2YIOA 5CSQA 3MKPA
chains in the Genus database with same CATH topology
1BHTA 2HGFA 1NK1A 1YXEA 2Q8BA 1HKYA 2LL4M 3HMSA 2LL3A 5EOKA 2K13X 5EODA 1Z40A 4R1AA 3ZWZA 1GMOA 4R19A 1W81A 1W8KA 4UAOA 2QJ4A 5CS9A 4Z09A 2J8LA 4Z0DA 4IUAA 3ZLEA 3HN4A 2KL5A 4DURA 4R1BA 3SP8A 4YIZA 5CS5A 1I8NA 2Z8VA 5COEA 2YILA 5CS1A 3HMRA 2Z8WA 5CP9A 5CT3A 4APMA 2Q8AA 4Z0FA 2F83A 2X2ZA 2Y8RA 5CT2A 4R1CA 2YIPA 4A5TS 1GP9A 5I25A 2QJ2A 3SRIA 3SRJA 1GMNA 4YIVA 5CT1A 2J8JA 4APLA 4UV6A 3HMTA 5CS3A 4Z0EA 2YIOA 5CSQA 3MKPA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4YIV A;  4YIZ A; 
#chains in the Genus database with same CATH topology
 1BHT A;  2HGF A;  1NK1 A;  1YXE A;  2Q8B A;  1HKY A;  2LL4 M;  3HMS A;  2LL3 A;  5EOK A;  2K13 X;  5EOD A;  1Z40 A;  4R1A A;  3ZWZ A;  1GMO A;  4R19 A;  1W81 A;  1W8K A;  4UAO A;  2QJ4 A;  5CS9 A;  4Z09 A;  2J8L A;  4Z0D A;  4IUA A;  3ZLE A;  3HN4 A;  2KL5 A;  4DUR A;  4R1B A;  3SP8 A;  4YIZ A;  5CS5 A;  1I8N A;  2Z8V A;  5COE A;  2YIL A;  5CS1 A;  3HMR A;  2Z8W A;  5CP9 A;  5CT3 A;  4APM A;  2Q8A A;  4Z0F A;  2F83 A;  2X2Z A;  2Y8R A;  5CT2 A;  4R1C A;  2YIP A;  4A5T S;  1GP9 A;  5I25 A;  2QJ2 A;  3SRI A;  3SRJ A;  1GMN A;  4YIV A;  5CT1 A;  2J8J A;  4APL A;  4UV6 A;  3HMT A;  5CS3 A;  4Z0E A;  2YIO A;  5CSQ A;  3MKP A; 
#chains in the Genus database with same CATH homology
 1BHT A;  2HGF A;  1NK1 A;  1YXE A;  2Q8B A;  1HKY A;  2LL4 M;  3HMS A;  2LL3 A;  5EOK A;  2K13 X;  5EOD A;  1Z40 A;  4R1A A;  3ZWZ A;  1GMO A;  4R19 A;  1W81 A;  1W8K A;  4UAO A;  2QJ4 A;  5CS9 A;  4Z09 A;  2J8L A;  4Z0D A;  4IUA A;  3ZLE A;  3HN4 A;  2KL5 A;  4DUR A;  4R1B A;  3SP8 A;  4YIZ A;  5CS5 A;  1I8N A;  2Z8V A;  5COE A;  2YIL A;  5CS1 A;  3HMR A;  2Z8W A;  5CP9 A;  5CT3 A;  4APM A;  2Q8A A;  4Z0F A;  2F83 A;  2X2Z A;  2Y8R A;  5CT2 A;  4R1C A;  2YIP A;  4A5T S;  1GP9 A;  5I25 A;  2QJ2 A;  3SRI A;  3SRJ A;  1GMN A;  4YIV A;  5CT1 A;  2J8J A;  4APL A;  4UV6 A;  3HMT A;  5CS3 A;  4Z0E A;  2YIO A;  5CSQ A;  3MKP A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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