2Q8AA

Structure of the malaria antigen ama1 in complex with a growth-inhibitory antibody
Total Genus 97
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
97
sequence length
332
structure length
316
Chain Sequence
GNPWTEYMAKYDIEEVHGSGIRVDLGEDAEVAGTQYRLPSGKCPVFGKGIIIENSNTTFLTPVATGNQYLKDGGFAFPPTEPLMSPMTLDEMRHFYKDNKYVKNLDELTLCSRHAGNMIPDNDKNSNYKYPAVYDDKDKKCHILYIAAQENNGPRYCNKDESKRNSMFCFRPAKDISFQNYTYLSKNVVDNWEKVCPRKNLQNAKFGLWVDGNCEDIPHVNEFPAIDLFECNKLVFELSASDQPEQHLTDYEKIKEGFKNKNASMIKYKSHGKGYNWGNYNTETQKCEIFNVKPTCLINNSSYIATTALSHPIEVE
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structure of the malaria antigen AMA1 in complex with a growth-inhibitory antibody.
pubmed doi rcsb
molecule keywords Apical membrane antigen 1
molecule tags Immune system
source organism Plasmodium falciparum
total genus 97
structure length 316
sequence length 332
ec nomenclature
pdb deposition date 2007-06-10
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.50.4.10 Alpha Beta 3-Layer(bba) Sandwich Hepatocyte Growth Factor Hepatocyte Growth Factor 2q8aA01
5CS9A 3HN4A 1GMNA 4R19A 1GP9A 2YIPA 3HMSA 1I8NA 2F83A 1GMOA 4IUAA 4Z09A 5CSQA 1W8KA 1YXEA 2HGFA 2J8LA 2LL3A 2X2ZA 2YILA 3HMRA 4R1BA 5CP9A 2Y8RA 2Q8BA 1W81A 4Z0EA 3SRIA 5CT2A 2Q8AA 2Z8VA 4Z0DA 4R1AA 5I25A 5EOKA 4UAOA 5CT1A 4DURA 4APLA 5CT3A 1Z40A 3HMTA 5EODA 3MKPA 2J8JA 5COEA 3ZWZA 4APMA 4Z0FA 2YIOA 2Z8WA 4R1CA 2QJ4A 1HKYA 5CS1A 5CS5A 3SRJA 3ZLEA 3SP8A 5CS3A 1BHTA 4UV6A 2LL4M 4A5TS 1NK1A 2K13X 2QJ2A
chains in the Genus database with same CATH superfamily
5CS9A 3HN4A 1GMNA 4R19A 1GP9A 2YIPA 3HMSA 1I8NA 2F83A 1GMOA 4IUAA 4Z09A 5CSQA 1W8KA 1YXEA 2HGFA 2J8LA 2LL3A 2X2ZA 2YILA 3HMRA 4R1BA 5CP9A 2Y8RA 2Q8BA 1W81A 4Z0EA 3SRIA 5CT2A 4YIVA 2Q8AA 2Z8VA 4Z0DA 4R1AA 4YIZA 5I25A 5EOKA 4UAOA 5CT1A 2KL5A 4DURA 4APLA 5CT3A 1Z40A 3HMTA 5EODA 3MKPA 2J8JA 5COEA 3ZWZA 4APMA 4Z0FA 2YIOA 2Z8WA 4R1CA 2QJ4A 1HKYA 5CS1A 5CS5A 3SRJA 3ZLEA 3SP8A 5CS3A 1BHTA 4UV6A 2LL4M 4A5TS 1NK1A 2K13X 2QJ2A
chains in the Genus database with same CATH topology
