2K13X

Solution nmr structure of the leech protein saratin, a novel inhibitor of haemostasis
Total Genus 21
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
21
sequence length
103
structure length
103
Chain Sequence
EEREDCWTFYANRKYTDFDKSFKKSSDLDECKKTCFKTEYCYIVFEDTVNKECYYNVVDGEELDQEKFVVDENFTENYLTDCEGKDAGNAAGTGDESDEVDED
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structure of the leech protein saratin and characterization of its binding to collagen
pubmed doi rcsb
molecule keywords Saratin
molecule tags Toxin
total genus 21
structure length 103
sequence length 103
ec nomenclature
pdb deposition date 2008-02-20
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.50.4.10 Alpha Beta 3-Layer(bba) Sandwich Hepatocyte Growth Factor Hepatocyte Growth Factor 2k13X00
2Z8VA 4Z0DA 2K13X 2Q8BA 1W81A 4R1AA 3ZWZA 4DURA 4IUAA 4UAOA 1I8NA 4A5TS 4R19A 2Z8WA 3SP8A 5I25A 1BHTA 4R1CA 4UV6A 2QJ2A 1HKYA 2J8LA 2LL3A 1YXEA 5COEA 4Z0EA 5CT1A 2X2ZA 2YILA 3HN4A 5CS5A 1W8KA 3MKPA 5EODA 1GMNA 5EOKA 1Z40A 2LL4M 2Q8AA 1GP9A 3SRJA 2Y8RA 2F83A 5CT2A 4R1BA 3SRIA 4APLA 5CS1A 1GMOA 2QJ4A 2YIOA 3HMRA 3ZLEA 4APMA 5CS3A 2HGFA 3HMTA 1NK1A 2J8JA 4Z09A 4Z0FA 5CSQA 3HMSA 5CP9A 5CS9A 5CT3A 2YIPA
chains in the Genus database with same CATH superfamily
2Z8VA 4Z0DA 2K13X 2Q8BA 1W81A 4YIZA 4R1AA 3ZWZA 4DURA 4IUAA 4UAOA 1I8NA 4A5TS 4R19A 2Z8WA 3SP8A 5I25A 1BHTA 4R1CA 4UV6A 2QJ2A 1HKYA 2J8LA 2LL3A 1YXEA 5COEA 4YIVA 4Z0EA 5CT1A 2X2ZA 2YILA 3HN4A 5CS5A 1W8KA 3MKPA 2KL5A 1GMNA 5EOKA 5EODA 1Z40A 2LL4M 2Q8AA 1GP9A 3SRJA 2Y8RA 2F83A 5CT2A 4R1BA 3SRIA 4APLA 5CS1A 1GMOA 2QJ4A 2YIOA 3HMRA 3ZLEA 4APMA 5CS3A 2HGFA 3HMTA 1NK1A 2J8JA 4Z09A 4Z0FA 5CSQA 3HMSA 5CP9A 5CS9A 5CT3A 2YIPA
chains in the Genus database with same CATH topology
2Z8VA 4Z0DA 2K13X 2Q8BA 1W81A 4YIZA 4R1AA 3ZWZA 4DURA 4IUAA 4UAOA 1I8NA 4A5TS 4R19A 2Z8WA 3SP8A 5I25A 1BHTA 4R1CA 4UV6A 2QJ2A 1HKYA 2J8LA 2LL3A 1YXEA 5COEA 4YIVA 4Z0EA 5CT1A 2X2ZA 2YILA 3HN4A 5CS5A 1W8KA 3MKPA 2KL5A 1GMNA 5EOKA 5EODA 1Z40A 2LL4M 2Q8AA 1GP9A 3SRJA 2Y8RA 2F83A 5CT2A 4R1BA 3SRIA 4APLA 5CS1A 1GMOA 2QJ4A 2YIOA 3HMRA 3ZLEA 4APMA 5CS3A 2HGFA 3HMTA 1NK1A 2J8JA 4Z09A 4Z0FA 5CSQA 3HMSA 5CP9A 5CS9A 5CT3A 