5CS9A 3HN4A 1GMNA 4R19A 1GP9A 2YIPA 3HMSA 1I8NA 2F83A 1GMOA 4IUAA 4Z09A 5CSQA 1W8KA 1YXEA 2HGFA 2J8LA 2LL3A 2X2ZA 2YILA 3HMRA 4R1BA 5CP9A 2Y8RA 2Q8BA 1W81A 4Z0EA 3SRIA 5CT2A 4YIVA 2Q8AA 2Z8VA 4Z0DA 4R1AA 4YIZA 5I25A 5EOKA 4UAOA 5CT1A 2KL5A 4DURA 4APLA 5CT3A 1Z40A 3HMTA 5EODA 3MKPA 2J8JA 5COEA 3ZWZA 4APMA 4Z0FA 2YIOA 2Z8WA 4R1CA 2QJ4A 1HKYA 5CS1A 5CS5A 3SRJA 3ZLEA 3SP8A 5CS3A 1BHTA 4UV6A 2LL4M 4A5TS 1NK1A 2K13X 2QJ2A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 5CS9 A;  3HN4 A;  1GMN A;  4R19 A;  1GP9 A;  2YIP A;  3HMS A;  1I8N A;  2F83 A;  1GMO A;  4IUA A;  4Z09 A;  5CSQ A;  1W8K A;  1YXE A;  2HGF A;  2J8L A;  2LL3 A;  2X2Z A;  2YIL A;  3HMR A;  4R1B A;  5CP9 A;  2Y8R A;  2Q8B A;  1W81 A;  4Z0E A;  3SRI A;  5CT2 A;  2Q8A A;  2Z8V A;  4Z0D A;  4R1A A;  5I25 A;  5EOK A;  4UAO A;  5CT1 A;  4DUR A;  4APL A;  5CT3 A;  1Z40 A;  3HMT A;  5EOD A;  3MKP A;  2J8J A;  5COE A;  3ZWZ A;  4APM A;  4Z0F A;  2YIO A;  2Z8W A;  4R1C A;  2QJ4 A;  1HKY A;  5CS1 A;  5CS5 A;  3SRJ A;  3ZLE A;  3SP8 A;  5CS3 A;  1BHT A;  4UV6 A;  2LL4 M;  4A5T S;  1NK1 A;  2K13 X;  2QJ2 A; 
#chains in the Genus database with same CATH topology
 5CS9 A;  3HN4 A;  1GMN A;  4R19 A;  1GP9 A;  2YIP A;  3HMS A;  1I8N A;  2F83 A;  1GMO A;  4IUA A;  4Z09 A;  5CSQ A;  1W8K A;  1YXE A;  2HGF A;  2J8L A;  2LL3 A;  2X2Z A;  2YIL A;  3HMR A;  4R1B A;  5CP9 A;  2Y8R A;  2Q8B A;  1W81 A;  4Z0E A;  3SRI A;  5CT2 A;  4YIV A;  2Q8A A;  2Z8V A;  4Z0D A;  4R1A A;  4YIZ A;  5I25 A;  5EOK A;  4UAO A;  5CT1 A;  2KL5 A;  4DUR A;  4APL A;  5CT3 A;  1Z40 A;  3HMT A;  5EOD A;  3MKP A;  2J8J A;  5COE A;  3ZWZ A;  4APM A;  4Z0F A;  2YIO A;  2Z8W A;  4R1C A;  2QJ4 A;  1HKY A;  5CS1 A;  5CS5 A;  3SRJ A;  3ZLE A;  3SP8 A;  5CS3 A;  1BHT A;  4UV6 A;  2LL4 M;  4A5T S;  1NK1 A;  2K13 X;  2QJ2 A; 
#chains in the Genus database with same CATH homology
 5CS9 A;  3HN4 A;  1GMN A;  4R19 A;  1GP9 A;  2YIP A;  3HMS A;  1I8N A;  2F83 A;  1GMO A;  4IUA A;  4Z09 A;  5CSQ A;  1W8K A;  1YXE A;  2HGF A;  2J8L A;  2LL3 A;  2X2Z A;  2YIL A;  3HMR A;  4R1B A;  5CP9 A;  2Y8R A;  2Q8B A;  1W81 A;  4Z0E A;  3SRI A;  5CT2 A;  4YIV A;  2Q8A A;  2Z8V A;  4Z0D A;  4R1A A;  4YIZ A;  5I25 A;  5EOK A;  4UAO A;  5CT1 A;  2KL5 A;  4DUR A;  4APL A;  5CT3 A;  1Z40 A;  3HMT A;  5EOD A;  3MKP A;  2J8J A;  5COE A;  3ZWZ A;  4APM A;  4Z0F A;  2YIO A;  2Z8W A;  4R1C A;  2QJ4 A;  1HKY A;  5CS1 A;  5CS5 A;  3SRJ A;  3ZLE A;  3SP8 A;  5CS3 A;  1BHT A;  4UV6 A;  2LL4 M;  4A5T S;  1NK1 A;  2K13 X;  2QJ2 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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