2YIPA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2Z8V A;  4Z0D A;  2K13 X;  2Q8B A;  1W81 A;  4R1A A;  3ZWZ A;  4DUR A;  4IUA A;  4UAO A;  1I8N A;  4A5T S;  4R19 A;  2Z8W A;  3SP8 A;  5I25 A;  1BHT A;  4R1C A;  4UV6 A;  2QJ2 A;  1HKY A;  2J8L A;  2LL3 A;  1YXE A;  5COE A;  4Z0E A;  5CT1 A;  2X2Z A;  2YIL A;  3HN4 A;  5CS5 A;  1W8K A;  3MKP A;  5EOD A;  1GMN A;  5EOK A;  1Z40 A;  2LL4 M;  2Q8A A;  1GP9 A;  3SRJ A;  2Y8R A;  2F83 A;  5CT2 A;  4R1B A;  3SRI A;  4APL A;  5CS1 A;  1GMO A;  2QJ4 A;  2YIO A;  3HMR A;  3ZLE A;  4APM A;  5CS3 A;  2HGF A;  3HMT A;  1NK1 A;  2J8J A;  4Z09 A;  4Z0F A;  5CSQ A;  3HMS A;  5CP9 A;  5CS9 A;  5CT3 A;  2YIP A; 
#chains in the Genus database with same CATH topology
 2Z8V A;  4Z0D A;  2K13 X;  2Q8B A;  1W81 A;  4YIZ A;  4R1A A;  3ZWZ A;  4DUR A;  4IUA A;  4UAO A;  1I8N A;  4A5T S;  4R19 A;  2Z8W A;  3SP8 A;  5I25 A;  1BHT A;  4R1C A;  4UV6 A;  2QJ2 A;  1HKY A;  2J8L A;  2LL3 A;  1YXE A;  5COE A;  4YIV A;  4Z0E A;  5CT1 A;  2X2Z A;  2YIL A;  3HN4 A;  5CS5 A;  1W8K A;  3MKP A;  2KL5 A;  1GMN A;  5EOK A;  5EOD A;  1Z40 A;  2LL4 M;  2Q8A A;  1GP9 A;  3SRJ A;  2Y8R A;  2F83 A;  5CT2 A;  4R1B A;  3SRI A;  4APL A;  5CS1 A;  1GMO A;  2QJ4 A;  2YIO A;  3HMR A;  3ZLE A;  4APM A;  5CS3 A;  2HGF A;  3HMT A;  1NK1 A;  2J8J A;  4Z09 A;  4Z0F A;  5CSQ A;  3HMS A;  5CP9 A;  5CS9 A;  5CT3 A;  2YIP A; 
#chains in the Genus database with same CATH homology
 2Z8V A;  4Z0D A;  2K13 X;  2Q8B A;  1W81 A;  4YIZ A;  4R1A A;  3ZWZ A;  4DUR A;  4IUA A;  4UAO A;  1I8N A;  4A5T S;  4R19 A;  2Z8W A;  3SP8 A;  5I25 A;  1BHT A;  4R1C A;  4UV6 A;  2QJ2 A;  1HKY A;  2J8L A;  2LL3 A;  1YXE A;  5COE A;  4YIV A;  4Z0E A;  5CT1 A;  2X2Z A;  2YIL A;  3HN4 A;  5CS5 A;  1W8K A;  3MKP A;  2KL5 A;  1GMN A;  5EOK A;  5EOD A;  1Z40 A;  2LL4 M;  2Q8A A;  1GP9 A;  3SRJ A;  2Y8R A;  2F83 A;  5CT2 A;  4R1B A;  3SRI A;  4APL A;  5CS1 A;  1GMO A;  2QJ4 A;  2YIO A;  3HMR A;  3ZLE A;  4APM A;  5CS3 A;  2HGF A;  3HMT A;  1NK1 A;  2J8J A;  4Z09 A;  4Z0F A;  5CSQ A;  3HMS A;  5CP9 A;  5CS9 A;  5CT3 A;  2YIP A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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